1-10 of 10
Roger Briesewitz
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Antagonistic activities of the immunomodulator and PP2A-activating drug FTY720 (Fingolimod, Gilenya) in Jak2-driven hematologic malignancies

Joshua J. Oaks, Ramasamy Santhanam, Christopher J. Walker, Steve Roof, Jason G. Harb, Greg Ferenchak, Ann-Kathrin Eisfeld, James R. Van Brocklyn, Roger Briesewitz, Sahar A. Saddoughi, Kyosuke Nagata, Robert Bittman, Michael A. Caligiuri, Omar Abdel-Wahab, Ross Levine, Ralph B. Arlinghaus, Alfonso Quintas-Cardama, John M. Goldman, Jane Apperley, Alistair Reid, Dragana Milojkovic, Mark T. Ziolo, Guido Marcucci, Besim Ogretmen, Paolo Neviani, Danilo Perrotti
Journal: Blood
Blood (2013) 122 (11): 1923–1934.
https://doi.org/10.1182/blood-2013-03-492181
Published: 2013
Includes: Supplemental data
Journal Articles

Pharmacologic Restoration of PP2A Activity and Interference with the SET-PP2A Interplay by FTY720 and Its Non-Immunosuppressive Derivative as a Novel and Efficient Therapy for Ph-Negative Myeloproliferative Disorders

Joshua J Oaks, A. Mukhopadhyay, Ramasamy Santhanam, S. A Saddoughi, Christopher Walker, Paolo Neviani, Jason G Harb, Y. Ma, Srdan Verstovsek, MD, PhD, Guido Marcucci, MD, Roger Briesewitz, Robert Bittman, Ching-Shih Chen, Alfonso Quintas-Cardama, MD, Besim Ogretmen, Danilo Perrotti, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 775.
https://doi.org/10.1182/blood.V116.21.775.775
Published: 2010
Journal Articles

The Mll PTD and Flt3 ITD Double Knock-In Mouse Develops Acute Leukemia and Recapitulates Phenotypic, Molecular and Epigenetic Characteristics of the Counterpart Human Acute Myeloid Leukemia

Nicholas Zorko, Susan P. Whitman, PhD, Kelsie Bernot, PhD, Myntee T. Ngangana, Ronald Siebenaler, Shujun Liu, Ph.D., Yue-Zhong Wu, MS, Chidimma Kalu, Xiaoli Zhang, PhD, MS, David Jarjoura, PhD, Zhiliang Xie, MD, Kenneth K. Chan, PhD, Adrienne M. Dorrance, PhD, Benjamin H. Lee, MD, PhD, Roger Briesewitz, PhD, Danilo Perrotti, MD, PhD, Guido Marcucci, MD, Michael A. Caligiuri, MD
Journal: Blood
Blood (2010) 116 (21): 150.
https://doi.org/10.1182/blood.V116.21.150.150
Published: 2010
Journal Articles

FTY720 but Not Its Immunosuppressive Phosphorylated Form FTY720-P Exerts Anti-Leukemic Activity towards Ph(+) and Ph(−) Myeloproliferative Disorders through Reactivation of the PP2A Tumor Suppressor.

Joshua Oaks, BS, Paolo Neviani, PhD, A. Mukhopadhyay, Ramasamy Santhanam, PhD, Y. Ma, Charlene Mao, Guido Marcucci, MD, Ching-Shih Chen, Jorge Cortes, MD, Michael A. Caligiuri, M.D., Peter Hokland, Sr., Claudia Huettner, PhD, Steffen Koschmieder, MD, Jose Cancelas, MD, PhD, Roger Briesewitz, PhD, Ravi Bhatia, MD, Denis-Claude Roy, MD, Besim Ogretmen, PhD, Danilo Perrotti, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 3259.
https://doi.org/10.1182/blood.V114.22.3259.3259
Published: 2009
Journal Articles

Evidence of MicroRNA-29b and Sp1/NFκB-HDAC Regulatory Network for KIT Expression in KIT-Driven Acute Myeloid Leukemia (AML): Biologic and Therapeutic Implications.

Shujun Liu, PhD, Lai Chu Wu, PhD, Jiuxia Pang, BS, Ramasamy Santhanam, PhD, Sebastian Schwind, MD, Yue-Zhong Wu, MS, Christopher Hickey, MS, Jianhua Yu, PhD, Anjali Mishra, PhD, Heiko Becker, MD, Chenglong Li, PhD, Roger Briesewitz, PhD, Robert A. Baiocchi, MD, Kenneth K. Chan, PhD, Michael A. Caligiuri, MD, John C. Byrd, MD, Danilo Perrotti, MD, PhD, Ramiro Garzon, MD, Guido Marcucci, MD
Journal: Blood
Blood (2009) 114 (22): 938.
https://doi.org/10.1182/blood.V114.22.938.938
Published: 2009
Journal Articles

Fathoming Flt3

Roger Briesewitz
Journal: Blood
Blood (2009) 113 (17): 3889–3890.
https://doi.org/10.1182/blood-2009-02-205435
Published: 2009
Journal Articles

Stem cell factor and interleukin-2/15 combine to enhance MAPK-mediated proliferation of human natural killer cells

Don M. Benson, Jr, Jianhua Yu, Brian Becknell, Min Wei, Aharon G. Freud, Amy K. Ferketich, Rossana Trotta, Danilo Perrotti, Roger Briesewitz, Michael A. Caligiuri
Journal: Blood
Blood (2009) 113 (12): 2706–2714.
https://doi.org/10.1182/blood-2008-05-159285
Published: 2009
Journal Articles

Activating PP2A Tumor Suppressor Activity as a Potential Therapy for Treating Jak2 V617F-Driven Myeloproliferative Disorders.

Joshua J. Oaks, BS, Ramasamy Santhanam, Ph.D., Roger Briesewitz, Ph.D., Danilo Perrotti, MD, Ph.D.
Journal: Blood
Blood (2007) 110 (11): 3548.
https://doi.org/10.1182/blood.V110.11.3548.3548
Published: 2007
Journal Articles

Pharmacologic inhibition of CDK4/6: mechanistic evidence for selective activity or acquired resistance in acute myeloid leukemia

Lisheng Wang, Jie Wang, Bradley W. Blaser, Anne-Marie Duchemin, Donna F. Kusewitt, Tom Liu, Michael A. Caligiuri, Roger Briesewitz
Journal: Blood
Blood (2007) 110 (6): 2075–2083.
https://doi.org/10.1182/blood-2007-02-071266
Published: 2007
Includes: Supplemental data
Journal Articles

Novel c-CBL and CBL-b ubiquitin ligase mutations in human acute myeloid leukemia

Brief Report
Michael A. Caligiuri, Roger Briesewitz, Jianhua Yu, Lisheng Wang, Min Wei, Kristy J. Arnoczky, Trent B. Marburger, Jing Wen, Danilo Perrotti, Clara D. Bloomfield, Susan P. Whitman
Journal: Blood
Blood (2007) 110 (3): 1022–1024.
https://doi.org/10.1182/blood-2006-12-061176
Published: 2007