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Journal Articles

Proximity proteomics identifies septins and PAK2 as decisive regulators of actomyosin-mediated expulsion of von Willebrand factor

Sammy El-Mansi, Christopher L. Robinson, Katja B. Kostelnik, Jessica J. McCormack, Tom P. Mitchell, Damián Lobato-Márquez, Vinothini Rajeeve, Pedro Cutillas, Daniel F. Cutler, Serge Mostowy, Thomas D. Nightingale

Blood (2023) 141 (8): 930–944.

https://doi.org/10.1182/blood.2022017419

Published: 2023

Includes: Supplemental data

Journal Articles

Inhibition of Stearoyl-CoA Desaturase Has Anti-Leukemic Properties in Acute Myeloid Leukemia

Blood (2022) 140 (Supplement 1): 3058–3060.

https://doi.org/10.1182/blood-2022-166811

Published: 2022

Journal Articles

Deep Multi-Omics Profiling in Cytogenetically Poor-Risk AML

Blood (2022) 140 (Supplement 1): 1030–1032.

https://doi.org/10.1182/blood-2022-159069

Published: 2022

Journal Articles

Proteomics and Phospho-Proteomics Reveal Predictive Signatures of Response and Mechanisms of Resistance to Midostaurin Plus Chemotherapy in FLT3 Mutant Positive Acute Myeloid Leukemia

Luis Miguel Veiga Veiga Nobre, Salvatore Federico Pedicona, Arran Dokal, Andrea Arruda, Ryan Smith, Calum Greenhalgh, Francesca Patella, Pedro Casado-Izquierdo, Bela Wrench, Jane Theaker, Andrew Thompson, Mark D. Minden, John G. Gribben, David James Britton, Pedro Cutillas

Blood (2021) 138 (Supplement 1): 3462.

https://doi.org/10.1182/blood-2021-152379

Published: 2021

Journal Articles

KDM5 inhibition offers a novel therapeutic strategy for the treatment of KMT2D mutant lymphomas

Blood (2021) 138 (5): 370–381.

https://doi.org/10.1182/blood.2020008743

Published: 2021

Includes: Supplemental data

Journal Articles

Integration of Deep Multi-Omics Profiling Veals New Insights into the Biology of Poor-Risk Acute Myeloid Leukemia

Blood (2020) 136 (Supplement 1): 39–40.

https://doi.org/10.1182/blood-2020-141345

Published: 2020

Journal Articles

Combination Therapy Targeting CKS1-Dependent Protein Degradation Reduces AML Burden Whilst Protecting Normal Haematopoietic Stem Cellsfrom Cytarabine Toxicity

William Grey, PhD MSc, Pedro Casado-Izquierdo, Pedro Cutillas, PhD, Dominique Bonnet, PhD

Blood (2019) 134 (Supplement_1): 2535.

https://doi.org/10.1182/blood-2019-121667

Published: 2019

Journal Articles

Rituximab and Obinutuzumab Induce Direct B-Cell Death Via B-Cell Receptor (BCR) Signaling, but Rituximab Elicits Stronger BCR-Derived Pro-Survival Signals Diminishing Apoptosis

Jennifer Edelmann, MD PhD, Arran Dokal, MSc, PhD, Karlheinz Holzmann, Dr. rer. nat., David James Britton, BSc, PhD, Emma Vilventhraraja, MSc, PhD, Ryan Jack Smith, PhD, Mark S Cragg, Prof, Andrejs Braun, PhD, Hartmut Döhner, MD, Pedro Cutillas, PhD, John G. Gribben, MD DSc

Blood (2019) 134 (Supplement_1): 1579.

https://doi.org/10.1182/blood-2019-128704

Published: 2019

Journal Articles

Anti-CD20 Monoclonal Antibodies Hijack the B-Cell Receptor Signaling Cascade Thereby Activating the NOTCH1 Signaling Pathway

Jennifer Edelmann, MD, David James Britton, BSc, PhD, Emma Vilventhraraja, MSc, PhD, Arran Dokal, MSc, PhD, Karlheinz Holzmann, Dr. rer. nat., Mark C Cragg, Andrejs Braun, PhD, Pedro Cutillas, PhD, John G. Gribben

Blood (2018) 132 (Supplement 1): 588.

https://doi.org/10.1182/blood-2018-99-116490

Published: 2018

Journal Articles

Sustained Reduction of Intracellular Calcium Is Important to Maximise GA101-Mediated Direct Cell Death in B-Cell Lymphomas

Emma Vilventhraraja, Jennifer Edelmann, MD PhD, Faith Norster, Andrejs Braun, PhD, John G. Gribben, MDDSc FMedSci, Pedro Cutillas, PhD, Arran Dokal, MSc

Blood (2017) 130 (Supplement 1): 1269.

https://doi.org/10.1182/blood.V130.Suppl_1.1269.1269

Published: 2017

Journal Articles

Anergic Response to B-Cell Receptor Signaling in Chronic Lymphocytic Leukemia: The Differing Roles of IgD and IgM in the Microenvironment and Peripheral Blood.

Tom Butler, MD, Alexander Montoya, Andrew James Clear, BSc, Rita Coutinho, MD, David C Taussig, PhD, MRCP, FRCPath, Pedro Cutillas, PhD, John G Gribben

Blood (2012) 120 (21): 2889.

https://doi.org/10.1182/blood.V120.21.2889.2889

Published: 2012

NARROW

Proximity proteomics identifies septins and PAK2 as decisive regulators of actomyosin-mediated expulsion of von Willebrand factor

Inhibition of Stearoyl-CoA Desaturase Has Anti-Leukemic Properties in Acute Myeloid Leukemia

Deep Multi-Omics Profiling in Cytogenetically Poor-Risk AML

Proteomics and Phospho-Proteomics Reveal Predictive Signatures of Response and Mechanisms of Resistance to Midostaurin Plus Chemotherapy in FLT3 Mutant Positive Acute Myeloid Leukemia

KDM5 inhibition offers a novel therapeutic strategy for the treatment of KMT2D mutant lymphomas

Integration of Deep Multi-Omics Profiling Veals New Insights into the Biology of Poor-Risk Acute Myeloid Leukemia

Combination Therapy Targeting CKS1-Dependent Protein Degradation Reduces AML Burden Whilst Protecting Normal Haematopoietic Stem Cellsfrom Cytarabine Toxicity

Rituximab and Obinutuzumab Induce Direct B-Cell Death Via B-Cell Receptor (BCR) Signaling, but Rituximab Elicits Stronger BCR-Derived Pro-Survival Signals Diminishing Apoptosis

Anti-CD20 Monoclonal Antibodies Hijack the B-Cell Receptor Signaling Cascade Thereby Activating the NOTCH1 Signaling Pathway

Sustained Reduction of Intracellular Calcium Is Important to Maximise GA101-Mediated Direct Cell Death in B-Cell Lymphomas

Anergic Response to B-Cell Receptor Signaling in Chronic Lymphocytic Leukemia: The Differing Roles of IgD and IgM in the Microenvironment and Peripheral Blood.

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American Society of Hematology

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American Society of Hematology

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