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Journal Articles

Isomarker: An Explainable Machine Learning Framework for Identification of Cell State Markers in Acute Myeloid Leukemia

David Chen, Suraj Bansal, Amanda Mitchell, Anne Maria Tierens, Andy G.X. Zeng, John E. Dick

Blood (2024) 144 (Supplement 1): 1542.

https://doi.org/10.1182/blood-2024-210986

Published: 2024

Journal Articles

Hallmarks of Transcriptional Heterogeneity in Human Hematopoietic Stem Cells across 382 Donors

Sayyam Shah, Murtaza S. Nagree, Chhiring Lama, Anna S. Nam, Andy G.X. Zeng, Stephanie Z Xie, John E. Dick

Blood (2024) 144 (Supplement 1): 1281.

https://doi.org/10.1182/blood-2024-212079

Published: 2024

Journal Articles

ATLAS-AML: An Automated Bioinformatics Pipeline for Drug Target Characterization in Acute Myeloid Leukemia

Suraj Bansal, David Chen, Amanda Mitchell, Andy G.X. Zeng, John E. Dick

Blood (2024) 144 (Supplement 1): 2924.

https://doi.org/10.1182/blood-2024-211344

Published: 2024

Journal Articles

Adaptation to ex vivo culture reduces human hematopoietic stem cell activity independently of the cell cycle

Blood (2024) 144 (7): 729–741.

https://doi.org/10.1182/blood.2023021426

Published: 2024

Includes: Supplemental data

Journal Articles

Identifying Stress Granules As Determinants of Leukemia Stem Cell Maintenance and Stress Adaptation

Blood (2023) 142 (Supplement 1): 405.

https://doi.org/10.1182/blood-2023-180919

Published: 2023

Journal Articles

Functional Deconvolution of the Leukemia Stem Cell Pool Uncovers Co-Existing Alternative Stem Cell Driven Hierarchies

Helena Boutzen, Alexander Murison, Sayyam Shah, Kerstin B Kaufmann, John E. Dick

Blood (2023) 142 (Supplement 1): 5679.

https://doi.org/10.1182/blood-2023-180207

Published: 2023

Journal Articles

Multiparametric Flow Cytometry Based Quantification of the Marrow Hematopoietic Stem and Progenitor Compartment in Post Allogeneic Stem Cell Transplant Recipients with Poor Graft Function to Evaluate Hematopoietic Stem Cell Quality and Predict Clinical Outcomes: A Pilot Study

Niranjan Shiwaji Khaire, Murtaza S. Nagree, Mason Boulanger, Carol Chen, John E. Dick, Jonas Mattsson, Stephanie Xie

Blood (2023) 142 (Supplement 1): 6784.

https://doi.org/10.1182/blood-2023-182171

Published: 2023

Journal Articles

Single Cell Transcriptomic Analysis of B-Cell Acute Lymphoblastic Leukemia (B-ALL) Reveals Correlation between Leukemia Cell State, Genetic Alterations and Clinical Outcome

Ilaria Iacobucci, Andy G.X. Zeng, Qingsong Gao, Laura Garcia Prat, Pradyumna Baviskar, Sayyam Shah, Alexander Murison, Veronique Voisin, Colin Bailey, Matthew Lear, Anjali S. Advani, Selina M Luger, Elisabeth Paietta, Wendy Stock, John E. Dick, Charles G. Mullighan

Blood (2023) 142 (Supplement 1): 841.

https://doi.org/10.1182/blood-2023-190180

Published: 2023

Journal Articles

Cellular and Molecular Analysis of Hematopoietic Stem and Progenitor Cells in Shwachman-Diamond Syndrome

Apichat Photia, Mariana Benicio, Efe Sahinoglu, Hongbing Li, Richard Neil Armstrong, Houtan Moshiri, Robert J. Klaassen, Yves D Pastore, John E. Dick, Yigal Dror

Blood (2023) 142 (Supplement 1): 1364.

https://doi.org/10.1182/blood-2023-190722

Published: 2023

Journal Articles

Precise Single-Cell Transcriptomic Mapping of Leukemia Cell States Reveals Unconventional Lineage Priming in Acute Myeloid Leukemia

Andy G.X. Zeng, Ilaria Iacobucci, Sayyam Shah, Gordon Wong, Amanda Mitchell, Qingsong Gao, Hyerin Kim, Mark D. Minden, Torsten Haferlach, Charles G. Mullighan, John E. Dick

Blood (2023) 142 (Supplement 1): 1593.

https://doi.org/10.1182/blood-2023-189697

Published: 2023

Journal Articles

XPO2 Is Essential for a Subset of AML Cells and Is a Biomarker for Poor Response and Survival in Pediatric and AYA AML

Grace Egan, Geethu Emily Thomas, Rose Hurren, Suraj Bansal, Andy G.X. Zeng, Chaitra Sarathy, Dilshad H. Khan, Yongran Yan, Yue Feng, Jonathan St-Germain, Brian Raught, John E. Dick, Aaron D. Schimmer

Blood (2023) 142 (Supplement 1): 5681.

https://doi.org/10.1182/blood-2023-180968

Published: 2023

Journal Articles

Somatic TET2 Mutations Prime the Immune System for Response to Immune Checkpoint Blockade

Robert Vanner, Andy G.X. Zeng, Michelle Chan-Seng-Yue, Suraj Bansal, Elisa Donato, Liqing Jin, Sofia Genta, Enrique Sanz Garcia, Steven M. Chan, Andreas Trumpp, John E. Dick

Blood (2023) 142 (Supplement 1): 2689.

https://doi.org/10.1182/blood-2023-177740

Published: 2023

Journal Articles

Inflammatory Signatures Define a New High-Risk T-Lineage ALL Subtype

Blood (2023) 142 (Supplement 1): 2969.

https://doi.org/10.1182/blood-2023-182412

Published: 2023

Journal Articles

Circadian Rhythms Metabolically Regulate Bone Marrow Retained Primitive Hematopoietic Stem Cell Size and Function

Priyasmita Chakrabarti, Nicola K. Wilson, Abhishek K. Singh, Iwo Kucinski, Lizeth-Alejandra Ordonez-Moreno, Sony Sharma, Sarah J. Kinston, Montaser B. Haddad, Orit Kollet, Ekaterina Petrovich-Kopitman, Avik Choudhuri, Leonard I. Zon, Jose A. Cancelas, John E. Dick, Stephanie Xie, Bertie Göttgens, Tsvee Lapidot

Blood (2023) 142 (Supplement 1): 2672.

https://doi.org/10.1182/blood-2023-186260

Published: 2023

Journal Articles

Investigation of CD83 As a Novel Human Hematopoietic Stem Cell Inflammatory Activation Marker

Murtaza S. Nagree, Andy G.X. Zeng, Angelica Varesi, Isabel N.X. Lim, Sayyam Shah, Hyerin Kim, Liqing Jin, Mason Boulanger, John E. Dick, Stephanie Z. Xie

Blood (2023) 142 (Supplement 1): 4067.

https://doi.org/10.1182/blood-2023-187737

Published: 2023

Journal Articles

Stem Cell-Derived Gene Expression Scores Predict Survival and Leukemic Transformation in Myelofibrosis

Jessie J.F. Medeiros, Andy G.X. Zeng, Michelle Chan-Seng-Yue, Tristan Woo, Jessica L McLeod, Andrea Arruda, Hubert Tsui, Burhan Goraya, Jaime O. Claudio, Jenny M. Ho, James A. Kennedy, Dawn Maze, Hassan Sibai, Mark D. Minden, Jean C.Y. Wang, John E. Dick, Vikas Gupta

Blood (2022) 140 (Supplement 1): 9681–9682.

https://doi.org/10.1182/blood-2022-163722

Published: 2022

Journal Articles

Simultaneous Inhibition of SIRT3 and Cholesterol Homeostasis Targets AML Stem Cells By Perturbing Fatty Acid β-Oxidation and Inducing Lipotoxicity

Blood (2022) 140 (Supplement 1): 104–106.

https://doi.org/10.1182/blood-2022-157794

Published: 2022

Journal Articles

Identification of Global miRNA Targetomes within Human Hematopoietic Progenitors and Acute Myeloid Leukemia Uncovers Unique Molecular Networks Centered on Mitochondria Function in Leukemic Stem Cells

Gabriela Krivdova, Brian Yee, Stefan Aigner, Martino Gabra, Alexander Shishkin, Long Nguyen, Jessica L McLeod, Leah Carley, Leonardo Salmena, Lorien Shakib, Mark D. Minden, Eric L Van Nostrand, Gene W. Yeo, Eric R. Lechman, John E. Dick

Blood (2022) 140 (Supplement 1): 8684–8685.

https://doi.org/10.1182/blood-2022-169849

Published: 2022

Journal Articles

A Novel Role for PLK1 in Leukemia Stem Cell Function in Acute Myeloid Leukemia

Qiang Liu, Alex Murison, Andy G.X. Zeng, Changjiang Xu, Veronique Voisin, Faith Yeung, Amit Subedi, Steven M. Chan, Brian Raught, Gary D Bader, John E. Dick, Jean C.Y. Wang

Blood (2022) 140 (Supplement 1): 5920–5921.

https://doi.org/10.1182/blood-2022-169732

Published: 2022

Journal Articles

Discovery of a New Human Hematopoietic Stem Cell Involved with Aging That Retains Memory of Immune Activation

Andy G.X. Zeng, Murtaza S Nagree, Alexander Murison, Isabel Lim, Sayyam Shah, Alicia Aguilar-Navarro, Joana Araújo, Darrien Parris, Jessica L McLeod, Liqing Jin, Elvin Wagenblast, Eugenia Flores-Figueroa, John E. Dick, Stephanie Z Xie

Blood (2022) 140 (Supplement 1): 2218–2219.

https://doi.org/10.1182/blood-2022-170303

Published: 2022

NARROW

Isomarker: An Explainable Machine Learning Framework for Identification of Cell State Markers in Acute Myeloid Leukemia

Hallmarks of Transcriptional Heterogeneity in Human Hematopoietic Stem Cells across 382 Donors

ATLAS-AML: An Automated Bioinformatics Pipeline for Drug Target Characterization in Acute Myeloid Leukemia

Adaptation to ex vivo culture reduces human hematopoietic stem cell activity independently of the cell cycle

Identifying Stress Granules As Determinants of Leukemia Stem Cell Maintenance and Stress Adaptation

Functional Deconvolution of the Leukemia Stem Cell Pool Uncovers Co-Existing Alternative Stem Cell Driven Hierarchies

Multiparametric Flow Cytometry Based Quantification of the Marrow Hematopoietic Stem and Progenitor Compartment in Post Allogeneic Stem Cell Transplant Recipients with Poor Graft Function to Evaluate Hematopoietic Stem Cell Quality and Predict Clinical Outcomes: A Pilot Study

Single Cell Transcriptomic Analysis of B-Cell Acute Lymphoblastic Leukemia (B-ALL) Reveals Correlation between Leukemia Cell State, Genetic Alterations and Clinical Outcome

Cellular and Molecular Analysis of Hematopoietic Stem and Progenitor Cells in Shwachman-Diamond Syndrome

Precise Single-Cell Transcriptomic Mapping of Leukemia Cell States Reveals Unconventional Lineage Priming in Acute Myeloid Leukemia

XPO2 Is Essential for a Subset of AML Cells and Is a Biomarker for Poor Response and Survival in Pediatric and AYA AML

Somatic TET2 Mutations Prime the Immune System for Response to Immune Checkpoint Blockade

Inflammatory Signatures Define a New High-Risk T-Lineage ALL Subtype

Circadian Rhythms Metabolically Regulate Bone Marrow Retained Primitive Hematopoietic Stem Cell Size and Function

Investigation of CD83 As a Novel Human Hematopoietic Stem Cell Inflammatory Activation Marker

Stem Cell-Derived Gene Expression Scores Predict Survival and Leukemic Transformation in Myelofibrosis

Simultaneous Inhibition of SIRT3 and Cholesterol Homeostasis Targets AML Stem Cells By Perturbing Fatty Acid β-Oxidation and Inducing Lipotoxicity

Identification of Global miRNA Targetomes within Human Hematopoietic Progenitors and Acute Myeloid Leukemia Uncovers Unique Molecular Networks Centered on Mitochondria Function in Leukemic Stem Cells

A Novel Role for PLK1 in Leukemia Stem Cell Function in Acute Myeloid Leukemia

Discovery of a New Human Hematopoietic Stem Cell Involved with Aging That Retains Memory of Immune Activation

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American Society of Hematology

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American Society of Hematology

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