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Journal Articles

Palbociclib Prevents CDK4/6 Dependent-Myeloproliferation and Myelofibrosis

Helene Duparc, Delphine Muller, Ileana Antony-Debre, PhD PharmD, Caroline Marty, PhD, Najet Debili, Jean-Luc Villeval, PhD, Isabelle Plo, William Vainchenker, Laure Gilles, PhD, Hana Raslova
Journal: Blood
Blood (2020) 136 (Supplement 1): 25.
https://doi.org/10.1182/blood-2020-141092
Published: 2020
Journal Articles

Defect in Ribosome Biogenesis Contributes to Impaired Megakaryopoiesis in Primary Myelofibrosis

Laure Gilles, PhD, Ahmet Dirim Arslan, PhD, Katerina Konstantinoff, Maureen McNulty, Lasho Terra, PhD, Animesh Pardanani, MBBS, PhD, Brady L Stein, MD, Isabelle Plo, William Vainchenker, MD PhD, Leonidas Platanias, Ayalew Tefferi, MD, John D Crispino, PhD
Journal: Blood
Blood (2014) 124 (21): 4585.
https://doi.org/10.1182/blood.V124.21.4585.4585
Published: 2014
Journal Articles

Aurora A Kinase Is a Novel Therapeutic Target In The Myeloproliferative Neoplasms

Qiang Jeremy Wen, PhD, MD, Benjamin Goldenson, Sebastien Malinge, PhD, Brady L Stein, MD MHS, Terra L Lasho, MT, (ASCP), Lawrence Breyfogle, Rachael Schultz, Qiong Yang, Laure gilles-Gendre, Priya Koppikar, Omar Abdel-Wahab, MD, Benjamin L. Ebert, MD, PhD, Animesh Pardanani, MBBS, PhD, Sandeep Gurbuxani, MBBS, PhD, Ross L. Levine, MD, Ann Mullally, MD, Ayalew Tefferi, MD, John D Crispino, PhD
Journal: Blood
Blood (2013) 122 (21): 109.
https://doi.org/10.1182/blood.V122.21.109.109
Published: 2013
Journal Articles

Aberrant Megakaryocyte Gene Expression Contributes to Primary Myelofibrosis.

Laure Gilles, PhD, Christy Finke, BS, Terra L Lasho, MT, (ASCP), Animesh Pardanani, MBBS, PhD, Ayalew Tefferi, MD, John Crispino, PhD
Journal: Blood
Blood (2012) 120 (21): 2867.
https://doi.org/10.1182/blood.V120.21.2867.2867
Published: 2012
Journal Articles

Dysmegakaryopoiesis of FPD/AML pedigrees with constitutional RUNX1 mutations is linked to myosin II deregulated expression

Dominique Bluteau, Ana C. Glembotsky, Anna Raimbault, Nathalie Balayn, Laure Gilles, Philippe Rameau, Paquita Nurden, Marie Christine Alessi, Najet Debili, William Vainchenker, Paula G. Heller, Remi Favier, Hana Raslova
Journal: Blood
Blood (2012) 120 (13): 2708–2718.
https://doi.org/10.1182/blood-2012-04-422337
Published: 2012
Includes: Supplemental data
Journal Articles

Down-regulation of the RUNX1-target gene NR4A3 contributes to hematopoiesis deregulation in familial platelet disorder/acute myelogenous leukemia

Dominique Bluteau, Laure Gilles, Morgane Hilpert, Iléana Antony-Debré, Chloe James, Najet Debili, Valerie Camara-Clayette, Orianne Wagner-Ballon, Veronique Cordette-Lagarde, Thomas Robert, Hugues Ripoche, Patrick Gonin, Sabina Swierczek, Josef Prchal, William Vainchenker, Remi Favier, Hana Raslova
Journal: Blood
Blood (2011) 118 (24): 6310–6320.
https://doi.org/10.1182/blood-2010-12-325555
Published: 2011
Includes: Supplemental data
Journal Articles

MAL/SRF complex is involved in platelet formation and megakaryocyte migration by regulating MYL9 (MLC2) and MMP9

Laure Gilles, Dominique Bluteau, Siham Boukour, Yunhua Chang, Yanyan Zhang, Thomas Robert, Philippe Dessen, Najet Debili, Olivier A. Bernard, William Vainchenker, Hana Raslova
Journal: Blood
Blood (2009) 114 (19): 4221–4232.
https://doi.org/10.1182/blood-2009-03-209932
Published: 2009
Includes: Supplemental data
Journal Articles

P19 INK4D links endomitotic arrest and megakaryocyte maturation and is regulated by AML-1

Laure Gilles, Romain Guièze, Dominique Bluteau, Véronique Cordette-Lagarde, Catherine Lacout, Rémi Favier, Fréderic Larbret, Najet Debili, William Vainchenker, Hana Raslova
Journal: Blood
Blood (2008) 111 (8): 4081–4091.
https://doi.org/10.1182/blood-2007-09-113266
Published: 2008
Includes: Supplemental data