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Journal Articles

Newly Identified Roles for PIEZO1 Mechanosensor in Controlling Normal Megakaryocyte Development and in Primary Myelofibrosis

Iris Karkempetzaki, Vittorio Abbonante, Catherine Leon, Nasi Huang, Christian Di Buduo, Daniele Cattaneo, Christina Ward, Shinobu Matsuura, Alessandra Iurlo, Alessandra Balduini, Katya Ravid
Journal: Blood
Blood (2023) 142 (Supplement 1): 6355.
https://doi.org/10.1182/blood-2023-180117
Published: 2023
Journal Articles

Importance of environmental stiffness for megakaryocyte differentiation and proplatelet formation

Alicia Aguilar, Fabien Pertuy, Anita Eckly, Catherine Strassel, Dominique Collin, Christian Gachet, François Lanza, Catherine Léon
Journal: Blood
Blood (2016) 128 (16): 2022–2032.
https://doi.org/10.1182/blood-2016-02-699959
Published: 2016
Includes: Supplemental data
Journal Articles

Myosin IIA is critical for organelle distribution and F-actin organization in megakaryocytes and platelets

Fabien Pertuy, Anita Eckly, Josiane Weber, Fabienne Proamer, Jean-Yves Rinckel, François Lanza, Christian Gachet, Catherine Léon
Journal: Blood
Blood (2014) 123 (8): 1261–1269.
https://doi.org/10.1182/blood-2013-06-508168
Published: 2014
Includes: Multimedia, Supplemental data
Journal Articles

Biogenesis of the demarcation membrane system (DMS) in megakaryocytes

Anita Eckly, Harry Heijnen, Fabien Pertuy, Willie Geerts, Fabienne Proamer, Jean-Yves Rinckel, Catherine Léon, François Lanza, Christian Gachet
Journal: Blood
Blood (2014) 123 (6): 921–930.
https://doi.org/10.1182/blood-2013-03-492330
Published: 2014
Includes: Multimedia, Supplemental data
Journal Articles

Megakaryocytes assemble podosomes that degrade matrix and protrude through basement membrane

Hannah Schachtner, Simon D. J. Calaminus, Amy Sinclair, James Monypenny, Michael P. Blundell, Catherine Leon, Tessa L. Holyoake, Adrian J. Thrasher, Alison M. Michie, Milica Vukovic, Christian Gachet, Gareth E. Jones, Steven G. Thomas, Steve P. Watson, Laura M. Machesky
Journal: Blood
Blood (2013) 121 (13): 2542–2552.
https://doi.org/10.1182/blood-2012-07-443457
Published: 2013
Includes: Multimedia, Supplemental data
Journal Articles

Romiplostim administration shows reduced megakaryocyte response-capacity and increased myelofibrosis in a mouse model of MYH9-RD

Catherine Léon, Katja Evert, Frank Dombrowski, Fabien Pertuy, Anita Eckly, Patricia Laeuffer, Christian Gachet, Andreas Greinacher
Journal: Blood
Blood (2012) 119 (14): 3333–3341.
https://doi.org/10.1182/blood-2011-08-373811
Published: 2012
Journal Articles

RUNX1-Induced Silencing of Non-Muscle Myosin Iib (MYH10) Is Required for Megakaryocyte Polyploidization

Dominique Bluteau, PhD, Larissa Lordier, PhD, Iléana Antony-Debré, Abdelali Jalil, Céline Legrand, Philippe Rameau, Olivier Bluteau, PhD, Dima Jouni, Thomas Mercher, PhD, Catherine Leon, Christian Gachet, MD, PhD, Najet Debili, PhD, William Vainchenker, MD., Ph.D, Yunhua Chang, PhD, Hana Raslova, PhD
Journal: Blood
Blood (2011) 118 (21): 1308.
https://doi.org/10.1182/blood.V118.21.1308.1308
Published: 2011
Journal Articles

Abnormal megakaryocyte morphology and proplatelet formation in mice with megakaryocyte-restricted MYH9 inactivation

Anita Eckly, Catherine Strassel, Monique Freund, Jean-Pierre Cazenave, François Lanza, Christian Gachet, Catherine Léon
Journal: Blood
Blood (2009) 113 (14): 3182–3189.
https://doi.org/10.1182/blood-2008-06-164061
Published: 2009
Includes: Supplemental data
Journal Articles

Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion

Catherine Léon, Anita Eckly, Béatrice Hechler, Boris Aleil, Monique Freund, Catherine Ravanat, Marie Jourdain, Christelle Nonne, Josiane Weber, Ralph Tiedt, Marie-Pierre Gratacap, Sonia Severin, Jean-Pierre Cazenave, François Lanza, Radek Skoda, Christian Gachet
Journal: Blood
Blood (2007) 110 (9): 3183–3191.
https://doi.org/10.1182/blood-2007-03-080184
Published: 2007
Includes: Multimedia, Supplemental data
Journal Articles

Platelet ADP receptors contribute to the initiation of intravascular coagulation

Catherine Leon, Meike Alex, Antje Klocke, Eberhard Morgenstern, Christine Moosbauer, Anita Eckly, Michael Spannagl, Christian Gachet, Bernd Engelmann
Journal: Blood
Blood (2004) 103 (2): 594–600.
https://doi.org/10.1182/blood-2003-05-1385
Published: 2004