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Journal Articles

Presence of atypical thrombopoietin receptor (MPL) mutations in triple-negative essential thrombocythemia patients

Blood (2016) 127 (3): 333–342.

https://doi.org/10.1182/blood-2015-07-661983

Published: 2016

Includes: Supplemental data

Journal Articles

Use Of 46/1 Haplotype Permits To Follow JAK2 V617F Clonal Architecture In PV Patients: Clonal Evolution and Impact Of IFNα Treatment

Salma Hasan, PhD student, Bruno Cassinat, PharmD, PhD, Jean-Pierre Le Couédic, Fabrizia Favale, Barbara Monte-Mor, Catherine Lacout, Eric Solary, MD, PhD, Jean-Luc Villeval, PhD, Nicole Casadevall, MD, Jean-Jacques Kiladjian, MD, PhD, William Vainchenker, MD, PhD, Isabelle Plo, Ph.D

Blood (2013) 122 (21): 4109.

https://doi.org/10.1182/blood.V122.21.4109.4109

Published: 2013

Journal Articles

46/1 Haplotype Permits to Follow JAK2 Homologous Recombination: Modeling JAK2 V617F clonal Architecture in PV Patients

Salma Hasan, PhD Student, Jean Pierre Le Couedic, Fabrizia Favale, Barbara Monte-Mor, Catherine Lacout, Nicole Casadevall, MD, Eric Solary, Jean-Luc Villeval, PhD, Isabelle Plo, Ph.D, William Vainchenker, MD, PhD

Blood (2012) 120 (21): 1757.

https://doi.org/10.1182/blood.V120.21.1757.1757

Published: 2012

Journal Articles

Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors

Blood (2011) 118 (9): 2551–2555.

https://doi.org/10.1182/blood-2010-12-324707

Published: 2011

Includes: Supplemental data

Journal Articles

TET2 Is a Novel Tumor Suppressor Gene Inactivated in Myeloproliferative Neoplasms: Identification of a Pre-JAK2 V617F Event

Francois Delhommeau, Sabrina Dupont, Chloe James, MD, PhD, Aline Masse, Jean Pierre le Couedic, Veronique Della Valle, Antonio Alberdi, Philippe Dessen, Michaela Fontenay, Nicole Casadevall, MD, Jean Soulier, MD, PhD, Olivier Bernard, William Vainchenker

Blood (2008) 112 (11): lba-3.

https://doi.org/10.1182/blood.V112.11.lba-3.lba-3

Published: 2008

Journal Articles

Evidence for MPL W515L/K mutations in hematopoietic stem cells in primitive myelofibrosis

Ronan Chaligné, Chloé James, Carole Tonetti, Rodolphe Besancenot, Jean Pierre Le Couédic, Fanny Fava, Fréderic Mazurier, Isabelle Godin, Karim Maloum, Frédéric Larbret, Yann Lécluse, William Vainchenker, Stéphane Giraudier

Blood (2007) 110 (10): 3735–3743.

https://doi.org/10.1182/blood-2007-05-089003

Published: 2007

Journal Articles

The JAK2 617V > F mutation triggers erythropoietin hypersensitivity and terminal erythroid amplification in primary cells from patients with polycythemia vera

Sabrina Dupont, Aline Massé, Chloé James, Irène Teyssandier, Yann Lécluse, Frédéric Larbret, Valérie Ugo, Patrick Saulnier, Serge Koscielny, Jean Pierre Le Couédic, Nicole Casadevall, William Vainchenker, François Delhommeau

Blood (2007) 110 (3): 1013–1021.

https://doi.org/10.1182/blood-2006-10-054940

Published: 2007

Includes: Supplemental data

Journal Articles

Proplatelet formation is regulated by the Rho/ROCK pathway

Yunhua Chang, Frédéric Auradé, Frédéric Larbret, Yanyan Zhang, Jean-Pierre Le Couedic, Laurence Momeux, Jerôme Larghero, Jacques Bertoglio, Fawzia Louache, Elisabeth Cramer, William Vainchenker, Najet Debili

Blood (2007) 109 (10): 4229–4236.

https://doi.org/10.1182/blood-2006-04-020024

Published: 2007

Journal Articles

Evidence That the MPL 515L and 515K Mutations Occur in a Lympho-Myeloid Progenitor in Idiopathic Myelofibrosis and Are Associated with TPO Hypersensitivity.

Ronan Chaligne, Jean-Pierre Le Couedic, sRA, Carole Tonetti, sRA, Rodolphe Besancenot, MD, Orianne Wagner-Ballon, MD, PhD, Najet Debili, PhD, William Vainchenker, MD, PhD, Stephane Giraudier, MD, PhD

Blood (2006) 108 (11): 117.

https://doi.org/10.1182/blood.V108.11.117.117

Published: 2006

Journal Articles

Evidence that the JAK2 G1849T (V617F) mutation occurs in a lymphomyeloid progenitor in polycythemia vera and idiopathic myelofibrosis

François Delhommeau, Sabrina Dupont, Carole Tonetti, Aline Massé, Isabelle Godin, Jean-Pierre Le Couedic, Najet Debili, Patrick Saulnier, Nicole Casadevall, William Vainchenker, Stéphane Giraudier

Blood (2006) 109 (1): 71–77.

https://doi.org/10.1182/blood-2006-03-007146

Published: 2006

Includes: Supplemental data

Journal Articles

Proplatelet Formation Is Regulated by the Rho/Rock Pathway.

Yunhua Chang, PhD, Frederic Aurade, PhD, Frederic Larbret, Jean Pierre Le Couedic, Laurence Momeux, Yan Yan Zhang, PhD, Jerome Larghero, MD, Fawzia Louache, PhD, Jacques Bertoglio, MD, Elisabeth Cramer, PhD, William Vainchenker, MD, PhD, Najet Debili, PhD

Blood (2005) 106 (11): 3147.

https://doi.org/10.1182/blood.V106.11.3147.3147

Published: 2005

Journal Articles

Megakaryocyte polyploidization is associated with a functional gene amplification

Hana Raslova, Lydia Roy, Claire Vourc'h, Jean Pierre Le Couedic, Olivier Brison, Didier Metivier, Jean Feunteun, Guido Kroemer, Najet Debili, William Vainchenker

Blood (2003) 101 (2): 541–544.

https://doi.org/10.1182/blood-2002-05-1553

Published: 2003

Journal Articles

Role of p21 Cip1/Waf1 in cell-cycle exit of endomitotic megakaryocytes

Véronique Baccini, Lydia Roy, Natacha Vitrat, Hédia Chagraoui, Siham Sabri, Jean-Pierre Le Couedic, Najet Debili, Françoise Wendling, William Vainchenker

Blood (2001) 98 (12): 3274–3282.

https://doi.org/10.1182/blood.V98.12.3274

Published: 2001

Journal Articles

Cloning, characterization, and functional studies of human and mouse glycoprotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamily

Martine Jandrot-Perrus, Samantha Busfield, Anne-Helène Lagrue, Ximing Xiong, Najet Debili, Troy Chickering, Jean-Pierre Le Couedic, Andrew Goodearl, Barry Dussault, Christopher Fraser, William Vainchenker, Jean-Luc Villeval

Blood (2000) 96 (5): 1798–1807.

https://doi.org/10.1182/blood.V96.5.1798

Published: 2000

Journal Articles

Existence of a differentiation blockage at the stage of a megakaryocyte precursor in the thrombocytopenia and absent radii (TAR) syndrome

Rémi Letestu, Natacha Vitrat, Aline Massé, Jean-Pierre Le Couedic, Vladimir Lazar, Philippe Rameau, Françoise Wendling, Jacqueline Vuillier, Patrick Boutard, Emmanuel Plouvier, Mireille Plasse, Rémi Favier, William Vainchenker, Najet Debili

Blood (2000) 95 (5): 1633–1641.

https://doi.org/10.1182/blood.V95.5.1633.005k25_1633_1641

Published: 2000

Journal Articles

Autonomous Megakaryocyte Growth in Essential Thrombocythemia and Idiopathic Myelofibrosis Is Not Related to a c-mpl Mutation or to an Autocrine Stimulation by Mpl-L

Anne Laure Taksin, Jean-Pierre Le Couedic, Isabelle Dusanter-Fourt, Aline Massé, Stéphane Giraudier, André Katz, Françoise Wendling, William Vainchenker, Nicole Casadevall, Najet Debili

Blood (1999) 93 (1): 125–139.

https://doi.org/10.1182/blood.V93.1.125

Published: 1999

NARROW

Presence of atypical thrombopoietin receptor (MPL) mutations in triple-negative essential thrombocythemia patients

Use Of 46/1 Haplotype Permits To Follow JAK2 V617F Clonal Architecture In PV Patients: Clonal Evolution and Impact Of IFNα Treatment

46/1 Haplotype Permits to Follow JAK2 Homologous Recombination: Modeling JAK2 V617F clonal Architecture in PV Patients

Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors

TET2 Is a Novel Tumor Suppressor Gene Inactivated in Myeloproliferative Neoplasms: Identification of a Pre-JAK2 V617F Event

Evidence for MPL W515L/K mutations in hematopoietic stem cells in primitive myelofibrosis

The JAK2 617V > F mutation triggers erythropoietin hypersensitivity and terminal erythroid amplification in primary cells from patients with polycythemia vera

Proplatelet formation is regulated by the Rho/ROCK pathway

Evidence That the MPL 515L and 515K Mutations Occur in a Lympho-Myeloid Progenitor in Idiopathic Myelofibrosis and Are Associated with TPO Hypersensitivity.

Evidence that the JAK2 G1849T (V617F) mutation occurs in a lymphomyeloid progenitor in polycythemia vera and idiopathic myelofibrosis

Proplatelet Formation Is Regulated by the Rho/Rock Pathway.

Megakaryocyte polyploidization is associated with a functional gene amplification

Role of p21 Cip1/Waf1 in cell-cycle exit of endomitotic megakaryocytes

Cloning, characterization, and functional studies of human and mouse glycoprotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamily

Existence of a differentiation blockage at the stage of a megakaryocyte precursor in the thrombocytopenia and absent radii (TAR) syndrome

Autonomous Megakaryocyte Growth in Essential Thrombocythemia and Idiopathic Myelofibrosis Is Not Related to a c-mpl Mutation or to an Autocrine Stimulation by Mpl-L

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American Society of Hematology

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American Society of Hematology

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