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M. Eric Kohler
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Journal Articles

Inhibiting Free Fatty Acid Transport to Improve CAR-T Cell Therapy of Relapsed B-Cell Acute Lymphoblastic Leukemia

Clarissa Garcia, Kaylyn Lyons, Tian Liu, Ilaria Iacobucci, Amanda Novak, Amy Argabright, Alexis Donnelly, Julian Grandvallet Contreras, Huimin Geng, Sabrina Smith, Xin Zhou, Markus Müschen, John Edgar Dick, Julie R Haines, Angelo D'Alessandro, Charles G. Mullighan, Tzu Phang, M. Eric Kohler, Matthew Witkowski
Journal: Blood
Blood (2024) 144 (Supplement 1): 1446.
https://doi.org/10.1182/blood-2024-201015
Published: 2024
Journal Articles

Autologous CD33CART for Children and Adolescents/Young Adults with Relapsed/Refractory AML: Phase 1/2 Clinical Trial Correlative Biology Analyses Demonstrate Potent in Vitro , In Vivo , and Ex Vivo Anti-Leukemia Activity

Tommaso Balestra, Camilo Arenas Merizalde, Robert K Chen, John Roach, Brian Bowser, Rachelle Salomon, Anthony Welch, Bonnie Yates, Kristin Schaller, Michael R Verneris, Susanne H.C. Baumeister, Emily M. Hsieh, M. Eric Kohler, Katherine Tarlock, Steven M. Devine, Richard Aplenc, Nirali N. Shah, Terry J Fry, Sarah K. Tasian
Journal: Blood
Blood (2024) 144 (Supplement 1): 369.
https://doi.org/10.1182/blood-2024-211517
Published: 2024
Journal Articles

Validation of a Digital Polymerase Chain Reaction Assay to Quantify Chimeric Antigen Receptor-Positive T-Cells Relative to Total T-Cells

Lindsey A. Murphy, Laura Sedivy, M. Eric Kohler, Kimberly Jordan, Jill Slansky, Michael Yarnell, Terry J Fry, Amanda Winters
Journal: Blood
Blood (2024) 144 (Supplement 1): 2219.
https://doi.org/10.1182/blood-2024-208786
Published: 2024
Journal Articles

CD64 CAR-T Therapy Targets Venetoclax-Resistant Monocytic Acute Myeloid Leukemia

Haley M. Simpson, Amanda Novak, Catherine Danis, Michael Yarnell, Phoebe Duong, Brett M Stevens, Craig T Jordan, M. Eric Kohler
Journal: Blood
Blood (2024) 144 (Supplement 1): 3416.
https://doi.org/10.1182/blood-2024-205683
Published: 2024
Journal Articles

Preliminary Safety and Tolerability of CD19x22 CAR-T Cell Therapy in Adolescent and Adult Patients with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

Manali K. Kamdar, Bradley M. Haverkos, Alexander W. Rankin, Cheri Adams, Michael R Verneris, Andrew Roth, Kimberly Jordan, Navin R. Pinto, M. Eric Kohler, Angela Ohm, Terry J Fry
Journal: Blood
Blood (2024) 144 (Supplement 1): 4510.
https://doi.org/10.1182/blood-2024-210123
Published: 2024
Journal Articles

Developing a Pediatric-Relevant Murine MLL-r B-ALL Model to Study Factors Involved in Lineage Switching

Wenjuan Liao, Tian Liu, Julian Grandvallet Contreras, Lynn Heltemes Harris, Tzu Phang, Michael A. Farrar, M. Eric Kohler, Terry J Fry, Patricia Ernst
Journal: Blood
Blood (2024) 144 (Supplement 1): 4129.
https://doi.org/10.1182/blood-2024-208932
Published: 2024
Journal Articles

A Novel CD64 CAR-T Therapy for the Treatment of Monocytic Acute Myeloid Leukemia

Haley M. Simpson, Brett M Stevens, Craig T. Jordan, M. Eric Kohler
Journal: Blood
Blood (2023) 142 (Supplement 1): 2064.
https://doi.org/10.1182/blood-2023-182123
Published: 2023
Journal Articles

Restoration of LAT Signaling in CD33-Directed CAR T Cells Improves Potency and Persistence Against Acute Myeloid Leukemia

Catherine Danis, Lillie Leach, Amanda Novak, M. Eric Kohler
Journal: Blood
Blood (2023) 142 (Supplement 1): 468.
https://doi.org/10.1182/blood-2023-186866
Published: 2023
Journal Articles

T-Bet Overexpression Increases 4-1BB-Costimulated CAR T Cell Potency

Jennifer Cimons, Kole R. Degolier, Michael Yarnell, M. Eric Kohler, Terry J. Fry
Journal: Blood
Blood (2023) 142 (Supplement 1): 4816.
https://doi.org/10.1182/blood-2023-186902
Published: 2023
Journal Articles

CD33 CAR T-Cells (CD33CART) for Children and Young Adults with Relapsed/Refractory AML: Dose-Escalation Results from a Phase I/II Multicenter Trial

Nirali N. Shah, Sarah K. Tasian, M. Eric Kohler, Emily M. Hsieh, Susanne H.C. Baumeister, Corinne Summers, Haneen Shalabi, Jessica A. Pollard, Bonnie Yates, Ruta Brazauskas, Eric Ndifon, Constance M. Yuan, Hao-Wei Wang, Hati K Kobusingye, Kayla Christianson, Allison A Weiss, Erin Leckrone, Bronwen E. Shaw, Jeffery J. Auletta, Hemalatha G. Rangarajan, John Roach, Julie Blake, Dennis Michiel, Brian Bowser, Sheryl Ruppel, George Mitra, Anthony Welch, Jason Yovandich, Rachelle Salomon, Leslie Kean, Katherine Tarlock, Michael A. Pulsipher, Michael R Verneris, Larisa Broglie, Terry J. Fry, Steven M. Devine, Richard Aplenc
Journal: Blood
Blood (2023) 142 (Supplement 1): 771.
https://doi.org/10.1182/blood-2023-179667
Published: 2023
Journal Articles

Runx2 Overexpression Enhances Potency and Counteracts Exhaustion in CD8+ CAR T Cells

Kole R. Degolier, Etienne Danis, Jennifer Cimons, Michael Yarnell, Ross Kedl, M. Eric Kohler, James Scott-Browne, Terry J. Fry
Journal: Blood
Blood (2023) 142 (Supplement 1): 2082.
https://doi.org/10.1182/blood-2023-186898
Published: 2023
Journal Articles

Enhancing the Antigen-Sensitivity of the CD22 CAR through Modulation of the Affinity and Linker-Length of the Single-Chain Fragment Variable

M. Eric Kohler, MD PhD, Zachary Walsh, Kole Degolier, Terry J. Fry, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 41–42.
https://doi.org/10.1182/blood-2020-143372
Published: 2020
Journal Articles

Using erythrocyte tools to enhance CAR T cells

M. Eric Kohler, Terry J. Fry
Journal: Blood
Blood (2020) 135 (9): 595–596.
https://doi.org/10.1182/blood.2019003944
Published: 2020
Journal Articles

Murine pre–B-cell ALL induces T-cell dysfunction not fully reversed by introduction of a chimeric antigen receptor

Haiying Qin, Kazusa Ishii, Sang Nguyen, Paul P. Su, Chad R. Burk, Bong-Hyun Kim, Brynn B. Duncan, Samikasha Tarun, Nirali N. Shah, M. Eric Kohler, Terry J. Fry
Journal: Blood
Blood (2018) 132 (18): 1899–1910.
https://doi.org/10.1182/blood-2017-12-815548
Published: 2018
Includes: Supplemental data