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Journal Articles

A rapid gene expression profiler predicts tumor responsiveness and patient outcome for standard-of-care therapies in acute myeloid leukemia

Free
Christopher Eide, Stephen Kurtz, Andy Kaempf, Nicola Long, Alexandria Miller, Daniel Bottomly, Shannon McWeeney, Curtis Lachowiez, Sudarshan Anand, Stanley Ng, Jean Wang, John Dick, Jeffrey Tyner
Journal: Blood
Blood (2025) 146 (Supplement 1): 657.
https://doi.org/10.1182/blood-2025-657
Published: 2025
Journal Articles

Ribosome biogenesis and its regulation by the exportin, CSE1L, are targetable vulnerabilities in childhood and young adult Acute Myeloid Leukemia

Free
Grace Egan, Amit Kumar, Veronique Voisin, Rose Hurren, Ali Chegini, Dakai Ling, Geethu Thomas, Yongran Yan, Yue Feng, Nathan Duong, Dilshad Khan, Chaitra Sarathy, Suraj Bansal, Andy Zeng, Fieke Hoff, Steven Kornblau, John Dick, Johann Hitzler, Aaron Schimmer
Journal: Blood
Blood (2025) 146 (Supplement 1): 1452.
https://doi.org/10.1182/blood-2025-1452
Published: 2025
Journal Articles

Lipid uptake via FATP2 enhances CAR-t therapy resistance in B-cell acute lymphoblastic leukemia

Free
Clarissa Garcia, Kaylyn Lyons, Julian Grandvallet Contreras, Tian Liu, Alexis Donnelly, Amanda Novak, Amy Argabright, Colin Anderson, Abby Grier, Sabrina Smith, Joshua Michlin, Jesutomisin Olusoji, Railey Mikeska, Xin Zhou, Huimin Geng, Jeremy Rahkola, Hiten Patel, Jeffrey Jacot, Markus Müschen, Angelo D'Alessandro, John Dick, Ilaria Iacobucci, Charles Mullighan, Julie Reisz Haines, Tzu Phang, M. Eric Kohler, Matthew Witkowski
Journal: Blood
Blood (2025) 146 (Supplement 1): 325.
https://doi.org/10.1182/blood-2025-325
Published: 2025
Journal Articles

Decoding the role of inflammatory signaling in shaping HSC heterogeneity and engraftment in gene therapy-treated β-thalassemia pediatric patients

Free
Maria Rosa Lidonnici, Giulia Chianella, Nicole Mende, Hugo Bastos, Matteo Barcella, Andy Zeng, Sayyam Shah, Samantha Scaramuzza, Claudia Rossi, Ivan Merelli, Andrea Calabria, Eugenio Montini, Fabio Ciceri, Alessandro Aiuti, Sarah Marktel, John Dick, Stephanie Xie, Elisa Laurenti, Giuliana Ferrari
Journal: Blood
Blood (2025) 146 (Supplement 1): 4309.
https://doi.org/10.1182/blood-2025-4309
Published: 2025
Journal Articles

Ectopic BCL11B disrupts the activity of early hematopoietic transcription factors to skew lineage commitment

Free
Lindsey Montefiori, Huimei Wei, Wojciech Rosikiewicz, Eric Lechman, Gordon Wong, Chun Shik Park, Beisi Xu, Nicole Michmerhuizen, Pooja Singh, Trevor Cunningham, Ilaria Iacobucci, John Dick, Charles Mullighan
Journal: Blood
Blood (2025) 146 (Supplement 1): 3230.
https://doi.org/10.1182/blood-2025-3230
Published: 2025