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Lucy Y Ghoda
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Journal Articles

Mitochondrial RNA Methylation By METTL17 Rewires Metabolism and Regulates Retrograde Mitochondrial-Nuclear Communication in AML

Xueer Wang, Honghai Zhang, Lei Dong, Xiaoxu Zhang, Meilin Xue, Lili Ren, Hongjie Bi, Lucy Y. Ghoda, Mark Wunderlich, James C. Mulloy, Chun-Wei David Chen, Ling Li, Lin Xu, Bin Zhang, Guido Marcucci, Steven T. Rosen, Nora Heisterkamp, Marcin Kortylewski, Jianjun Chen, Rui Su
Journal: Blood
Blood (2024) 144 (Supplement 1): 625.
https://doi.org/10.1182/blood-2024-201916
Published: 2024
Journal Articles

Acquired microRNA (miR)-142 Deficit Drives Immune Escape in Acute Myeloid Leukemia (AML)

Fang Chen, Dandan Zhao, Yongfang Xu, Huafeng Wang, Shawn Sharkas, Le Xuan Truong Nguyen, Lucy Y. Ghoda, Mark Boldin, Guido Marcucci, Bin Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 2944.
https://doi.org/10.1182/blood-2024-210855
Published: 2024
Journal Articles

Phase 1 Trial of Navitoclax/Venetoclax/Decitabine Combination in Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML)

Anthony S. Stein, Jianying Zhang, Lucy Y. Ghoda, Marjorie Robbins, Cindy Croslin, Banafsheh Sinaki, Ahmed Aribi, Amanda Blackmon, Hoda Pourhassan, Brian J. Ball, Ibrahim Aldoss, Ryotaro Nakamura, MHD Monzr M. Al Malki, Karamjeet S Sandhu, Guido Marcucci
Journal: Blood
Blood (2024) 144 (Supplement 1): 4264.
https://doi.org/10.1182/blood-2024-205980
Published: 2024
Journal Articles

TET1 Drives Myelodysplastic Syndromes and Represents a Promising Therapeutic Target

Chao Shen, Tingting Tang, Kitty Wang, Zunsong Hu, Yuan Che, Meiling Chen, Keren Zhou, Zhenhua Chen, Ying Qing, Wei Li, Dong Wu, Keith Leung, Lillian Sau, Zhaoxu Xu, Lucy Y. Ghoda, Guido Marcucci, Xiaolan Deng, Jianjun Chen
Journal: Blood
Blood (2024) 144 (Supplement 1): 3192.
https://doi.org/10.1182/blood-2024-199714
Published: 2024
Journal Articles

CD38-Directed, Single-Chain T Cell-Engager Targets Leukemia Stem Cells through IFNγ-Induced CD38 Expression

Mariam Murtadha, Miso Park, Yinghui Zhu, Enrico Caserta, Ottavio Napolitano, Theophilus Tandoh, Milad Moloudizargari, Alexander Pozhitkov, Mahmoud Singer, Ada Alice Dona, Hawa Vahed, Asaul Gonzalez, Kevin Ly, Ching Ouyang, James Sanchez, Lokesh Nigam, Arnab Chowdhury, Lucy Y. Ghoda, Ling Li, Bin Zhang, Amrita Krishnan, Guido Marcucci, John C. Williams, Flavia Pichiorri
Journal: Blood
Blood (2023) 142 (Supplement 1): 2797.
https://doi.org/10.1182/blood-2023-189901
Published: 2023
Journal Articles

A Phase 1 Study of Venetoclax in Combination with a Pediatric-Inspired Regimen for the Treatment of Newly Diagnosed Adults with B-Cell Ph-like ALL

Ibrahim Aldoss, Jianying Zhang, Marjorie Robbins, Vaibhav Agrawal, Ahmed Aribi, Hoda Pourhassan, Paul B. Koller, Amanda Blackmon, Karamjeet S. Sandhu, Haris Ali, Brian J. Ball, Andrew Artz, Monzr M. Al Malki, Amandeep Salhotra, Zhaohui Gu, Asucena Leon Beltran, Christina Lai, Michelle Afkhami, Lucy Y. Ghoda, Stephen J. Forman, Guido Marcucci, Anthony Stein, Vinod Pullarkat
Journal: Blood
Blood (2023) 142 (Supplement 1): 2870.
https://doi.org/10.1182/blood-2023-187469
Published: 2023
Journal Articles

Acquired microRNA-142 Deficit Drives Escape Mechanisms of Anti-Leukemic Surveillance during Blast Crisis Transformation of Chronic Myeloid Leukemia (CML)

Fang Chen, Dandan Zhao, Yi Zhang, Yongfang Xu, Min-Hsuan Chen, Khyatiben V. Pathak, Yong Liang, Wei-Le Wang, Katrina Estrella, Xiwei Wu, Lucy Y. Ghoda, Ya-Huei Kuo, Haris Ali, Jianhua Yu, Michael A Caligiuri, Mark Boldin, Piotr Swiderski, Marcin Kortylewski, Patrick Pirrotte, Le Xuan Truong Nguyen, Guido Marcucci, Bin Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 3152.
https://doi.org/10.1182/blood-2023-182587
Published: 2023
Journal Articles

Synergistic Activity of Adefovir Dipivoxil and Venetoclax to Target the Bioenergetic Metabolism of Acute Myeloid Leukemia

Xubo Gong, Yi Zhang, Ying-Chieh Chen, Dandan Zhao, Yongfang Xu, Xin He, Fang Chen, Lei Zhang, Lianjun Zhang, Katrina Estrella, Melissa Valerio, Lucy Y. Ghoda, Le Xuan Truong Nguyen, Ya-Huei Kuo, Weiwei Liu, Zhihua Tao, Guido Marcucci, Bin Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 4161.
https://doi.org/10.1182/blood-2023-187183
Published: 2023
Journal Articles

Herpesvirus Entry Mediator As a Novel Therapeutic Target in Multiple Myeloma

Milad Moloudizargari, Ada Alice Dona, Miso Park, Theophilus Tandoh, Mariam Murtadha, Enrico Caserta, Alexander Pozhitkov, Yinghui Zhu, Ottavio Napolitano, James Sanchez, Lokesh Nigam, Amanda Duplan, Arnab Chowdhury, Lucy Y. Ghoda, Jonathan Keats, Scott R. Goldsmith, Michael Rosenzweig, Amrita Krishnan, John C. Williams, Flavia Pichiorri
Journal: Blood
Blood (2023) 142 (Supplement 1): 3296.
https://doi.org/10.1182/blood-2023-190157
Published: 2023
Journal Articles

IL1RAP-Specific T Cell Engager (TCE) Antibody Efficiently Depletes Acute Myeloid Leukemia (AML) Leukemic Stem Cells (LSCs)

Yi Zhang, Miso Park, Bin Zhang, Lucy Y. Ghoda, Dandan Zhao, Melissa Valerio, Ebtesam Nafie, Xubo Gong, Fang Chen, Yongfang Xu, Katrina Estrella, Kaito Harada, Shawn Sharkas, Hyunjun Kang, Dinh Hoa Hoang, Le Xuan Truong Nguyen, Stephen J. Forman, Idoroenyi Amanam, Flavia Pichiorri, Jie Jin, John C. Williams, Guido Marcucci
Journal: Blood
Blood (2023) 142 (Supplement 1): 586.
https://doi.org/10.1182/blood-2023-185405
Published: 2023
Journal Articles

Targeting Leukemic Stem Cells in Acute Myeloid Leukemia Using a CpG-Linked Anti-Mir-126 Oligonucleotide

Lucy Y Ghoda, Ebtesam Nafie, Elizabeth Bloom-Saldana, Patrick T. Fueger, Timothy Synold, James Simpson, Piotr Swiderski, Kokilah Muthaiyah, Bin Zhang, Marcin Kortylewski, Steven Vonderfecht, Le Xuan Truong Nguyen, Jianying Zhang, Joycelynne Palmer, Guido Marcucci
Journal: Blood
Blood (2022) 140 (Supplement 1): 10673–10674.
https://doi.org/10.1182/blood-2022-171147
Published: 2022
Journal Articles

Phase 1/2 Study of Nexi-001 Donor-Derived Multi-Antigen Specific CD8+ T Cells for the Treatment of Relapsed Acute Myeloid Leukemia (AML) after Allogeneic Hematopoietic Transplantation

Monzr M. Al Malki, Sumithira Vasu, Dipenkumar Modi, Miguel-Angel Perales, Lucy Y Ghoda, Donna Bui, Vineetha Edavana, Emily Lu, Sojung Kim, Lauren Suarez, Mathias Oelke, Daniel Bednarik, Robert D Knight, Juan C. Varela
Journal: Blood
Blood (2021) 138 (Supplement 1): 4819.
https://doi.org/10.1182/blood-2021-152419
Published: 2021
Journal Articles

Multi-Antigen Primed T Cells Promote Apoptosis of Acute Myeloid Leukemia (AML)

Ebtesam Nafie, Mathias Oelke, Melissa Valerio, Sojung Kim, Ivan Rodriguez, Benjamin Peton, Ketevan Gendzekhadze, Michiko Taniguchi, Guido Marcucci, Monzr M. Al Malki, Lucy Y Ghoda
Journal: Blood
Blood (2021) 138 (Supplement 1): 4794.
https://doi.org/10.1182/blood-2021-152084
Published: 2021
Journal Articles

A Randomized Open Label Pilot Study of Clostridium Butyricum Miyairi 588 (CBM588) in Recipients of Allogeneic Hematopoietic Cell Transplantation

Karamjeet S. Sandhu, Dongyun Yang, Sally Mokhtari, Sanjeet S Dadwal, Vinod A. Pullarkat, Monzr M. Al Malki, Thai Cao, Ricardo Spielberger, Amandeep Salhotra, Haris Ali, Andrew S. Artz, Anthony S. Stein, Myo Htut, Elizabeth Budde, Leslie L. Popplewell, Harry Xu, Lauren Reining, Lucy Y Ghoda, Ibrahim Aldoss, Guido Marcucci, Stephen J Forman, Sarah Highlander, Ryotaro Nakamura
Journal: Blood
Blood (2021) 138 (Supplement 1): 334.
https://doi.org/10.1182/blood-2021-153821
Published: 2021