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Journal Articles

The Mitochondrial Unfolded Protein Response (UPR mt ) Is Upregulated in Acute Myeloid Leukemia (AML) and Inhibiting the UPR mt Protease, LONP1, Leads to Mitochondrial Protein Aggregation and Cell Death Selectively in AML

Matthew Tcheng, Veronique Voisin, Marcela Gronda, Rose Hurren, Dakai Ling, Yongran Yan, Lan Xin Zhang, Yue Feng, Zaynab Mamai, Yulia Jitkova, Chaitra Sarathy, Andrea Arruda, Steven M. Kornblau, Mark D. Minden, Aaron D Schimmer
Journal: Blood
Blood (2024) 144 (Supplement 1): 2778.
https://doi.org/10.1182/blood-2024-205308
Published: 2024
Journal Articles

The Exportin, CSE1L, Regulates Ribosome Biogenesis and Is a Selective Dependency in Childhood and Young Adult Acute Myeloid Leukemia

Grace Egan, Amit Kumar, Veronique Voisin, Rose Hurren, Ali Chegini, Dakai Ling, Geethu Emily Thomas, Youngran Yan, Yue Feng, Suraj Bansal, Andy G.X. Zeng, Andrea Arruda, John Edgar Dick, Gary D Bader, Mark D. Minden, Aaron D Schimmer
Journal: Blood
Blood (2024) 144 (Supplement 1): 2724.
https://doi.org/10.1182/blood-2024-200148
Published: 2024
Journal Articles

Integrated Stress Response Activation Induced By Usnic Acid Alleviates BCL-2 Inhibitor ABT-199 Resistance in Acute Myeloid Leukemia

Man Li, Jingjie Dong, Yaonan Hong, Li Jin, Chengtao Sun, Qi Liu, Liqin Li, Xiaoxiao Han, Shengqian Deng, Yue Feng, Yiping Shen, Guoyin Kai, Dijiong Wu
Journal: Blood
Blood (2024) 144 (Supplement 1): 4158.
https://doi.org/10.1182/blood-2024-198752
Published: 2024
Journal Articles

XPO2 Is Essential for a Subset of AML Cells and Is a Biomarker for Poor Response and Survival in Pediatric and AYA AML

Grace Egan, Geethu Emily Thomas, Rose Hurren, Suraj Bansal, Andy G.X. Zeng, Chaitra Sarathy, Dilshad H. Khan, Yongran Yan, Yue Feng, Jonathan St-Germain, Brian Raught, John E. Dick, Aaron D. Schimmer
Journal: Blood
Blood (2023) 142 (Supplement 1): 5681.
https://doi.org/10.1182/blood-2023-180968
Published: 2023
Journal Articles

Serine Phosphorylation Marks Proteins for Degradation By the Mitochondrial Serine Protease Complex, Clpxp

Yue Feng, Yulia Jitkova, Alexander Keszei, Chaitra Sarathy, Vincent Trudel, Jonathan St-Germain, Matthew Tcheng, Monica M Goncalves, Yongran Yan, Rose Hurren, Matthew Schultz, Siavash Vahidi, Brian Raught, Andrei Yudin, Mohammad Mazhab-Jafari, Aaron D. Schimmer
Journal: Blood
Blood (2023) 142 (Supplement 1): 5675.
https://doi.org/10.1182/blood-2023-173385
Published: 2023
Journal Articles

The Exportin, XPO2, Is a Novel Therapeutic Target in Pediatric, Adolescent and Young Adult AML

Grace Egan, Rose Hurren, Chaitra Sarathy, Geethu Emily Thomas, Dilshad H. Khan, Yongran Yan, Yue Feng, Brandon Brown, Steven M. Kornblau, Aaron D. Schimmer
Journal: Blood
Blood (2022) 140 (Supplement 1): 11504–11505.
https://doi.org/10.1182/blood-2022-157322
Published: 2022
Journal Articles

Phosphorylated Serine Marks Proteins for Degradation By the Mitochondrial Matrix Protease, Clpxp

Yue Feng, Yulia Jitkova, Alexander Keszei, Jonathan St-Germain, Yongran Yan, Brian Raught, Mohammad Mazhab-Jafari, Aaron D. Schimmer
Journal: Blood
Blood (2022) 140 (Supplement 1): 3023–3024.
https://doi.org/10.1182/blood-2022-157338
Published: 2022
Journal Articles

Nuclear Opening and Histone Release Are Essential for Nuclear but Not Chromatin Condensation during Terminal Erythropoiesis

Honghao Bi, Yijie Liu, Dongmei Wang, Ye Hou, Yue Feng, Peng Ji
Journal: Blood
Blood (2021) 138 (Supplement 1): 287.
https://doi.org/10.1182/blood-2021-150794
Published: 2021
Journal Articles

Serine and Threonine Phosphorylation Marks Proteins for Degradation By Clpxp

Yue Feng, Yulia Jitkova, Harjeet Soor, Suzanne Trudel, Kaitlin Lees, Kaylen Soriano, Siavash Vahidi, Andrei Yudin, Aaron D Schimmer
Journal: Blood
Blood (2021) 138 (Supplement 1): 3329.
https://doi.org/10.1182/blood-2021-146027
Published: 2021