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Journal Articles

Codon-Specific Differences in RAS Mutations in AML and Differential Response to Therapeutic Agents

Annabelle J Anandappa, Vidushi Trivedi, Tiffany Merlinsky, Nicole Delgaudio, Emily Guzzardi, Ashley Wooten, Daniel Starczynowski, Robert L. Bowman, Ross Levine, Linde A. Miles

Blood (2024) 144 (Supplement 1): 2713.

https://doi.org/10.1182/blood-2024-205218

Published: 2024

Journal Articles

Leukemia secondary to myeloproliferative neoplasms

Andrew J. Dunbar, Raajit K. Rampal, Ross Levine

Blood (2020) 136 (1): 61–70.

https://doi.org/10.1182/blood.2019000943

Published: 2020

Journal Articles

Janus kinase inhibition lessens inflammation and ameliorates disease in murine models of hemophagocytic lymphohistiocytosis

Rupali Das, Peng Guan, Leslee Sprague, Katherine Verbist, Paige Tedrick, Qi Angel An, Cheng Cheng, Makoto Kurachi, Ross Levine, E. John Wherry, Scott W. Canna, Edward M. Behrens, Kim E. Nichols

Blood (2016) 127 (13): 1666–1675.

https://doi.org/10.1182/blood-2015-12-684399

Published: 2016

Includes: Supplemental data

Journal Articles

Distinct effects of concomitant Jak2V617F expression and Tet2 loss in mice promote disease progression in myeloproliferative neoplasms

Edwin Chen, Rebekka K. Schneider, Lawrence J. Breyfogle, Emily A. Rosen, Luke Poveromo, Shannon Elf, Amy Ko, Kristina Brumme, Ross Levine, Benjamin L. Ebert, Ann Mullally

Blood (2015) 125 (2): 327–335.

https://doi.org/10.1182/blood-2014-04-567024

Published: 2015

Includes: Supplemental data

Journal Articles

Antagonistic activities of the immunomodulator and PP2A-activating drug FTY720 (Fingolimod, Gilenya) in Jak2-driven hematologic malignancies

Blood (2013) 122 (11): 1923–1934.

https://doi.org/10.1182/blood-2013-03-492181

Published: 2013

Includes: Supplemental data

Journal Articles

Ddx18 is essential for cell-cycle progression in zebrafish hematopoietic cells and is mutated in human AML

Elspeth M. Payne, Niccolò Bolli, Jennifer Rhodes, Omar I. Abdel-Wahab, Ross Levine, Cyrus V. Hedvat, Richard Stone, Arati Khanna-Gupta, Hong Sun, John P. Kanki, Hanna T. Gazda, Alan H. Beggs, Finbarr E. Cotter, A. Thomas Look

Blood (2011) 118 (4): 903–915.

https://doi.org/10.1182/blood-2010-11-318022

Published: 2011

Includes: Multimedia, Supplemental data

Journal Articles

MYBL2 Is a Candidate Tumor Suppressor Gene In MDS

Stefan Heinrichs, Lily Conover, Carlos E. Bueso-Ramos, Outi Kilpivaara, Ross Levine, MD, Kristen Stevenson, Donna Neuberg, ScD, Rafael Bejar, MD, PhD, Benjamin L. Ebert, MD, DPhil, Guillermo Garcia-Manero, MD, Hagop M. Kantarjian, MD, A. Thomas Look, MD

Blood (2010) 116 (21): 1865.

https://doi.org/10.1182/blood.V116.21.1865.1865

Published: 2010

Journal Articles

High Mitochondrial Membrane Potential Identifies Patients with Myeloproliferative Neoplasms with a More Aggressive Natural History

Jeffrey R Gardner, MBA, Omar Abdel-Wahab, Mark Frattini, MD, Joseph G Jurcic, MD, Kristina Knapp, Todd L. Rosenblat, MD, MS, Gerald A. Soff, MD, Ross Levine, MD, Mark Heaney, MD, PhD

Blood (2010) 116 (21): 1992.

https://doi.org/10.1182/blood.V116.21.1992.1992

Published: 2010

Journal Articles

Mir-9 Is Aberrantly Expressed In MPN Patients and Accelerates Erythropoietic Cell Growth and Differentiation

Xiaoqing Lin, Kim Rice, PhD, Martin Carroll, MD, Fabricio Costa, PhD, Outi Kilpivaara, Marcelo B. Soares, PhD, Ross Levine, MD, Jonathan D. Licht, MD

Blood (2010) 116 (21): 1983.

https://doi.org/10.1182/blood.V116.21.1983.1983

Published: 2010

Journal Articles

High Rates of Molecular Response After Long-Term Follow-up of Patients with Advanced Essential Thrombocythemia (ET) or Polycythemia Vera (PV) Treated with Pegylated Interferon-ALFA-2A (PEG-IFN-α-2A; PEGASYS)

Alfonso Quintás-Cardama, MD, Ross Levine, MD, Taghi Manshouri, Outi Kilpivaara, Hagop M. Kantarjian, MD, Srdan Verstovsek, MD, PhD

Blood (2010) 116 (21): 461.

https://doi.org/10.1182/blood.V116.21.461.461

Published: 2010

Journal Articles

High-Throughput Mutational Profiling In AML: Mutational Analysis of the ECOG E1900 Trial

Blood (2010) 116 (21): 851.

https://doi.org/10.1182/blood.V116.21.851.851

Published: 2010

Journal Articles

Concomitant Analysis of EZH2 and ASXL1 Mutations In Myelofibrosis, Chronic Myelomonocytic Leukemia and Blast-Phase Myeloproliferative Neoplasms

Omar Abdel-Wahab, Animesh Pardanani, MBBS, PhD, Jay Patel, Terra Lasho, MT, (ASCP), Adriana Heguy, Ross Levine, MD, Ayalew Tefferi, MD

Blood (2010) 116 (21): 3070.

https://doi.org/10.1182/blood.V116.21.3070.3070

Published: 2010

Journal Articles

Point Mutations In Myelodysplastic Syndromes Are Associated with Clinical Features and Are Independent Predictors of Overall Survival

Rafael Bejar, MD, PhD, Kristen Stevenson, Omar Abdel-Wahab, MD, McConkey Marie, PhD, Katherine Lin, James Randall McAuley, Kevin Cheung, MD, Naomi Galili, Ph.D., Guillermo Garcia-Manero, MD, Hagop Kantarjian, MD, Azra Raza, MD, Ross Levine, MD, Donna Neuberg, ScD, Benjamin L. Ebert, MD, DPhil

Blood (2010) 116 (21): 300.

https://doi.org/10.1182/blood.V116.21.300.300

Published: 2010

Journal Articles

Co-Treatment with JAK2 Inhibitor TG101209 and Panobinostat or hsp90 Inhibitor AUY922 Attenuates Mutant JAK2-V617F Levels and Activity in Human Myeloproliferative Disorder Cells

Yongchao Wang, Warren Fiskus, Kavita Natarajan, Anand Jillella, Cornelia Quadt, Peter Ataja, Ross Levine, Kapil N. Bhalla

Blood (2008) 112 (11): 3739.

https://doi.org/10.1182/blood.V112.11.3739.3739

Published: 2008

Journal Articles

Systematic Genomic Screen for Tyrosine Kinase Mutations in CLL.

Jennifer R. Brown, MD, PhD, Ross Levine, MD, Elke Raderschall, PhD, Christina Thompson, BS, D. Gary Gilliland, MD, Arnold S. Freedman, MD

Blood (2007) 110 (11): 2069.

https://doi.org/10.1182/blood.V110.11.2069.2069

Published: 2007

Journal Articles

High-Throughput Sequence Analysis of the Tyrosine Kinome in Acute Myeloid Leukemia.

Marc Loriaux, Ross Levine, Jeffrey Tyner, Stephan Frohling, Claudia Scholl, Eric Stoffregen, Gerlinde Wernig, Heidi Erickson, Chris Eide, Roland Berger, Olivier Bernard, James Griffin, Richard Stone, Matthew Meyerson, Michael Heinrich, Michael Deininger, Gary Gilliland, Brian Druker

Blood (2007) 110 (11): 886.

https://doi.org/10.1182/blood.V110.11.886.886

Published: 2007

Journal Articles

The JAK2 Kinase Inhibitor LS104 Induces Growth-Arrest and Apoptosis in JAK2V617F Positive Cells.

Daniel B. Lipka, MD, Linda S. Hoffmann, MSc, Florian Heidel, MD, Boyka Markova, PhD, Stefan Kasper, MD, Frank Breitenbuecher, PhD, Thomas Kindler, MD, Ross Levine, MD, Joseph Elliot, PhD, Christoph Huber, MD, Thomas Fischer, MD

Blood (2007) 110 (11): 3544.

https://doi.org/10.1182/blood.V110.11.3544.3544

Published: 2007

Journal Articles

Large Regions of Uniparental Disomy (UPD) Establish Clonal Hematopoietic Stem Cell Selection in a Subset of Myelodysplastic Syndrome (MDS) Patients with Normal Bone Marrow Cell Karyotypes.

Stefan Heinrichs, PhD, Rima V. Kulkarni, Carlos E. Bueso-Ramos, MD, Mignon Loh, MD, Ross Levine, MD, Cheng Li, Donna S. Neuberg, Steve M. Kornblau, MD, Jean-Pierre Issa, MD, D. Gary Gilliland, MD, Elihu H. Estey, MD, A. Thomas Look, MD

Blood (2007) 110 (11): 120.

https://doi.org/10.1182/blood.V110.11.120.120

Published: 2007

Journal Articles

MPL W515L/K and JAK2 V617F Mutations: Single Colony Studies, Lineage Restriction, and Chronology of Clonal Emergence.

Animesh Pardanani, MD, PhD, Terra Lasho, Christy Finke, Ruben Mesa, MD, William Hogan, MD, Ross Levine, MD, D. Gary Gilliland, MD, PhD, Ayalew Tefferi, MD

Blood (2006) 108 (11): 116.

https://doi.org/10.1182/blood.V108.11.116.116

Published: 2006

Journal Articles

High Resolution SNP Arrays and Correlation with Expression Arrays Identify Novel Genomic Aberrations and Potential Disease Genes in Polycythemia Vera and Other Myeloproliferative Disorders.

Weijia Zhang, PhD, Windy Berkofsky-Fessler, MPhil, Ross Levine, MD, Yezhou Sun, MS, D. Gary Gilliland, MD, Jonathan D. Licht, MD

Blood (2006) 108 (11): 359.

https://doi.org/10.1182/blood.V108.11.359.359

Published: 2006

NARROW

Codon-Specific Differences in RAS Mutations in AML and Differential Response to Therapeutic Agents

Leukemia secondary to myeloproliferative neoplasms

Janus kinase inhibition lessens inflammation and ameliorates disease in murine models of hemophagocytic lymphohistiocytosis

Distinct effects of concomitant Jak2V617F expression and Tet2 loss in mice promote disease progression in myeloproliferative neoplasms

Antagonistic activities of the immunomodulator and PP2A-activating drug FTY720 (Fingolimod, Gilenya) in Jak2-driven hematologic malignancies

Ddx18 is essential for cell-cycle progression in zebrafish hematopoietic cells and is mutated in human AML

MYBL2 Is a Candidate Tumor Suppressor Gene In MDS

High Mitochondrial Membrane Potential Identifies Patients with Myeloproliferative Neoplasms with a More Aggressive Natural History

Mir-9 Is Aberrantly Expressed In MPN Patients and Accelerates Erythropoietic Cell Growth and Differentiation

High Rates of Molecular Response After Long-Term Follow-up of Patients with Advanced Essential Thrombocythemia (ET) or Polycythemia Vera (PV) Treated with Pegylated Interferon-ALFA-2A (PEG-IFN-α-2A; PEGASYS)

High-Throughput Mutational Profiling In AML: Mutational Analysis of the ECOG E1900 Trial

Concomitant Analysis of EZH2 and ASXL1 Mutations In Myelofibrosis, Chronic Myelomonocytic Leukemia and Blast-Phase Myeloproliferative Neoplasms

Point Mutations In Myelodysplastic Syndromes Are Associated with Clinical Features and Are Independent Predictors of Overall Survival

Co-Treatment with JAK2 Inhibitor TG101209 and Panobinostat or hsp90 Inhibitor AUY922 Attenuates Mutant JAK2-V617F Levels and Activity in Human Myeloproliferative Disorder Cells

Systematic Genomic Screen for Tyrosine Kinase Mutations in CLL.

High-Throughput Sequence Analysis of the Tyrosine Kinome in Acute Myeloid Leukemia.

The JAK2 Kinase Inhibitor LS104 Induces Growth-Arrest and Apoptosis in JAK2V617F Positive Cells.

Large Regions of Uniparental Disomy (UPD) Establish Clonal Hematopoietic Stem Cell Selection in a Subset of Myelodysplastic Syndrome (MDS) Patients with Normal Bone Marrow Cell Karyotypes.

MPL W515L/K and JAK2 V617F Mutations: Single Colony Studies, Lineage Restriction, and Chronology of Clonal Emergence.

High Resolution SNP Arrays and Correlation with Expression Arrays Identify Novel Genomic Aberrations and Potential Disease Genes in Polycythemia Vera and Other Myeloproliferative Disorders.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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