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Amy Sinclair
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Journal Articles

hsa-mir183/EGR1 –mediated regulation of E2F1 is required for CML stem/progenitor cell survival

Francesca Pellicano, Laura Park, Lisa E. M. Hopcroft, Mansi M. Shah, Lorna Jackson, Mary T. Scott, Cassie J. Clarke, Amy Sinclair, Sheela A. Abraham, Alan Hair, G. Vignir Helgason, Mark Aspinall-O’Dea, Ravi Bhatia, Gustavo Leone, Kamil R. Kranc, Anthony D. Whetton, Tessa L. Holyoake
Journal: Blood
Blood (2018) 131 (14): 1532–1544.
https://doi.org/10.1182/blood-2017-05-783845
Published: 2018
Includes: Supplemental data
Journal Articles

CXCR2 and CXCL4 regulate survival and self-renewal of hematopoietic stem/progenitor cells

Amy Sinclair, Laura Park, Mansi Shah, Mark Drotar, Simon Calaminus, Lisa E. M. Hopcroft, Ross Kinstrie, Amelie V. Guitart, Karen Dunn, Sheela A. Abraham, Owen Sansom, Alison M. Michie, Laura Machesky, Kamil R. Kranc, Gerard J. Graham, Francesca Pellicano, Tessa L. Holyoake
Journal: Blood
Blood (2016) 128 (3): 371–383.
https://doi.org/10.1182/blood-2015-08-661785
Published: 2016
Includes: Supplemental data
Journal Articles

Misregulation Of The PRC2 Complex In CML Stem Cells Confers Sensitivity To An EZH2 Inhibitor

Mary T Scott, PhD, Koorosh Korfi, PhD, Paolo Gallipoli, PhD, Peter Saffrey, PhD, Heather Jorgensen, PhD, Michelle Cruz, Ashley Hamilton, PhD, Amy Sinclair, Andrew Crossan, PhD, Emmanuel Normant, PhD, Vidya Balasubramanian, Tessa L. Holyoake, PhD, David Vetrie, PhD
Journal: Blood
Blood (2013) 122 (21): 2710.
https://doi.org/10.1182/blood.V122.21.2710.2710
Published: 2013
Journal Articles

Megakaryocytes assemble podosomes that degrade matrix and protrude through basement membrane

Hannah Schachtner, Simon D. J. Calaminus, Amy Sinclair, James Monypenny, Michael P. Blundell, Catherine Leon, Tessa L. Holyoake, Adrian J. Thrasher, Alison M. Michie, Milica Vukovic, Christian Gachet, Gareth E. Jones, Steven G. Thomas, Steve P. Watson, Laura M. Machesky
Journal: Blood
Blood (2013) 121 (13): 2542–2552.
https://doi.org/10.1182/blood-2012-07-443457
Published: 2013
Includes: Multimedia, Supplemental data
Journal Articles

BMS-214662 Eliminates Quiescent and Proliferating Acute Myeloid Leukemia Cells through Activation of Protein Kinase Cβ and Enhances the Efficacy of Cytosine Arabinoside

Francesca Pellicano, PhD, Amy Sinclair, BSc, MSc, Alan Hair, BSc, PhD, Tessa L. Holyoake, PhD, FRCP, FRCPath, Mhairi Copland, PhD, BSc, MRCP, FRCPath
Journal: Blood
Blood (2010) 116 (21): 2167.
https://doi.org/10.1182/blood.V116.21.2167.2167
Published: 2010