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Juan Arango Ossa
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Journal Articles

Clonal persistence and early cooperative mutations shape transformation in myelofibrosis

Free
Noushin Farnoud, Kamal Menghrajani, Paola Guglielmelli, Christopher Famulare, Erin McGovern, Giuseppe Gaetano Loscocco, Andriy Derkach, Andrew Dunbar, Naseema Gangat, Vikas Gupta, Andrea Arruda, Taghi Manshouri, Srdan Verstovsek, Andrew Kuykendall, Vincent Ho, Auro Viswabandya, Joachim Deeg, Thomas Monahan, Tania Jain, Jeanne Palmer, Alla Keyzner, Aaron Gerds, Alexandra Gomez-Arteaga, Nikolai Podoltsev, Roni Tamari, Helen Ajufo, Satyajit Kosuri, Haris Ali, Idoroenyi Amanam, Jordan Chervin, Minal Patel, Jesús Gutiérrez-Abril, Sarun Sereewattanawoot, Juan Arango Ossa, Francesco Passamonti, Francesco Maura, Maymona Abdelmagid, Ahmed Abdelrheem, Yassin Bashir, Muhammad Yousuf, Animesh Pardanani, Kapila Viges, David Shoultz, Rick Winneker, Omar Abdel-Wahab, John Mascarenhas, Ronald Hoffman, Ross Levine, Elli Papaemmanuil, Alessandro Vannucchi, Ayalew Tefferi, Raajit Rampal
Journal: Blood
Blood (2025) 146 (Supplement 1): 2046.
https://doi.org/10.1182/blood-2025-2046
Published: 2025
Journal Articles

Feasibility and utility of unmatched whole-genome sequencing (uWGS)  for pediatric acute leukemias: An analysis of leukemia precision-based therapy (LEAP) study samples

Free
Jesús Gutiérrez-Abril, Dylan Domenico, Gunes Gundem, Juan Arango Ossa, Anu Amallraja, Konstantinos Liosis, Sarah Tasian, Todd Cooper, Melinda Pauly, Kelly Maloney, Michael Burke, Stacy Cooper, Nathan Gossai, Jennifer McNeer, Justine Kahn, Nobuko Hijiya, Matthew Barth, Jeffrey Magee, Mignon Loh, Kimberly Stegmaier, Marian Harris, Emily Stockfisch, Francesco Maura, Andrew Kung, Elli Papaemmanuil, Maria Luisa Sulis, Yana Pikman, Neerav Shukla
Journal: Blood
Blood (2025) 146 (Supplement 1): 2561.
https://doi.org/10.1182/blood-2025-2561
Published: 2025
Journal Articles

Tracking the evolution of therapy-related myeloid neoplasms using chemotherapy signatures

Free
Benjamin Diamond, Bachisio Ziccheddu, Kylee Maclachlan, Justin Taylor, Eileen Boyle, Juan Arango Ossa, Jacob Jahn, Maurizio Affer, Tulasigeri M. Totiger, David Coffey, Namrata Chandhok, Justin Watts, Luisa Cimmino, Sydney X. Lu, Niccolò Bolli, Kelly Bolton, Heather Landau, Jae H. Park, Karuna Ganesh, Andrew McPherson, Mikkael A. Sekeres, Alexander Lesokhin, David J. Chung, Yanming Zhang, Caleb Ho, Mikhail Roshal, Jeffrey Tyner, Stephen Nimer, Elli Papaemmanuil, Saad Usmani, Gareth Morgan, Ola Landgren, Francesco Maura
Journal: Blood
Blood (2023) 141 (19): 2359–2371.
https://doi.org/10.1182/blood.2022018244
Published: 2023
Includes: Supplemental data
Journal Articles

Treatment of Myelofibrosis Patients with the TGF-β 1/3 Inhibitor AVID200 (MPN-RC 118) Induces a Profound Effect on Platelet Production

Free
John Mascarenhas, Heidi E. Kosiorek, Rupali Bhave, Jeanne M. Palmer, Andrew T. Kuykendall, Ruben A. Mesa, Raajit Rampal, Aaron T. Gerds, Abdulraheem Yacoub, Kristen M. Pettit, Moshe Talpaz, Rami S. Komrokji, Marina Kremyanskaya, Agapito Gonzalez, Frank Fabris, Lonette Sandy, Kathryn Johnson, Mikaela Doughtery, Erin McGovern, Juan Arango Ossa, Dylan Domenico, Noushin Farnoud, Anna Rita Migliaccio, Mohamed E Salama, Rona Singer Weinberg, Amy Kong, Vesna Najfeld, Carolyn Mead-Harvey, Amylou C. Dueck, Lilian Varricchio, Ronald Hoffman
Journal: Blood
Blood (2021) 138 (Supplement 1): 142.
https://doi.org/10.1182/blood-2021-148995
Published: 2021
Journal Articles

Isogenic MDS-RS Patient-Derived iPSCs Define the Mis-Spliced Transcript Repertoire and Chromatin Landscape of SF3B1-Mutant Hematopoietic Stem/Progenitor Cells

Free
George Asimomitis, André G. Deslauriers, Andriana G. Kotini, Elsa Bernard, Davide Esposito, Malgorzata Olszewska, Nikolaos Spyrou, Juan Arango Ossa, Teresa Mortera-Blanco, Richard Koche, Stuart Aaronson, Eva Hellström-Lindberg, Elli Papaemmanuil, Eirini P. Papapetrou
Journal: Blood
Blood (2021) 138 (Supplement 1): 147.
https://doi.org/10.1182/blood-2021-149830
Published: 2021
Journal Articles

Chemotherapy-Related Mutational Signatures Reveal the Origins of Therapy-Related Myeloid Neoplasms

Free
Benjamin Diamond, Bachisio Ziccheddu, Eileen M Boyle, Kylee H Maclachlan, Juan Arango Ossa, Justin Taylor, Justin Watts, Sydney X. Lu, Venkata D Yellapantula, Christopher Famulare, Monika Chojnacka, Arjun Raj Rajanna, Emilia Mason, David G. Coffey, James E. Hoffman, Dickran Kazandjian, Terrence J Bradley, Menglei Zhu, Niccolo Bolli, Elli Papaemmanuil, Kelly L. Bolton, Michael Scordo, Oscar B Lahoud, Eytan M. Stein, Craig S. Sauter, Hani Hassoun, Sham Mailankody, Neha Korde, Malin Hultcrantz, Urvi A Shah, Gunjan L Shah, Jae H Park, Heather J Landau, Karuna Ganesh, Mikkael A. Sekeres, Stephen Nimer, David J. Chung, Caleb Ho, Mikhail Roshal, Alexander Lesokhin, Gareth J. Morgan, Ola Landgren, Francesco Maura
Journal: Blood
Blood (2021) 138 (Supplement 1): 3271.
https://doi.org/10.1182/blood-2021-145927
Published: 2021