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Journal Articles

Pathogenic Significance of the DDX41 p.R525H Variant Revealed By Single-Cell RNA-Seq Analysis

Hirotaka Matsui, Minori Koizumi, Rei Kudo, Akiko Nagamachi, Masahiko Ajiro, Hironori Harada, Yuka Harada, Shigeyuki Shichino, Akihide Yoshimi

Blood (2024) 144 (Supplement 1): 5719.

https://doi.org/10.1182/blood-2024-200394

Published: 2024

Journal Articles

AML-Mrg Mutation Spectrum and Its Prognosis: A Japanese Multicenter Study HM01-02 Analysis with Full Analysis Sets

Blood (2024) 144 (Supplement 1): 6123.

https://doi.org/10.1182/blood-2024-202327

Published: 2024

Journal Articles

Comprehensive Genetic Analysis Revealed Myeloid/Natural Killer (NK) Cell Precursor Acute Leukemia As a Novel Distinctive Leukemia Entity

Akira Nishimura, MD, Kazuaki Yokoyama, MD PhD, Chika Yamagishi, MD, Toshihiko Imamura, MD PhD, Takuya Naruto, MD PhD, Tomohiro Morio, MD PhD, Yukie Tanaka, PhD, Akinori Kanai, PhD, Hirotaka Matsui, MD PhD, Naoko Higuchi, MD, Akiko Takada, MD, Haruna Okuno, MD, Shoji Saito, MD PhD, Shuhei Karakawa, MD PhD, Shogo Kobayashi, MD, Daisuke Hasegawa, MD PhD, Hiroyuki Fujisaki, MD PhD, Daiichiro Hasegawa, MD PhD, Kazutoshi Koike, MD PhD, Takashi Koike, MD, Shinya Rai, MD PhD, Katsutsugu Umeda, MD PhD, Hideki Sano, MD, Yujin Sekinaka, MD PhD, Atsushi Ogawa, MD PhD, Akitoshi Kinoshita, MD PhD, Norio Shiba, MD PhD, Mizuka Miki, MD, Fumihiko Kimura, MD PhD, Hideki Nakayama, MD, Yozo Nakazawa, MD PhD, Takashi Taga, MD PhD, Tomohiko Taki, MD PhD, Souichi Adachi, MD PhD, Atsushi Manabe, MD PhD, Katsuyoshi Koh, MD, Yasushi Ishida, MD PhD, Arinobu Tojo, MD PhD, Masatoshi Takagi, MD PhD

Blood (2020) 136 (Supplement 1): 14–15.

https://doi.org/10.1182/blood-2020-139312

Published: 2020

Journal Articles

Bcor insufficiency promotes initiation and progression of myelodysplastic syndrome

Shiro Tara, Yusuke Isshiki, Yaeko Nakajima-Takagi, Motohiko Oshima, Kazumasa Aoyama, Tomoyuki Tanaka, Daisuke Shinoda, Shuhei Koide, Atsunori Saraya, Satoru Miyagi, Ichiro Manabe, Hirotaka Matsui, Haruhiko Koseki, Vivian J. Bardwell, Atsushi Iwama

Blood (2018) 132 (23): 2470–2483.

https://doi.org/10.1182/blood-2018-01-827964

Published: 2018

Includes: Supplemental data

Journal Articles

Clinical Feature and Genetic Alterations in Myeloid/Natural Killer (NK) Cell Precursor Acute Leukemia and Myeloid/NK Cell Acute Leukemia

Blood (2018) 132 (Supplement 1): 2824.

https://doi.org/10.1182/blood-2018-99-118627

Published: 2018

Journal Articles

Residual Wild-Type Tet2/Tet3 Allele Is the Savior Preventing Mouse Hematopoietic Progenitor Cells from Leukemia Development

Raksha Shrestha, MD, DiMM, Maie Koichiro, MD PhD, Mamiko Sakata-Yanagimoto, MD PhD, Olivier Bernard, Hirotaka Matsui, MD PhD, Yaeko Nakajima-Takagi, PhD, Takayasu Kato, MD PhD, Haruhiko Koseki, PhD, Atsushi Iwama, MD PhD, Shigeru Chiba, MD PhD

Blood (2018) 132 (Supplement 1): 1330.

https://doi.org/10.1182/blood-2018-99-112352

Published: 2018

Journal Articles

The enigma of monosomy 7

Toshiya Inaba, Hiroaki Honda, Hirotaka Matsui

Blood (2018) 131 (26): 2891–2898.

https://doi.org/10.1182/blood-2017-12-822262

Published: 2018

Journal Articles

Aberrant Repression of GFI1 Super-Enhancer By LSD1 Plays an Important Role in Leukemia Programs in Acute Myeloid Leukemia

Goichi Tatsumi, MD, Masahiro Kawahara, MD PhD, Akinori Kanai, PhD, Hirotaka Matsui, MD PhD, Ryusuke Yamamoto, MD, Masakatsu Hishizawa, MD PhD, Toshiya Inaba, MD PhD, Takayoshi Suzuki, PhD, Akira Andoh, MD PhD, Akifumi Kondo Takaori, MD PhD

Blood (2017) 130 (Supplement 1): 3797.

https://doi.org/10.1182/blood.V130.Suppl_1.3797.3797

Published: 2017

Journal Articles

Setdb1 maintains hematopoietic stem and progenitor cells by restricting the ectopic activation of nonhematopoietic genes

Shuhei Koide, Motohiko Oshima, Keiyo Takubo, Satoshi Yamazaki, Eriko Nitta, Atsunori Saraya, Kazumasa Aoyama, Yuko Kato, Satoru Miyagi, Yaeko Nakajima-Takagi, Tetsuhiro Chiba, Hirotaka Matsui, Fumio Arai, Yutaka Suzuki, Hiroshi Kimura, Hiromitsu Nakauchi, Toshio Suda, Yoichi Shinkai, Atsushi Iwama

Blood (2016) 128 (5): 638–649.

https://doi.org/10.1182/blood-2016-01-694810

Published: 2016

Includes: Supplemental data

Journal Articles

Dysregulation of RUNX1 Plays a Critical Role in the Progression of Myelodysplastic Syndromes

Hiroko Sakurai, MD, Yuka Harada, MD PhD, Hirotaka Matsui, MD PhD, Hideaki Nakajima, MD PhD, Toshio Kitamura, MD PhD, Norio Komatsu, MD PhD, Hironori Harada, MD PhD

Blood (2015) 126 (23): 4108.

https://doi.org/10.1182/blood.V126.23.4108.4108

Published: 2015

Journal Articles

Combinatorial Epigenetic Aberration Propagates in Myelodysplastic Syndrome in the Setting of Concurrent Loss of Tet2 and Ezh2

Nagisa Hasegawa, MD, Goro Sashida, MD PhD, Motohiko Oshima, PhD, Hirotaka Matsui, MD PhD, Atsunori Saraya, Changshan Wang, PhD, Tomoya Muto, MD PhD, Chiaki Nakaseko, MD PhD, Koutaro Yokote, MD PhD, Atsushi Iwama, MD PhD

Blood (2015) 126 (23): 712.

https://doi.org/10.1182/blood.V126.23.712.712

Published: 2015

Journal Articles

Low Miki Expression in Myelodysplastic Syndromes Results in Polynuclear Cell Formation through Decondensation of Chromosomes in Prolonged Prometaphase

Akiko Nagamachi, PhD, Yuko Ozaki, PhD, Hirotaka Matsui, MD PhD, Akinori Kanai, PhD, Toshiya Inaba, MD

Blood (2015) 126 (23): 2845.

https://doi.org/10.1182/blood.V126.23.2845.2845

Published: 2015

Journal Articles

Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2

Takeshi Ueda, Akiko Nagamachi, Keiyo Takubo, Norimasa Yamasaki, Hirotaka Matsui, Akinori Kanai, Yuichiro Nakata, Kenichiro Ikeda, Takaaki Konuma, Hideaki Oda, Linda Wolff, Zen-ichiro Honda, Xudong Wu, Kristian Helin, Atsushi Iwama, Toshio Suda, Toshiya Inaba, Hiroaki Honda

Blood (2015) 125 (22): 3437–3446.

https://doi.org/10.1182/blood-2014-03-562694

Published: 2015

Includes: Supplemental data

Journal Articles

The Biological Function of DNA Hypermethylation in Murine MDS Model Lacking Tet2 and Ezh2

Nagisa Hasegawa, MD, Goro Sashida, MD PhD, Motohiko Oshima, PhD, Hirotaka Matsui, MD PhD, Changshan Wang, PhD, Tomoya Muto, MD PhD, Chiaki Nakaseko, MD PhD, Kotaro Yokote, MD PhD, Atsushi Iwama, MD PhD

Blood (2014) 124 (21): 4596.

https://doi.org/10.1182/blood.V124.21.4596.4596

Published: 2014

Journal Articles

SETBP1 Mutations Drive Leukemic Transformation in ASXL1 -Mutated MDS

Daichi Inoue, MD PhD, Hirotaka Matsui, MD PhD, Hsin-An Hou, MD PhD, Wen-Chien Chou, MD PhD, Akiko Nagamachi, PhD, Jiro Kitaura, MD PhD, Kimihito Cojin Kawabata, MD PhD, Katsuhiro Togami, MD PhD, Reina Nagase, Sayuri Horikawa, Makoto Saika, MD, Jean-Baptiste Micol, MD, Yasutaka Hayashi, MD, Yuka Harada, MD PhD, Hironori Harada, MD PhD, Hwei-Fang Tien, MD PhD, Omar Abdel-Wahab, MD, Toshio Kitamura, MD PhD

Blood (2014) 124 (21): 525.

https://doi.org/10.1182/blood.V124.21.525.525

Published: 2014

Journal Articles

Epigenetic Regulation of Hematopoietic Stem and Progenitor Cells By the Eset Histone Methyltranferas

Shuhei Koide, Keiyo Takubo, MD PhD, Motohiko Oshima, PhD, Satoru Miyagi, PhD, Hirotaka Matsui, MD PhD, Hiroshi Kimura, PhD, Changshan Wang, PhD, George R Wendt, Shogo Yabata, Yoichi Shinkai, MD PhD, Toshio Suda, MD PhD, Atsushi Iwama, MD PhD

Blood (2014) 124 (21): 765.

https://doi.org/10.1182/blood.V124.21.765.765

Published: 2014

Journal Articles

Haploinsufficiency Of SAMD9L , An Endosome Fusion Facilitator, In Mice Induces The Development Of Myeloid Malignancies Mimicking Human Diseases With Monosomy 7

Hirotaka Matsui, MD, PhD, Akiko Nagamachi, Akinori Kanai, PhD, Yuko Ozaki, Hiroaki Honda, MD, PhD, Toshiya Inaba, MD, PhD

Blood (2013) 122 (21): 227.

https://doi.org/10.1182/blood.V122.21.227.227

Published: 2013

Journal Articles

RUNX1/AML1 mutant collaborates with BMI1 overexpression in the development of human and murine myelodysplastic syndromes

Yuka Harada, Daichi Inoue, Ye Ding, Jun Imagawa, Noriko Doki, Hirotaka Matsui, Takashi Yahata, Hiromichi Matsushita, Kiyoshi Ando, Goro Sashida, Atsushi Iwama, Toshio Kitamura, Hironori Harada

Blood (2013) 121 (17): 3434–3446.

https://doi.org/10.1182/blood-2012-06-434423

Published: 2013

Includes: Supplemental data

Journal Articles

Identification of Integrin β3 L718P Mutation in a Pedigree with Autosomal Dominant Macrothrombocytopenia

Yoshiyuki Kobayashi, MD, Hirotaka Matsui, MD, Akinori Kanai, PhD, Miyuki Tsumura, MSc, Satoshi Okada, MD, PhD, Mizuka Miki, MD, Kazuhiro Nakamura, MD, PhD, Shinji Kunishima, PhD, Toshiya Inaba, MD, PhD, Masao Kobayashi, MD, PhD

Blood (2012) 120 (21): 1081.

https://doi.org/10.1182/blood.V120.21.1081.1081

Published: 2012

Journal Articles

SLIT1 Mutation in Patients with Acquired Aplastic Anemia: Its Relevance in Immune Pathophysiology

Chizuru Saito, MD, Kohei Hosokawa, MD, Takamasa Katagiri, PhD, Akinori Kanai, PhD, Hirotaka Matsui, MD, Toshiya Inaba, MD, PhD, Masafumi Taniwaki, MD, PhD, Hirohito Yamazaki, MD, PhD, Shinji Nakao, MD, PhD

Blood (2012) 120 (21): 645.

https://doi.org/10.1182/blood.V120.21.645.645

Published: 2012

NARROW

Pathogenic Significance of the DDX41 p.R525H Variant Revealed By Single-Cell RNA-Seq Analysis

AML-Mrg Mutation Spectrum and Its Prognosis: A Japanese Multicenter Study HM01-02 Analysis with Full Analysis Sets

Comprehensive Genetic Analysis Revealed Myeloid/Natural Killer (NK) Cell Precursor Acute Leukemia As a Novel Distinctive Leukemia Entity

Bcor insufficiency promotes initiation and progression of myelodysplastic syndrome

Clinical Feature and Genetic Alterations in Myeloid/Natural Killer (NK) Cell Precursor Acute Leukemia and Myeloid/NK Cell Acute Leukemia

Residual Wild-Type Tet2/Tet3 Allele Is the Savior Preventing Mouse Hematopoietic Progenitor Cells from Leukemia Development

The enigma of monosomy 7

Aberrant Repression of GFI1 Super-Enhancer By LSD1 Plays an Important Role in Leukemia Programs in Acute Myeloid Leukemia

Setdb1 maintains hematopoietic stem and progenitor cells by restricting the ectopic activation of nonhematopoietic genes

Dysregulation of RUNX1 Plays a Critical Role in the Progression of Myelodysplastic Syndromes

Combinatorial Epigenetic Aberration Propagates in Myelodysplastic Syndrome in the Setting of Concurrent Loss of Tet2 and Ezh2

Low Miki Expression in Myelodysplastic Syndromes Results in Polynuclear Cell Formation through Decondensation of Chromosomes in Prolonged Prometaphase

Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2

The Biological Function of DNA Hypermethylation in Murine MDS Model Lacking Tet2 and Ezh2

SETBP1 Mutations Drive Leukemic Transformation in ASXL1 -Mutated MDS

Epigenetic Regulation of Hematopoietic Stem and Progenitor Cells By the Eset Histone Methyltranferas

Haploinsufficiency Of SAMD9L , An Endosome Fusion Facilitator, In Mice Induces The Development Of Myeloid Malignancies Mimicking Human Diseases With Monosomy 7

RUNX1/AML1 mutant collaborates with BMI1 overexpression in the development of human and murine myelodysplastic syndromes

Identification of Integrin β3 L718P Mutation in a Pedigree with Autosomal Dominant Macrothrombocytopenia

SLIT1 Mutation in Patients with Acquired Aplastic Anemia: Its Relevance in Immune Pathophysiology

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American Society of Hematology

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American Society of Hematology

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