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Journal Articles

Applying Machine Learning to Support Early Diagnosis of Light-Chain Amyloidosis: A Combination of Knowledge-Based Approach with Data-Driven Approach

Yang Liu, Xuelin Dou, Lei Wen, Xin Gao, Xiaohong Wang, Jin Lu
Journal: Blood
Blood (2023) 142 (Supplement 1): 2038.
https://doi.org/10.1182/blood-2023-174001
Published: 2023
Journal Articles

Identification of Therapy-Induced Clonal Evolution and Resistance Pathways in MRD Clones in Multiple Myeloma through Single-Cell Sequencing

Jian Cui, Xiaoyun Li, Shuhui Deng, Lugui Qiu, Xin Gao, Gang An
Journal: Blood
Blood (2023) 142 (Supplement 1): 4667.
https://doi.org/10.1182/blood-2023-179735
Published: 2023
Journal Articles

Efficacy and Safety of Selinexor-Based Combination Therapy in CNS Lymphoma: A Retrospective Experience

Li Li, Yan Ma, Xiaobo Wang, Zhiming Li, Zhiguang Lin, Qi Zhang, Jay Mei, Jingjing Ma, Xin Gao, Hui Kang, Zhijia Zhao, Hang Yang, Qing Li, Mengxue Zhang, Yingbo Zhou, Bobin Chen
Journal: Blood
Blood (2023) 142 (Supplement 1): 6301.
https://doi.org/10.1182/blood-2023-184682
Published: 2023
Journal Articles

Dietary iron restriction protects against vaso-occlusion and organ damage in murine sickle cell disease

Brief Report
Huihui Li, Jacob S. Kazmi, Sungkyun Lee, Dachuan Zhang, Xin Gao, Maria Maryanovich, Lidiane Torres, Divij Verma, Libusha Kelly, Yelena Z. Ginzburg, Paul S. Frenette, Deepa Manwani
Journal: Blood
Blood (2023) 141 (2): 194–199.
https://doi.org/10.1182/blood.2022016218
Published: 2023
Includes: Multimedia, Supplemental data
Journal Articles

Dietary Iron Restriction Alters Microbiota-Host Crosstalk and Protects Against Vaso-Occlusion and Organ Damage in Sickle Cell Disease Mice

Huihui Li, Jacob S Kazmi, Sungkyun Lee, Dachuan Zhang, Xin Gao, Maria Marianovich, Lidiane S. Torres, Divij Verma, Libusha Kelly, Yelena Ginzburg, Paul S. Frenette, Deepa Manwani
Journal: Blood
Blood (2022) 140 (Supplement 1): 439–440.
https://doi.org/10.1182/blood-2022-162772
Published: 2022
Journal Articles

Asxl1 loss cooperates with oncogenic Nras in mice to reprogram the immune microenvironment and drive leukemic transformation

Xiaona You, Fabao Liu, Moritz Binder, Alexis Vedder, Terra Lasho, Zhi Wen, Xin Gao, Evan Flietner, Adhithi Rajagopalan, Yun Zhou, Christy Finke, Abhishek Mangaonkar, Ruiqi Liao, Guangyao Kong, Erik A. Ranheim, Nathalie Droin, Anthony M. Hunter, Sergey Nikolaev, Maria Balasis, Omar Abdel-Wahab, Ross L. Levine, Britta Will, Kalyan Vara Ganesh Nadiminti, David Yang, Klaus Geissler, Eric Solary, Wei Xu, Eric Padron, Mrinal M. Patnaik, Jing Zhang
Journal: Blood
Blood (2022) 139 (7): 1066–1079.
https://doi.org/10.1182/blood.2021012519
Published: 2022
Includes: Supplemental data
Journal Articles

Regulation of CNS Lymphoma Progression By the Myeloid Microenvironment

Hua-Xin Gao, Eleanor Fraser, Mario Merlini, Huimin Geng, Lingjing Chen, Ming Lu, Yasmin Moshfegh, Joseph Cleveland, Jae Ryu, Jigyasa Sharma, David A. Solomon, Katerina Akassoglou, Clifford Lowell, James L. Rubenstein
Journal: Blood
Blood (2021) 138 (Supplement 1): 448.
https://doi.org/10.1182/blood-2021-153839
Published: 2021
Journal Articles

Macrophage Transfer to HSCs Assigns Residence in Bone Marrow

Xin GAO, PhD, Philip Boulais, PhD, Masato Tanaka, Christopher Richard Marlein, PhD, Paul S. Frenette, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 276.
https://doi.org/10.1182/blood-2019-123762
Published: 2019
Journal Articles

Development of a Pathway-Directed Drug Screen Platform for Cutaneous T Cell Lymphoma Using Patient-Derived Xenograft Models

CHI-HENG WU, PhD, Chen-Yen Yang, PhD, Linlin Wang, MD PhD, Hua-Xin Gao, PhD, Rakhshandehroo Taha, Shervin Afghani, Laura Pincus, MD, Ronald Balassanian, MD, James Rubenstein, Ryan Gill, MD PhD, Sourav Bandyopadhyay, PhD, Frank McCormick, PhD, Mark Moasser, MD, Weiyun Z. Ai, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1578.
https://doi.org/10.1182/blood-2019-122589
Published: 2019
Journal Articles

Response Rate, Event-Free Survival (EFS), and Overall Survival (OS) in Newly-Diagnosed Acute Myeloid Leukemia (AML): U.S. Food and Drug Administration (FDA) Trial-Level and Patient-Level Analyses

Kelly J. Norsworthy, MD, Xin Gao, PhD, Chia-Wen Ko, PhD, Jiaxi Zhou, MS, Yutao Gong, PhD, Yuan Li Shen, PhD, Rajeshwari Sridhara, PhD, Albert B. Deisseroth, MD PhD, Ann T. Farrell, MD, Richard Pazdur, MD, Gideon Blumenthal, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2670.
https://doi.org/10.1182/blood-2018-99-119678
Published: 2018
Journal Articles

Application of Hyperpolarized 13C Magnetic Resonance Imaging to Detect Target Inhibition of NFkB Activation in Preclinical Patient-Derived Models of CNS Lymphoma

Huimin Geng, PhD, Brice Tiret, PhD, Hua-Xin Gao, PhD, Cigall Kadoch, PhD, Ming Lu, PhD, Lingjing Chen, PhD, Ilwoo Park, PhD, Gerd Melkus, PhD, Adam Elkhaled, PhD, John Kurhanewicz, PhD, Lisa Drew, PhD, Sebastien Degorce, PhD, Michele Mayo, PhD, Keith Dillman, PhD, Rana Anjum, PhD, Andrew Bloecher, PhD, Myriam Chaumeil, PhD, James Rubenstein, MD, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2840.
https://doi.org/10.1182/blood-2018-99-117625
Published: 2018
Journal Articles

Second Line Systemic Treatments Including Extracorporeal Photopheresis Among Patients with Chronic Graft Versus Host Disease (cGVHD) in the United States, 2009-2016

Namita Joshi, PhD MS, BPharm, Linlin Luo, MSc, Xingyue Huang, PhD, Ghaith Mitri, MD, Belinda Lovelace, PharmD, An Pham, PharmD, MBA, FAHA, Xin Gao, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4490.
https://doi.org/10.1182/blood.V130.Suppl_1.4490.4490
Published: 2017
Journal Articles

Integrating Enhancer Mechanisms to Establish a Hierarchical Blood Development Program

Charu Mehta, MS, Kirby D Johnson, Xin Gao, Irene Ong, Koichi Ricardo Katsumura, MD PhD, Skye Courtney McIver, PhD, Erik A. Ranheim, MD PhD, Emery H Bresnick, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 7.
https://doi.org/10.1182/blood.V130.Suppl_1.7.7
Published: 2017
Journal Articles

Use of Extracorporeal Photopheresis (ECP) in the Treatment of Patients with Cutaneous T-Cell Lymphoma (CTCL), 2010-2015

You-Li Ling, PhD, Xingyue Huang, PhD, Ghaith Mitri, MD, An Pham, PharmD, MBA, FAHA, Belinda Lovelace, PharmD, Robert M. Knobler, MD, Xin Gao, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4093.
https://doi.org/10.1182/blood.V130.Suppl_1.4093.4093
Published: 2017
Journal Articles

p53 −/− synergizes with enhanced Nras G12D signaling to transform megakaryocyte-erythroid progenitors in acute myeloid leukemia

Jingfang Zhang, Guangyao Kong, Adhithi Rajagopalan, Li Lu, Jingming Song, Mohamed Hussaini, Xinmin Zhang, Erik A. Ranheim, Yangang Liu, Jinyong Wang, Xin Gao, Yuan-I Chang, Kirby D. Johnson, Yun Zhou, David Yang, Bhavana Bhatnagar, David M. Lucas, Emery H. Bresnick, Xuehua Zhong, Eric Padron, Jing Zhang
Journal: Blood
Blood (2017) 129 (3): 358–370.
https://doi.org/10.1182/blood-2016-06-719237
Published: 2017
Includes: Supplemental data
Journal Articles

A GATA-2-GPR65 Regulatory Module Controls Hematopoietic Stem Cell Generation

Xin Gao, Tongyu Wu, Jamie Lahvic, Kirby D. Johnson, Erik A. Ranheim, MD, Leonard I. Zon, MD, Emery H Bresnick, PhD
Journal: Blood
Blood (2015) 126 (23): 1176.
https://doi.org/10.1182/blood.V126.23.1176.1176
Published: 2015
Journal Articles

Genetic Basis For Hematopoietic Stem Cell Generation In The Mammalian Embryo

Xin Gao, Kirby D Johnson, PhD, Yuan-I Chang, PhD, Meghan E Boyer, Colin N Dewey, PhD, Jing Zhang, PhD, Emery Bresnick, PhD
Journal: Blood
Blood (2013) 122 (21): 3667.
https://doi.org/10.1182/blood.V122.21.3667.3667
Published: 2013
Journal Articles

Novel Intracranial Xenografts Of CNS Lymphoma Implicate a Role For Cereblon As a Mediator Of Lenalidomide Efficacy

Hua-Xin Gao, Ph.D., Shawn Anderson, Cigall Kadoch, Ph.D., Mekhala Maiti, Ph.D., Lingjing Chen, Ph.D., Dong-Han Yao, Gerd Melkus, Ph.D., Maria Wang, Ph.D., Yan Ren, Ph.D., Michael Breider, Ph.D., Carla Heise, PhD, Clifford A. Lowell, MD, PhD, Colin Collins, Ph.D., James L. Rubenstein, M.D., Ph.D.
Journal: Blood
Blood (2013) 122 (21): 374.
https://doi.org/10.1182/blood.V122.21.374.374
Published: 2013
Journal Articles

CXCL13 plus interleukin 10 is highly specific for the diagnosis of CNS lymphoma

James L. Rubenstein, Valerie S. Wong, Cigall Kadoch, Hua-Xin Gao, Ramon Barajas, Lingjing Chen, S. Andrew Josephson, Brian Scott, Vanja Douglas, Mekhala Maiti, Lawrence D. Kaplan, Patrick A. Treseler, Soonmee Cha, Jimmy H. Hwang, Paola Cinque, Jason G. Cyster, Clifford Lowell
Journal: Blood
Blood (2013) 121 (23): 4740–4748.
https://doi.org/10.1182/blood-2013-01-476333
Published: 2013
Includes: Supplemental data
Journal Articles

Genetic Determinants of the Definitive Hematopoietic Stem/Progenitor Cell Compartment

Kirby D Johnson, PhD, Xin Gao, Rajendran Sanalkumar, PhD, Amy P Hsu, BA, Myung-Jeom Ryu, PhD, Jinyong Wang, PhD, Meghan E Boyer, Yangang Liu, Katherine R Calvo, MD, PhD, Sunduz Keles, PhD, Jing Zhang, PhD, Steven M. Holland, MD, Emery H Bresnick, PhD
Journal: Blood
Blood (2012) 120 (21): 1226.
https://doi.org/10.1182/blood.V120.21.1226.1226
Published: 2012