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Stanley C. Lee
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Journal Articles

Multi-Omics Analysis Reveals That TET2 Loss Epigenetically Primes Monocytes for Inflammatory Responses Via AP-1 Signaling

Matthew Jenkins, Yunli Chu, Sajesan Aryal, Xinyue Zhou, Kirsten Dickerson, Rebecca Dubin, Chad R Potts, Valeriya Kuznetsova, Alana Franceski, Paran Goel, Stanley C Lee, Rui Lu, Robert Welner, P. Brent Ferrell, Jr.
Journal: Blood
Blood (2023) 142 (Supplement 1): 4061.
https://doi.org/10.1182/blood-2023-182278
Published: 2023
Journal Articles

Aberrant EVI1 splicing contributes to EVI1 -rearranged leukemia

Atsushi Tanaka, Taizo A. Nakano, Masaki Nomura, Hiromi Yamazaki, Jan P. Bewersdorf, Roger Mulet-Lazaro, Simon Hogg, Bo Liu, Alex Penson, Akihiko Yokoyama, Weijia Zang, Marije Havermans, Miho Koizumi, Yasutaka Hayashi, Hana Cho, Akinori Kanai, Stanley C. Lee, Muran Xiao, Yui Koike, Yifan Zhang, Miki Fukumoto, Yumi Aoyama, Tsuyoshi Konuma, Hiroyoshi Kunimoto, Toshiya Inaba, Hideaki Nakajima, Hiroaki Honda, Hiroshi Kawamoto, Ruud Delwel, Omar Abdel-Wahab, Daichi Inoue
Journal: Blood
Blood (2022) 140 (8): 875–888.
https://doi.org/10.1182/blood.2021015325
Published: 2022
Includes: Supplemental data
Journal Articles

Spliceosome Mutant Myeloid Malignancies Are Preferentially Sensitive to PARP Inhibition

Dang Hai Nguyen, Zhiyan Silvia Liu, Sayantani Sinha, Maxwell Bannister, Erica Arriaga-Gomez, Axia Song, Dawei Zong, Victor Corral, Cassandra Leibson, Sumit Rai, Timothy A. Graubert, Stanley C Lee
Journal: Blood
Blood (2021) 138 (Supplement 1): 322.
https://doi.org/10.1182/blood-2021-149688
Published: 2021
Journal Articles

Spliceosomal Disruption of the Non-Canonical SWI/SNF Chromatin Remodeling Complex in SF3B1 Mutant Leukemias

Daichi Inoue, MD PhD, Chew Guo-Liang, Bo Liu, PhD, Stanley C Lee, PhD, Brittany C Michel, Joey Pangallo, B.S., Andrew R D'Avino, Khrystyna North, Lillian E Bitner, BSc, Muran Xiao, Susumu Kobayashi, Akihide Yoshimi, MD PhD, Hana Cho, MSc, Sydney X Lu, MD PhD, Justin Taylor, MD, Cigall Kadoch, PhD, Robert K. Bradley, PhD, Omar Abdel-Wahab, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 637.
https://doi.org/10.1182/blood-2019-124616
Published: 2019
Journal Articles

Aberrant RNA Splicing Contributes to the Pathogenesis of EVI-Rearranged Myeloid Leukemias

Daichi Inoue, MD PhD, Stanley C Lee, PhD, Akihide Yoshimi, MD PhD, Justin Taylor, MD, Lillian E Bitner, BSc, Atsushi Tanaka, MD, Yasutaka Hayashi, MD PhD, Hana Cho, MSc, Chie Fukui, Ruth Saganty, Alexander V Penson, PhD, Omar Abdel-Wahab, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 917.
https://doi.org/10.1182/blood-2019-124722
Published: 2019
Journal Articles

Mutations in the RNA Splicing Factor SF3B1 Promote Transformation through MYC Stabilization

Akihide Yoshimi, MD, Zhaoqi Liu, PhD, Wang Jiguang, Hana Cho, MSc, Stanley C Lee, PhD, Michelle Ki, BSc, Lillian E Bitner, BSc, Timothy Chu, Anthony R Mato, MD, Peter P. Ruvolo, PhD, Giulia Fabbri, Laura Pasqualucci, MD, Raul Rabadan, PhD, Omar I Abdel-Wahab, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 882.
https://doi.org/10.1182/blood-2018-99-110328
Published: 2018
Journal Articles

Therapeutic Targeting of an RNA Splicing Factor Network for the Treatment of Myeloid Neoplasms

Sydney X. Lu, MD PhD, Eric Wang, Alessandro Pastore, Chen Xufeng, PhD, Jochen Imig, PhD, Stanley C Lee, PhD, Yohana Ghebrechristos, Akihide Yoshimi, MD, Lillian E Bitner, BSc, Michelle Ki, BSc, Andreas Kloetgen, Kuan-Ting Lin, PhD, Raoul Tibes, MD PhD, Adrian R. Krainer, PhD, Taisuke Uehara, Takashi Owa, PhD, Iannis Aifantis, PhD, Omar I Abdel-Wahab, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 427.
https://doi.org/10.1182/blood-2018-99-111430
Published: 2018
Journal Articles

Multimodal Single-Cell Profiling Defines the Epigenetic Determinants of Chronic Lymphocytic Leukemia Evolution

Ronan Chaligne, PhD, Federico Gaiti, PhD, Franco Izzo, PhD, Steven Kothen-Hill, MS, Hongcang Gu, Kevin Huang, BS, Davide Risso, PhD, Rafael Schulman, BS, Ryan M Brand, Stanley C Lee, PhD, Asaf Poran, Kye-Tae Kim, PhD, Alessandro Pastore, Alicia Alonso, Andreas Gnirke, Catherine J. Wu, MD, Omar I Abdel-Wahab, MD, Alexander Meissner, PhD, Dan A. Landau, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1312.
https://doi.org/10.1182/blood-2018-99-115596
Published: 2018
Journal Articles

Dependency of Spliceosomal Mutant MDS on Innate Immune Signaling

Stanley C Lee, PhD, Khrystyna North, Chi-Chao Chen, Eunhee Kim, PhD, Sydney X. Lu, MD PhD, Michelle Ki, BSc, Ralph Garippa, PhD, Scott W Lowe, PhD, Robert K. Bradley, PhD, Omar I Abdel-Wahab, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 937.
https://doi.org/10.1182/blood-2018-99-111552
Published: 2018