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Journal Articles

TMPRSS6 Antisense Oligonucleotide Therapy Reverses Inflammation in Jak2 V617F Mutant Mice

Maayan Levy, Huihui Li, Andrew Dunbar, Zixing Huang, Young Park, Min Lu, Pinanong Na Phattalung, Marina Planoutene, Carla Casu, Stefano Rivella, Shuling Guo, Ross L Levine, Ronald Hoffman, Yelena Ginzburg

Blood (2024) 144 (Supplement 1): 8.

https://doi.org/10.1182/blood-2024-203806

Published: 2024

Journal Articles

Dietary iron restriction protects against vaso-occlusion and organ damage in murine sickle cell disease

Huihui Li, Jacob S. Kazmi, Sungkyun Lee, Dachuan Zhang, Xin Gao, Maria Maryanovich, Lidiane Torres, Divij Verma, Libusha Kelly, Yelena Z. Ginzburg, Paul S. Frenette, Deepa Manwani

Blood (2023) 141 (2): 194–199.

https://doi.org/10.1182/blood.2022016218

Published: 2023

Includes: Multimedia, Supplemental data

Journal Articles

Dietary Iron Restriction Alters Microbiota-Host Crosstalk and Protects Against Vaso-Occlusion and Organ Damage in Sickle Cell Disease Mice

Huihui Li, Jacob S Kazmi, Sungkyun Lee, Dachuan Zhang, Xin Gao, Maria Marianovich, Lidiane S. Torres, Divij Verma, Libusha Kelly, Yelena Ginzburg, Paul S. Frenette, Deepa Manwani

Blood (2022) 140 (Supplement 1): 439–440.

https://doi.org/10.1182/blood-2022-162772

Published: 2022

Journal Articles

Microbial Metabolites Target Histone Deacetylases to Trigger Vascular Inflammation in Sickle Cell Disease

Lidiane S. Torres, Simone Sidoli, Huihui Li, Sofia De Oliveira, Paul S. Frenette, Andres Hidalgo, Keisuke Ito

Blood (2022) 140 (Supplement 1): 435–436.

https://doi.org/10.1182/blood-2022-169203

Published: 2022

Journal Articles

Ferritin is secreted via 2 distinct nonclassical vesicular pathways

Blood (2018) 131 (3): 342–352.

https://doi.org/10.1182/blood-2017-02-768580

Published: 2018

Includes: Supplemental data

Journal Articles

Decreasing TfR1 expression reverses anemia and hepcidin suppression in β-thalassemic mice

Huihui Li, Tenzin Choesang, Weili Bao, Huiyong Chen, Maria Feola, Daniel Garcia-Santos, Jie Li, Shuming Sun, Antonia Follenzi, Petra Pham, Jing Liu, Jinghua Zhang, Prem Ponka, Xiuli An, Narla Mohandas, Robert E. Fleming, Stefano Rivella, Guiyuan Li, Yelena Z. Ginzburg

Blood (2017) 129 (11): 1514–1526.

https://doi.org/10.1182/blood-2016-09-742387

Published: 2017

Includes: Supplemental data

Journal Articles

Role of Activated Pleckstrin-2 and Down-Stream Effects on Ineffective Erythropoiesis in β-Thalassemic Mice

Maria Feola, BSc, MSc, Andrea Zamperone, PhD, Weili Bao, MS, Tenzin Choesang, MS, Huihui Li, MS, Guiyuan Li, MD, Shilpa M. Hattangadi, MD, Christopher E. Mason, PhD, Peng Ji, MD PhD, Antonia Follenzi, MD PhD, Yelena Ginzburg

Blood (2016) 128 (22): 1011.

https://doi.org/10.1182/blood.V128.22.1011.1011

Published: 2016

Journal Articles

Down-Regulation of TfR1 Increases Erythroid Precursor Enucleation and Hepatocyte Hepcidin Expression in ß-Thalassemic Mice

Huihui Li, MS, Tenzin Choesang, MS, Weili Bao, MS, Lionel Blanc, PhD, Huiyong Chen, PhD, Maria Feola, MS, Jie Li, MD, Guiyuan Li, MD, Shuming Sun, PhD, Antonia Follenzi, MDPhD, Petra Pham, MS, Xiuli An, MD PhD, Narla Mohandas, DSc, Robert E Fleming, MD, Stefano Rivella, PhD, Yelena Ginzburg, MD

Blood (2015) 126 (23): 754.

https://doi.org/10.1182/blood.V126.23.754.754

Published: 2015

Journal Articles

Role of Pleckstrin 2 in Improved Erythropoiesis of Transferrin-Treated Beta-Thalassemic Mice

Maria Feola, MS, Andrea Zamperone, Weili Bao, MS, Tenzin Choesang, MS, Huihui Li, MS, Guiyuan Li, MD, Antonia Follenzi, MD PhD, Shilpa M Hattangadi, MD, Christopher Mason, PhD, Peng Ji, MD PhD, Yelena Ginzburg, MD

Blood (2015) 126 (23): 755.

https://doi.org/10.1182/blood.V126.23.755.755

Published: 2015

Journal Articles

Increased Hepcidin Expression in β-Thalassemic Mice Treated with Apo-Transferrin Is Associated with Increased Smad1/5/8 and Decreased Erk1/2 Pathway Activation

Huiyong Chen, PhD, Tenzin Choesang, Petra Pham, Weili Bao, Maria Feola, Huihui Li, MS, Mark Westerman, PhD, Guiyuan Li, Antonia Follenzi, Lionel Blanc, PhD, Stefano Rivella, PhD, Robert E Fleming, MD, Yelena Ginzburg, MD

Blood (2014) 124 (21): 747.

https://doi.org/10.1182/blood.V124.21.747.747

Published: 2014

Journal Articles

Exogenous Apo-Transferrin Increases Monoferric Transferrin, Decreasing Cytosolic Iron Uptake and Heme and Globin Synthesis in β-Thalassemic Mice

Tenzin Choesang, Huihui Li, MS, Michael Dussiot, Thiago Maciel, PhD, Laura Breda, PhD, Daniel Garcia Santos, PhD, Huiyong Chen, PhD, Maria Feola, Weili Bao, Petra Pham, Antonia Follenzi, Guiyuan Li, Ivan Cruz Moura, PhD, Prem Ponka, MD PhD, Robert E Fleming, MD, Stefano Rivella, PhD, Yelena Ginzburg, MD

Blood (2014) 124 (21): 4037.

https://doi.org/10.1182/blood.V124.21.4037.4037

Published: 2014

Journal Articles

Changes in TfR1 Expression and Trafficking Correlate with Erythroid Effectiveness in β-Thalassemic Mice

Huihui Li, MS, Lionel Blanc, PhD, Tenzin Choesang, Huiyong Chen, PhD, Maria Feola, Weili Bao, Petra Pham, Antonia Follenzi, Guiyuan Li, Yelena Ginzburg, MD

Blood (2014) 124 (21): 51.

https://doi.org/10.1182/blood.V124.21.51.51

Published: 2014

Journal Articles

Role Of Transferrin In Recovery From Phlebotomy In Iron Replete Or Iron Deficient Mice

Huihui Li, MS, Jayesh Shah, Charles B. Hall, PhD, Yelena Ginzburg, MD

Blood (2013) 122 (21): 961.

https://doi.org/10.1182/blood.V122.21.961.961

Published: 2013

Journal Articles

Inhibition Of Erythropoiesis By Iron Overload Is Mediated Through TGFβ Signaling

Krishna Gundabolu, MD, Huiyong Chen, Huihui Li, MS, Lohith Shakaladevanapura, Tushar D. Bhagat, Nishant Vallumsetla, Yelena Ginzburg, MD, Amit Verma

Blood (2013) 122 (21): 2787.

https://doi.org/10.1182/blood.V122.21.2787.2787

Published: 2013

Journal Articles

Evidence Of Relative Iron Deficiency in Apheresis Platelet Donors Correlates With Donation Frequency

Frances Condon, Huihui Li, MS, Debra Kessler, RN, Vijay Nandi, Tomas Ganz, MD, PhD, Elizabeta Nemeth, PhD, Mark Westerman, PhD, Beth H Shaz, MD, Yelena Ginzburg, MD

Blood (2013) 122 (21): 1155.

https://doi.org/10.1182/blood.V122.21.1155.1155

Published: 2013

Journal Articles

Quantitative analysis of murine terminal erythroid differentiation in vivo: novel method to study normal and disordered erythropoiesis

Jing Liu, Jianhua Zhang, Yelena Ginzburg, Huihui Li, Fumin Xue, Lucia De Franceschi, Joel Anne Chasis, Narla Mohandas, Xiuli An

Blood (2013) 121 (8): e43–e49.

https://doi.org/10.1182/blood-2012-09-456079

Published: 2013

Journal Articles

Decreased hepcidin expression in murine β-thalassemia is associated with suppression of Bmp/Smad signaling

Nermi L. Parrow, Sara Gardenghi, Pedro Ramos, Carla Casu, Robert W. Grady, Erik R. Anderson, Yatrik M. Shah, Huihui Li, Yelena Z. Ginzburg, Robert E. Fleming, Stefano Rivella

Blood (2012) 119 (13): 3187–3189.

https://doi.org/10.1182/blood-2012-01-405563

Published: 2012

Journal Articles

Hepcidin in Male Double Red Blood Cell Donors - Relationship Between Parameters of Iron Metabolism and Erythropoiesis

Shuo Wang, Huihui Li, MS, Lisa Sarran, Gordana Olbina, PhD, Mark Westerman, PhD, Elizabeta Nemeth, PhD, Eric E. Bouhassira, PhD, Tomas Ganz, MD, PhD, Yelena Ginzburg, MD

Blood (2011) 118 (21): 2109.

https://doi.org/10.1182/blood.V118.21.2109.2109

Published: 2011

Journal Articles

Exogenous Apo-Transferrin Reduces Extramedullary and Increases Effectiveness of Erythropoiesis in a Mouse Model of Beta-Thalassemia Major

Huihui Li, MS, Sara Gardenghi, PhD, Leni vonBonsdorff, PhD, Stefano Rivella, PhD, Yelena Ginzburg, MD

Blood (2011) 118 (21): 1095.

https://doi.org/10.1182/blood.V118.21.1095.1095

Published: 2011

Journal Articles

Increased Transferrin Concentration Ameliorates Anemia in Beta-Thalassemic Mice Through Changes in Iron Uptake and TfR1 Trafficking

Huihui Li, MS, Lionel Blanc, PhD, Tenzin Choesang, Maya Shvartsman, Leni vonBonsdorff, PhD, Zvi Ioav Cabantchik, MD, PhD, Yelena Ginzburg, MD

Blood (2011) 118 (21): 906.

https://doi.org/10.1182/blood.V118.21.906.906

Published: 2011

NARROW

TMPRSS6 Antisense Oligonucleotide Therapy Reverses Inflammation in Jak2 V617F Mutant Mice

Dietary iron restriction protects against vaso-occlusion and organ damage in murine sickle cell disease

Dietary Iron Restriction Alters Microbiota-Host Crosstalk and Protects Against Vaso-Occlusion and Organ Damage in Sickle Cell Disease Mice

Microbial Metabolites Target Histone Deacetylases to Trigger Vascular Inflammation in Sickle Cell Disease

Ferritin is secreted via 2 distinct nonclassical vesicular pathways

Decreasing TfR1 expression reverses anemia and hepcidin suppression in β-thalassemic mice

Role of Activated Pleckstrin-2 and Down-Stream Effects on Ineffective Erythropoiesis in β-Thalassemic Mice

Down-Regulation of TfR1 Increases Erythroid Precursor Enucleation and Hepatocyte Hepcidin Expression in ß-Thalassemic Mice

Role of Pleckstrin 2 in Improved Erythropoiesis of Transferrin-Treated Beta-Thalassemic Mice

Increased Hepcidin Expression in β-Thalassemic Mice Treated with Apo-Transferrin Is Associated with Increased Smad1/5/8 and Decreased Erk1/2 Pathway Activation

Exogenous Apo-Transferrin Increases Monoferric Transferrin, Decreasing Cytosolic Iron Uptake and Heme and Globin Synthesis in β-Thalassemic Mice

Changes in TfR1 Expression and Trafficking Correlate with Erythroid Effectiveness in β-Thalassemic Mice

Role Of Transferrin In Recovery From Phlebotomy In Iron Replete Or Iron Deficient Mice

Inhibition Of Erythropoiesis By Iron Overload Is Mediated Through TGFβ Signaling

Evidence Of Relative Iron Deficiency in Apheresis Platelet Donors Correlates With Donation Frequency

Quantitative analysis of murine terminal erythroid differentiation in vivo: novel method to study normal and disordered erythropoiesis

Decreased hepcidin expression in murine β-thalassemia is associated with suppression of Bmp/Smad signaling

Hepcidin in Male Double Red Blood Cell Donors - Relationship Between Parameters of Iron Metabolism and Erythropoiesis

Exogenous Apo-Transferrin Reduces Extramedullary and Increases Effectiveness of Erythropoiesis in a Mouse Model of Beta-Thalassemia Major

Increased Transferrin Concentration Ameliorates Anemia in Beta-Thalassemic Mice Through Changes in Iron Uptake and TfR1 Trafficking

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American Society of Hematology

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American Society of Hematology

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