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Dominique Bluteau
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Journal Articles

Clonal Hematopoiesis Driven By MDM4 Amplification Defines a Canonical Route Towards Secondary MDS/AML in Fanconi Anemia Patients

Marie Sebert, Stéphanie Gachet, Thierry Leblanc, Alix Rousseau, Olivier Bluteau, Rathana KIM, Raouf Benabelali, Flore Sicre de Fontbrune, Loïc Maillard, Carèle Fedronie, Nadia Vasquez, Yves Bertrand, Jean-Hugues Dalle, Francois Sigaux, Sylvie Chevret, Gerard Socie, Hugues de Thé, Christophe Antoniewski, Dominique Bluteau, Regis Peffault De Latour, Jean Soulier
Journal: Blood
Blood (2021) 138 (Supplement 1): 860.
https://doi.org/10.1182/blood-2021-147811
Published: 2021
Journal Articles

Activity of OTX015 (MK-8628), a BET-Bromodomain Inhibitor, in Acute Myeloid Leukemia (AML) Progenitor Cells

Louise Roulin, Ashfaq Ali, Aline Masse, Marie-Magdelaine Coudé, Dominique Bluteau, Thorsten Braun, MD PhD, Jeannig Berrou, Olivier Bluteau, Marc Delord, Maria Eugenia Riveiro, Patrice EDOUARD Herait, MD, Jean Soulier, MD PhD, André Baruchel, MD, Claude Gardin, MD, Hervé Dombret, Raphaël Itzykson, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2588.
https://doi.org/10.1182/blood.V126.23.2588.2588
Published: 2015
Journal Articles

Level of RUNX1 activity is critical for leukemic predisposition but not for thrombocytopenia

Iléana Antony-Debré, Vladimir T. Manchev, Nathalie Balayn, Dominique Bluteau, Cécile Tomowiak, Céline Legrand, Thierry Langlois, Olivia Bawa, Lucie Tosca, Gérard Tachdjian, Bruno Leheup, Najet Debili, Isabelle Plo, Jason A. Mills, Deborah L. French, Mitchell J. Weiss, Eric Solary, Remi Favier, William Vainchenker, Hana Raslova
Journal: Blood
Blood (2015) 125 (6): 930–940.
https://doi.org/10.1182/blood-2014-06-585513
Published: 2015
Includes: Supplemental data
Journal Articles

Dysmegakaryopoiesis of FPD/AML pedigrees with constitutional RUNX1 mutations is linked to myosin II deregulated expression

Dominique Bluteau, Ana C. Glembotsky, Anna Raimbault, Nathalie Balayn, Laure Gilles, Philippe Rameau, Paquita Nurden, Marie Christine Alessi, Najet Debili, William Vainchenker, Paula G. Heller, Remi Favier, Hana Raslova
Journal: Blood
Blood (2012) 120 (13): 2708–2718.
https://doi.org/10.1182/blood-2012-04-422337
Published: 2012
Includes: Supplemental data
Journal Articles

MYH10 protein expression in platelets as a biomarker of RUNX1 and FLI1 alterations

Brief Report
Iléana Antony-Debré, Dominique Bluteau, Raphael Itzykson, Véronique Baccini, Aline Renneville, Françoise Boehlen, Margot Morabito, Nathalie Droin, Caroline Deswarte, Yunhua Chang, Guy Leverger, Eric Solary, William Vainchenker, Rémi Favier, Hana Raslova
Journal: Blood
Blood (2012) 120 (13): 2719–2722.
https://doi.org/10.1182/blood-2012-04-422352
Published: 2012
Includes: Supplemental data
Journal Articles

Down-regulation of the RUNX1-target gene NR4A3 contributes to hematopoiesis deregulation in familial platelet disorder/acute myelogenous leukemia

Dominique Bluteau, Laure Gilles, Morgane Hilpert, Iléana Antony-Debré, Chloe James, Najet Debili, Valerie Camara-Clayette, Orianne Wagner-Ballon, Veronique Cordette-Lagarde, Thomas Robert, Hugues Ripoche, Patrick Gonin, Sabina Swierczek, Josef Prchal, William Vainchenker, Remi Favier, Hana Raslova
Journal: Blood
Blood (2011) 118 (24): 6310–6320.
https://doi.org/10.1182/blood-2010-12-325555
Published: 2011
Includes: Supplemental data
Journal Articles

RUNX1-Induced Silencing of Non-Muscle Myosin Iib (MYH10) Is Required for Megakaryocyte Polyploidization

Dominique Bluteau, PhD, Larissa Lordier, PhD, Iléana Antony-Debré, Abdelali Jalil, Céline Legrand, Philippe Rameau, Olivier Bluteau, PhD, Dima Jouni, Thomas Mercher, PhD, Catherine Leon, Christian Gachet, MD, PhD, Najet Debili, PhD, William Vainchenker, MD., Ph.D, Yunhua Chang, PhD, Hana Raslova, PhD
Journal: Blood
Blood (2011) 118 (21): 1308.
https://doi.org/10.1182/blood.V118.21.1308.1308
Published: 2011
Journal Articles

MAL/SRF complex is involved in platelet formation and megakaryocyte migration by regulating MYL9 (MLC2) and MMP9

Laure Gilles, Dominique Bluteau, Siham Boukour, Yunhua Chang, Yanyan Zhang, Thomas Robert, Philippe Dessen, Najet Debili, Olivier A. Bernard, William Vainchenker, Hana Raslova
Journal: Blood
Blood (2009) 114 (19): 4221–4232.
https://doi.org/10.1182/blood-2009-03-209932
Published: 2009
Includes: Supplemental data
Journal Articles

P19 INK4D links endomitotic arrest and megakaryocyte maturation and is regulated by AML-1

Laure Gilles, Romain Guièze, Dominique Bluteau, Véronique Cordette-Lagarde, Catherine Lacout, Rémi Favier, Fréderic Larbret, Najet Debili, William Vainchenker, Hana Raslova
Journal: Blood
Blood (2008) 111 (8): 4081–4091.
https://doi.org/10.1182/blood-2007-09-113266
Published: 2008
Includes: Supplemental data