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Journal Articles

Systematic Evaluation of AML-Associated Antigens Identifies Novel Anti-U5 snRNP200 Therapeutic Antibodies for the Treatment of AML

Katherine Knorr, Caroline Erickson, Eric Wang, Jahan Rahman, Xiaoli Mi, Sydney Lu, Nina Fox, Alex Penson, Simon Hogg, Robert Stanley, Daichi Inoue, David Knorr, Jeffrey Ravetch, Omar Abdel-Wahab

Blood (2022) 140 (Supplement 1): 2247–2248.

https://doi.org/10.1182/blood-2022-158445

Published: 2022

Journal Articles

Aberrant EVI1 splicing contributes to EVI1 -rearranged leukemia

Blood (2022) 140 (8): 875–888.

https://doi.org/10.1182/blood.2021015325

Published: 2022

Includes: Supplemental data

Journal Articles

Impaired RAS Proteolysis Drives Clonal Hematopoietic Transformation

Blood (2021) 138 (Supplement 1): 356.

https://doi.org/10.1182/blood-2021-147026

Published: 2021

Journal Articles

ZRSR2 Mutation Induced Minor Intron Retention Drives MDS and Diverse Cancer Predisposition Via Aberrant Splicing of LZTR1

Blood (2020) 136 (Supplement 1): 10–11.

https://doi.org/10.1182/blood-2020-136445

Published: 2020

Journal Articles

Impaired Osteoblastic Differentiation of MSCs Suppresses Normal Hematopoiesis in MDS

Blood (2020) 136 (Supplement 1): 17–18.

https://doi.org/10.1182/blood-2020-142284

Published: 2020

Journal Articles

HHEX promotes myeloid transformation in cooperation with mutant ASXL1

Blood (2020) 136 (14): 1670–1684.

https://doi.org/10.1182/blood.2019004613

Published: 2020

Includes: Supplemental data

Journal Articles

Spliceosomal Disruption of the Non-Canonical SWI/SNF Chromatin Remodeling Complex in SF3B1 Mutant Leukemias

Daichi Inoue, MD PhD, Chew Guo-Liang, Bo Liu, PhD, Stanley C Lee, PhD, Brittany C Michel, Joey Pangallo, B.S., Andrew R D'Avino, Khrystyna North, Lillian E Bitner, BSc, Muran Xiao, Susumu Kobayashi, Akihide Yoshimi, MD PhD, Hana Cho, MSc, Sydney X Lu, MD PhD, Justin Taylor, MD, Cigall Kadoch, PhD, Robert K. Bradley, PhD, Omar Abdel-Wahab, MD

Blood (2019) 134 (Supplement_1): 637.

https://doi.org/10.1182/blood-2019-124616

Published: 2019

Journal Articles

Homeobox Transcription Factor Hhex Promotes Myeloid Leukemia in Cooperation with Mutant ASXL1

Blood (2019) 134 (Supplement_1): 2525.

https://doi.org/10.1182/blood-2019-126663

Published: 2019

Journal Articles

Leukemogenic Functions of Mutant ASXL1 Are Regulated By CDK-Mediated Phosphorylation

Shuhei Asada, MD PhD, Susumu Goyama, MD PhD, Reina Takeda, MD, Keita Yamamoto, MD, Hiroko Kozuka-Hata, PhD, Masaaki Oyama, PhD, Daichi Inoue, MD PhD, Hiroaki Honda, MD PhD, Toshio Kitamura, MD PhD

Blood (2019) 134 (Supplement_1): 731.

https://doi.org/10.1182/blood-2019-125959

Published: 2019

Journal Articles

Mutant ASXL1 Promotes Expansion of the Phenotypic Hematopoietic Stem Cell Compartment

Takeshi Fujino, MD, Susumu Goyama, MD PhD, Yuki Sugiura, PhD, Daichi Inoue, MD PhD, Satoshi Yamasaki, PhD, Akiko Matsumoto, Naru Sato, MD, Hironobu Morinaga, PhD, Shiori Shikata, Tomofusa Fukuyama, MD PhD, Yosuke Tanaka, PhD, Shuhei Asada, MD PhD, Tsuyoshi Fukushima, MD PhD, Hiroaki Honda, MD PhD, Emi K Nishimura, MD PhD, Tatsuhiro Shibata, MD PhD, Makoto Suematsu, MD PhD, Toshio Kitamura, MD PhD

Blood (2019) 134 (Supplement_1): 821.

https://doi.org/10.1182/blood-2019-127904

Published: 2019

Journal Articles

Aberrant RNA Splicing Contributes to the Pathogenesis of EVI-Rearranged Myeloid Leukemias

Daichi Inoue, MD PhD, Stanley C Lee, PhD, Akihide Yoshimi, MD PhD, Justin Taylor, MD, Lillian E Bitner, BSc, Atsushi Tanaka, MD, Yasutaka Hayashi, MD PhD, Hana Cho, MSc, Chie Fukui, Ruth Saganty, Alexander V Penson, PhD, Omar Abdel-Wahab, MD

Blood (2019) 134 (Supplement_1): 917.

https://doi.org/10.1182/blood-2019-124722

Published: 2019

Journal Articles

Mutant ASXL1 Cooperates with BAP1 to Promote Myeloid Leukemogenesis

Shuhei Asada, MD, Susumu Goyama, MD PhD, Daichi Inoue, MD PhD, Reina Takeda, MD, Masahito Kawazu, Hiroyuki Mano, MDPhD, Toshio Kitamura, MD PhD

Blood (2017) 130 (Supplement 1): 562.

https://doi.org/10.1182/blood.V130.Suppl_1.562.562

Published: 2017

Journal Articles

Spliceosomal Dysfunction Is a Critical Mediator of IDH2 Mutant Leukemogenesis

Blood (2017) 130 (Supplement 1): 473.

https://doi.org/10.1182/blood.V130.Suppl_1.473.473

Published: 2017

Journal Articles

Synthetic Lethal Interactions of MDS-Associated Spliceosomal Gene Mutations Identifies the Basis for Their Mutual Exclusivity

Stanley Chun-Wei Lee, PhD, Khrystyna Dilai, Esther A. Obeng, MDPhD, Eunhee Kim, PhD, Jean-Baptiste Micol, MD PhD, Akihide Yoshimi, MD PhD, Christophe Willekens, MD, Daichi Inoue, Véronique Saada, PharmD, Hana Cho, Young Rock Chung, MS, James Palacino, PhD, Michael Seiler, PhD, Silvia Buonamici, PhD, Peter Smith, Benjamin L. Ebert, MD PhD, Robert Bradley, PhD, Omar Abdel-Wahab, MD

Blood (2016) 128 (22): 961.

https://doi.org/10.1182/blood.V128.22.961.961

Published: 2016

Journal Articles

A Patient-Derived EZH2 Mutant Induces MDS-like Diseases with Derepressed ABCG2 Expression in Mice

Kimihito Cojin Kawabata, MD PhD, Daichi Inoue, MD PhD, Jiro Kitaura, MD PhD, Yuka Harada, MD PhD, Susumu Goyama, MD PhD, Hironori Harada, MD PhD, Hiroyuki Aburatani, MD PhD, Toshio Kitamura, MD PhD

Blood (2015) 126 (23): 4116.

https://doi.org/10.1182/blood.V126.23.4116.4116

Published: 2015

Journal Articles

SETBP1 Mutations Drive Leukemic Transformation in ASXL1 -Mutated MDS

Daichi Inoue, MD PhD, Hirotaka Matsui, MD PhD, Hsin-An Hou, MD PhD, Wen-Chien Chou, MD PhD, Akiko Nagamachi, PhD, Jiro Kitaura, MD PhD, Kimihito Cojin Kawabata, MD PhD, Katsuhiro Togami, MD PhD, Reina Nagase, Sayuri Horikawa, Makoto Saika, MD, Jean-Baptiste Micol, MD, Yasutaka Hayashi, MD, Yuka Harada, MD PhD, Hironori Harada, MD PhD, Hwei-Fang Tien, MD PhD, Omar Abdel-Wahab, MD, Toshio Kitamura, MD PhD

Blood (2014) 124 (21): 525.

https://doi.org/10.1182/blood.V124.21.525.525

Published: 2014

Journal Articles

Hes1 promotes blast crisis in chronic myelogenous leukemia through MMP-9 upregulation in leukemic cells

Blood (2014) 123 (25): 3932–3942.

https://doi.org/10.1182/blood-2013-01-476747

Published: 2014

Includes: Supplemental data

Journal Articles

C-Terminal-Truncating ASXL1 Mutations Induce MDS Via Inhibition Of PRC2

Daichi Inoue, MD, Jiro Kitaura, Katsuhiro Togami, Koutarou Nishimura, Yutaka Enomoto, Tomoyuki Uchida, Yuki Kagiyama, PhD, Kimihito Cojin Kawabata, Fumio Nakahara, Toshihiko Oki, Hironori Harada, Takahiro Ochiya, PhD, Hiroyuki Aburatani, M.D., Ph.D., Hiroshi Kimura, Felicitas Thol, MD, Michael Heuser, MD, Ross L. Levine, MD, Omar Abdel-Wahab, MD, Toshio Kitamura, MD, PhD

Blood (2013) 122 (21): 471.

https://doi.org/10.1182/blood.V122.21.471.471

Published: 2013

Journal Articles

RUNX1/AML1 mutant collaborates with BMI1 overexpression in the development of human and murine myelodysplastic syndromes

Yuka Harada, Daichi Inoue, Ye Ding, Jun Imagawa, Noriko Doki, Hirotaka Matsui, Takashi Yahata, Hiromichi Matsushita, Kiyoshi Ando, Goro Sashida, Atsushi Iwama, Toshio Kitamura, Hironori Harada

Blood (2013) 121 (17): 3434–3446.

https://doi.org/10.1182/blood-2012-06-434423

Published: 2013

Includes: Supplemental data

Journal Articles

RUNX1/AML1 Mutants Collaborate with BMI1 in the Development of Myelodysplastic Syndromes (MDS) / Acute Myeloid Leukemia (AML) in a Mouse BMT Model.

Hironori Harada, MD, PhD, Daichi Inoue, MD, Noriko Doki, MD, Ye Ding, MD, PhD, Yuka Harada, MD, PhD, Toshio Kitamura, MD, PhD

Blood (2012) 120 (21): 2820.

https://doi.org/10.1182/blood.V120.21.2820.2820

Published: 2012

NARROW

Systematic Evaluation of AML-Associated Antigens Identifies Novel Anti-U5 snRNP200 Therapeutic Antibodies for the Treatment of AML

Aberrant EVI1 splicing contributes to EVI1 -rearranged leukemia

Impaired RAS Proteolysis Drives Clonal Hematopoietic Transformation

ZRSR2 Mutation Induced Minor Intron Retention Drives MDS and Diverse Cancer Predisposition Via Aberrant Splicing of LZTR1

Impaired Osteoblastic Differentiation of MSCs Suppresses Normal Hematopoiesis in MDS

HHEX promotes myeloid transformation in cooperation with mutant ASXL1

Spliceosomal Disruption of the Non-Canonical SWI/SNF Chromatin Remodeling Complex in SF3B1 Mutant Leukemias

Homeobox Transcription Factor Hhex Promotes Myeloid Leukemia in Cooperation with Mutant ASXL1

Leukemogenic Functions of Mutant ASXL1 Are Regulated By CDK-Mediated Phosphorylation

Mutant ASXL1 Promotes Expansion of the Phenotypic Hematopoietic Stem Cell Compartment

Aberrant RNA Splicing Contributes to the Pathogenesis of EVI-Rearranged Myeloid Leukemias

Mutant ASXL1 Cooperates with BAP1 to Promote Myeloid Leukemogenesis

Spliceosomal Dysfunction Is a Critical Mediator of IDH2 Mutant Leukemogenesis

Synthetic Lethal Interactions of MDS-Associated Spliceosomal Gene Mutations Identifies the Basis for Their Mutual Exclusivity

A Patient-Derived EZH2 Mutant Induces MDS-like Diseases with Derepressed ABCG2 Expression in Mice

SETBP1 Mutations Drive Leukemic Transformation in ASXL1 -Mutated MDS

Hes1 promotes blast crisis in chronic myelogenous leukemia through MMP-9 upregulation in leukemic cells

C-Terminal-Truncating ASXL1 Mutations Induce MDS Via Inhibition Of PRC2

RUNX1/AML1 mutant collaborates with BMI1 overexpression in the development of human and murine myelodysplastic syndromes

RUNX1/AML1 Mutants Collaborate with BMI1 in the Development of Myelodysplastic Syndromes (MDS) / Acute Myeloid Leukemia (AML) in a Mouse BMT Model.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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