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Journal Articles

TMPRSS6 Antisense Oligonucleotide Therapy Reverses Inflammation in Jak2 V617F Mutant Mice

Maayan Levy, Huihui Li, Andrew Dunbar, Zixing Huang, Young Park, Min Lu, Pinanong Na Phattalung, Marina Planoutene, Carla Casu, Stefano Rivella, Shuling Guo, Ross L Levine, Ronald Hoffman, Yelena Ginzburg

Blood (2024) 144 (Supplement 1): 8.

https://doi.org/10.1182/blood-2024-203806

Published: 2024

Journal Articles

CXCL8/CXCR2 signaling mediates bone marrow fibrosis and is a therapeutic target in myelofibrosis

Blood (2023) 141 (20): 2508–2519.

https://doi.org/10.1182/blood.2022015418

Published: 2023

Includes: Supplemental data

Journal Articles

Jak2 V617F Reversible Activation Shows an Essential Requirement for Jak2 V617F in Myeloproliferative Neoplasms (MPNs)

Blood (2022) 140 (Supplement 1): 803–804.

https://doi.org/10.1182/blood-2022-164827

Published: 2022

Journal Articles

The Second Generation Type II JAK2 Inhibitor, AJ1-10502, Demonstrates Enhanced Selectivity, Improved Therapeutic Efficacy and Reduced Mutant Cell Fraction Compared to Type I JAK2 Inhibitors in Models of Myeloproliferative Neoplasms (MPNs)

Shivam Rai, Jan Stetka, MARC Usart, Hui Hao-Shen, Young Park, Remie Houston, Anthony R. Martinez Benitez, Matthew Wereski, Emily Guzzardi, Sonali Persaud, Hailey Ramzan, Alan Futran, Charley Xu, Jeremy Greenwood, Sayan Mondal, Craig Masse, Ross L. Levine, Radek C. Skoda, Andrew Dunbar

Blood (2022) 140 (Supplement 1): 6722–6723.

https://doi.org/10.1182/blood-2022-162621

Published: 2022

Journal Articles

Aryl hydrocarbon receptor–targeted therapy for CD4 + T cell–mediated idiopathic pneumonia syndrome in mice

Soung-Min Lee, Chae Eun Kim, Ha Young Park, Eun Hye Yoon, Hae Jeong Won, Joo Mi Ahn, Nu Zen Na Nguyen, Minji Kim, Won Hee Jang, Won-Sik Lee, Mi Seon Kang, Myeonggyo Jeong, Hwayoung Yun, Suhyun Park, Sangwook Wu, Dong Hyun Kim, Byungsuk Kwon, Su-Kil Seo

Blood (2022) 139 (22): 3325–3339.

https://doi.org/10.1182/blood.2021013849

Published: 2022

Includes: Supplemental data

Journal Articles

Genomic profiling identifies somatic mutations predicting thromboembolic risk in patients with solid tumors

Blood (2021) 137 (15): 2103–2113.

https://doi.org/10.1182/blood.2020007488

Published: 2021

Includes: Supplemental data

Journal Articles

Increased Interleukin-8 (IL8)-CXCR2 Signaling Promotes Progression of Bone Marrow Fibrosis in Myeloproliferative Neoplasms

Andrew Dunbar, MD, Min Lu, PhDMD, Mirko Farina, MD, Young Park, BS, Julie Yang, PhD, Dongjoo Kim, PhD, Abdul Karzai, BS, Mohamed E Salama, MD, Jenna Snyder, BS, Aishwarya Krishnan, BS, Richard P. Koche, PhD, Rong Fan, PhD, Ross L. Levine, MD, Ronald Hoffman, MD

Blood (2020) 136 (Supplement 1): 6–7.

https://doi.org/10.1182/blood-2020-138843

Published: 2020

Journal Articles

Pathologic angiogenesis in the bone marrow of humanized sickle cell mice is reversed by blood transfusion

Shin-Young Park, Alessandro Matte, Yookyung Jung, Jina Ryu, Wilson Babu Anand, Eun-Young Han, Min Liu, Carmine Carbone, Davide Melisi, Takashi Nagasawa, Joseph J. Locascio, Charles P. Lin, Leslie E. Silberstein, Lucia De Franceschi

Blood (2020) 135 (23): 2071–2084.

https://doi.org/10.1182/blood.2019002227

Published: 2020

Includes: Multimedia, Supplemental data

Journal Articles

Identifying Cytokine Biomarkers of Response to Pegylated-Interferon Therapy in Polycythemia Vera and Essential Thrombocythemia: Correlative Analysis from the MPN-RC 111/112 Trials

Andrew Dunbar, MD, Heidi E. Kosiorek, MS, Aishwarya Krishnan, Erin McGovern, BA, Young Park, BS, Minal A Patel, MPH, Rona Singer Weinberg, PhD, Abdulraheem Yacoub, MD, Amylou C. Dueck, PhD, John Mascarenhas, MD, Ross L. Levine, MD, Ronald Hoffman, MD, Raajit K. Rampal, MD PhD

Blood (2019) 134 (Supplement_1): 1661.

https://doi.org/10.1182/blood-2019-129571

Published: 2019

Journal Articles

The Vasculopathy in the Bone Marrow Microenvironment of Humanized Sickle Cell Mice Is Reversible By Blood Transfusion

Shin-Young Park, PhD, Alessandro Mattè, BSc,PhD, Yookyung Jung, PhD, Jina Ryu, PhD, Wilson Anand, Eun Young Anna Han, B.S., Min Liu, M.S., Carmine Carbone, Davide Melisi, Takashi Nagasawa, Charles Lin, PhD, Leslie E. Silberstein, MD, Lucia De Franceschi, MD

Blood (2019) 134 (Supplement_1): 2256.

https://doi.org/10.1182/blood-2019-123532

Published: 2019

Journal Articles

Arteriolar Neovasculogenesis and Sinusoidal Collapse Are Pathologic Features of the Hematopoietic Stem Cell Niche in Sickle Cell Disease (SCD) Mice

Shin-Young Park, PhD, Alessandro Mattè, PhD, Eun Young Anna Han, B.S., Min Liu, M.S., Jina Ryu, PhD, Lucia De Franceschi, MD, Leslie E. Silberstein, MD

Blood (2017) 130 (Supplement 1): 3522.

https://doi.org/10.1182/blood.V130.Suppl_1.3522.3522

Published: 2017

Journal Articles

Phase 1/2 Trial of Subcutaneously Administered Factor IX Variant CB2679d/ISU304: Pharmacokinetics and Activity

Chur Woo You, MDPhD, Ho-Jin Shin, MD, Howard Levy, MBBCh, PhD, Martin Lee, PhD, Seung-Beom Hong, PhD, Jamie Ellen Siegel, MD, June Young Park, MD

Blood (2017) 130 (Supplement 1): 87.

https://doi.org/10.1182/blood.V130.Suppl_1.87.87

Published: 2017

Journal Articles

Diagnostic and Prognostic Implications of Prohibitin Overexpression in Normal Karyotype Acute Myeloid Leukemia

Hye-Ran Kim, PhD, Jun Hyung Lee, MD, Min-Gu Kang, MD, Ra-Young Park, PhD, Moinul Md Hoque, B.S., Sol Jeong, B.S., Min-Seo Noh, B.S., Seok-Yong Choi, MD, PhD, Soo-Hyun Kim, MD, PhD, Jong-Hee Shin, MD, PhD, Soon-Pal Suh, MD, PhD, Myung-Geun Shin, MD, PhD

Blood (2016) 128 (22): 1714.

https://doi.org/10.1182/blood.V128.22.1714.1714

Published: 2016

Journal Articles

No Mutations of SF3B1 , U2AF1 , and SRSF2 spliceosomal Gene but Polymorphisms Associated with the Worse Prognosis in Multiple Myeloma

Min-Gu Kang, MD, Hye-Ran Kim, PhD, Jun Hyung Lee, MD, Thashma Pemmanda Ganapathy, M.S., Seung-Hyeon Yang, B.S., Moinul Hoque, B.S., Ra-Young Park, PhD, Seung Jung Kee, MD, PhD, Soo Hyun Kim, MD, PhD, Jong-Hee Shin, MD, PhD, Soon-Pal Suh, MD, PhD, Myung-Geun Shin, MD, PhD

Blood (2015) 126 (23): 4190.

https://doi.org/10.1182/blood.V126.23.4190.4190

Published: 2015

Journal Articles

Perivascular deletion of murine Rac reverses the ratio of marrow arterioles and sinusoid vessels and alters hematopoiesis in vivo

Marioara F. Ciuculescu, Shin-Young Park, Kimberly Canty, Ronald Mathieu, Leslie E. Silberstein, David A. Williams

Blood (2015) 125 (20): 3105–3113.

https://doi.org/10.1182/blood-2014-10-604892

Published: 2015

Includes: Multimedia, Supplemental data

Journal Articles

Ikaros is required to survive positive selection and to maintain clonal diversity during T-cell development in the thymus

Kevin W. Tinsley, Changwan Hong, Megan A. Luckey, Joo-Young Park, Grace Y. Kim, Hee-won Yoon, Hilary R. Keller, Andrew J. Sacks, Lionel Feigenbaum, Jung-Hyun Park

Blood (2013) 122 (14): 2358–2368.

https://doi.org/10.1182/blood-2012-12-472076

Published: 2013

Includes: Supplemental data

Journal Articles

FAK Regulates Progenitor B Cell Growth, Localization and Retention in Bone Marrow Microenvironments

Shin-Young Park, Peter Wolfram, John Manis, Hilary Beggs, Cesar Nombela-Arrieta, Gregory Pivarnik, Leslie E Silberstein, MD

Blood (2011) 118 (21): 1119.

https://doi.org/10.1182/blood.V118.21.1119.1119

Published: 2011

Journal Articles

Functional PU.1 in macrophages has a pivotal role in NF-κB activation and neutrophilic lung inflammation during endotoxemia

Manjula Karpurapu, Xuerong Wang, Jing Deng, Hyesuk Park, Lei Xiao, Ruxana T. Sadikot, Randall S. Frey, Ulrich A. Maus, Gye Young Park, Edward W. Scott, John W. Christman

Blood (2011) 118 (19): 5255–5266.

https://doi.org/10.1182/blood-2011-03-341123

Published: 2011

Includes: Supplemental data

Journal Articles

A Multi-Center, Open Label Study Evaluating the Efficacy of Iron Chelation Therapy with Deferasirox In Transfusional Iron Overload Patients with Myelodysplastic Syndromes or Aplastic Anemia Using Quantitative R 2 mri.

Yoo-Hong Min, Hyeoung Joon Kim, MD, PhD, Kyoo-Hyung Lee, M.D., PhD., Jae Hoon Lee, MD, PhD, Hee-Sook Park, Jin Seok Kim, Hyeok Shim, MD, Chu-Myung Seung, Chul Soo Kim, Jooseop Chung, MD, PhD, Myung Soo Hyun, Deog-Yeon Jo, MD, PhD, Chul Won Jung, Sang Kyun Sohn, Hwi-Joong Yoon, MD, PhD, Byung Soo Kim, Young-Don Joo, Chi-Young Park

Blood (2010) 116 (21): 1125.

https://doi.org/10.1182/blood.V116.21.1125.1125

Published: 2010

NARROW

TMPRSS6 Antisense Oligonucleotide Therapy Reverses Inflammation in Jak2 V617F Mutant Mice

CXCL8/CXCR2 signaling mediates bone marrow fibrosis and is a therapeutic target in myelofibrosis

Jak2 V617F Reversible Activation Shows an Essential Requirement for Jak2 V617F in Myeloproliferative Neoplasms (MPNs)

The Second Generation Type II JAK2 Inhibitor, AJ1-10502, Demonstrates Enhanced Selectivity, Improved Therapeutic Efficacy and Reduced Mutant Cell Fraction Compared to Type I JAK2 Inhibitors in Models of Myeloproliferative Neoplasms (MPNs)

Aryl hydrocarbon receptor–targeted therapy for CD4 + T cell–mediated idiopathic pneumonia syndrome in mice

Genomic profiling identifies somatic mutations predicting thromboembolic risk in patients with solid tumors

Increased Interleukin-8 (IL8)-CXCR2 Signaling Promotes Progression of Bone Marrow Fibrosis in Myeloproliferative Neoplasms

Pathologic angiogenesis in the bone marrow of humanized sickle cell mice is reversed by blood transfusion

Identifying Cytokine Biomarkers of Response to Pegylated-Interferon Therapy in Polycythemia Vera and Essential Thrombocythemia: Correlative Analysis from the MPN-RC 111/112 Trials

The Vasculopathy in the Bone Marrow Microenvironment of Humanized Sickle Cell Mice Is Reversible By Blood Transfusion

Arteriolar Neovasculogenesis and Sinusoidal Collapse Are Pathologic Features of the Hematopoietic Stem Cell Niche in Sickle Cell Disease (SCD) Mice

Phase 1/2 Trial of Subcutaneously Administered Factor IX Variant CB2679d/ISU304: Pharmacokinetics and Activity

Diagnostic and Prognostic Implications of Prohibitin Overexpression in Normal Karyotype Acute Myeloid Leukemia

Comparison of Molecular Kinetics after the First and Second Imatinib Discontinuation: Results from the KID Study

No Mutations of SF3B1 , U2AF1 , and SRSF2 spliceosomal Gene but Polymorphisms Associated with the Worse Prognosis in Multiple Myeloma

Perivascular deletion of murine Rac reverses the ratio of marrow arterioles and sinusoid vessels and alters hematopoiesis in vivo

Ikaros is required to survive positive selection and to maintain clonal diversity during T-cell development in the thymus

FAK Regulates Progenitor B Cell Growth, Localization and Retention in Bone Marrow Microenvironments

Functional PU.1 in macrophages has a pivotal role in NF-κB activation and neutrophilic lung inflammation during endotoxemia

A Multi-Center, Open Label Study Evaluating the Efficacy of Iron Chelation Therapy with Deferasirox In Transfusional Iron Overload Patients with Myelodysplastic Syndromes or Aplastic Anemia Using Quantitative R 2 mri.

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American Society of Hematology

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American Society of Hematology

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