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Journal Articles

SRSF2-P95Hdelays Myelofibrosis Development through Altered JAK/STAT Signaling in JAK2-V617F Megakaryocytes

Blood (2021) 138 (Supplement 1): 2544.

https://doi.org/10.1182/blood-2021-149757

Published: 2021

Journal Articles

Modeling the Behavior of Hematopoietic Compartments from Stem to Red Cells in Murine Steady State and Stress Hematopoiesis

Celine Bonnet, BSc, Panhong Gou, BSc, Vincent Bensaye, PhD Associate Professor, Catherine Lacout, Ingeneer, Karine Bailly, Ingeneer, Marie-helene Schlagetter, MD PhD, Evelyne Lauret, PhD, Sylvie Meleard, PhD Professor, Stephane Giraudier, MD PhD

Blood (2019) 134 (Supplement_1): 2224.

https://doi.org/10.1182/blood-2019-123704

Published: 2019

Journal Articles

MIR150 Is Involved in the Monocyte Subset Differentiation and Its Down-Regulation Leads to Classical Monocyte Accumulation in Chronic Myelomonocytic Leukemia

Dorothee Selimoglu-Buet, PhD, Julie Riviere, PhD, Margot Morabito, Catherine Lacout, Aurelie Chauveau, MD, Camille Debord, Raphaël Itzykson, MD PhD, Pierre Fenaux, MD PhD, Nathalie M. Droin, PhD, Éric Solary, MD PhD

Blood (2016) 128 (22): 1133.

https://doi.org/10.1182/blood.V128.22.1133.1133

Published: 2016

Journal Articles

HSP27: A Therapeutic Target in Myelofibrosis

Margaux Sevin, Nicolas Pernet, Franck Vitte, MD, Selim Ramla, Paul Sagot, MD PhD, Laurent Martin, MD PhD, Jean Luc Villeval, PhD, Catherine Lacout, Isabelle Plo, PhD, Carmen Garrido, PhD, Francois Girodon, MD PhD, Aurelie de Thonel, PhD

Blood (2016) 128 (22): 1963.

https://doi.org/10.1182/blood.V128.22.1963.1963

Published: 2016

Journal Articles

JAK2 and MPL protein levels determine TPO-induced megakaryocyte proliferation vs differentiation

Rodolphe Besancenot, Damien Roos-Weil, Carole Tonetti, Hadjer Abdelouahab, Catherine Lacout, Florence Pasquier, Christophe Willekens, Philippe Rameau, Yann Lecluse, Jean-Baptiste Micol, Stefan N. Constantinescu, William Vainchenker, Eric Solary, Stéphane Giraudier

Blood (2014) 124 (13): 2104–2115.

https://doi.org/10.1182/blood-2014-03-559815

Published: 2014

Includes: Supplemental data

Journal Articles

Hemostatic disorders in a JAK2 V617F -driven mouse model of myeloproliferative neoplasm

Lamia Lamrani, Catherine Lacout, Véronique Ollivier, Cécile V. Denis, Elizabeth Gardiner, Benoit Ho Tin Noe, William Vainchenker, Jean-Luc Villeval, Martine Jandrot-Perrus

Blood (2014) 124 (7): 1136–1145.

https://doi.org/10.1182/blood-2013-10-530832

Published: 2014

Includes: Supplemental data

Journal Articles

Effect Of The JAK1/2 Inhibitor GS-0387 (momelotinib) On The Anemia Associated With a Preclinical Murine Model Of Human Primary Myelofibrosis

Jean-Luc Villeval, PhD, Claudine Moratal, M2, Franck Debeurme, Catherine Lacout, Eric Solary, MD, PhD, William Vainchenker, MD, PhD, Christopher J Burns, PhD, Gregg Smith, PhD

Blood (2013) 122 (21): 2851.

https://doi.org/10.1182/blood.V122.21.2851.2851

Published: 2013

Journal Articles

Use Of 46/1 Haplotype Permits To Follow JAK2 V617F Clonal Architecture In PV Patients: Clonal Evolution and Impact Of IFNα Treatment

Salma Hasan, PhD student, Bruno Cassinat, PharmD, PhD, Jean-Pierre Le Couédic, Fabrizia Favale, Barbara Monte-Mor, Catherine Lacout, Eric Solary, MD, PhD, Jean-Luc Villeval, PhD, Nicole Casadevall, MD, Jean-Jacques Kiladjian, MD, PhD, William Vainchenker, MD, PhD, Isabelle Plo, Ph.D

Blood (2013) 122 (21): 4109.

https://doi.org/10.1182/blood.V122.21.4109.4109

Published: 2013

Journal Articles

JAK2 V617F expression in mice amplifies early hematopoietic cells and gives them a competitive advantage that is hampered by IFNα

Salma Hasan, Catherine Lacout, Caroline Marty, Marie Cuingnet, Eric Solary, William Vainchenker, Jean-Luc Villeval

Blood (2013) 122 (8): 1464–1477.

https://doi.org/10.1182/blood-2013-04-498956

Published: 2013

Includes: Supplemental data

Journal Articles

46/1 Haplotype Permits to Follow JAK2 Homologous Recombination: Modeling JAK2 V617F clonal Architecture in PV Patients

Salma Hasan, PhD Student, Jean Pierre Le Couedic, Fabrizia Favale, Barbara Monte-Mor, Catherine Lacout, Nicole Casadevall, MD, Eric Solary, Jean-Luc Villeval, PhD, Isabelle Plo, Ph.D, William Vainchenker, MD, PhD

Blood (2012) 120 (21): 1757.

https://doi.org/10.1182/blood.V120.21.1757.1757

Published: 2012

Journal Articles

JAK2 V617F Promotes Stem Cell Amplification Driving MPN Clonal Dominance in Mice and Treatment by IFNa Prevents This Effect

Caroline Marty, PhD, Catherine Lacout, Marie Cuingnet, MD, Salma Hasan, Eric Solary, MD, PhD, William Vainchenker, MD, PhD, Jean-Luc Villeval, PhD

Blood (2011) 118 (21): 616.

https://doi.org/10.1182/blood.V118.21.616.616

Published: 2011

Journal Articles

Platelet Phenotype and Thrombosis In JAK2 V617F Mice

Lamia Lamrani, Catherine Lacout, Veronique Ollivier, Benoit HO Tin Hoe, William Vainchenker, MD, PhD, Jean-Luc Villeval, PhD, Martine Jandrot-Perrus

Blood (2011) 118 (21): 618.

https://doi.org/10.1182/blood.V118.21.618.618

Published: 2011

Journal Articles

A major role of TGF-β1 in the homing capacities of murine hematopoietic stem cell/progenitors

Claude Capron, Catherine Lacout, Yann Lécluse, Valérie Jalbert, Hédia Chagraoui, Sabine Charrier, Anne Galy, Annelise Bennaceur-Griscelli, Elisabeth Cramer-Bordé, William Vainchenker

Blood (2010) 116 (8): 1244–1253.

https://doi.org/10.1182/blood-2009-05-221093

Published: 2010

Includes: Supplemental data

Journal Articles

Myeloproliferative neoplasm induced by constitutive expression of JAK2 V617F in knock-in mice

Caroline Marty, Catherine Lacout, Antoine Martin, Salma Hasan, Sylvie Jacquot, Marie-Christine Birling, William Vainchenker, Jean-Luc Villeval

Blood (2010) 116 (5): 783–787.

https://doi.org/10.1182/blood-2009-12-257063

Published: 2010

Includes: Supplemental data

Journal Articles

Constitutive Heterozygous Expression of JAK2V617F Mutated Kinase Triggers Severe Myeloproliferative Disorder in Knock-in Mice.

Caroline Marty, Catherine Lacout, Linda Fong, Antoine Martin, William Vainchenker, MD, PhD, Jean-Luc Villeval

Blood (2009) 114 (22): 2902.

https://doi.org/10.1182/blood.V114.22.2902.2902

Published: 2009

Journal Articles

Interferon-Alpha Preferentially Targets JAK2V617F-Positive Rather Than Wild-Type Early Progenitor Cells in Myeloproliferative Disorders.

Florence Pasquier, Carole Tonetti, Rodolphe Besancenot, Bruno Cassinat, Pharm.D, Jean-Jacques Kiladjian, MD, PhD, Olivier Herault, MD, PhD, MSc, Philippe Rameau, Catherine Lacout, Jean-Luc Villeval, William Vainchenker, MD, PhD, Ronan Chaligné, Stephane Giraudier

Blood (2009) 114 (22): 436.

https://doi.org/10.1182/blood.V114.22.436.436

Published: 2009

Journal Articles

Constitutive TGF-β1 Deficiency Induces a Defect in Hematopoietic Stem/Progenitor Cell Compartment in Fetus and Neonate.

Claude Capron, Catherine Lacout, Yann Lecluse, Valérie Jalbert, Elisabeth Cramer Bordé, Anne Galy, Sabine Charrier, William Vainchenker

Blood (2008) 112 (11): 1397.

https://doi.org/10.1182/blood.V112.11.1397.1397

Published: 2008

Journal Articles

Impaired Erythropoiesis in LYL-1 Deficient Mice.

Claude Capron, Catherine Lacout, Yann Lecluse, Orianne Wagner-Ballon, Anna Lila Kaushik, Elisabeth Cramer Bordé, Fred Sablitzky, Dominique Duménil, William Vainchenker

Blood (2008) 112 (11): 1412.

https://doi.org/10.1182/blood.V112.11.1412.1412

Published: 2008

Journal Articles

Ligand-Independent MPL W515L Activity Requires Cell Surface Localization

Caroline Marty, Ronan Chaligné, Catherine Lacout, Stefan N. Constantinescu, William Vainchenker, Jean-Luc Villeval

Blood (2008) 112 (11): 2891.

https://doi.org/10.1182/blood.V112.11.2891.2891

Published: 2008

Journal Articles

P19 INK4D links endomitotic arrest and megakaryocyte maturation and is regulated by AML-1

Laure Gilles, Romain Guièze, Dominique Bluteau, Véronique Cordette-Lagarde, Catherine Lacout, Rémi Favier, Fréderic Larbret, Najet Debili, William Vainchenker, Hana Raslova

Blood (2008) 111 (8): 4081–4091.

https://doi.org/10.1182/blood-2007-09-113266

Published: 2008

Includes: Supplemental data

NARROW

SRSF2-P95Hdelays Myelofibrosis Development through Altered JAK/STAT Signaling in JAK2-V617F Megakaryocytes

Modeling the Behavior of Hematopoietic Compartments from Stem to Red Cells in Murine Steady State and Stress Hematopoiesis

MIR150 Is Involved in the Monocyte Subset Differentiation and Its Down-Regulation Leads to Classical Monocyte Accumulation in Chronic Myelomonocytic Leukemia

HSP27: A Therapeutic Target in Myelofibrosis

JAK2 and MPL protein levels determine TPO-induced megakaryocyte proliferation vs differentiation

Hemostatic disorders in a JAK2 V617F -driven mouse model of myeloproliferative neoplasm

Effect Of The JAK1/2 Inhibitor GS-0387 (momelotinib) On The Anemia Associated With a Preclinical Murine Model Of Human Primary Myelofibrosis

Use Of 46/1 Haplotype Permits To Follow JAK2 V617F Clonal Architecture In PV Patients: Clonal Evolution and Impact Of IFNα Treatment

JAK2 V617F expression in mice amplifies early hematopoietic cells and gives them a competitive advantage that is hampered by IFNα

46/1 Haplotype Permits to Follow JAK2 Homologous Recombination: Modeling JAK2 V617F clonal Architecture in PV Patients

JAK2 V617F Promotes Stem Cell Amplification Driving MPN Clonal Dominance in Mice and Treatment by IFNa Prevents This Effect

Platelet Phenotype and Thrombosis In JAK2 V617F Mice

A major role of TGF-β1 in the homing capacities of murine hematopoietic stem cell/progenitors

Myeloproliferative neoplasm induced by constitutive expression of JAK2 V617F in knock-in mice

Constitutive Heterozygous Expression of JAK2V617F Mutated Kinase Triggers Severe Myeloproliferative Disorder in Knock-in Mice.

Interferon-Alpha Preferentially Targets JAK2V617F-Positive Rather Than Wild-Type Early Progenitor Cells in Myeloproliferative Disorders.

Constitutive TGF-β1 Deficiency Induces a Defect in Hematopoietic Stem/Progenitor Cell Compartment in Fetus and Neonate.

Impaired Erythropoiesis in LYL-1 Deficient Mice.

Ligand-Independent MPL W515L Activity Requires Cell Surface Localization

P19 INK4D links endomitotic arrest and megakaryocyte maturation and is regulated by AML-1

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American Society of Hematology

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American Society of Hematology

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