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Journal Articles

Allele-Specific Expression of Leukemia Genes Is Associated with Pathogenicity in Poor Risk AML

Jiexin Zheng, Findlay Bewicke-Copley, Carlo Vermeulen, Pedro Casado, Fadimana Kaya, Jonas Demeulemeester, Molly Guscott, Szilvia Krizsán, Sam Benkwitz-Bedford, Farideh Miraki-Moud, Janet Matthews, Marianne Grantham, Doriana Di Bella, John G. Gribben, James Cavenagh, Peter Van Loo, Sarah McClelland, Csaba Bödör, Jean-Baptiste Cazier, David Taussig, Dominique Bonnet, Pedro R Cutillas, Jun Wang, Jeroen De Ridder, Jude Fitzgibbon, Ana Rio-Machin
Journal: Blood
Blood (2023) 142 (Supplement 1): 1389.
https://doi.org/10.1182/blood-2023-184516
Published: 2023
Journal Articles

Deep Multi-Omics Profiling in Cytogenetically Poor-Risk AML

Ana Rio-Machin, Findlay Bewicke-Copley, Jiexin Zheng, Pedro Casado Izquierdo, Juho J. Miettinen, Naeem Khan, Jonas Demeulemeester, Szilvia Krizsán, Christopher Middleton, Sam Benkwitz-Bedford, Joseph Saad, Amaia Vilas-Zornoza, Teresa Ezponda, William Grey, Vincent-Philippe Lavallée, Alexis Nolin-Lapalme, Farideh Miraki-Moud, Janet Matthews, Marianne Grantham, Ryan J Colm, Jonathan Bond, Doriana Di Bella, Krister Wennerberg, Alun Parsons, Andy G.X. Zeng, Hannah Armes, Karina Close, Fadimana Kaya, Kevin Rouault-Pierre, John G. Gribben, Felipe Prosper, James Cavenagh, John E. Dick, Sylvie D Freeman, Peter Van Loo, Csaba Bödör, Guy Sauvageau, Kimmo Porkka, Caroline A. Heckman, Jun Wang, Jean-Baptiste Cazier, David Taussig, Dominique Bonnet, Pedro Cutillas, Jude Fitzgibbon
Journal: Blood
Blood (2022) 140 (Supplement 1): 1030–1032.
https://doi.org/10.1182/blood-2022-159069
Published: 2022
Journal Articles

Impact of Autologous Stem Cell Transplant (ASCT) Versus Consolidation on Health-Related Quality of Life (HRQoL) for Patients with Multiple Myeloma Receiving Carfilzomib Maintenance: Results from the Cardamon Trial

Rakesh Popat, William Wilson, Marquita Camilleri, Karthik Ramasamy, Matthew Streetly, Jonathan Sive, Ceri Bygrave, Reuben Benjamin, Michael A Chapman, Selina J Chavda, Beth Phillips, Maria del Mar Cuadrado, Gavin Pang, Richard Jenner, Tushhar Dadaga, Sumaiya Kamora, Ruth M. de Tute, James Cavenagh, Laura Clifton-Hadley, Roger G Owen, Kwee Yong
Journal: Blood
Blood (2022) 140 (Supplement 1): 10191–10192.
https://doi.org/10.1182/blood-2022-166344
Published: 2022
Journal Articles

Developing a Flow Cytometric Signature of Carfilzomib Responsiveness in Myeloma

Ieuan Walker, Venetia D'arcy, Antonio Rodriguez Romera, Georgina Anderson, Anna Aubareda, James Roy, Garima Khandelwal, William Wilson, Evelyn Fitzsimons, Daria Galas-Filipowicz, Kane Foster, Rakesh Popat, Karthik Ramasamy, Matthew Streetly, Ceri Bygrave, Reuben Benjamin, Ruth M. de Tute, Marquita Camilleri, Selina J Chavda, Gavin Pang, Tushhar Dadaga, Sumaiya Kamora, James Cavenagh, Elizabeth H. Phillips, Laura Clifton-Hadley, Roger G Owen, Javier Herrero, Kwee Yong, Michael A Chapman
Journal: Blood
Blood (2022) 140 (Supplement 1): 10106–10107.
https://doi.org/10.1182/blood-2022-169882
Published: 2022
Journal Articles

PET-CT for Assessment of Multiple Myeloma Disease Burden and Metabolic Response before and after Carfilzomib-Based Induction, Consolidation and Carfilzomib Maintenance Therapy: Data from the UK NCRI Cardamon Study

Ceri A Bygrave, Manil Subesinghe, William Wilson, Rakesh Popat, Karthik Ramasamy, Gavin Pang, Richard Jenner, Sumaiya Kamora, Tushhar Dadaga, Lucy Pike, Matthew Streetly, Marquita Camilleri, Roger G Owen, James Cavenagh, Jonathan Sive, Michael Chapman, Elizabeth H Phillips, Selina J Chavda, Maria del Mar Cuadrado, Reuben Benjamin, Lydia Eccersley, Sally Moore, Lalita Banerjee, Laura Clifton-Hadley, Sally F Barrington, Kwee Yong
Journal: Blood
Blood (2021) 138 (Supplement 1): 2750.
https://doi.org/10.1182/blood-2021-150177
Published: 2021
Journal Articles

Upfront Autologous Stem Cell Transplantation (ASCT) Vs Carfilzomib-Cyclophosphamide-Dexamethasone (KCd) Consolidation in Transplant-Eligible, Newly Diagnosed (NDTE) Multiple Myeloma (MM): Results of the Cardamon Study According to Cytogenetic Risk

Kwee Yong, William Wilson, Marquita Camilleri, Karthik Ramasamy, Matthew Streetly, Jonathan Sive, Ceri A Bygrave, Michael Chapman, Ruth M. de Tute, Selina J Chavda, Elizabeth H Phillips, Maria del Mar Cuadrado, Gavin Pang, Richard Jenner, Tushhar Dadaga, Sumaiya Kamora, James Cavenagh, Laura Clifton-Hadley, Roger G Owen, Rakesh Popat
Journal: Blood
Blood (2021) 138 (Supplement 1): 2911.
https://doi.org/10.1182/blood-2021-147771
Published: 2021
Journal Articles

Integration of Deep Multi-Omics Profiling Veals New Insights into the Biology of Poor-Risk Acute Myeloid Leukemia

Ana Rio-Machin, Pedro Casado-Izquierdo, Juho Miettinen, PhD, Findlay Bewicke-Copley, PhD MSc, BSc, Naeem Khan, PhD, Jonas Demeulemeester, Szilvia Krizsán, MD, Jiexin Zheng, Christopher Middleton, Wencheng Yin, William Grey, Farideh Miraki-Moud, PhD, Janet Matthews, Marianne Grantham, Kevin Rouault-Pierre, PhD, Krister Wennerberg, Alun Parsons, Hannah Armes, Karina EM Close, Doriana Di Bella, James Cavenagh, Sylvie D Freeman, Peter Van Loo, Csaba Bödör, PhD, Kimmo Porkka, Caroline A Heckman, PhD, Jun Wang, PhD, David Taussig, Dominique Bonnet, PhD, Jean-Baptiste Cazier, PhD, Pedro Cutillas, PhD, Jude Fitzgibbon, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 39–40.
https://doi.org/10.1182/blood-2020-141345
Published: 2020
Journal Articles

Efficacy and Safety of Azacitidine (AZA) in Combination with the Anti-PD-L1 Durvalumab (durva) for the Front-Line Treatment of Older Patients (pts) with Acute Myeloid Leukemia (AML) Who Are Unfit for Intensive Chemotherapy (IC) and Pts with Higher-Risk Myelodysplastic Syndromes (HR-MDS): Results from a Large, International, Randomized Phase 2 Study

Amer M. Zeidan, MBBS, MHS, James Cavenagh, Maria Teresa Voso, David Taussig, Mar Tormo, Isaac Boss, Wilbert B. Copeland, Vanessa E. Gray, Alessandro Previtali, Tim O'Connor, Shelonitda Rose, CL Beach, Lewis R. Silverman
Journal: Blood
Blood (2019) 134 (Supplement_1): 829.
https://doi.org/10.1182/blood-2019-122896
Published: 2019
Journal Articles

International phase 3 study of azacitidine vs conventional care regimens in older patients with newly diagnosed AML with >30% blasts

Clinical Trials & Observations
Hervé Dombret, John F. Seymour, Aleksandra Butrym, Agnieszka Wierzbowska, Dominik Selleslag, Jun Ho Jang, Rajat Kumar, James Cavenagh, Andre C. Schuh, Anna Candoni, Christian Récher, Irwindeep Sandhu, Teresa Bernal del Castillo, Haifa Kathrin Al-Ali, Giovanni Martinelli, Jose Falantes, Richard Noppeney, Richard M. Stone, Mark D. Minden, Heidi McIntyre, Steve Songer, Lela M. Lucy, C. L. Beach, Hartmut Döhner
Journal: Blood
Blood (2015) 126 (3): 291–299.
https://doi.org/10.1182/blood-2015-01-621664
Published: 2015
Includes: Supplemental data
Journal Articles

A Novel Heat Shock Protein (HSP) 90 Inhibitor KW-2478 shows Activity in B-Cell Malignancies in Vitro and in Vivo.

Simone Juliger, Takayuki Nakashima, Lenushka Maharaj, Toshihiko Ishii, Hiroshi Nakagawa, Yutaka Kanda, Heather Oakervee, James Cavenagh, Shiro Akinaga, Yukimasa Shiotsu, Simon P Joel
Journal: Blood
Blood (2008) 112 (11): 1625.
https://doi.org/10.1182/blood.V112.11.1625.1625
Published: 2008