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Jinyong Wang
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Journal Articles

p53 −/− synergizes with enhanced Nras G12D signaling to transform megakaryocyte-erythroid progenitors in acute myeloid leukemia

Jingfang Zhang, Guangyao Kong, Adhithi Rajagopalan, Li Lu, Jingming Song, Mohamed Hussaini, Xinmin Zhang, Erik A. Ranheim, Yangang Liu, Jinyong Wang, Xin Gao, Yuan-I Chang, Kirby D. Johnson, Yun Zhou, David Yang, Bhavana Bhatnagar, David M. Lucas, Emery H. Bresnick, Xuehua Zhong, Eric Padron, Jing Zhang
Journal: Blood
Blood (2017) 129 (3): 358–370.
https://doi.org/10.1182/blood-2016-06-719237
Published: 2017
Includes: Supplemental data
Journal Articles

Loss Of p53 Promotes Transformation Of Oncogenic Nras-Induced Chronic Myelomonocytic Leukemia To An Acute Phase

Jingfang Zhang, Yangang Liu, Guangyao Kong, PhD, Yuan-I Chang, PhD, Erik A. Ranheim, MD, Jinyong Wang, PhD, Juan Du, PhD, Alisa Damnernsawad, Jing Zhang, PhD
Journal: Blood
Blood (2013) 122 (21): 3790.
https://doi.org/10.1182/blood.V122.21.3790.3790
Published: 2013
Journal Articles

Non-Irradiation Approach To Study Hematopoiesis and Leukemogenesis In a De Novo Murine Model Of Hematopoietic/Leukemia Stem Cell Transplant

Xiaofei Liu, Dan Yang, Shumin Fang, Yang Geng, Qianhao Zhao, Pengjie Yang, Siying Peng, Yuelei Shen, Guangjin Pan, Jinyong Wang
Journal: Blood
Blood (2013) 122 (21): 4836.
https://doi.org/10.1182/blood.V122.21.4836.4836
Published: 2013
Journal Articles

Nras G12D/+ promotes leukemogenesis by aberrantly regulating hematopoietic stem cell functions

Brief Report
Jinyong Wang, Guangyao Kong, Yangang Liu, Juan Du, Yuan-I Chang, Sin Ruow Tey, Xinmin Zhang, Erik A. Ranheim, Marc K. Saba-El-Leil, Sylvain Meloche, Alisa Damnernsawad, Jingfang Zhang, Jing Zhang
Journal: Blood
Blood (2013) 121 (26): 5203–5207.
https://doi.org/10.1182/blood-2012-12-475863
Published: 2013
Includes: Supplemental data
Journal Articles

Genetic Determinants of the Definitive Hematopoietic Stem/Progenitor Cell Compartment

Kirby D Johnson, PhD, Xin Gao, Rajendran Sanalkumar, PhD, Amy P Hsu, BA, Myung-Jeom Ryu, PhD, Jinyong Wang, PhD, Meghan E Boyer, Yangang Liu, Katherine R Calvo, MD, PhD, Sunduz Keles, PhD, Jing Zhang, PhD, Steven M. Holland, MD, Emery H Bresnick, PhD
Journal: Blood
Blood (2012) 120 (21): 1226.
https://doi.org/10.1182/blood.V120.21.1226.1226
Published: 2012
Journal Articles

Endogenous Nras G12D/+ and G12D/G12D Distinctly Regulate Self-Renewal and Differentiation of Haematopoietic Stem Cells

Guangyao Kong, Jinyong Wang, PhD, Yangang Liu, Juan Du, Alisa Damnernsawad, Erik A. Ranheim, MD, Myung-Jeom Ryu, PhD, Jing Zhang, PhD
Journal: Blood
Blood (2012) 120 (21): 4086.
https://doi.org/10.1182/blood.V120.21.4086.4086
Published: 2012
Journal Articles

Endogenous Oncogenic Nras Signaling Promotes Proliferative Exhaustion of Hematopoietic Stem Cells Through a Dose-Dependent Hyperactivation of ERK,

Jinyong Wang, PhD, Yangang Liu, Juan Du, Myung-Jeom Ryu, Erik A. Ranheim, MD, PhD, Jing Zhang
Journal: Blood
Blood (2011) 118 (21): 3997.
https://doi.org/10.1182/blood.V118.21.3997.3997
Published: 2011
Journal Articles

Role of CD44 in Endogenous Kras G12D -mediated Myeloproliferative Neoplasm

Juan Du, Yangang Liu, Lixuan Tan, Juinn Cherng Lo, Jinyong Wang, PhD, Myung-Joem Ryu, Jingfang Zhang, Jing Zhang
Journal: Blood
Blood (2011) 118 (21): 1398.
https://doi.org/10.1182/blood.V118.21.1398.1398
Published: 2011
Journal Articles

Endogenous oncogenic Nras mutation initiates hematopoietic malignancies in a dose- and cell type-dependent manner

Jinyong Wang, Yangang Liu, Zeyang Li, Zhongde Wang, Li Xuan Tan, Myung-Jeom Ryu, Benjamin Meline, Juan Du, Ken H. Young, Erik Ranheim, Qiang Chang, Jing Zhang
Journal: Blood
Blood (2011) 118 (2): 368–379.
https://doi.org/10.1182/blood-2010-12-326058
Published: 2011
Includes: Supplemental data
Journal Articles

Endogenous oncogenic Nras mutation promotes aberrant GM-CSF signaling in granulocytic/monocytic precursors in a murine model of chronic myelomonocytic leukemia

Jinyong Wang, Yangang Liu, Zeyang Li, Juan Du, Myung-Jeom Ryu, Philip R. Taylor, Mark D. Fleming, Ken H. Young, Henry Pitot, Jing Zhang
Journal: Blood
Blood (2010) 116 (26): 5991–6002.
https://doi.org/10.1182/blood-2010-04-281527
Published: 2010
Includes: Supplemental data
Journal Articles

Endogenous Oncogenic Nras Mutation Leads to Aberrant GM-CSF Signaling In Granulocytic/Monocytic Precursors In a Murine Model of Chronic Myelomonocytic Leukemia

Jinyong Wang, PhD, Yangang Liu, PhD, Zeyang Li, PhD, Juan Du, PhD, Myung-Jeom Ryu, PhD, Philip Taylor, Mark D. Fleming, MD, DPhil, Ken H Young, PhD, Henry Pitot, PhD, Jing Zhang, PhD
Journal: Blood
Blood (2010) 116 (21): 4180.
https://doi.org/10.1182/blood.V116.21.4180.4180
Published: 2010
Journal Articles

Endogenous Oncogenic Nras Mutation Initiates T-Cell Leukemia/Lymphoma In a Dose-Dependent Manner

Jinyong Wang, PhD, Zeyang Li, PhD, Zhongde Wang, PhD, Yangang Liu, PhD, Myung-Jeom Ryu, PhD, Benjamin Meline, PhD, Juan Du, PhD, Ken H Young, PhD, Qiang Chang, Jing Zhang, PhD
Journal: Blood
Blood (2010) 116 (21): 4183.
https://doi.org/10.1182/blood.V116.21.4183.4183
Published: 2010