1-20 of 396
Guido Marcucci
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Deficit of microRNA (miR)-142 Promotes Transformation of Clonal Myeloid Disorder into Acute Myeloid Leukemia (AML)

Yongfang Xu, Huafeng Wang, Fang Chen, Jihyun Irizarry, Shawn Sharkas, Dandan Zhao, Mark Boldin, Guido Marcucci, Bin Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 348.
https://doi.org/10.1182/blood-2024-211467
Published: 2024
Journal Articles

CD19-CAR T Cells As Definitive Consolidation for Older Adults with B-Cell Acute Lymphoblastic Leukemia in First Complete Remission: A Pilot Study

Ibrahim Aldoss, Xiuli Wang, Jianying Zhang, Min Guan, Ruby Espinosa, Vaibhav Agrawal, Andrew Artz, Neguine Sanani, Lior Goldberg, Teresa Kim, Stephanie Kasten, Dileshni Tilakawardane, Mary C Clark, Jamie R Wagner, Jinny Paul, Anthony S. Stein, Vinod Pullarkat, Amandeep Salhotra, Ahmed Aribi, Guido Marcucci, Stephen J. Forman
Journal: Blood
Blood (2024) 144 (Supplement 1): 966.
https://doi.org/10.1182/blood-2024-201784
Published: 2024
Journal Articles

Final Analysis of Phase 2a Study of Adding Itacitinib to Tacrolimus/Sirolimus Gvhd Prophylaxis after Fludarabine/Melphalan-Based Conditioning Hematopoietic Cell Transplantation for Acute Leukemias, Myelodysplastic Syndrome (MDS), or Myelofibrosis (MF)

Haris Ali, Dongyun Yang, NI-Chun Tsai, Sally Mokhtari, Tim W Synold, Idoroenyi Amanam, Andrew Artz, Peter T. Curtin, Karamjeet S Sandhu, Anthony S. Stein, Shukaib Arslan, Salman Otoukesh, Firoozeh Sahebi, Joshua Mansour, Paul B. Koller, Amandeep Salhotra, Ibrahim Aldoss, Vinod Pullarkat, Brian J. Ball, Stephen J. Forman, Guido Marcucci, MHD Monzr M. Al Malki, Ryotaro Nakamura
Journal: Blood
Blood (2024) 144 (Supplement 1): 1043.
https://doi.org/10.1182/blood-2024-206169
Published: 2024
Journal Articles

Disrupting Mitochondrial Dynamics and Metabolism in Leukemic Stem Cells through Mitochondrial PCNA Inhibition: The Role of AOH1996

Hyunjun Kang, Melissa Valerio, Jia Feng, Long Gu, Dinh Hoa Hoang, Shawn Sharkas, Khyatiben V. Pathak, Jennifer Jossart, Yuriy Shostak, Zhuo Li, Bin Zhang, Patrick Pirrotte, Jefferson Perry, Robert Hickey, Linda H Malkas, Guido Marcucci, Le Xuan Truong Nguyen
Journal: Blood
Blood (2024) 144 (Supplement 1): 210.
https://doi.org/10.1182/blood-2024-211269
Published: 2024
Journal Articles

TET1 Drives Myelodysplastic Syndromes and Represents a Promising Therapeutic Target

Chao Shen, Tingting Tang, Kitty Wang, Zunsong Hu, Yuan Che, Meiling Chen, Keren Zhou, Zhenhua Chen, Ying Qing, Wei Li, Dong Wu, Keith Leung, Lillian Sau, Zhaoxu Xu, Lucy Y. Ghoda, Guido Marcucci, Xiaolan Deng, Jianjun Chen
Journal: Blood
Blood (2024) 144 (Supplement 1): 3192.
https://doi.org/10.1182/blood-2024-199714
Published: 2024
Journal Articles

Targeting PRMT9 Overcomes Venetoclax Resistance in AML By Modulating Splicing and Inhibiting Translation

Yang Li, Xin He, Haojie Dong, Lei Zhang, Umesh Yadav, Meng Liu, Lianjun Zhang, Guido Marcucci, Shaoyuan Wang, Ling Li
Journal: Blood
Blood (2024) 144 (Supplement 1): 54.
https://doi.org/10.1182/blood-2024-203923
Published: 2024
Journal Articles

10 Year Follow-up of CALGB 10603/Ratify: Midostaurin Versus Placebo Plus Intensive Chemotherapy in Newly Diagnosed FLT3 Mutant Acute Myeloid Leukemia Patients Aged 18-60 Years

Richard M Stone, Jun Yin, Sumithra J Mandrekar, Axel Benner, Maral Saadati, Ilene A. Galinsky, Ben L. Sanford, Rebecca Teske, Susan M. Geyer, Thomas Prior, Sergio Amadori, Frederick R. Appelbaum, Joseph Brandwein, Konstanze Döhner, Gerhard Ehninger, Arnold Ganser, Rebecca B. Klisovic, Jürgen Krauter, Guido Marcucci, Bruno Medeiros, Dietger W. Niederwieser, Miguel A. Sanz, Richard F. Schlenk, Hubert Serve, Jorge Sierra, Martin S. Tallman, Andrew H Wei, Theo J.M. de Witte, Christian Thiede, Hartmut Döhner, Richard A. Larson
Journal: Blood
Blood (2024) 144 (Supplement 1): 218.
https://doi.org/10.1182/blood-2024-201058
Published: 2024
Journal Articles

Targeting Cytidine Triphosphate Synthase 1 Promotes Anti-AML Immunity

Meng Liu, Lei Zhang, Haojie Dong, Xin He, Yang Li, Umesh Yadav, Guido Marcucci, Ling Li
Journal: Blood
Blood (2024) 144 (Supplement 1): 3590.
https://doi.org/10.1182/blood-2024-203905
Published: 2024
Journal Articles

Phase 1b Study of IDH Inhibition with Enasidenib and MEK Inhibition with Cobimetinib in Patients with Relapsed or Refractory Acute Myeloid Leukemia Who Have Co-Occurring IDH2 and RAS Signaling Gene Mutations

Brian J. Ball, Jianying Zhang, Michelle Afkhami, Marjorie Robbins, Lauren Chang, Samantha Humpal, Vania Porras, Yilun Liu, Tim W Synold, Sarah Farzinkhou, Azra Borogovac, Paul B. Koller, Hoda Pourhassan, Vaibhav Agrawal, Anthony S. Stein, Mary-Elizabeth M. Percival, Alexey V. Danilov, Guido Marcucci
Journal: Blood
Blood (2024) 144 (Supplement 1): 6043.
https://doi.org/10.1182/blood-2024-211652
Published: 2024
Journal Articles

Mitochondrial RNA Methylation By METTL17 Rewires Metabolism and Regulates Retrograde Mitochondrial-Nuclear Communication in AML

Xueer Wang, Honghai Zhang, Lei Dong, Xiaoxu Zhang, Meilin Xue, Lili Ren, Hongjie Bi, Lucy Y. Ghoda, Mark Wunderlich, James C. Mulloy, Chun-Wei David Chen, Ling Li, Lin Xu, Bin Zhang, Guido Marcucci, Steven T. Rosen, Nora Heisterkamp, Marcin Kortylewski, Jianjun Chen, Rui Su
Journal: Blood
Blood (2024) 144 (Supplement 1): 625.
https://doi.org/10.1182/blood-2024-201916
Published: 2024
Journal Articles

BRAF -Mutated Acute Myeloid Leukemia (AML) Represents a Prognostically Poor Subgroup Enriched for Myelodysplasia-Related Subtypes and Distinct from Other RAS Pathway Mutant AML

Darren Lee, Yazan Abu-Shihab, Deedra Nicolet, Krzysztof Mrózek, Mark Routbort, Keyur P. Patel, Christopher J. Walker, Jill Buss, Andrew Stiff, Andrea Laganson, Courtney D. DiNardo, Naval Daver, Gautam Borthakur, Tapan M. Kadia, Farhad Ravandi, Andrew J. Carroll, Jonathan E Kolitz, Bayard L Powell, William Blum, Maria R. Baer, Guido Marcucci, Geoffrey L. Uy, Wendy Stock, Richard M. Stone, L. Jeffrey Medeiros, Jeffrey W. Tyner, Robert L. Bowman, John C. Byrd, James S. Blachly, Sanam Loghavi, Ann-Kathrin Eisfeld, Linde A. Miles
Journal: Blood
Blood (2024) 144 (Supplement 1): 2921.
https://doi.org/10.1182/blood-2024-210110
Published: 2024
Journal Articles

High HDAC8 Creates Targetable Vulnerabilities in Acute Myeloid Leukemia through Dysregulation of BRCA1-Related RNA Splicing Machinery and Defective DNA Damage Repair

Lianjun Zhang, Yu-Hsuan Fu, Wei-Kai Hua, Le Xuan Truong Nguyen, Xin He, Wancheng Guo, Yinghui Zhu, Ying-Chieh Chen, Zhenhua Chen, Haojie Dong, Lei Zhang, Bin Zhang, Jeremy Stark, Ling Li, Guido Marcucci, Ya-Huei Kuo
Journal: Blood
Blood (2024) 144 (Supplement 1): 1398.
https://doi.org/10.1182/blood-2024-208137
Published: 2024
Journal Articles

TP53 Mutations Increased the Risk of CD19 Negative Relapse Following Blinatumomab in Adults with B-Cell Acute Lymphoblastic Leukemia (B-ALL)

Ibrahim Aldoss, Jeffrey Li, Jianying Zhang, Mary C Clark, Vaibhav Agrawal, Hoda Pourhassan, Paul B. Koller, Ahmed Aribi, Haris Ali, Amanda Blackmon, Salman Otoukesh, Karamjeet S Sandhu, Brian J. Ball, Andrew Artz, Idoroenyi Amanam, MHD Monzr M. Al Malki, Amandeep Salhotra, Lindsey A. Murphy, Dat Ngo, Jose Tinajero, Zhaohui Gu, Pamela S. Becker, Ryotaro Nakamura, Anthony S. Stein, Guido Marcucci, Stephen J. Forman, Vinod Pullarkat
Journal: Blood
Blood (2024) 144 (Supplement 1): 729.
https://doi.org/10.1182/blood-2024-208674
Published: 2024
Journal Articles

Combined CXCR-4 Inhibition with Novel Agent GPC-100 (burixafor) and Beta 2 Adrenergic Receptor Blockade Enhances Cytarabine Response for Acute Myeloid Leukemia Blasts on Stroma

Yueming Tang, Adam Braun, Zachary von Behren, Jieya Wu, Caitlyn Haley, Chunxiao Zhang, Brenda Loera, Pina M. Cardarelli, Nina Caculitan, Sylvia Chien, Jin Dai, Vivian G. Oehler, Jianying Zhang, Guido Marcucci, Pamela S. Becker
Journal: Blood
Blood (2024) 144 (Supplement 1): 2758.
https://doi.org/10.1182/blood-2024-210120
Published: 2024
Journal Articles

Acquired microRNA (miR)-142 Deficit Drives Immune Escape in Acute Myeloid Leukemia (AML)

Fang Chen, Dandan Zhao, Yongfang Xu, Huafeng Wang, Shawn Sharkas, Le Xuan Truong Nguyen, Lucy Y. Ghoda, Mark Boldin, Guido Marcucci, Bin Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 2944.
https://doi.org/10.1182/blood-2024-210855
Published: 2024
Journal Articles

Phase 1 Trial of Navitoclax/Venetoclax/Decitabine Combination in Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML)

Anthony S. Stein, Jianying Zhang, Lucy Y. Ghoda, Marjorie Robbins, Cindy Croslin, Banafsheh Sinaki, Ahmed Aribi, Amanda Blackmon, Hoda Pourhassan, Brian J. Ball, Ibrahim Aldoss, Ryotaro Nakamura, MHD Monzr M. Al Malki, Karamjeet S Sandhu, Guido Marcucci
Journal: Blood
Blood (2024) 144 (Supplement 1): 4264.
https://doi.org/10.1182/blood-2024-205980
Published: 2024
Journal Articles

Outcomes of Hypomethylating Agents/Venetoclax (HMA/VEN) Treatment for Relapse of Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) after Allogeneic Hematopoietic Cell Transplant (alloHCT)

Diana T Samuels, Brian J. Ball, NI-Chun Tsai, Amanda Blackmon, Vaibhav Agrawal, Hoda Pourhassan, Idoroenyi Amanam, Paul B. Koller, Shukaib Arslan, Salman Otoukesh, Karamjeet S Sandhu, Ibrahim Aldoss, Haris Ali, Amandeep Salhotra, MHD Monzr M. Al Malki, Andrew Artz, Pamela S. Becker, Ahmed Aribi, Eileen Patricia Smith, Stephen J. Forman, Anthony S. Stein, Guido Marcucci, Ryotaro Nakamura, Vinod Pullarkat
Journal: Blood
Blood (2024) 144 (Supplement 1): 4935.
https://doi.org/10.1182/blood-2024-210956
Published: 2024
Journal Articles

Homoharringtonine inhibits the NOTCH/MYC pathway and exhibits antitumor effects in T-cell acute lymphoblastic leukemia

Shanshan Suo, Dandan Zhao, Fenglin Li, Yi Zhang, Sonia Rodriguez-Rodriguez, Le Xuan Truong Nguyen, Lucy Ghoda, Nadia Carlesso, Guido Marcucci, Bin Zhang, Jie Jin
Journal: Blood
Blood (2024) 144 (12): 1343–1347.
https://doi.org/10.1182/blood.2023023400
Published: 2024
Includes: Supplemental data
Journal Articles

Glofitamab stimulates immune cell infiltration of CNS tumors and induces clinical responses in secondary CNS lymphoma

James K. Godfrey, Lei Gao, Geoffrey Shouse, Joo Y. Song, Stacy Pak, Brian Lee, Bihong T. Chen, Avyakta Kallam, John H. Baird, Guido Marcucci, Lucy Ghoda, Stephanie Vauleon, Alexey V. Danilov, Alex F. Herrera, Larry W. Kwak, Lihua E. Budde
Journal: Blood
Blood (2024) 144 (4): 457–461.
https://doi.org/10.1182/blood.2024024168
Published: 2024
Includes: Supplemental data
Journal Articles

A CD38-directed, single-chain T-cell engager targets leukemia stem cells through IFN-γ–induced CD38 expression

Mariam Murtadha, Miso Park, Yinghui Zhu, Enrico Caserta, Ottavio Napolitano, Theophilus Tandoh, Milad Moloudizargari, Alex Pozhitkov, Mahmoud Singer, Ada Alice Dona, Hawa Vahed, Asaul Gonzalez, Kevin Ly, Ching Ouyang, James F. Sanchez, Lokesh Nigam, Amanda Duplan, Arnab Chowdhury, Lucy Ghoda, Ling Li, Bin Zhang, Amrita Krishnan, Guido Marcucci, John C. Williams, Flavia Pichiorri
Journal: Blood
Blood (2024) 143 (16): 1599–1615.
https://doi.org/10.1182/blood.2023021570
Published: 2024
Includes: Supplemental data