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Journal Articles

An erythroid-specific lentiviral vector improves anemia and iron metabolism in a new model of XLSA.

Carlo Castruccio Castracani, Laura Breda, Tyler Ellis Papp, Amaliris Guerra, Enrico Radaelli, Charles-Antoine Assenmacher, Giovanni Finesso, Barbara L Mui, Ying K. Tam, Simona Fontana, Chiara Riganti, Veronica Fiorito, Sara Petrillo, Emanuela Tolosano, Hamideh Parhiz, Stefano Rivella

Blood blood.2024025846.

https://doi.org/10.1182/blood.2024025846

Published: 2024

Includes: Supplemental data

Journal Articles

TNFα Plays Essential Role in Resolution of Anemia of Inflammation in Tnfαko Mice Treated with Heat-Killed Brucella Abortus

Vania Lo Presti, Ding-wen Chen, Ana Martins, Pankaj Sharma, Yelena Ginzburg, Carlo Castruccio Castracani, Carla Casu, Ritama Gupta, Raffaella Gozzelino, Edward Behrens, Laura F Bennett, Robert Paulson, Peter Kurre, Stefano Rivella, Amaliris Guerra

Blood (2024) 144 (Supplement 1): 168.

https://doi.org/10.1182/blood-2024-212272

Published: 2024

Journal Articles

TMPRSS6 Antisense Oligonucleotide Therapy Reverses Inflammation in Jak2 V617F Mutant Mice

Maayan Levy, Huihui Li, Andrew Dunbar, Zixing Huang, Young Park, Min Lu, Pinanong Na Phattalung, Marina Planoutene, Carla Casu, Stefano Rivella, Shuling Guo, Ross L Levine, Ronald Hoffman, Yelena Ginzburg

Blood (2024) 144 (Supplement 1): 8.

https://doi.org/10.1182/blood-2024-203806

Published: 2024

Journal Articles

TFR2 Coordinates Erythroid Iron Availability and Erythropoietin Receptor Sensitivity By Monoferric Transferrin Forms

Amaliris Guerra, Pankaj Sharma, Xiuli An, Nermi L. Parrow, Robert E. Fleming, Yelena Ginzburg, Stefano Rivella

Blood (2024) 144 (Supplement 1): 2468.

https://doi.org/10.1182/blood-2024-211984

Published: 2024

Journal Articles

In Utero mRNA Lipid Nanoparticle Delivery in a Murine Model of Fanconi Anemia

Linah Omer, William Johnston, Sarah Adams, Omar Banda, Elena Sofia Vivona, Stefano Rivella, Mohamad-Gabriel Alameh, William Peranteau, Peter Kurre

Blood (2024) 144 (Supplement 1): 2202.

https://doi.org/10.1182/blood-2024-211241

Published: 2024

Journal Articles

An Erythroid-Specific Lentiviral Vector Improves Anemia and Iron Metabolism in a New Model of Xlsa

Carlo Castruccio Castracani, Laura Breda, Tyler E. Papp, Amaliris Guerra, Enrico Radaelli, Charles-Antoine Assenmacher, Giovanni Finesso, Barbara Mui, Ying K. Tam, Simona Fontana, Chiara Riganti, Veronica Fiorito, Sara Petrillo, Emanuela Tolosano, Hamideh Parhiz, Stefano Rivella

Blood (2024) 144 (Supplement 1): 2195.

https://doi.org/10.1182/blood-2024-200747

Published: 2024

Journal Articles

Use of HSC-targeted LNP to generate a mouse model of lethal α-thalassemia and treatment via lentiviral gene therapy

Blood (2024) 144 (15): 1633–1645.

https://doi.org/10.1182/blood.2023023349

Published: 2024

Includes: Supplemental data

Journal Articles

Phenotypic HSPC Rescue By RNA Lipid Nanoparticles in a Murine Model of Fanconi Anemia

Linah Omer, Omar Banda, Sarah Adams, Seul K Jung, Stefano Rivella, Mohamad-Gabriel Alameh, Drew Weissman, Peter Kurre

Blood (2023) 142 (Supplement 1): 3625.

https://doi.org/10.1182/blood-2023-188193

Published: 2023

Journal Articles

Differential Effect of Transferrin Lobe Iron Occupancy on a Murine Model of Inflammation

Nermi L. Parrow, Nisha Ajit George, Faris Ali, Nadia Wattad, Amaliris Guerra, Yelena Ginzburg, Stefano Rivella, Robert E. Fleming

Blood (2023) 142 (Supplement 1): 1095.

https://doi.org/10.1182/blood-2023-190984

Published: 2023

Journal Articles

Differential Effects of Monoferric Transferrin Forms on Erythropoiesis Are Mediated By TFR2

Amaliris Guerra, Ariel Rivera, Nolan Hamilton, Xiuli An, Nermi L. Parrow, Yelena Ginzburg, Robert E. Fleming, Stefano Rivella

Blood (2023) 142 (Supplement 1): 3846.

https://doi.org/10.1182/blood-2023-189107

Published: 2023

Journal Articles

In Vivo Modification of Hematopoietic Stem Cells By Targeted Lipid Nanoparticles Encapsulating mRNA

Laura Breda, Tyler E Papp, Michael Triebwasser, Amir Yadegari, Megan T Fedorky, Naoto Tanaka, Houping Ni, Drew Weissman, Stefano Rivella, Hamideh Parhiz

Blood (2022) 140 (Supplement 1): 305–306.

https://doi.org/10.1182/blood-2022-165089

Published: 2022

Journal Articles

Direct Delivery of mRNA-Loaded Lipid Nanoparticles to the Hematopoietic Stem Cell Niche

Omar Banda, Mohamad-Gabriel Alameh, Seul Jung, Drew Weissman, Stefano Rivella, Peter Kurre

Blood (2022) 140 (Supplement 1): 4923–4924.

https://doi.org/10.1182/blood-2022-159085

Published: 2022

Journal Articles

Combination of a TGF-β Ligand Trap (RAP-GRL) and TMPRSS6 -ASO Is Superior for Correcting β-Thalassemia

Amaliris Guerra, Perry Demsko, Ariel Rivera, Carlo Castruccio Castracani, Laura Breda, Naoto Tanaka, Shuling Guo, Stefano Rivella

Blood (2022) 140 (Supplement 1): 1944–1945.

https://doi.org/10.1182/blood-2022-166801

Published: 2022

Journal Articles

TNFα and Anti-IFNγ Rescues Chronic Anemia of Inflammation Phenotype in Tnfαko Mice Treated with Heat-Killed Brucella Abortus

Amaliris Guerra, Vania Lo Presti, Ding-Wen Chen, Ana Catarina Martins, Carlo Castruccio Castracani, Ritama Gupta, Laura Bennett, Raffaella Gozzelino, Robert Paulson, Peter Kurre, Stefano Rivella, Carla Casu

Blood (2022) 140 (Supplement 1): 5302–5303.

https://doi.org/10.1182/blood-2022-166643

Published: 2022

Journal Articles

Establishment of High Titer Baboon Endogenous Retrovirus Envelope Pseudotyped Lentiviral Vector Production Protocol Focusing on Syncytium Formation and Exfoliation

Kazuhiro Noguchi, Yasuhiro Ikawa, Mika Takenaka, Yuta Sakai, Toshihiro Fujiki, Rie Kuroda, Maxwell Chappell, Valentina Ghiaccio, Stefano Rivella, Taizo Wada

Blood (2022) 140 (Supplement 1): 12987–12989.

https://doi.org/10.1182/blood-2022-163144

Published: 2022

Journal Articles

The Effect of Monoferric Transferrins on Hypoferremia in a Murine Model of Inflammation

Nermi Parrow, Nisha George, Faris Ali, Nadia Wattad, Amaliris Guerra, Yelena Ginzburg, Stefano Rivella, Robert E Fleming

Blood (2022) 140 (Supplement 1): 2463–2464.

https://doi.org/10.1182/blood-2022-171130

Published: 2022

Journal Articles

Lnp-Targeting Hematopoietic Stem Cells and Lentiviral Gene Transfer to Generate and Rescue a Novel Mouse Model of Lethal Alpha-Thalassemia

Maxwell Chappell, Laura Breda, Danuta Jadwiga Jarocha, Michael Triebwasser, Tyler E Papp, Valentina Ghiaccio, Megan T Fedorky, Amaliris Guerra, Kandace Gollomp, Osheiza Y. Abdulmalik, Nattiya Teawtrakul, Stavros Glentis, Antonis Kattamis, Hamideh Parhiz, Stefano Rivella

Blood (2022) 140 (Supplement 1): 300–302.

https://doi.org/10.1182/blood-2022-166621

Published: 2022

Journal Articles

Differential Effects of Monoferric Forms of Transferrin on Mouse Models of Anemia of Inflammation and Congenital Anemia

Amaliris Guerra, Ana Catarina Martins, Ariel Rivera, Nermi Parrow, Raffaella Gozzelino, Yelena Ginzburg, Robert E Fleming, Stefano Rivella

Blood (2022) 140 (Supplement 1): 8179–8180.

https://doi.org/10.1182/blood-2022-166391

Published: 2022

Journal Articles

TNFα Controls the Delicate Balance between Erythropoiesis and Stem Cell Exhaustion during Inflammatory Stress

Amaliris Guerra, Vania Lo Presti, Ana Catarina Martins, Carlo Castruccio Castracani, Ritama Gupta, Rea Oikonomidou, Emir O'Hara, Carla Casu, Laura Bennett, Robert Paulson, Peter Kurre, Stefano Rivella, Raffaella Gozzelino

Blood (2021) 138 (Supplement 1): 2184.

https://doi.org/10.1182/blood-2021-152473

Published: 2021

Journal Articles

A Severe Mouse Model of Alpha-Thalassemia to Study Abnormal Iron Metabolism and Erythropoiesis, Hematopoietic Stem Cell Behavior and Development of a Gene Therapy Approach for Its Treatment

Maxwell Chappell, Danuta Jadwiga Jarocha, Laura Breda, Valentina Ghiaccio, Michael Triebwasser, Megan Fedorky, Amaliris Guerra, Kandace Gollomp, Nattiya Teawtrakul, Stavros Glentis, Antonis Kattamis, Osheiza Abdulmalik, Stefano Rivella

Blood (2021) 138 (Supplement 1): 2012.

https://doi.org/10.1182/blood-2021-151217

Published: 2021

NARROW

An erythroid-specific lentiviral vector improves anemia and iron metabolism in a new model of XLSA.

TNFα Plays Essential Role in Resolution of Anemia of Inflammation in Tnfαko Mice Treated with Heat-Killed Brucella Abortus

TMPRSS6 Antisense Oligonucleotide Therapy Reverses Inflammation in Jak2 V617F Mutant Mice

TFR2 Coordinates Erythroid Iron Availability and Erythropoietin Receptor Sensitivity By Monoferric Transferrin Forms

In Utero mRNA Lipid Nanoparticle Delivery in a Murine Model of Fanconi Anemia

An Erythroid-Specific Lentiviral Vector Improves Anemia and Iron Metabolism in a New Model of Xlsa

Use of HSC-targeted LNP to generate a mouse model of lethal α-thalassemia and treatment via lentiviral gene therapy

Phenotypic HSPC Rescue By RNA Lipid Nanoparticles in a Murine Model of Fanconi Anemia

Differential Effect of Transferrin Lobe Iron Occupancy on a Murine Model of Inflammation

Differential Effects of Monoferric Transferrin Forms on Erythropoiesis Are Mediated By TFR2

In Vivo Modification of Hematopoietic Stem Cells By Targeted Lipid Nanoparticles Encapsulating mRNA

Direct Delivery of mRNA-Loaded Lipid Nanoparticles to the Hematopoietic Stem Cell Niche

Combination of a TGF-β Ligand Trap (RAP-GRL) and TMPRSS6 -ASO Is Superior for Correcting β-Thalassemia

TNFα and Anti-IFNγ Rescues Chronic Anemia of Inflammation Phenotype in Tnfαko Mice Treated with Heat-Killed Brucella Abortus

Establishment of High Titer Baboon Endogenous Retrovirus Envelope Pseudotyped Lentiviral Vector Production Protocol Focusing on Syncytium Formation and Exfoliation

The Effect of Monoferric Transferrins on Hypoferremia in a Murine Model of Inflammation

Lnp-Targeting Hematopoietic Stem Cells and Lentiviral Gene Transfer to Generate and Rescue a Novel Mouse Model of Lethal Alpha-Thalassemia

Differential Effects of Monoferric Forms of Transferrin on Mouse Models of Anemia of Inflammation and Congenital Anemia

TNFα Controls the Delicate Balance between Erythropoiesis and Stem Cell Exhaustion during Inflammatory Stress

A Severe Mouse Model of Alpha-Thalassemia to Study Abnormal Iron Metabolism and Erythropoiesis, Hematopoietic Stem Cell Behavior and Development of a Gene Therapy Approach for Its Treatment

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American Society of Hematology

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ASH Publications

American Society of Hematology

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