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Erin McGovern
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Journal Articles

TP53 Alterations Confer Increased Risk of Leukemic Transformation and Worse Survival As Compared to High Molecular Risk Mutations in Patients with Myeloproliferative Neoplasms

Shivani Handa, Yosef Joseph Rene Amel Riazat-Kesh, Richard J Butterfield, Ganesh Sivakumar, Sangeetha Venugopal, Erin McGovern, Jonathan Feld, Douglas Tremblay, Sebastian Elghaity-Beckley, Marina Kremyanskaya, John O. Mascarenhas, Blake Langlais, Gina L. Mazza, Daniel I. Nathan, Joseph Tripodi, Vesna Najfeld, Amylou C Dueck, Raajit Rampal, Ronald Hoffman, Bridget Kelly Marcellino
Journal: Blood
Blood (2024) 144 (Supplement 1): 243.
https://doi.org/10.1182/blood-2024-206688
Published: 2024
Journal Articles

CXCL8/CXCR2 signaling mediates bone marrow fibrosis and is a therapeutic target in myelofibrosis

Andrew J. Dunbar, Dongjoo Kim, Min Lu, Mirko Farina, Robert L. Bowman, Julie L. Yang, Young Park, Abdul Karzai, Wenbin Xiao, Zach Zaroogian, Kavi O’Connor, Shoron Mowla, Francesca Gobbo, Paola Verachi, Fabrizio Martelli, Giuseppe Sarli, Lijuan Xia, Nada Elmansy, Maria Kleppe, Zhuo Chen, Yang Xiao, Erin McGovern, Jenna Snyder, Aishwarya Krishnan, Corrine Hill, Keith Cordner, Anouar Zouak, Mohamed E. Salama, Jayden Yohai, Eric Tucker, Jonathan Chen, Jing Zhou, Timothy McConnell, Anna R. Migliaccio, Richard Koche, Raajit Rampal, Rong Fan, Ross L. Levine, Ronald Hoffman
Journal: Blood
Blood (2023) 141 (20): 2508–2519.
https://doi.org/10.1182/blood.2022015418
Published: 2023
Includes: Supplemental data
Journal Articles

A randomized phase 3 trial of interferon-α vs hydroxyurea in polycythemia vera and essential thrombocythemia

Clinical Trials & Observations
John Mascarenhas, Heidi E. Kosiorek, Josef T. Prchal, Alessandro Rambaldi, Dmitriy Berenzon, Abdulraheem Yacoub, Claire N. Harrison, Mary Frances McMullin, Alessandro M. Vannucchi, Joanne Ewing, Casey L. O'Connell, Jean-Jacques Kiladjian, Adam J. Mead, Elliott F. Winton, David S. Leibowitz, Valerio De Stefano, Murat O. Arcasoy, Craig M. Kessler, Rosalind Catchatourian, Damiano Rondelli, Richard T. Silver, Andrea Bacigalupo, Arnon Nagler, Marina Kremyanskaya, Max F. Levine, Juan E. Arango Ossa, Erin McGovern, Lonette Sandy, Mohamad E. Salama, Vesna Najfeld, Joseph Tripodi, Noushin Farnoud, Alexander V. Penson, Rona Singer Weinberg, Leah Price, Judith D. Goldberg, Tiziano Barbui, Roberto Marchioli, Gianni Tognoni, Raajit K. Rampal, Ruben A. Mesa, Amylou C. Dueck, Ronald Hoffman
Journal: Blood
Blood (2022) 139 (19): 2931–2941.
https://doi.org/10.1182/blood.2021012743
Published: 2022
Includes: Supplemental data
Journal Articles

Treatment of Myelofibrosis Patients with the TGF-β 1/3 Inhibitor AVID200 (MPN-RC 118) Induces a Profound Effect on Platelet Production

John Mascarenhas, Heidi E. Kosiorek, Rupali Bhave, Jeanne M. Palmer, Andrew T. Kuykendall, Ruben A. Mesa, Raajit Rampal, Aaron T. Gerds, Abdulraheem Yacoub, Kristen M. Pettit, Moshe Talpaz, Rami S. Komrokji, Marina Kremyanskaya, Agapito Gonzalez, Frank Fabris, Lonette Sandy, Kathryn Johnson, Mikaela Doughtery, Erin McGovern, Juan Arango Ossa, Dylan Domenico, Noushin Farnoud, Anna Rita Migliaccio, Mohamed E Salama, Rona Singer Weinberg, Amy Kong, Vesna Najfeld, Carolyn Mead-Harvey, Amylou C. Dueck, Lilian Varricchio, Ronald Hoffman
Journal: Blood
Blood (2021) 138 (Supplement 1): 142.
https://doi.org/10.1182/blood-2021-148995
Published: 2021
Journal Articles

Analysis of the Global Methylation Profile of Accelerated and Blast Phase Myeloproliferative Neoplasms and Its Association with Response to Decitabine-Based Therapy

Raajit K. Rampal, MD PhD, Qin Yang, Richard P. Koche, PhD, Erin McGovern, BA, Christopher Famulare, MS, Rona Singer Weinberg, PhD, John Mascarenhas, MD, Ross L. Levine, MD, Ronald Hoffman, MD, Maria E. Figueroa, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 18–20.
https://doi.org/10.1182/blood-2020-139505
Published: 2020
Journal Articles

Molecular Predictors and Effectiveness of Measurable Residual Disease (MRD) Eradication with Chemotherapy and Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia

Maximilian Stahl, MD, Andriy Derkach, PhD, Christopher Famulare, MS, Christina Cho, MD, Sean Devlin, PhD, Noushin Farnoud, PhD, Kamal Menghrajani, MD, Minal A Patel, MPH, Sheng F Cai, MDPhD, Mark B. Geyer, MD, Andrew Dunbar, MD, Zachary D. Epstein-Peterson, MD, Erin McGovern, BA, Jessica Schulman, BSc, Jacob L Glass, MDPhD, Justin Taylor, MD, Aaron D Viny, MDMS, Eytan M. Stein, MD, Bartlomiej Getta, FRCPA, FRACP, MBBS, Maria E. Arcila, MD, Ross L. Levine, MD, Juliet Barker, MBBS, Brian C. Shaffer, MD, Esperanza B. Papadopoulos, MD, Boglarka Gyurkocza, MD, Miguel-Angel Perales, MD, Omar Abdel-Wahab, MD, Elli Papaemmanuil, PhD, Sergio A. Giralt, MD, Yanming Zhang, MD, Mikhail Roshal, MD PhD, Martin S. Tallman, MD, Aaron D Goldberg, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 18–20.
https://doi.org/10.1182/blood-2020-137552
Published: 2020
Journal Articles

Landscape of TP53 Mutations in MPN

Noushin Farnoud, PhD, Christopher Famulare, MS, Elli Papaemmanuil, PhD, Erin McGovern, BA, Juan Medina, MS, Juan E. Arango Ossa, BS, Raajit K. Rampal, MD PhD, Bing Li, MD, Ross L. Levine, MD, John Mascarenhas, MD, Rona Singer Weinberg, PhD, Minal A Patel, MPH, Ronald Hoffman, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1681.
https://doi.org/10.1182/blood-2019-132014
Published: 2019
Journal Articles

Identifying Cytokine Biomarkers of Response to Pegylated-Interferon Therapy in Polycythemia Vera and Essential Thrombocythemia: Correlative Analysis from the MPN-RC 111/112 Trials

Andrew Dunbar, MD, Heidi E. Kosiorek, MS, Aishwarya Krishnan, Erin McGovern, BA, Young Park, BS, Minal A Patel, MPH, Rona Singer Weinberg, PhD, Abdulraheem Yacoub, MD, Amylou C. Dueck, PhD, John Mascarenhas, MD, Ross L. Levine, MD, Ronald Hoffman, MD, Raajit K. Rampal, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1661.
https://doi.org/10.1182/blood-2019-129571
Published: 2019
Journal Articles

The Genetic Architecture of Myeloproliferative Neoplasms-Blast Phase (MPN-BP) Stem Cells

Xiaoli Wang, MD PhD, Raajit K. Rampal, MD PhD, Cing Siang Hu, Noushin Farnoud, PhD, Christopher Famulare, MS, Minal A Patel, MPH, Erin McGovern, BA, Ronald Hoffman, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1677.
https://doi.org/10.1182/blood-2019-128836
Published: 2019
Journal Articles

Evaluation of Tagraxofusp (SL-401) Alone and in Combination with Ruxolitinib for the Treatment of Myeloproliferative Neoplasms

Aishwarya Krishnan, Maria Pagane, Mikhail Roshal, MD PhD, Erin McGovern, BA, Zoe Stone-Molloy, Janice Chen, PhD, Christopher Brooks, PhD, Ross L. Levine, MD, Raajit K. Rampal, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2967.
https://doi.org/10.1182/blood-2019-129397
Published: 2019
Journal Articles

De Novo Myelodysplastic Syndromes in Patients 20-50 Years Old Characterized By Frequent Mutations in TP53 and Transcription-Related Genes

Zachary D. Epstein-Peterson, MD, Barbara Spitzer, MD, Joseph McCarter, PhD, Erin McGovern, BA, Ross L. Levine, MD, Martin S. Tallman, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2708.
https://doi.org/10.1182/blood-2019-123400
Published: 2019
Journal Articles

Expansion of Prior Existing TP53 Mutated Clones in Polycythemia Vera Patients Treated with Idasanutlin

Bridget Marcellino, MD PhD, Bruno Cassinat, PharmD, PhD, Noushin Farnoud, PhD, Min Lu, PhD, Emmanuelle Verger, PhD, Erin McGovern, BA, Minal A Patel, MPH, Heidi E. Kosiorek, MS, Meenakshi Mehrotra, PhD, Jane Houldsworth, PhD, Amylou C. Dueck, PhD, Michael Rossi, PhD, Jean-Jacques Kiladjian, MD PhD, Raajit K. Rampal, MD PhD, John Mascarenhas, MD, Ronald Hoffman, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 838.
https://doi.org/10.1182/blood-2019-128342
Published: 2019
Journal Articles

Evaluation of Combination Tagraxofusp (SL-401) and Hypomethylating Agent (HMA) Therapy for the Treatment of Chronic Myelomonocytic Leukemia (CMML)

Aishwarya Krishnan, Bing Li, MD, Maria Pagane, Erin McGovern, BA, Zoe Stone-Molloy, Janice Chen, PhD, Christopher Brooks, PhD, Ross L. Levine, MD, Raajit K. Rampal, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1809.
https://doi.org/10.1182/blood-2018-99-120035
Published: 2018
Journal Articles

Loss of Plasmacytoid Dendritic Cell Differentiation Is Highly Predictive for Persistent Measurable Residual Disease and Poor Outcomes in Acute Myeloid Leukemia

Wenbin Xiao, MD, Aaron D Goldberg, MD PhD, Christopher Famulare, MS, Sean Delvin, Minal Patel, BA, Erin McGovern, BA, Akshar Patel, BA, Jessica Schulman, Andrew Dunbar, MD, Zachary D. Epstein-Peterson, MD, Kamal Menghrajani, MD, Bartlomiej Getta, Sheng Cai, MD PhD, Mark Blaine Geyer, MD, Jacob L Glass, MD PhD, Justin Taylor, MD, Aaron D Viny, MD MS, Ross L. Levine, MD, Yanming Zhang, MD, Martin S. Tallman, MD, Mikhail Roshal, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1523.
https://doi.org/10.1182/blood-2018-99-112591
Published: 2018
Journal Articles

Molecular Predictors and Current Management of Minimal Residual Disease (MRD) Following Induction Chemotherapy for Acute Myeloid Leukemia (AML)

Aaron D Goldberg, MDPhD, Christopher Famulare, MS, Sean M Devlin, PhD, Noushin Farnoud, PhD, Kamal Menghrajani, MD, Minal Patel, BA, Sheng Cai, MD PhD, Andrew Dunbar, MD, Zachary D. Epstein-Peterson, MD, Erin McGovern, BA, Jessica Schulman, Jacob L Glass, MDPhD, Justin Taylor, MD, Aaron D Viny, MDMS, Bartlomiej Getta, FRCPA, FRACP, MBBS, Maria E Arcila, MD, Ross L. Levine, MD, Brian C. Shaffer, MD, Boglarka Gyurkocza, MD, Esperanza B. Papadopoulos, MD, Miguel-Angel Perales, MD, Elli Papaemmanuil, PhD, Sergio Giralt, MD, Yanming Zhang, MD, Mikhail Roshal, MD PhD, Martin S. Tallman, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 292.
https://doi.org/10.1182/blood-2018-99-112938
Published: 2018
Journal Articles

Early Detection and Molecular Characterization of Therapy-Related Leukemia in Children Reveals Patterns of Disease Transformation and Guides Future Surveillance Protocols

Barbara Spitzer, MD, Gunes Gundem, PhD, Noushin Farnoud, PhD, Nathan Millard, MD, Erin McGovern, BA, Minal Patel, BA, Max Levine, MS, Juan Medina, MS, Yangyu Zhou, BS, Juan E. Arango Ossa, BS, Michael Francis Walsh, MD, Ross L. Levine, MD, Irene Y. Cheung, ScD, Scott A. Armstrong, MD PhD, Nai-Kong V. Cheung, MD PhD, Elli Papaemmanuil, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 291.
https://doi.org/10.1182/blood-2018-99-120005
Published: 2018