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Journal Articles

CD19-CAR T Cells As Definitive Consolidation for Older Adults with B-Cell Acute Lymphoblastic Leukemia in First Complete Remission: A Pilot Study

Ibrahim Aldoss, Xiuli Wang, Jianying Zhang, Min Guan, Ruby Espinosa, Vaibhav Agrawal, Andrew Artz, Neguine Sanani, Lior Goldberg, Teresa Kim, Stephanie Kasten, Dileshni Tilakawardane, Mary C Clark, Jamie R Wagner, Jinny Paul, Anthony S. Stein, Vinod Pullarkat, Amandeep Salhotra, Ahmed Aribi, Guido Marcucci, Stephen J. Forman
Journal: Blood
Blood (2024) 144 (Supplement 1): 966.
https://doi.org/10.1182/blood-2024-201784
Published: 2024
Journal Articles

Phase 1b Study of IDH Inhibition with Enasidenib and MEK Inhibition with Cobimetinib in Patients with Relapsed or Refractory Acute Myeloid Leukemia Who Have Co-Occurring IDH2 and RAS Signaling Gene Mutations

Brian J. Ball, Jianying Zhang, Michelle Afkhami, Marjorie Robbins, Lauren Chang, Samantha Humpal, Vania Porras, Yilun Liu, Tim W Synold, Sarah Farzinkhou, Azra Borogovac, Paul B. Koller, Hoda Pourhassan, Vaibhav Agrawal, Anthony S. Stein, Mary-Elizabeth M. Percival, Alexey V. Danilov, Guido Marcucci
Journal: Blood
Blood (2024) 144 (Supplement 1): 6043.
https://doi.org/10.1182/blood-2024-211652
Published: 2024
Journal Articles

TP53 Mutations Increased the Risk of CD19 Negative Relapse Following Blinatumomab in Adults with B-Cell Acute Lymphoblastic Leukemia (B-ALL)

Ibrahim Aldoss, Jeffrey Li, Jianying Zhang, Mary C Clark, Vaibhav Agrawal, Hoda Pourhassan, Paul B. Koller, Ahmed Aribi, Haris Ali, Amanda Blackmon, Salman Otoukesh, Karamjeet S Sandhu, Brian J. Ball, Andrew Artz, Idoroenyi Amanam, MHD Monzr M. Al Malki, Amandeep Salhotra, Lindsey A. Murphy, Dat Ngo, Jose Tinajero, Zhaohui Gu, Pamela S. Becker, Ryotaro Nakamura, Anthony S. Stein, Guido Marcucci, Stephen J. Forman, Vinod Pullarkat
Journal: Blood
Blood (2024) 144 (Supplement 1): 729.
https://doi.org/10.1182/blood-2024-208674
Published: 2024
Journal Articles

Combined CXCR-4 Inhibition with Novel Agent GPC-100 (burixafor) and Beta 2 Adrenergic Receptor Blockade Enhances Cytarabine Response for Acute Myeloid Leukemia Blasts on Stroma

Yueming Tang, Adam Braun, Zachary von Behren, Jieya Wu, Caitlyn Haley, Chunxiao Zhang, Brenda Loera, Pina M. Cardarelli, Nina Caculitan, Sylvia Chien, Jin Dai, Vivian G. Oehler, Jianying Zhang, Guido Marcucci, Pamela S. Becker
Journal: Blood
Blood (2024) 144 (Supplement 1): 2758.
https://doi.org/10.1182/blood-2024-210120
Published: 2024
Journal Articles

Phase 1 Trial of Navitoclax/Venetoclax/Decitabine Combination in Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML)

Anthony S. Stein, Jianying Zhang, Lucy Y. Ghoda, Marjorie Robbins, Cindy Croslin, Banafsheh Sinaki, Ahmed Aribi, Amanda Blackmon, Hoda Pourhassan, Brian J. Ball, Ibrahim Aldoss, Ryotaro Nakamura, MHD Monzr M. Al Malki, Karamjeet S Sandhu, Guido Marcucci
Journal: Blood
Blood (2024) 144 (Supplement 1): 4264.
https://doi.org/10.1182/blood-2024-205980
Published: 2024
Journal Articles

Single Center Retrospective Study of Midostaurin Plus Intensive Chemotherapy for Older Patients with Newly Diagnosed FLT-3 Mutated Acute Myelogenous Leukemia

Jose Tinajero, Dat Ngo, Jianying Zhang, NI-Chun Tsai, Joycelynne Michelle Palmer, Ahmed Aribi, Ibrahim Aldoss, Vaibhav Agrawal, Shukaib Arslan, Idoroenyi Amanam, Hoda Pourhassan, Karamjeet S. Sandhu, Monzr M. Al Malki, Vinod Pullarkat, Pamela S. Becker, Ryotaro Nakamura, Anthony Stein, Guido Marcucci, Andrew Artz, Paul B. Koller, Amandeep Salhotra
Journal: Blood
Blood (2023) 142 (Supplement 1): 5937.
https://doi.org/10.1182/blood-2023-173978
Published: 2023
Journal Articles

Concurrent Versus Sequential or No Triazole Anti-Fungal Therapy in Patients Undergoing 7+3 Plus Midostaurin Induction for FLT-3 Acute Myelogenous Leukemia

Dat Ngo, Jose Tinajero, Jianying Zhang, Anthony Stein, Guido Marcucci, Amandeep Salhotra, Vinod Pullarkat, Karamjeet S. Sandhu, Brian J. Ball, Paul B. Koller
Journal: Blood
Blood (2023) 142 (Supplement 1): 5932.
https://doi.org/10.1182/blood-2023-173973
Published: 2023
Journal Articles

Transfer of mRNA Encoding CEBPA in Lipid Nanoparticles to CEBPA Mutated Leukemia Cell Line KO52 and Primary AML Reduces Cell Growth and Induces Myeloid Differentiation

Chunxiao Zhang, Brenda Loera, Jianying Zhang, Richard Gelinas, Youmna Kfoury, Jonathan Hoggatt, Guido Marcucci, Pamela S. Becker
Journal: Blood
Blood (2023) 142 (Supplement 1): 7122.
https://doi.org/10.1182/blood-2023-190191
Published: 2023
Journal Articles

A Phase 1 Study of Venetoclax in Combination with a Pediatric-Inspired Regimen for the Treatment of Newly Diagnosed Adults with B-Cell Ph-like ALL

Ibrahim Aldoss, Jianying Zhang, Marjorie Robbins, Vaibhav Agrawal, Ahmed Aribi, Hoda Pourhassan, Paul B. Koller, Amanda Blackmon, Karamjeet S. Sandhu, Haris Ali, Brian J. Ball, Andrew Artz, Monzr M. Al Malki, Amandeep Salhotra, Zhaohui Gu, Asucena Leon Beltran, Christina Lai, Michelle Afkhami, Lucy Y. Ghoda, Stephen J. Forman, Guido Marcucci, Anthony Stein, Vinod Pullarkat
Journal: Blood
Blood (2023) 142 (Supplement 1): 2870.
https://doi.org/10.1182/blood-2023-187469
Published: 2023
Journal Articles

Human ILC1s Target Leukemia Stem Cells and Control Development of AML

Zhenlong Li, Hejun Tang, Victoria Chen, Rui Ma, Jianying Zhang, Guido Marcucci, Jianhua Yu, Michael A Caligiuri
Journal: Blood
Blood (2023) 142 (Supplement 1): 886.
https://doi.org/10.1182/blood-2023-190767
Published: 2023
Journal Articles

The NK Cell Receptor NKp46 Acts As an Essential Regulator of ILC1 Proliferation, Effector Function and Anti-AML Activity

Rui Ma, Zhenlong Li, Hejun Tang, Lei Tian, Zahir Shah, Tasha Barr, Amy Peng, Jianying Zhang, Srividya Swaminathan, Michael A Caligiuri, Jianhua Yu
Journal: Blood
Blood (2023) 142 (Supplement 1): 3925.
https://doi.org/10.1182/blood-2023-191070
Published: 2023
Journal Articles

Interim Results of a Phase 1/2 Study of Pembrolizumab Combined with Blinatumomab in Patients with Relapsed/Refractory (r/r) ALL

Karamjeet S. Sandhu, Alan Macias, Marissa Del Real, Asuscena L. Beltran, Young Sun Kim, Jianying Zhang, Joycelynne Palmer, Marjorie Robbins, Reyna Loomis, Mojtaba Akhtari, Ahmed Aribi, Shukaib Arslan, Amandeep Salhotra, Matthew Mei, Hoda Pourhassan, Paul B. Koller, Idoroenyi Amanam, Vaibhav Agrawal, Peter T. Curtin, Ricardo Spielberger, Vinod A. Pullarkat, Ibrahim Aldoss, F. Mark Stewart, Eileen P. Smith, Stephen J Forman, Anthony S. Stein, Guido Marcucci, L. Elizabeth Budde
Journal: Blood
Blood (2022) 140 (Supplement 1): 8985–8986.
https://doi.org/10.1182/blood-2022-170279
Published: 2022
Journal Articles

Evaluation of 5-Day Vs. 10-Day Decitabine in Combination with Venetoclax in Newly Diagnosed AML Patients Ineligible for Induction Chemotherapy

Jorge M. Ramos Perez, Jose Tinajero, Dat Ngo, Jianying Zhang, Paul B. Koller, Vaibhav Agrawal, Hoda Pourhassan, Monzr M. Al Malki, Amandeep Salhotra, Haris Ali, Ahmed Aribi, Karamjeet S. Sandhu, Shukaib Arslan, Salman Otoukesh, Idoroenyi Amanam, Andrew S. Artz, Pamela S. Becker, Forrest M. Stewart, Eileen P. Smith, Peter Curtin, Stephen J Forman, Ryotaro Nakamura, Vinod A. Pullarkat, Guido Marcucci, Anthony S. Stein, Ibrahim Aldoss, Brian J Ball
Journal: Blood
Blood (2022) 140 (Supplement 1): 9039–9040.
https://doi.org/10.1182/blood-2022-170867
Published: 2022
Journal Articles

Targeting Leukemic Stem Cells in Acute Myeloid Leukemia Using a CpG-Linked Anti-Mir-126 Oligonucleotide

Lucy Y Ghoda, Ebtesam Nafie, Elizabeth Bloom-Saldana, Patrick T. Fueger, Timothy Synold, James Simpson, Piotr Swiderski, Kokilah Muthaiyah, Bin Zhang, Marcin Kortylewski, Steven Vonderfecht, Le Xuan Truong Nguyen, Jianying Zhang, Joycelynne Palmer, Guido Marcucci
Journal: Blood
Blood (2022) 140 (Supplement 1): 10673–10674.
https://doi.org/10.1182/blood-2022-171147
Published: 2022
Journal Articles

A Phase 1b Study of IDH Inhibition with Enasidenib and MEK Inhibition with Cobimetinib in Patients with Relapsed or Refractory Acute Myeloid Leukemia Who Have Co-Occurring IDH2 and RAS Signaling Gene Mutations

Brian J Ball, Eytan Stein, Marjorie Robbins, Jianying Zhang, Ross L. Levine, Timothy Synold, Anthony S. Stein, Guido Marcucci, Yilun Liu, Alexey V Danilov
Journal: Blood
Blood (2022) 140 (Supplement 1): 11761–11762.
https://doi.org/10.1182/blood-2022-170820
Published: 2022
Journal Articles

Promising Safety and Efficacy Results from an Ongoing Phase 1b Study of Pembrolizumab Combined with Decitabine in Patients with Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML)

Vaibhav Agrawal, Cindy Croslin, Asuscena L. Beltran, Jianying Zhang, Joycelynne Palmer, Quy Huynh-Tran, Rochelle Hernandez, Sandra Thomas, Marjorie Robbins, Ahmed Aribi, Haris Ali, Anthony S. Stein, Elizabeth L. Budde, Monzr M. Al Malki, Guido Marcucci
Journal: Blood
Blood (2022) 140 (Supplement 1): 6235–6236.
https://doi.org/10.1182/blood-2022-165894
Published: 2022
Journal Articles

Clinical Outcomes of Patients with Secondary Acute Myeloid Leukemia (sAML) Treated with Hypomethylating Agent Plus Venetoclax (HMA-Ven) or Liposomal Daunorubicin Cytarabine (CPX-351)

Amandeep Salhotra, MD, Dat Ngo, PharmD, Jianying Zhang, Karamjeet S. Sandhu, MD, Monzr M. Al Malki, MD, Ahmed Aribi, MD, Haris Ali, MD, Pkoller Koller, MD, Shukaib Arslan, MD, Andrew S. Artz, MD, Lihua E Budde, MD PhD, Samer Khaled, MD, Sanjeet S Dadwal, MD, David S Snyder, MD, Stephen J. Forman, MD, Ryotaro Nakamura, MD, Anthony S. Stein, MD, Guido Marcucci, MD, Ibrahim Aldoss, MD, Vinod A. Pullarkat, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 37–38.
https://doi.org/10.1182/blood-2020-140538
Published: 2020
Journal Articles

Outcomes of Therapy with Venetoclax Combined with Hypomethylating Agents in Favorable-Risk Acute Myeloid Leukemia (AML)

Shukaib Arslan, MD, Jianying Zhang, Prajwal Dhakal, MBBS, Jenna A. Moran, NP, Nuthana Naidoo, Jennifer Lombardi Story, Vinod A. Pullarkat, MD, Anthony S. Stein, MD, Guido Marcucci, MD, George Yaghmour, MD, Vijaya R. Bhatt, MD, Amir T. Fathi, Ibrahim Aldoss, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 41–42.
https://doi.org/10.1182/blood-2020-142780
Published: 2020
Journal Articles

Incidence and Causes of Prolonged Hematologic Toxicity after Chimeric Antigen Receptor T Cell Therapy: A City of Hope (COH) Experience

Geoffrey Shouse, DO, PhD, Thai Cao, MD, Jianying Zhang, Matthew Mei, MD, Alex F. Herrera, MD, Liana Nikolaenko, MD, Jasmine Zain, MD, Tanya Siddiqi, MD, Leslie L. Popplewell, MD FACP, Stephen J. Forman, MD, Lihua E Budde, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 40–41.
https://doi.org/10.1182/blood-2020-143353
Published: 2020
Journal Articles

Enhancement of Natural Killer Cell Interferon-Gamma Production By the Derivatives of the Natural Product Phyllanthusmins Via TLR-Mediated NF-Kb and STAT3 Signaling Pathways

Luxi Chen, Long Yi, Yuning Ren, Jianying Zhang, A. Douglas Kinghorn, Michael A. Caligiuri, MD, Jianhua Yu, PhD
Journal: Blood
Blood (2015) 126 (23): 1031.
https://doi.org/10.1182/blood.V126.23.1031.1031
Published: 2015