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Journal Articles

Two Novel Compound Heterozygous Pathogenic Variants in P2YR12 gene

Arnaud Dupuis, PhD, Doris Böckelmann, PhD, Patricia Laeuffer, Katharina Neubauer, PhD, Christian Gachet, MD PhD, Barbara Zieger

Blood (2018) 132 (Supplement 1): 1154.

https://doi.org/10.1182/blood-2018-99-112833

Published: 2018

Journal Articles

Selected Expression and Functional Importance of α4a-Tubulin in Platelet Biogenesis

Catherine Strassel, PhD, Agnes Hovasse, PhD, Sylvie Moog, Bsc, Magda Mageira, PhD, Morgane Batzenschlager, PhD, Christine Schaeffer-Reiss, PhD, Benjamin Kile, PhD, Christian Gachet, MD PhD, Carsten Janke, PhD, Francois Lanza, PhD MD

Blood (2016) 128 (22): 1360.

https://doi.org/10.1182/blood.V128.22.1360.1360

Published: 2016

Journal Articles

A Potential Protective Role of Platelets during Septic Shock Does Not Depend on Their Purinergic Receptors

Beatrice Hechler, PhD, Chloé Zimmermann, MSc, Yannick Rabouel, MD, Stéphanie Magnenat, BSc, Mélanie Burban, PhD, Julie Boisramé-Helms, MD PhD, Ferhat Meziani, MD PhD, Christian Gachet, MD PhD

Blood (2016) 128 (22): 2537.

https://doi.org/10.1182/blood.V128.22.2537.2537

Published: 2016

Journal Articles

Respective contributions of single and compound granule fusion to secretion by activated platelets

Anita Eckly, Jean-Yves Rinckel, Fabienne Proamer, Neslihan Ulas, Smita Joshi, Sidney W. Whiteheart, Christian Gachet

Blood (2016) 128 (21): 2538–2549.

https://doi.org/10.1182/blood-2016-03-705681

Published: 2016

Includes: Multimedia, Supplemental data

Journal Articles

Importance of environmental stiffness for megakaryocyte differentiation and proplatelet formation

Alicia Aguilar, Fabien Pertuy, Anita Eckly, Catherine Strassel, Dominique Collin, Christian Gachet, François Lanza, Catherine Léon

Blood (2016) 128 (16): 2022–2032.

https://doi.org/10.1182/blood-2016-02-699959

Published: 2016

Includes: Supplemental data

Journal Articles

Coagulation factors bound to procoagulant platelets concentrate in cap structures to promote clotting

Nadezhda A. Podoplelova, Anastasia N. Sveshnikova, Yana N. Kotova, Anita Eckly, Nicolas Receveur, Dmitry Yu. Nechipurenko, Sergey I. Obydennyi, Igor I. Kireev, Christian Gachet, Fazly I. Ataullakhanov, Pierre H. Mangin, Mikhail A. Panteleev

Blood (2016) 128 (13): 1745–1755.

https://doi.org/10.1182/blood-2016-02-696898

Published: 2016

Includes: Multimedia, Supplemental data

Journal Articles

Aryl hydrocarbon receptor–dependent enrichment of a megakaryocytic precursor with a high potential to produce proplatelets

Catherine Strassel, Nathalie Brouard, Lea Mallo, Nicolas Receveur, Pierre Mangin, Anita Eckly, Ivan Bieche, Karin Tarte, Christian Gachet, François Lanza

Blood (2016) 127 (18): 2231–2240.

https://doi.org/10.1182/blood-2015-09-670208

Published: 2016

Includes: Supplemental data

Journal Articles

Resolving the multifaceted mechanisms of the ferric chloride thrombosis model using an interdisciplinary microfluidic approach

Jordan C. Ciciliano, Yumiko Sakurai, David R. Myers, Meredith E. Fay, Beatrice Hechler, Shannon Meeks, Renhao Li, J. Brandon Dixon, L. Andrew Lyon, Christian Gachet, Wilbur A. Lam

Blood (2015) 126 (6): 817–824.

https://doi.org/10.1182/blood-2015-02-628594

Published: 2015

Includes: Multimedia, Supplemental data

Journal Articles

Platelet glycoprotein VI binds to polymerized fibrin and promotes thrombin generation

Elmina Mammadova-Bach, Véronique Ollivier, Stéphane Loyau, Mathieu Schaff, Bénédicte Dumont, Rémi Favier, Geneviève Freyburger, Véronique Latger-Cannard, Bernhard Nieswandt, Christian Gachet, Pierre H. Mangin, Martine Jandrot-Perrus

Blood (2015) 126 (5): 683–691.

https://doi.org/10.1182/blood-2015-02-629717

Published: 2015

Includes: Multimedia, Supplemental data

Journal Articles

Identification of a new dysfunctional platelet P2Y 12 receptor variant associated with bleeding diathesis

Anna Lecchi, Cristina Razzari, Silvia Paoletta, Arnaud Dupuis, Lea Nakamura, Philippe Ohlmann, Christian Gachet, Kenneth A. Jacobson, Barbara Zieger, Marco Cattaneo

Blood (2015) 125 (6): 1006–1013.

https://doi.org/10.1182/blood-2013-07-517896

Published: 2015

Journal Articles

GPVI Interaction with Polymerized Fibrin Boosts Thrombin Generation and Thrombus Growth

Martine Jandrot-Perrus, MD PhD, Elmina Mammadova-Bach, Veronique Ollivier, PhD, Stephane Loyau, Christian Gachet, MD, Pierre H Mangin, PhD

Blood (2014) 124 (21): 4152.

https://doi.org/10.1182/blood.V124.21.4152.4152

Published: 2014

Journal Articles

Myosin IIA is critical for organelle distribution and F-actin organization in megakaryocytes and platelets

Fabien Pertuy, Anita Eckly, Josiane Weber, Fabienne Proamer, Jean-Yves Rinckel, François Lanza, Christian Gachet, Catherine Léon

Blood (2014) 123 (8): 1261–1269.

https://doi.org/10.1182/blood-2013-06-508168

Published: 2014

Includes: Multimedia, Supplemental data

Journal Articles

Biogenesis of the demarcation membrane system (DMS) in megakaryocytes

Anita Eckly, Harry Heijnen, Fabien Pertuy, Willie Geerts, Fabienne Proamer, Jean-Yves Rinckel, Catherine Léon, François Lanza, Christian Gachet

Blood (2014) 123 (6): 921–930.

https://doi.org/10.1182/blood-2013-03-492330

Published: 2014

Includes: Multimedia, Supplemental data

Journal Articles

Defective tubulin organization and proplatelet formation in murine megakaryocytes lacking Rac1 and Cdc42

Irina Pleines, Sebastian Dütting, Deya Cherpokova, Anita Eckly, Imke Meyer, Martina Morowski, Georg Krohne, Harald Schulze, Christian Gachet, Najet Debili, Cord Brakebusch, Bernhard Nieswandt

Blood (2013) 122 (18): 3178–3187.

https://doi.org/10.1182/blood-2013-03-487942

Published: 2013

Includes: Supplemental data

Journal Articles

Megakaryocytes assemble podosomes that degrade matrix and protrude through basement membrane

Hannah Schachtner, Simon D. J. Calaminus, Amy Sinclair, James Monypenny, Michael P. Blundell, Catherine Leon, Tessa L. Holyoake, Adrian J. Thrasher, Alison M. Michie, Milica Vukovic, Christian Gachet, Gareth E. Jones, Steven G. Thomas, Steve P. Watson, Laura M. Machesky

Blood (2013) 121 (13): 2542–2552.

https://doi.org/10.1182/blood-2012-07-443457

Published: 2013

Includes: Multimedia, Supplemental data

Journal Articles

Romiplostim administration shows reduced megakaryocyte response-capacity and increased myelofibrosis in a mouse model of MYH9-RD

Catherine Léon, Katja Evert, Frank Dombrowski, Fabien Pertuy, Anita Eckly, Patricia Laeuffer, Christian Gachet, Andreas Greinacher

Blood (2012) 119 (14): 3333–3341.

https://doi.org/10.1182/blood-2011-08-373811

Published: 2012

Journal Articles

RUNX1-Induced Silencing of Non-Muscle Myosin Iib (MYH10) Is Required for Megakaryocyte Polyploidization

Dominique Bluteau, PhD, Larissa Lordier, PhD, Iléana Antony-Debré, Abdelali Jalil, Céline Legrand, Philippe Rameau, Olivier Bluteau, PhD, Dima Jouni, Thomas Mercher, PhD, Catherine Leon, Christian Gachet, MD, PhD, Najet Debili, PhD, William Vainchenker, MD., Ph.D, Yunhua Chang, PhD, Hana Raslova, PhD

Blood (2011) 118 (21): 1308.

https://doi.org/10.1182/blood.V118.21.1308.1308

Published: 2011

Journal Articles

ADF/n-cofilin–dependent actin turnover determines platelet formation and sizing

Markus Bender, Anita Eckly, John H. Hartwig, Margitta Elvers, Irina Pleines, Shuchi Gupta, Georg Krohne, Elisabeth Jeanclos, Antje Gohla, Christine Gurniak, Christian Gachet, Walter Witke, Bernhard Nieswandt

Blood (2010) 116 (10): 1767–1775.

https://doi.org/10.1182/blood-2010-03-274340

Published: 2010

Includes: Multimedia, Supplemental data

Journal Articles

A central role of GPIb-IX in the procoagulant function of platelets that is independent of the 45-kDa GPIbα N-terminal extracellular domain

Catherine Ravanat, Catherine Strassel, Béatrice Hechler, Simone Schuhler, Gaëtan Chicanne, Bernard Payrastre, Christian Gachet, François Lanza

Blood (2010) 116 (7): 1157–1164.

https://doi.org/10.1182/blood-2010-01-266080

Published: 2010

Includes: Supplemental data

Journal Articles

Multiple alterations of platelet functions dominated by increased secretion in mice lacking Cdc42 in platelets

Irina Pleines, Anita Eckly, Margitta Elvers, Ina Hagedorn, Sandra Eliautou, Markus Bender, Xunwei Wu, Francois Lanza, Christian Gachet, Cord Brakebusch, Bernhard Nieswandt

Blood (2010) 115 (16): 3364–3373.

https://doi.org/10.1182/blood-2009-09-242271

Published: 2010

NARROW

Two Novel Compound Heterozygous Pathogenic Variants in P2YR12 gene

Selected Expression and Functional Importance of α4a-Tubulin in Platelet Biogenesis

A Potential Protective Role of Platelets during Septic Shock Does Not Depend on Their Purinergic Receptors

Respective contributions of single and compound granule fusion to secretion by activated platelets

Importance of environmental stiffness for megakaryocyte differentiation and proplatelet formation

Coagulation factors bound to procoagulant platelets concentrate in cap structures to promote clotting

Aryl hydrocarbon receptor–dependent enrichment of a megakaryocytic precursor with a high potential to produce proplatelets

Resolving the multifaceted mechanisms of the ferric chloride thrombosis model using an interdisciplinary microfluidic approach

Platelet glycoprotein VI binds to polymerized fibrin and promotes thrombin generation

Identification of a new dysfunctional platelet P2Y 12 receptor variant associated with bleeding diathesis

GPVI Interaction with Polymerized Fibrin Boosts Thrombin Generation and Thrombus Growth

Myosin IIA is critical for organelle distribution and F-actin organization in megakaryocytes and platelets

Biogenesis of the demarcation membrane system (DMS) in megakaryocytes

Defective tubulin organization and proplatelet formation in murine megakaryocytes lacking Rac1 and Cdc42

Megakaryocytes assemble podosomes that degrade matrix and protrude through basement membrane

Romiplostim administration shows reduced megakaryocyte response-capacity and increased myelofibrosis in a mouse model of MYH9-RD

RUNX1-Induced Silencing of Non-Muscle Myosin Iib (MYH10) Is Required for Megakaryocyte Polyploidization

ADF/n-cofilin–dependent actin turnover determines platelet formation and sizing

A central role of GPIb-IX in the procoagulant function of platelets that is independent of the 45-kDa GPIbα N-terminal extracellular domain

Multiple alterations of platelet functions dominated by increased secretion in mice lacking Cdc42 in platelets

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American Society of Hematology

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American Society of Hematology

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