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Journal Articles

A Novel Anticancer Quinolone, ( R )-Wac-224 Monotherapy or Combination with Cytarabine/Venetoclax Confers Promising Activities Against Acute Myeloid Leukemia

Tatsuji Mino, Hiroshi Ureshino, Taichi Ueshima, Naoki Kashimoto, Tomonori Yamaguchi, Miyuki Takashima, Yusuke Sanuki, Kazuhito Naka, Toshiya Inaba, Tatsuo Ichinohe

Blood (2023) 142 (Supplement 1): 5775.

https://doi.org/10.1182/blood-2023-175075

Published: 2023

Journal Articles

Mir-106a-5p and Mir-146a-5p Delivered By Tumor-Derived Exosomes Promote the Induction of Myeloid-Derived Suppressor Cells from Normal Peripheral Blood Mononuclear Cells in Multiple Myeloma

Kentaro Mizuhara, Yuji Shimura, Taku Tsukamoto, Akinori Kanai, Saeko Kuwahara-Ota, Junko Yamaguchi, Ayako Muramatsu, Haruya Okamoto, Yoko Katsuragawa-Taminishi, Yuka Kawaji-Kanayama, Reiko Isa, Shinsuke Mizutani, Toshiya Inaba, Junya Kuroda

Blood (2022) 140 (Supplement 1): 9949–9950.

https://doi.org/10.1182/blood-2022-160408

Published: 2022

Journal Articles

Aberrant EVI1 splicing contributes to EVI1 -rearranged leukemia

Blood (2022) 140 (8): 875–888.

https://doi.org/10.1182/blood.2021015325

Published: 2022

Includes: Supplemental data

Journal Articles

UTX maintains the functional integrity of the murine hematopoietic system by globally regulating aging-associated genes

Blood (2021) 137 (7): 908–922.

https://doi.org/10.1182/blood.2019001044

Published: 2021

Includes: Supplemental data

Journal Articles

Association of aberrant ASNS imprinting with asparaginase sensitivity and chromosomal abnormality in childhood BCP-ALL

Blood (2020) 136 (20): 2319–2333.

https://doi.org/10.1182/blood.2019004090

Published: 2020

Includes: Supplemental data

Journal Articles

HHEX promotes myeloid transformation in cooperation with mutant ASXL1

Blood (2020) 136 (14): 1670–1684.

https://doi.org/10.1182/blood.2019004613

Published: 2020

Includes: Supplemental data

Journal Articles

Homeobox Transcription Factor Hhex Promotes Myeloid Leukemia in Cooperation with Mutant ASXL1

Blood (2019) 134 (Supplement_1): 2525.

https://doi.org/10.1182/blood-2019-126663

Published: 2019

Journal Articles

Genome-Wide Analysis of BRD4-Targets Reveals the Therapeutic Relevance of Simultaneous Targeting of BCR Pathway and IKZF-MYC Axis in Mantle Cell Lymphoma

Junya Kuroda, MD PhD, Taku Tsukamoto, MD PhD, Shingo Nakahata, Kazuhiro Morishita, MD PhD, Ryuichi Sato, Akinori Kanai, PhD, Toshiya Inaba, Masakazu Nakano, Kei Tashiro, Masafumi Taniwaki, MD PhD

Blood (2018) 132 (Supplement 1): 4100.

https://doi.org/10.1182/blood-2018-99-109982

Published: 2018

Journal Articles

The enigma of monosomy 7

Toshiya Inaba, Hiroaki Honda, Hirotaka Matsui

Blood (2018) 131 (26): 2891–2898.

https://doi.org/10.1182/blood-2017-12-822262

Published: 2018

Journal Articles

Aberrant Repression of GFI1 Super-Enhancer By LSD1 Plays an Important Role in Leukemia Programs in Acute Myeloid Leukemia

Goichi Tatsumi, MD, Masahiro Kawahara, MD PhD, Akinori Kanai, PhD, Hirotaka Matsui, MD PhD, Ryusuke Yamamoto, MD, Masakatsu Hishizawa, MD PhD, Toshiya Inaba, MD PhD, Takayoshi Suzuki, PhD, Akira Andoh, MD PhD, Akifumi Kondo Takaori, MD PhD

Blood (2017) 130 (Supplement 1): 3797.

https://doi.org/10.1182/blood.V130.Suppl_1.3797.3797

Published: 2017

Journal Articles

Acquired expression of Cbl Q367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia

Yuichiro Nakata, Takeshi Ueda, Akiko Nagamachi, Norimasa Yamasaki, Ken-ichiro Ikeda, Yasuyuki Sera, Keiyo Takubo, Akinori Kanai, Hideaki Oda, Masashi Sanada, Seishi Ogawa, Kohichiro Tsuji, Yasuhiro Ebihara, Linda Wolff, Zen-ichiro Honda, Toshio Suda, Toshiya Inaba, Hiroaki Honda

Blood (2017) 129 (15): 2148–2160.

https://doi.org/10.1182/blood-2016-06-724658

Published: 2017

Includes: Supplemental data

Journal Articles

JMJD3 Plays Essential Roles in the Maintenance of Hematopoietic Stem Cells and Leukemic Stem Cells through the Regulation of p16 INK4a

Yuichiro Nakata, PhD, Norimasa Yamasaki, Takeshi Ueda, MD, PhD, Kenichiro Ikeda, MD, Akiko Nagamachi, PhD, Toshiya Inaba, MD, PhD, Hiroaki Honda, MD, PhD

Blood (2016) 128 (22): 2653.

https://doi.org/10.1182/blood.V128.22.2653.2653

Published: 2016

Journal Articles

Low Miki Expression in Myelodysplastic Syndromes Results in Polynuclear Cell Formation through Decondensation of Chromosomes in Prolonged Prometaphase

Akiko Nagamachi, PhD, Yuko Ozaki, PhD, Hirotaka Matsui, MD PhD, Akinori Kanai, PhD, Toshiya Inaba, MD

Blood (2015) 126 (23): 2845.

https://doi.org/10.1182/blood.V126.23.2845.2845

Published: 2015

Journal Articles

Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2

Takeshi Ueda, Akiko Nagamachi, Keiyo Takubo, Norimasa Yamasaki, Hirotaka Matsui, Akinori Kanai, Yuichiro Nakata, Kenichiro Ikeda, Takaaki Konuma, Hideaki Oda, Linda Wolff, Zen-ichiro Honda, Xudong Wu, Kristian Helin, Atsushi Iwama, Toshio Suda, Toshiya Inaba, Hiroaki Honda

Blood (2015) 125 (22): 3437–3446.

https://doi.org/10.1182/blood-2014-03-562694

Published: 2015

Includes: Supplemental data

Journal Articles

Generation and Analysis of a Novel Mouse Model for Chronic Myelomonocytic Leukemia (CMML) with Acquired Expression of c-CBL Q367P

Yuichiro Nakata, Takeshi Ueda, MD PhD, Akiko Nagamachi, PhD, Linda Wolff, PhD, Ogawa Seishi, MD, Toshiya Inaba, MD, Hiroaki Honda, MD PhD

Blood (2014) 124 (21): 4602.

https://doi.org/10.1182/blood.V124.21.4602.4602

Published: 2014

Journal Articles

Haploinsufficiency Of SAMD9L , An Endosome Fusion Facilitator, In Mice Induces The Development Of Myeloid Malignancies Mimicking Human Diseases With Monosomy 7

Hirotaka Matsui, MD, PhD, Akiko Nagamachi, Akinori Kanai, PhD, Yuko Ozaki, Hiroaki Honda, MD, PhD, Toshiya Inaba, MD, PhD

Blood (2013) 122 (21): 227.

https://doi.org/10.1182/blood.V122.21.227.227

Published: 2013

Journal Articles

Identification of Integrin β3 L718P Mutation in a Pedigree with Autosomal Dominant Macrothrombocytopenia

Yoshiyuki Kobayashi, MD, Hirotaka Matsui, MD, Akinori Kanai, PhD, Miyuki Tsumura, MSc, Satoshi Okada, MD, PhD, Mizuka Miki, MD, Kazuhiro Nakamura, MD, PhD, Shinji Kunishima, PhD, Toshiya Inaba, MD, PhD, Masao Kobayashi, MD, PhD

Blood (2012) 120 (21): 1081.

https://doi.org/10.1182/blood.V120.21.1081.1081

Published: 2012

Journal Articles

SLIT1 Mutation in Patients with Acquired Aplastic Anemia: Its Relevance in Immune Pathophysiology

Chizuru Saito, MD, Kohei Hosokawa, MD, Takamasa Katagiri, PhD, Akinori Kanai, PhD, Hirotaka Matsui, MD, Toshiya Inaba, MD, PhD, Masafumi Taniwaki, MD, PhD, Hirohito Yamazaki, MD, PhD, Shinji Nakao, MD, PhD

Blood (2012) 120 (21): 645.

https://doi.org/10.1182/blood.V120.21.645.645

Published: 2012

Journal Articles

Abnormal Mitosis Due to Impairment of Centrosome Maturation by the Deletion of Candidate 7q- Responsible Genes

Hirotaka Matsui, MD, Yuko Ozaki, Akiko Nagamachi, Toshiya Inaba, MD, PhD

Blood (2012) 120 (21): 1297.

https://doi.org/10.1182/blood.V120.21.1297.1297

Published: 2012

Journal Articles

Samd9L-Deficient Mice Develop Myeloid Malignancies Mimicking Human Diseases with Monosomy 7

Hirotaka Matsui, MD, Akiko Nagamachi, Yuko Ozaki, Hiroya Asou, MD, PhD, Hiroaki Honda, MD, PhD, Toshiya Inaba, MD, PhD

Blood (2011) 118 (21): 869.

https://doi.org/10.1182/blood.V118.21.869.869

Published: 2011

NARROW

A Novel Anticancer Quinolone, ( R )-Wac-224 Monotherapy or Combination with Cytarabine/Venetoclax Confers Promising Activities Against Acute Myeloid Leukemia

Mir-106a-5p and Mir-146a-5p Delivered By Tumor-Derived Exosomes Promote the Induction of Myeloid-Derived Suppressor Cells from Normal Peripheral Blood Mononuclear Cells in Multiple Myeloma

Aberrant EVI1 splicing contributes to EVI1 -rearranged leukemia

UTX maintains the functional integrity of the murine hematopoietic system by globally regulating aging-associated genes

Association of aberrant ASNS imprinting with asparaginase sensitivity and chromosomal abnormality in childhood BCP-ALL

HHEX promotes myeloid transformation in cooperation with mutant ASXL1

Homeobox Transcription Factor Hhex Promotes Myeloid Leukemia in Cooperation with Mutant ASXL1

Genome-Wide Analysis of BRD4-Targets Reveals the Therapeutic Relevance of Simultaneous Targeting of BCR Pathway and IKZF-MYC Axis in Mantle Cell Lymphoma

The enigma of monosomy 7

Aberrant Repression of GFI1 Super-Enhancer By LSD1 Plays an Important Role in Leukemia Programs in Acute Myeloid Leukemia

Acquired expression of Cbl Q367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia

JMJD3 Plays Essential Roles in the Maintenance of Hematopoietic Stem Cells and Leukemic Stem Cells through the Regulation of p16 INK4a

Low Miki Expression in Myelodysplastic Syndromes Results in Polynuclear Cell Formation through Decondensation of Chromosomes in Prolonged Prometaphase

Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2

Generation and Analysis of a Novel Mouse Model for Chronic Myelomonocytic Leukemia (CMML) with Acquired Expression of c-CBL Q367P

Haploinsufficiency Of SAMD9L , An Endosome Fusion Facilitator, In Mice Induces The Development Of Myeloid Malignancies Mimicking Human Diseases With Monosomy 7

Identification of Integrin β3 L718P Mutation in a Pedigree with Autosomal Dominant Macrothrombocytopenia

SLIT1 Mutation in Patients with Acquired Aplastic Anemia: Its Relevance in Immune Pathophysiology

Abnormal Mitosis Due to Impairment of Centrosome Maturation by the Deletion of Candidate 7q- Responsible Genes

Samd9L-Deficient Mice Develop Myeloid Malignancies Mimicking Human Diseases with Monosomy 7

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American Society of Hematology

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ASH Publications

American Society of Hematology

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