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Nathalie Droin
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Journal Articles

Mutational Profile and Dynamics of PPM1D -Mutant Clones in the Spectrum of Myeloid Disorders

Jean Pegliasco, David Fandrei, Florence Pasquier, Nathalie Ibrahim, Maria Kfoury, Guillemette Imbert-De-Tremiolles, Nourhan Lizziek, Céline Berthon, Mael Heiblig, Delphine Lebon, Ambroise Marcais, Mathieu Meunier, Ahmad Aljijakli, Emilie Lemasle, Sylvain Chantepie, Cécile Pautas, Pierre-Yves Dumas, Stephanie Haiat, Cyril Quivoron, Ileana antony-Debre, Sophie Cotteret, Raphael Itzykson, Hervé Dombret, Nicolas Duployez, Nathalie Droin, Christophe Marzac, Elsa Bernard, Jean-Baptiste Micol
Journal: Blood
Blood (2023) 142 (Supplement 1): 4064.
https://doi.org/10.1182/blood-2023-189428
Published: 2023
Journal Articles

Structural variation cooperates with permissive chromatin to control enhancer hijacking–mediated oncogenic transcription

Giovanni A. Botten, Yuannyu Zhang, Kseniia Dudnyk, Yoon Jung Kim, Xin Liu, Jacob T. Sanders, Aygun Imanci, Nathalie Droin, Hui Cao, Pranita Kaphle, Kathryn E. Dickerson, Kirthi R. Kumar, Mingyi Chen, Weina Chen, Eric Solary, Peter Ly, Jian Zhou, Jian Xu
Journal: Blood
Blood (2023) 142 (4): 336–351.
https://doi.org/10.1182/blood.2022017555
Published: 2023
Includes: Supplemental data
Journal Articles

Structural Variation Cooperates with Permissive Chromatin to Control Enhancer Hijacking-Mediated Oncogenic Transcription

Giovanni A. Botten, Yuannyu Zhang, Kseniia Dudnyk, Xin Liu, Jacob T. Sanders, Aygun Imanci, Nathalie Droin, Hui Cao, Pranita Kaphle, Kathryn E. Dickerson, Mingyi Chen, Weina Chen, Eric Solary, Peter Ly, Jian Zhou, Jian Xu
Journal: Blood
Blood (2022) 140 (Supplement 1): 1007–1008.
https://doi.org/10.1182/blood-2022-169565
Published: 2022
Journal Articles

DNA Replication Stress Due to Loss of R-Loops in Myelodysplastic Syndromes with SF3B1 Mutation

David Rombaut, Carine Lefevre, Batoul Farhat, Sabrina Bondu, Anne Letessier, Auriane Lesieur-Pasquier, Daisy Castillo-Guzman, Marjorie Leduc, Emilie-Fleur Gautier, Virginie Chesnais, Alice Rousseau, Ismael Boussaid, Sarah Battault, Alexandre Houy, Didier Bouscary, Lise Willems, Nicolas Chapuis, Sophie Park, Sophie Raynaud, Thomas Cluzeau, Emmanuelle Clappier, Pierre Fenaux, Lionel Ades, Eric Solary, Raphael Margueron, Michel Wassef, Olivier Kosmider, Samar Alsafadi, Nathalie Droin, Angelos Constantinou, Marc-Henri Stern, Benoit Miotto, Frederic Chedin, Michaela Fontenay
Journal: Blood
Blood (2022) 140 (Supplement 1): 215–216.
https://doi.org/10.1182/blood-2022-164584
Published: 2022
Journal Articles

Asxl1 loss cooperates with oncogenic Nras in mice to reprogram the immune microenvironment and drive leukemic transformation

Xiaona You, Fabao Liu, Moritz Binder, Alexis Vedder, Terra Lasho, Zhi Wen, Xin Gao, Evan Flietner, Adhithi Rajagopalan, Yun Zhou, Christy Finke, Abhishek Mangaonkar, Ruiqi Liao, Guangyao Kong, Erik A. Ranheim, Nathalie Droin, Anthony M. Hunter, Sergey Nikolaev, Maria Balasis, Omar Abdel-Wahab, Ross L. Levine, Britta Will, Kalyan Vara Ganesh Nadiminti, David Yang, Klaus Geissler, Eric Solary, Wei Xu, Eric Padron, Mrinal M. Patnaik, Jing Zhang
Journal: Blood
Blood (2022) 139 (7): 1066–1079.
https://doi.org/10.1182/blood.2021012519
Published: 2022
Includes: Supplemental data
Journal Articles

SRSF2-P95Hdelays Myelofibrosis Development through Altered JAK/STAT Signaling in JAK2-V617F Megakaryocytes

Christophe Willekens, Lucie Laplane, Tracy Dagher, Camélia Benlabiod, Catherine Lacout, Philippe Rameau, Cyril Catelain, Alexia Alfaro, Valérie Edmond, Nicolas Signolle, Aymeric Silvin, Florent Ginhoux, Valentine Marchand, Nathalie Droin, Remco Hoogenboezem, Rebekka K. Schneider, Alexander V Penson, Omar Abdel-Wahab, Patrick Gonin, Caroline Marty, Isabelle Plo, Jean-Luc Villeval, Francoise Porteu, William Vainchenker, Eric Solary
Journal: Blood
Blood (2021) 138 (Supplement 1): 2544.
https://doi.org/10.1182/blood-2021-149757
Published: 2021
Journal Articles

Cytokine-like protein 1–induced survival of monocytes suggests a combined strategy targeting MCL1 and MAPK in CMML

Margaux Sevin, Franck Debeurme, Lucie Laplane, Séverine Badel, Margot Morabito, Hanna L. Newman, Miguel Torres-Martin, Qin Yang, Bouchra Badaoui, Orianne Wagner-Ballon, Véronique Saada, Dorothée Sélimoglu-Buet, Laurence Kraus-Berthier, Sébastien Banquet, Alix Derreal, Pierre Fenaux, Raphael Itzykson, Thorsten Braun, Gabriel Etienne, Celine Berthon, Sylvain Thépot, Oliver Kepp, Guido Kroemer, Eric Padron, Maria E. Figueroa, Nathalie Droin, Eric Solary
Journal: Blood
Blood (2021) 137 (24): 3390–3402.
https://doi.org/10.1182/blood.2020008729
Published: 2021
Includes: Supplemental data
Journal Articles

Eltrombopag in Chronic Myelomonocytic Leukemia (CMML) with Severe Thrombocytopenia: Final Results of a Multicenter Phase II Study

Florence Rabian, MD, Jérôme Lambert, Daniela Barbieri, Berengere Gruson, MD, Sylvain Thepot, MD, Thorsten Braun, MD PhD, Norbert Vey, MD, Jacques Delaunay, MD, Laurence Legros, PhD MD, Julie Lejeune, Anouk Walter-petrich, Rosa Sapena, Nathalie Droin, PhD, Fatiha Chermat, Francoise Porteu, Daniel Lusina, Lionel Ades, MDPhD, Eric Solary, MD PhD, Pierre Fenaux, MDPhD, Raphael Itzykson, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 15–16.
https://doi.org/10.1182/blood-2020-137469
Published: 2020
Journal Articles

Decitabine Versus Hydroxyurea for Advanced Proliferative CMML: Results of the Emsco Randomized Phase 3 Dacota Trial

Raphael Itzykson, MD PhD, Valeria Santini, Cendrine Chaffaut, Ades Lionel, Sylvain Thepot, MD, Aristoteles Giagounidis, Margot Morabito, Nathalie Droin, Michael Luebbert, Rosa Sapena, Stanislas Nimubona, MD, Jean E. Goasguen, MD PhD, Eric Wattel, MD PhD, Gina Zini, MDPhD, Jose Miguel Torregrosa Diaz, Ulrich Germing, Anna Maria Pelizzari, Sophie Park, MD PhD, Nadja Jaekel, Georgia Metzgeroth, Francesco Onida, MD, Robert Navarro, Andrea Patriarca, MD, Aspasia Stamatoulas Bastard, MD, Martin Puttrich, Sandra Mossuto, Eric Solary, MD PhD, Silke Gloaguen, Msc, Sylvie Chevret, MD PhD, Fatiha Chermat, Uwe Platzbecker, Pierre Fenaux, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 53–54.
https://doi.org/10.1182/blood-2020-138680
Published: 2020
Journal Articles

Genetic characterization of B-cell prolymphocytic leukemia: a prognostic model involving MYC and TP53

CME
Elise Chapiro, Elodie Pramil, M’boyba Diop, Damien Roos-Weil, Clémentine Dillard, Clémentine Gabillaud, Karim Maloum, Catherine Settegrana, Lucile Baseggio, Jean-François Lesesve, Mélanie Yon, Ludovic Jondreville, Claude Lesty, Frédéric Davi, Magali Le Garff-Tavernier, Nathalie Droin, Philippe Dessen, Caroline Algrin, Véronique Leblond, Jean Gabarre, Simon Bouzy, Virginie Eclache, Baptiste Gaillard, Evelyne Callet-Bauchu, Marc Muller, Christine Lefebvre, Nathalie Nadal, Antoine Ittel, Stéphanie Struski, Marie-Agnès Collonge-Rame, Benoit Quilichini, Sandra Fert-Ferrer, Nathalie Auger, Isabelle Radford-Weiss, Lena Wagner, Sebastian Scheinost, Thorsten Zenz, Santos A. Susin, Olivier A. Bernard, Florence Nguyen-Khac
Journal: Blood
Blood (2019) 134 (21): 1821–1831.
https://doi.org/10.1182/blood.2019001187
Published: 2019
Includes: Supplemental data
Journal Articles

Depletion of the Long Non-Coding RNA MALAT1 primes Chronic Myelomonocytic Leukemia (CMML) for Differentiation Therapy with All- Trans retinoic Acid (ATRA) through the Transcription Factor CREB

Maria E Balasis, Alexis Vedder, BS, Lei Sun, Ariel Quintana, PhD, Abhishek Dhawan, Hannah Newman, BS, Jane Merlevede, Kathy McGraw, PhD, Traci Kruer, PhD, Nana Ben-Crentsil, Jeffrey S Painter, BS, Nathalie Droin, PhD, Thomas Cluzeau, MD PhD, Christopher Letson, BS, Sheng Wei, MD, Rami S. Komrokji, MD, Hailing Zhang, MD, A. Robert MacLeod, PhD, Alan F. List, MD, Eric Solary, MD PhD, Pearlie K. Epling-Burnette, Eric Padron, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1692.
https://doi.org/10.1182/blood-2019-128573
Published: 2019
Journal Articles

Peripheral Blood Cell Sorting Strategies for Transcriptomic Analysis in Chronic Myelomonocytic Leukemia

Moritz Binder, MDMPH, Ryan Carr, MD PhD, Nathalie Droin, PhD, Abhishek A Mangaonkar, MBBS, Giacomo Coltro, MD, Luciana L Almada, PhD, David Marks, PhD, Kurt Berger, Terra Lasho, PhD, Naseema Gangat, MBBS, Christopher Pin, PhD, Martin Fernandez-Zapico, MD, Eric Solary, MD PhD, Mrinal M Patnaik, MDMBBS
Journal: Blood
Blood (2019) 134 (Supplement_1): 4232.
https://doi.org/10.1182/blood-2019-122187
Published: 2019
Journal Articles

Familial predisposition to TP53/complex karyotype MDS and leukemia in DNA repair-deficient xeroderma pigmentosum

Alain Sarasin, Samuel Quentin, Nathalie Droin, Mourad Sahbatou, Véronique Saada, Nathalie Auger, Yannick Boursin, Philippe Dessen, Anna Raimbault, Vahid Asnafi, Jean-Luc Schmutz, Alain Taïeb, Carlos F. M. Menck, Filippo Rosselli, Laurianne Drieu La Rochelle, Caroline Robert, Flore Sicre de Fontbrune, Marie Sébert, Thierry Leblanc, Patricia Kannouche, Stéphane De Botton, Eric Solary, Jean Soulier
Journal: Blood
Blood (2019) 133 (25): 2718–2724.
https://doi.org/10.1182/blood-2019-01-895698
Published: 2019
Includes: Supplemental data
Journal Articles

A Phase II Trial of Eltrombopag in Chronic Myelomonocytic Leukemia (CMML) with Thrombocytopenia

Raphael Itzykson, MD PhD, Jérôme Lambert, MDPhD, Daniela Barbieri, Berengere Gruson, Sylvain Thepot, MD, Thorsten Braun, MD PhD, Norbert Vey, Jacques Delaunay, MD, Laurence Legros, MD PhD, Julie Lejeune, Rosa Sapena, Nathalie Droin, Francoise Porteu, Eric Solary, MD, Pierre Fenaux, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4266.
https://doi.org/10.1182/blood.V130.Suppl_1.4266.4266
Published: 2017
Journal Articles

Prognostic Role of Gene Mutations in Chronic Myelomonocytic Leukemia (CMML) Patients Treated with Hypomethylating Agents. a Report on 183 Patients

Matthieu Duchmann, Fevzi Yalniz, MD, Alessandro Sanna, David A Sallman, MD, Catherine C. Coombs, MD, Aline Renneville, MDPhD, Olivier Kosmider, Thorsten Braun, MD PhD, Uwe Platzbecker, MD, Lise Willems, MD, Lionel Ades, MD PhD, Michaela Fontenay, MD PhD, Raajit K. Rampal, MD PhD, Eric Padron, MD, Nathalie Droin, Claude Preudhomme, PharmD, PhD, Valeria Santini, MD, Mrinal M. Patnaik, MDMBBS, Pierre Fenaux, MD PhD, Éric Solary, MD PhD, Raphael Itzykson, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 159.
https://doi.org/10.1182/blood.V130.Suppl_1.159.159
Published: 2017
Journal Articles

High prevalence of myeloid neoplasms in adults with non–Langerhans cell histiocytosis

Matthias Papo, Eli L. Diamond, Fleur Cohen-Aubart, Jean-François Emile, Damien Roos-Weil, Nishant Gupta, Benjamin H. Durham, Neval Ozkaya, Ahmet Dogan, Gary A. Ulaner, Raajit Rampal, Jean-Emmanuel Kahn, Thomas Sené, Frédéric Charlotte, Baptiste Hervier, Caroline Besnard, Olivier A. Bernard, Catherine Settegrana, Nathalie Droin, Zofia Hélias-Rodzewicz, Zahir Amoura, Omar Abdel-Wahab, Julien Haroche
Journal: Blood
Blood (2017) 130 (8): 1007–1013.
https://doi.org/10.1182/blood-2017-01-761718
Published: 2017
Includes: Supplemental data
Journal Articles

Accumulation of classical monocytes defines a subgroup of MDS that frequently evolves into CMML

Dorothée Selimoglu-Buet, Bouchra Badaoui, Emmanuel Benayoun, Andréa Toma, Pierre Fenaux, Bruno Quesnel, Gabriel Etienne, Thorsten Braun, Nassera Abermil, Margot Morabito, Nathalie Droin, Eric Solary, Orianne Wagner-Ballon
Journal: Blood
Blood (2017) 130 (6): 832–835.
https://doi.org/10.1182/blood-2017-04-779579
Published: 2017
Journal Articles

Presence of atypical thrombopoietin receptor (MPL) mutations in triple-negative essential thrombocythemia patients

Xénia Cabagnols, Fabrizia Favale, Florence Pasquier, Kahia Messaoudi, Jean Philippe Defour, Jean Christophe Ianotto, Christophe Marzac, Jean Pierre Le Couédic, Nathalie Droin, Ilyas Chachoua, Remi Favier, M’boyba Khadija Diop, Valérie Ugo, Nicole Casadevall, Najet Debili, Hana Raslova, Christine Bellanné-Chantelot, Stefan N. Constantinescu, Olivier Bluteau, Isabelle Plo, William Vainchenker
Journal: Blood
Blood (2016) 127 (3): 333–342.
https://doi.org/10.1182/blood-2015-07-661983
Published: 2016
Includes: Supplemental data
Journal Articles

Characteristic repartition of monocyte subsets as a diagnostic signature of chronic myelomonocytic leukemia

Dorothée Selimoglu-Buet, Orianne Wagner-Ballon, Véronique Saada, Valérie Bardet, Raphaël Itzykson, Laura Bencheikh, Margot Morabito, Elisabeth Met, Camille Debord, Emmanuel Benayoun, Anne-Marie Nloga, Pierre Fenaux, Thorsten Braun, Christophe Willekens, Bruno Quesnel, Lionel Adès, Michaela Fontenay, Philippe Rameau, Nathalie Droin, Serge Koscielny, Eric Solary
Journal: Blood
Blood (2015) 125 (23): 3618–3626.
https://doi.org/10.1182/blood-2015-01-620781
Published: 2015
Includes: Supplemental data
Journal Articles

The P2Y6-AMPK Pathway Triggers Autophagy during CSF-1-Induced Human Monocyte Differentiation and Is a Potential Target in CMML

Sandrine Obba, PhDstudent, Zoheir Hizir, PhDstudent, Dorothée Selimoglu-Buet, PhD, Laurent Boyer, PhD, Anja Pfeifer, PhD, Mohamed-Amine Hamouda, PhDstudent, Diogo Goncalves, Michael Cerezo, PhDstudent, Sandrine Marchetti, PhD, Stephane Rocchi, PhD, Nathalie Droin, PhD, Guillaume Robert, PhD, Frederic Luciano, PhD, Bernard Robaye, PhD, Benoit Viollet, PhD, Laurence Legros, MD PhD, Eric Solary, MD PhD, Patrick Auberger, PhD, Arnaud Jacquel, PhD
Journal: Blood
Blood (2014) 124 (21): 4347.
https://doi.org/10.1182/blood.V124.21.4347.4347
Published: 2014