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Yookyung Jung
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Journal Articles

Proton export alkalinizes intracellular pH and reprograms carbon metabolism to drive normal and malignant cell growth

Cheuk Him Man, Francois E. Mercier, Nian Liu, Wentao Dong, Gregory Stephanopoulos, Li Jiang, Yookyung Jung, Charles P. Lin, Anskar Y. H. Leung, David T. Scadden
Journal: Blood
Blood (2022) 139 (4): 502–522.
https://doi.org/10.1182/blood.2021011563
Published: 2022
Includes: Supplemental data
Journal Articles

Pathologic angiogenesis in the bone marrow of humanized sickle cell mice is reversed by blood transfusion

Shin-Young Park, Alessandro Matte, Yookyung Jung, Jina Ryu, Wilson Babu Anand, Eun-Young Han, Min Liu, Carmine Carbone, Davide Melisi, Takashi Nagasawa, Joseph J. Locascio, Charles P. Lin, Leslie E. Silberstein, Lucia De Franceschi
Journal: Blood
Blood (2020) 135 (23): 2071–2084.
https://doi.org/10.1182/blood.2019002227
Published: 2020
Includes: Multimedia, Supplemental data
Journal Articles

The Vasculopathy in the Bone Marrow Microenvironment of Humanized Sickle Cell Mice Is Reversible By Blood Transfusion

Shin-Young Park, PhD, Alessandro Mattè, BSc,PhD, Yookyung Jung, PhD, Jina Ryu, PhD, Wilson Anand, Eun Young Anna Han, B.S., Min Liu, M.S., Carmine Carbone, Davide Melisi, Takashi Nagasawa, Charles Lin, PhD, Leslie E. Silberstein, MD, Lucia De Franceschi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2256.
https://doi.org/10.1182/blood-2019-123532
Published: 2019
Journal Articles

Epigenetic Activation of the pH Regulator MCT4 in Acute Myeloid Leukemia Exploits a Fundamental Metabolic Process of Enhancing Cell Growth through Proton Shifting

Cheuk-Him Man, David T. Scadden, MD, Francois Mercier, MD FRCPC, Nian Liu, Wentao Dong, Gregory Stephanopoulos, PhD, Li Jiang, PhD, Yookyung Jung, PhD, Charles Lin, PhD, Anskar Y.-H. Leung, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3765.
https://doi.org/10.1182/blood-2019-123604
Published: 2019
Journal Articles

Distinct Bone Marrow Blood Vessels Differentially Regulate Normal and Malignant Hematopoietic Stem and Progenitor Cells

Tomer Itkin, PhD, Shiri Gur Cohen, PhD, Joel A. Spencer, PhD, Amir Schajnovitz, Saravana K. Ramasamy, PhD, Anjali P. Kusumbe, PhD, Yookyung Jung, PhD, Guy Ledergor, MD, Idan Milo, PhD, Michael Gustave Poulos, PhD, Maria Garcia Fernandez, PhD, Alexander Kalinkovich, MDPhD, Aya Ludin, Orit Kollet, PhD, Guy Shakhar, PhD, Simon Mendez-Ferrer, PhD, Jason M. Butler, PhD, Shahin Rafii, MD, Ralf H. Adams, PhD, David T. Scadden, MD, Charles P. Lin, Tsvee Lapidot, PhD
Journal: Blood
Blood (2015) 126 (23): 664.
https://doi.org/10.1182/blood.V126.23.664.664
Published: 2015