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Journal Articles

Recruitment of MLL1 Complex Is Essential for SETBP1 to Induce Myeloid Transformation

Nhu Nguyen, Kristbjorn Orri Gudmundsson, Anthony R. Soltis, Kevin Oakley, Yufen Han, Jaroslaw P. Maciejewski, Patricia Ernst, Clifton L. Dalgard, Yang Du
Journal: Blood
Blood (2021) 138 (Supplement 1): 1147.
https://doi.org/10.1182/blood-2021-152825
Published: 2021
Journal Articles

Rationale for Targeting BCL6 in MLL-Rearranged B-ALL

Lai N Chan, PhD, Christian Hurtz, PhD, Huimin Geng, PhD, Erica Ballabio, Gang Xiao, PhD, Gauri Deb, MS, PhD, Haytham Khoury, MD PhD, Scott A. Armstrong, MD PhD, Patricia Ernst, PhD, Ari Melnick, MD, Tom Arthur Milne, PhD, Markus Müschen, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1239.
https://doi.org/10.1182/blood-2019-131565
Published: 2019
Journal Articles

Gain of Function MLL1 Model Systems Distinguish Hematopoietic from Leukemogenic Pathways

Weiwei Yang, David Bryder, PhD, Patricia Ernst, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2435.
https://doi.org/10.1182/blood.V130.Suppl_1.2435.2435
Published: 2017
Journal Articles

Oncogenic Feedback Activation Between BCL6 and MLL Promotes Malignant Transformation in MLL -RearrangedAcute Lymphoblastic Leukemia

Christian Hurtz, PhD, Lai N Chan, PhD, Erica Ballabio, MD, Cheryl L. Willman, William L. Carroll, MD, Scott A. Armstrong, MD PhD, Patricia Ernst, PhD, Ari Melnick, MD, Thomas Milne, PhD, Markus Müschen, MD PhD
Journal: Blood
Blood (2016) 128 (22): 907.
https://doi.org/10.1182/blood.V128.22.907.907
Published: 2016
Journal Articles

The Role of MLL1 and MLL2 in MLL Fusion Oncoprotein-Initiated Leukemia

Patricia Ernst, PhD, Konstantinos Anastassiadis, PhD, Andrea Kranz, PhD, A. Francis Stewart, PhD, Kathrin Arndt, PhD, Claudia Waskow, PhD, Akihiko Yokoyama, PhD, Kenneth Jones, PhD, Tobias Neff, MD, Yufei Chen
Journal: Blood
Blood (2016) 128 (22): 573.
https://doi.org/10.1182/blood.V128.22.573.573
Published: 2016
Journal Articles

Meningeoma-1 Cooperates with MLL and DOT1L to Induce Leukemia

Simone Riedel, PhD, Jessica Haladyna, BA, Brett Stevens, Craig T Jordan, PhD, Daniel Pollyea, MD MS, Scott A. Armstrong, MD PhD, Qi Wei, PhD, Patricia Ernst, PhD, Tobias Neff, MD, Kathrin M Bernt, MD
Journal: Blood
Blood (2015) 126 (23): 2428.
https://doi.org/10.1182/blood.V126.23.2428.2428
Published: 2015
Journal Articles

Distinct pathways regulated by menin and by MLL1 in hematopoietic stem cells and developing B cells

Bin E. Li, Tao Gan, Matthew Meyerson, Terence H. Rabbitts, Patricia Ernst
Journal: Blood
Blood (2013) 122 (12): 2039–2046.
https://doi.org/10.1182/blood-2013-03-486647
Published: 2013
Includes: Supplemental data
Journal Articles

Coordinating Self-Renewal and Proliferation via MLL1-HOX Pathways and Beyond

Patricia Ernst, PhD, Erika L. Artinger, Bibhu P. Mishra, Kristin M. Zaffuto, Bin E. Li, Yufei Chen
Journal: Blood
Blood (2012) 120 (21): SCI-28.
https://doi.org/10.1182/blood.V120.21.SCI-28.SCI-28
Published: 2012
Journal Articles

Zebrafish Mll Depletion Model Phenocopies Mammalian Mll Depletion and Implicates MLL as Master Regulator of Novel Developmental Hematopoietic Targets.

Blaine W. Robinson, PhD, Yuanquan Song, PhD, Giuseppe Germano, PhD, Patricia Ernst, PhD, Joshua Abrams, Marion Scott, Amy Kugath, Marybeth Helfrich, J. Oriol Sunyer, PhD, Jennifer Rhodes, PhD, Rita Balice-Gordon, PhD, Carolyn A. Felix, MD
Journal: Blood
Blood (2009) 114 (22): 3655.
https://doi.org/10.1182/blood.V114.22.3655.3655
Published: 2009
Journal Articles

Cdx4 Upregulates Hox Gene Expression and Generates Acute Myeloid Leukemia Alone and in Cooperation with Meis1a in a Murine Model.

Dimple Bansal, PhD, Claudia Scholl, M.D, Stefan Frohling, M.D, Elizabeth Mcdowell, B.S, Benjamin H. Lee, M.D, Ph.D., Konstanze Dohner, M.D., Patricia Ernst, Ph.D., Alan J. Davidson, Ph.D., George Q. Daley, M.D., Ph.D, Leonard I. Zon, M.D., D. Gary Gilliland, M. D, Ph. D, Brian J. Huntly, M. D, Ph.D
Journal: Blood
Blood (2006) 108 (11): 10.
https://doi.org/10.1182/blood.V108.11.10.10
Published: 2006
Journal Articles

Derivation of Hematopoietic Stem Cells from Embryonic Stem Cells.

Yuan Wang, Ph.D, Frank Yates, Ph.D, Eugenia Dikovskaia, M.D., Patricia Ernst, Ph.D, Alan J. Davidson, Ph.D, Leonard I. Zon, M.D., George Q. Daley, M.D., Ph.D
Journal: Blood
Blood (2004) 104 (11): 223.
https://doi.org/10.1182/blood.V104.11.223.223
Published: 2004