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Olivier Bernard
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Journal Articles

Post-Therapeutic Tumor Losses of B-Cell Receptor Components CD20/CD19, a New Challenge in the Management of Patients with Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Thomas Hueso, Jessy Alchidiac, Maria-Rosa Ghigna, Arnaud Pages, Cyril Quivoron, Camille Bigenwald, Loic Renaud, Cristina Castilla-Llorente, Alexandre Eeckhoutte, Serge Bologna, Veronique Morel, Vincent Delwail, Pierre Feugier, Catherine Thieblemont, Olivier Bernard, Peggy Dartigues, Christophe Massard, Vincent Ribrag, Jean-Marie Michot
Journal: Blood
Blood (2024) 144 (Supplement 1): 474.
https://doi.org/10.1182/blood-2024-203664
Published: 2024
Journal Articles

A Multiomic Analysis of Waldenstrom's Macroglobulinemia Identifies Three Subtypes of Disease Based on Impaired Plasma Cell Differentiation

Dylan C Gagler, Hussein Ghamlouch, Di Zhang, Patrick Blaney, Marine Armand, Alexandre Eeckhoutte, Amina Joudat, Michael Degaud, Michela Esposito, Gaurav Varma, Yubao Wang, Sanxiong Liu, Oscar B Lahoud, David Kaminetzsky, Marc J Braunstein, Florence Nguyen-Khac, Brian A. Walker, Damien Roos-Weil, Faith E Davies, Olivier Bernard, Gareth Morgan
Journal: Blood
Blood (2024) 144 (Supplement 1): 857.
https://doi.org/10.1182/blood-2024-210654
Published: 2024
Journal Articles

High frequency of clonal hematopoiesis in Erdheim-Chester disease

Fleur Cohen Aubart, Damien Roos-Weil, Marine Armand, Alice Marceau-Renaut, Jean-François Emile, Nicolas Duployez, Frédéric Charlotte, Stéphanie Poulain, Raphael Lhote, Zofia Hélias-Rodzewicz, Véronique Della-Valle, Olivier Bernard, Karim Maloum, Florence Nguyen-Khac, Jean Donadieu, Zahir Amoura, Omar Abdel-Wahab, Julien Haroche
Journal: Blood
Blood (2021) 137 (4): 485–492.
https://doi.org/10.1182/blood.2020005101
Published: 2021
Includes: Supplemental data
Journal Articles

Residual Wild-Type Tet2/Tet3 Allele Is the Savior Preventing Mouse Hematopoietic Progenitor Cells from Leukemia Development

Raksha Shrestha, MD, DiMM, Maie Koichiro, MD PhD, Mamiko Sakata-Yanagimoto, MD PhD, Olivier Bernard, Hirotaka Matsui, MD PhD, Yaeko Nakajima-Takagi, PhD, Takayasu Kato, MD PhD, Haruhiko Koseki, PhD, Atsushi Iwama, MD PhD, Shigeru Chiba, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1330.
https://doi.org/10.1182/blood-2018-99-112352
Published: 2018
Journal Articles

Genetic Characterization of B-Cell Prolymphocytic Leukemia (B-PLL): A Hierarchical Prognostic Model Involving MYC and TP53 Abnormalities. on Behalf of the Groupe Francophone De Cytogenetique Hematologique (GFCH) and the French Innovative Leukemia Organization (FILO) Group

Elise Chapiro, MD PhD, Damien Roos-Weil, MD, Nadia Bougacha, Clementine Gabillaud, Clémentine Dillard, Elodie Pramil, Melanie Yon, Karim Maloum, MD PhD, Catherine Settegrana, Lucile Baseggio, MD, Claude Lesty, Frederic Davi, MD PhD, Magali Le Garff-Tavernier, M'boyba Khadija Diop, Nathalie M Droin, PhD, Philippe Dessen, Veronique Leblond, Caroline Algrin, Simon Bouzy, Virginie Eclache, Baptiste Gaillard, Evelyne Callet-Bauchu, Marc Muller, MD, Christine Lefebvre, MD PhD, Nathalie Nadal, Antoine Ittel, PharmD, Stéphanie Struski, Marie-Agnes Collonge-Rame, Benoit Quilichini, Sandra Fert-Ferrer, Nathalie Auger, Isabelle Radford-Weiss, Lena Wagner, Sebastian Scheinost, Thorsten Zenz, MD, Santos Susin, Olivier Bernard, Florence Nguyen-Khac, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 943.
https://doi.org/10.1182/blood-2018-99-115085
Published: 2018
Journal Articles

Clonal Heterogeneity in Differentiation Response and Resistance to the IDH2 Inhibitor Enasidenib in Acute Myeloid Leukemia

Lynn Quek, FRCPath, DPhil, MBBS, Muriel David, Alison Kennedy, MSc, Marlen Metzner, MSc, Michael Amatangelo, PhD, Alan H. Shih, MD PhD, Bilyana Stoilova, PhD, Dimitris Karamitros, PhD, Cyril Quivoron, Mael Heiblig, MD, Christophe Willekens, MD, Veronique Saada, Andrew Peniket, Olivier Bernard, Sam Agresta, MD, Katharine Yen, Eytan M. Stein, MD, Stephane De Botton, Anjan Thakurta, PhD, Ross L. Levine, MD, Virginie Penard-Lacronique, PhD, Paresh Vyas, DPhil, FRCP, FRCPath, MRCP, MRCPath
Journal: Blood
Blood (2017) 130 (Supplement 1): 724.
https://doi.org/10.1182/blood.V130.Suppl_1.724.724
Published: 2017
Journal Articles

Clonal Evolution in CLL

Simon Bouzy, Marine Armand, Clementine Gabillaud, Elise Chapiro, Nadia Bougacha, Fotini Kostopoulou, PhD, Frederic Davi, MD PhD, Magali Le Garff-Tavernier, Karim Maloum, Veronique Leblond, Veronique Morel, Damien Roos-Weil, Anne Lavaud, Jean Gabarre, Choquet Sylvain, Santos Susin, Olivier Bernard, Florence Nguyen-Khac, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3008.
https://doi.org/10.1182/blood.V130.Suppl_1.3008.3008
Published: 2017
Journal Articles

The Gain of the Short Arm of Chromosome 2 (2pgain) Plays an Important Role in CLL Drug Resistance, and Has to be Systematically Considered before Deciding an Adapted Therapy

Fotini Kostopoulou, PhD, Nadia Bougacha, Clementine Gabillaud, Elise Chapiro, Simon Bouzy, Magali Le Garff-Tavernier, Pharm, PhD, Karim Maloum, Choquet Sylvain, Veronique Leblond, Jean Gabarre, Anne Lavaud, Veronique Morel, Damien Roos-Weil, Madalina Uzunov, Romain Guieze, MD PhD, Olivier Tournilhac, MD PhD, Santos Susin, Olivier Bernard, Florence Nguyen-Khac, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1729.
https://doi.org/10.1182/blood.V130.Suppl_1.1729.1729
Published: 2017
Journal Articles

AG-120, an Oral, Selective, First-in-Class, Potent Inhibitor of Mutant IDH1, Reduces Intracellular 2HG and Induces Cellular Differentiation in TF-1 R132H Cells and Primary Human IDH1 Mutant AML Patient Samples Treated Ex Vivo

Erica Hansen, Cyril Quivoron, Kim Straley, René M Lemieux, Janeta Popovici-Muller, Hossein Sadrzadeh, Amir T Fathi, Camelia Gliser, Muriel David, Véronique Saada, Jean-Baptiste Micol, Olivier Bernard, Marion Dorsch, Hua Yang, Michael Su, Sam Agresta, Stéphane de Botton, Virginie Penard-Lacronique, Katharine Yen
Journal: Blood
Blood (2014) 124 (21): 3734.
https://doi.org/10.1182/blood.V124.21.3734.3734
Published: 2014
Journal Articles

AG-221, an Oral, Selective, First-in-Class, Potent IDH2-R140Q Mutant Inhibitor, Induces Differentiation in a Xenotransplant Model

Cyril Quivoron, Muriel David, Kim Straley, Jeremy Travins, Hyeryun Kim, Yue Chen, Dongwei Zhu, Véronique Saada, Olivia Bawa, Paule Opolon, Mélanie Polrot, Jean-Baptiste Micol, Christophe Willekens, Olivier Bernard, Hua Yang, Sam Agresta, Stéphane de Botton, Katharine Yen, Virginie Penard-Lacronique
Journal: Blood
Blood (2014) 124 (21): 3735.
https://doi.org/10.1182/blood.V124.21.3735.3735
Published: 2014
Journal Articles

TET2 Favors Mesoderm and Hematopoietic Differentiation in Human Embryonic Stem Cells

Barbara da Costa Reis Monte Mor, Ph.D, Thierry Langlois, Nathalie Droin, Ph.D, Elodie Pronier, Jean-Pierre Le Couédic, Nathalie Auger, M.D., Carole Almire, M.D., Thomas Mercher, PhD, Francois Delhommeau, PharmD, PhD, Debili Najet, Ph.D, Olivier Bernard, Eric Solary, Isabelle Plo, Ph.D, William Vainchenker, MD., Ph.D
Journal: Blood
Blood (2011) 118 (21): 2418.
https://doi.org/10.1182/blood.V118.21.2418.2418
Published: 2011
Journal Articles

IDH1/2, TET2 and DNMT3A Mutations Are Not Mutually Exclusive in Secondary Acute Myeloid Leukemias,

Olivier Kosmider, Olivier LaRochelle, Marie-Magdelaine Coude, Veronique Mansat-De Mas, Eric Delabesse, Pascale Cornillet-Lefebvre, Odile Blanchet, Christian Recher, Alain Delmer, MD, Sophie Raynaud, Catherine Lacombe, Olivier Bernard, Norbert Ifrah, Francois Dreyfus, Michaela Fontenay
Journal: Blood
Blood (2011) 118 (21): 3556.
https://doi.org/10.1182/blood.V118.21.3556.3556
Published: 2011
Journal Articles

Novel Mutations: Dissecting Pathogenetic Contribution

William Vainchenker, MD, PhD, Francois Delhommeau, PharmD, PhD, Isabelle Plo, Jean-Luc Villeval, Olivier Bernard
Journal: Blood
Blood (2010) 116 (21): SCI-34.
https://doi.org/10.1182/blood.V116.21.SCI-34.SCI-34
Published: 2010
Journal Articles

TET2 Mutations in Secondary Acute Myeloid Leukemias: A French Retrospective Study

Olivier Kosmider, Véronique De Mas, Eric Delabesse, Pascale Cornillet-lefevre, Odile Blanchet, Christian Récher, Sophie Raynaud, Catherine Lacombe, Olivier Bernard, Norbert Ifrah, Francois Dreyfus, Michaëla Fontenay on behalf of the GOELAMS
Journal: Blood
Blood (2010) 116 (21): 176.
https://doi.org/10.1182/blood.V116.21.176.176
Published: 2010
Journal Articles

Analysis of the Ten-Eleven Translocation 2 ( TET2 ) gene in familial myeloproliferative neoplasms

Brief Report
Cécile Saint-Martin, Gwendoline Leroy, François Delhommeau, Gérard Panelatti, Sabrina Dupont, Chloé James, Isabelle Plo, Dominique Bordessoule, Christine Chomienne, André Delannoy, Alain Devidas, Martine Gardembas-Pain, Françoise Isnard, Yves Plumelle, Olivier Bernard, William Vainchenker, Albert Najman, Christine Bellanné-Chantelot, the French Group of Familial Myeloproliferative Disorders
Journal: Blood
Blood (2009) 114 (8): 1628–1632.
https://doi.org/10.1182/blood-2009-01-197525
Published: 2009
Includes: Supplemental data
Journal Articles

IGH@ Translocations Involving the Pseudoautosomal Region 1 (PAR1) of Both Sex Chromosomes Deregulate the Cytokine Receptor-Like Factor 2 (CRLF2) Gene in B Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL)

Lisa J Russell, Melania Capasso, Inga Vater, Anthony V Moorman, Takashi Akasaka, Lana Harder, Olaf Heidenreich, Lee Machado, Stephan Gest, Jonathan C Strefford, Thiruppavai Chandrasekaran, Holger Tönnies, Aneela Majid, Olivier Bernard, Martin JS Dyer, Reiner Siebert, Christine J Harrison
Journal: Blood
Blood (2008) 112 (11): 787.
https://doi.org/10.1182/blood.V112.11.787.787
Published: 2008
Journal Articles

TET2 Is a Novel Tumor Suppressor Gene Inactivated in Myeloproliferative Neoplasms: Identification of a Pre-JAK2 V617F Event

Francois Delhommeau, Sabrina Dupont, Chloe James, MD, PhD, Aline Masse, Jean Pierre le Couedic, Veronique Della Valle, Antonio Alberdi, Philippe Dessen, Michaela Fontenay, Nicole Casadevall, MD, Jean Soulier, MD, PhD, Olivier Bernard, William Vainchenker
Journal: Blood
Blood (2008) 112 (11): lba-3.
https://doi.org/10.1182/blood.V112.11.lba-3.lba-3
Published: 2008
Journal Articles

OTT-MAL Activates the Notch Signaling Transcription Factor RBPJ and Cooperates with Mutant MPL to Induce Acute Megakaryoblastic Leukemia

Thomas Mercher, Ph.D, Glen D. Raffel, MD, PhD, Sandra A Moore, Melanie G Cornejo, Dominique Baudry-Bluteau, Ph.D, Nicolas Cagnard, Jonathan Jesneck, Yana Pikman, Dana E. Cullen, Ifor Williams, Koichi Akashi, MD, PhD, Hirokazu Shigematsu, Jean-Pierre Bourquin, MD, PhD, Marco Giovannini, MD, PhD, William Vainchenker, Ross L Levine, MD, Benjamin H. Lee, MD, PhD, Olivier Bernard, D. Gary Gilliland
Journal: Blood
Blood (2008) 112 (11): 508.
https://doi.org/10.1182/blood.V112.11.508.508
Published: 2008
Journal Articles

High-Throughput Sequence Analysis of the Tyrosine Kinome in Acute Myeloid Leukemia.

Marc Loriaux, Ross Levine, Jeffrey Tyner, Stephan Frohling, Claudia Scholl, Eric Stoffregen, Gerlinde Wernig, Heidi Erickson, Chris Eide, Roland Berger, Olivier Bernard, James Griffin, Richard Stone, Matthew Meyerson, Michael Heinrich, Michael Deininger, Gary Gilliland, Brian Druker
Journal: Blood
Blood (2007) 110 (11): 886.
https://doi.org/10.1182/blood.V110.11.886.886
Published: 2007
Journal Articles

Age-related phenotypic and oncogenic differences in T-cell acute lymphoblastic leukemias may reflect thymic atrophy

Vahid Asnafi, Kheira Beldjord, Marta Libura, Patrick Villarese, Corrine Millien, Paola Ballerini, Emilienne Kuhlein, Marina Lafage-Pochitaloff, Eric Delabesse, Olivier Bernard, Elizabeth Macintyre
Journal: Blood
Blood (2004) 104 (13): 4173–4180.
https://doi.org/10.1182/blood-2003-11-3944
Published: 2004