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Grace Egan
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Journal Articles

The Exportin, CSE1L, Regulates Ribosome Biogenesis and Is a Selective Dependency in Childhood and Young Adult Acute Myeloid Leukemia

Grace Egan, Amit Kumar, Veronique Voisin, Rose Hurren, Ali Chegini, Dakai Ling, Geethu Emily Thomas, Youngran Yan, Yue Feng, Suraj Bansal, Andy G.X. Zeng, Andrea Arruda, John Edgar Dick, Gary D Bader, Mark D. Minden, Aaron D Schimmer
Journal: Blood
Blood (2024) 144 (Supplement 1): 2724.
https://doi.org/10.1182/blood-2024-200148
Published: 2024
Journal Articles

XPO2 Is Essential for a Subset of AML Cells and Is a Biomarker for Poor Response and Survival in Pediatric and AYA AML

Grace Egan, Geethu Emily Thomas, Rose Hurren, Suraj Bansal, Andy G.X. Zeng, Chaitra Sarathy, Dilshad H. Khan, Yongran Yan, Yue Feng, Jonathan St-Germain, Brian Raught, John E. Dick, Aaron D. Schimmer
Journal: Blood
Blood (2023) 142 (Supplement 1): 5681.
https://doi.org/10.1182/blood-2023-180968
Published: 2023
Journal Articles

The Exportin, XPO2, Is a Novel Therapeutic Target in Pediatric, Adolescent and Young Adult AML

Grace Egan, Rose Hurren, Chaitra Sarathy, Geethu Emily Thomas, Dilshad H. Khan, Yongran Yan, Yue Feng, Brandon Brown, Steven M. Kornblau, Aaron D. Schimmer
Journal: Blood
Blood (2022) 140 (Supplement 1): 11504–11505.
https://doi.org/10.1182/blood-2022-157322
Published: 2022
Journal Articles

The Metabolic Enzyme Hexokinase 2 Localizes to the Nucleus in AML and Normal Hematopoietic Stem/Progenitor Cells to Maintain Stemness

Geethu Emily Thomas, PhDMSc,BSc, Grace Egan, MD, Laura Garcia Prat, PhD BSc, MSc, Botham Aaron, Veronique Voisin, PhD, Elias Orouji, Jordan M Chin, Boaz Nachmias, MDPhD, Kerstin B Kaufmann, PhD, Fieke W Hoff, BSc, Neil Maclean, Rose Hurren, BSc, Xiaoming Wang, Marcela Gronda, MSc, Andrea Arruda, MSc, Mark D. Minden, Gary D Bader, Steven M. Kornblau, MD, John E. Dick, PhD FRS, Aaron D Schimmer, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1–2.
https://doi.org/10.1182/blood-2020-135858
Published: 2020
Journal Articles

Leukemia Stem Cells Demonstrate Increased DNA Damage Repair and Chemoresistance in Acute Myeloid Leukemia

Grace Egan, MD, Geethu Emily Thomas, PhDMSc,BSc, Parasvi Patel, BSc (Hons), Rose Hurren, BSc, Neil MacLean, Razq Hakem, PhD, Aaron D Schimmer, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 2.
https://doi.org/10.1182/blood-2020-136076
Published: 2020
Journal Articles

The Metabolic Enzyme Hexokinase 2 Localizes to the Nucleus in AML and Normal Hematopoietic Stem/Progenitor Cells to Maintain Stemness

Geethu Emily Thomas, PhDMSc,BSc, Grace Egan, MD, Laura Garcia Prat, Boaz Nachmias, MD PhD, Jordan M Chin, Fieke W Hoff, BSc, Kerstin Kaufmann, PhD, Rose Hurren, BSc, Marcela Gronda, MSc, Neil MacLean, Xiaoming Wang, Veronique Voisin, PhD, Aaron Botham, Andrea Arruda, Mark D. Minden, MD PhD, Gary D Bader, Steven M. Kornblau, MD, John E. Dick, PhD, Aaron D Schimmer, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2532.
https://doi.org/10.1182/blood-2019-123121
Published: 2019