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Journal Articles

Novel inhibitors of the histone methyltransferase DOT1L show potent antileukemic activity in patient-derived xenografts

Florian Perner, Jayant Y. Gadrey, Yijun Xiong, Charles Hatton, Benjamin K. Eschle, Andreas Weiss, Frédéric Stauffer, Christoph Gaul, Ralph Tiedt, Jennifer A. Perry, Scott A. Armstrong, Andrei V. Krivtsov

Blood (2020) 136 (17): 1983–1988.

https://doi.org/10.1182/blood.2020006113

Published: 2020

Includes: Supplemental data

Journal Articles

Pronounced thrombocytosis in transgenic mice expressing reduced levels of Mpl in platelets and terminally differentiated megakaryocytes

Ralph Tiedt, Jörn Coers, Sandra Ziegler, Adrian Wiestner, Hui Hao-Shen, Caroline Bornmann, Johannes Schenkel, Svetlana Karakhanova, Frederic J. de Sauvage, Carl W. Jackson, Radek C. Skoda

Blood (2009) 113 (8): 1768–1777.

https://doi.org/10.1182/blood-2008-03-146084

Published: 2009

Journal Articles

Ratio of mutant JAK2 -V617F to wild-type Jak2 determines the MPD phenotypes in transgenic mice

Ralph Tiedt, Hui Hao-Shen, Marta A. Sobas, Renate Looser, Stephan Dirnhofer, Jürg Schwaller, Radek C. Skoda

Blood (2008) 111 (8): 3931–3940.

https://doi.org/10.1182/blood-2007-08-107748

Published: 2008

Includes: Supplemental data

Journal Articles

Characterization of del20q in Peripheral Blood of MPD Patients Using Copy Number Analysis and High Resolution Oligonucleotide CGH Array

Franz Schaub, MSc, Ralph Tiedt, PhD, Sylvie Hermouet, MD, François Girodon, MD, Robert Kralovics, PhD, André Tichelli, MD, Radek C. Skoda, MD

Blood (2007) 110 (11): 1530.

https://doi.org/10.1182/blood.V110.11.1530.1530

Published: 2007

Journal Articles

Ratio of Mutant JAK2-V617F to Wild Type Jak2 Determines the MPD Phenotypes in Transgenic Mice.

Ralph Tiedt, PhD, Hui Hao-Shen, MSc, Marta A. Sobas, MD, Renate Looser, Stephan Dirnhofer, MD, Jürg Schwaller, MD, Radek C. Skoda, MD

Blood (2007) 110 (11): 674.

https://doi.org/10.1182/blood.V110.11.674.674

Published: 2007

Journal Articles

Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion

Catherine Léon, Anita Eckly, Béatrice Hechler, Boris Aleil, Monique Freund, Catherine Ravanat, Marie Jourdain, Christelle Nonne, Josiane Weber, Ralph Tiedt, Marie-Pierre Gratacap, Sonia Severin, Jean-Pierre Cazenave, François Lanza, Radek Skoda, Christian Gachet

Blood (2007) 110 (9): 3183–3191.

https://doi.org/10.1182/blood-2007-03-080184

Published: 2007

Includes: Multimedia, Supplemental data

Journal Articles

Focal Adhesion Kinase in Megakaryopoiesis: A Study of Megakaryocyte-Specific FAK Deletion.

Ian S. Hitchcock, PhD, Norma E. Fox, Katherine Sear, Ralph Tiedt, Radek Skoda, Kenneth Kaushansky

Blood (2006) 108 (11): 354.

https://doi.org/10.1182/blood.V108.11.354.354

Published: 2006

Journal Articles

A Transgenic Mouse Model To Study JAK2-V617F In Vivo .

Ralph Tiedt, Hui Hao-Shen, Radek C. Skoda

Blood (2006) 108 (11): 665.

https://doi.org/10.1182/blood.V108.11.665.665

Published: 2006

Journal Articles

Pf4-Cre transgenic mice allow the generation of lineage-restricted gene knockouts for studying megakaryocyte and platelet function in vivo

Ralph Tiedt, Tibor Schomber, Hui Hao-Shen, Radek C. Skoda

Blood (2006) 109 (4): 1503–1506.

https://doi.org/10.1182/blood-2006-04-020362

Published: 2006

Includes: Supplemental data

Journal Articles

Altered gene expression in myeloproliferative disorders correlates with activation of signaling by the V617F mutation of Jak2

Robert Kralovics, Soon-Siong Teo, Andreas S. Buser, Martin Brutsche, Ralph Tiedt, Andre Tichelli, Francesco Passamonti, Daniela Pietra, Mario Cazzola, Radek C. Skoda

Blood (2005) 106 (10): 3374–3376.

https://doi.org/10.1182/blood-2005-05-1889

Published: 2005

Includes: Supplemental data

NARROW

Novel inhibitors of the histone methyltransferase DOT1L show potent antileukemic activity in patient-derived xenografts

Pronounced thrombocytosis in transgenic mice expressing reduced levels of Mpl in platelets and terminally differentiated megakaryocytes

Ratio of mutant JAK2 -V617F to wild-type Jak2 determines the MPD phenotypes in transgenic mice

Characterization of del20q in Peripheral Blood of MPD Patients Using Copy Number Analysis and High Resolution Oligonucleotide CGH Array

Ratio of Mutant JAK2-V617F to Wild Type Jak2 Determines the MPD Phenotypes in Transgenic Mice.

Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion

Focal Adhesion Kinase in Megakaryopoiesis: A Study of Megakaryocyte-Specific FAK Deletion.

A Transgenic Mouse Model To Study JAK2-V617F In Vivo .

Pf4-Cre transgenic mice allow the generation of lineage-restricted gene knockouts for studying megakaryocyte and platelet function in vivo

Altered gene expression in myeloproliferative disorders correlates with activation of signaling by the V617F mutation of Jak2

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American Society of Hematology

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American Society of Hematology

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