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Journal Articles

Multidimensional Analysis of Relapsed Bone Marrow Reveals Cold Immune Microenvironment Post-TMLI in Acute Leukemia Transplant Patients

Srideshikan Sargur Madabushi, Ji Eun Lim, Yu-Lin SU, Paresh Vishwasrao, Dongyun Yang, James F. Sanchez, Sally Mokhtari, Amandeep Salhotra, Xiwei Wu, Haiqing Lee, Savita Dandapani, Ryotaro Nakamura, Raju Pillai, Marcin Kortylewski, Jeffrey Wong, MHD Monzr M. Al Malki, Anthony S. Stein, Susanta Hui
Journal: Blood
Blood (2024) 144 (Supplement 1): 775.
https://doi.org/10.1182/blood-2024-211180
Published: 2024
Journal Articles

Randomized Phase 2 Trial of the Anti-PD-L1 Monoclonal Antibody Durvalumab Plus Lenalidomide Versus Single-Agent Durvalumab in Patients with Refractory/Advanced Cutaneous T Cell Lymphoma

Christiane Querfeld, Lu Chen, Xiwei Wu, Zhen Han, ChingYu Su, Melissa Banez, Jeralyn Quach, Tiffanie Barnhizer, Liliana Crisan, Steven T. Rosen, Jasmine Zain
Journal: Blood
Blood (2024) 144 (Supplement 1): 468.
https://doi.org/10.1182/blood-2024-205617
Published: 2024
Journal Articles

Donor T-Derived Memory Progenitors Differentiated into CD103 +/- CXCR6 + CD4 + Tissue-Resident T Cell Subsets Driven Cutaneous Chronic Graft-Versus-Host Disease

Xiaohui Kong, Bixin Wang, Xiwei Wu, Weijia Fu, Qinjian Li, Moqian Zheng, Raju Pillai, Ryotaro Nakamura, Paul J. Martin, Defu Zeng
Journal: Blood
Blood (2024) 144 (Supplement 1): 4776.
https://doi.org/10.1182/blood-2024-210519
Published: 2024
Journal Articles

Preliminary Analysis Demonstrates Durvalumab (Anti-PD-L1) & Lenalidomide Is Superior to Single-Agent Durvalumab (anti-PD-L1) in Refractory/Advanced Cutaneous T Cell Lymphoma in a Randomized Phase 2 Trial

Christiane Querfeld, Lu Chen, Xiwei Wu, Zhen Han, ChingYu Su, Melissa Banez, Jeralyn Quach, Tiffanie Barnhizer, Liliana Crisan, Steven T. Rosen, Jasmine M. Zain
Journal: Blood
Blood (2023) 142 (Supplement 1): 3077.
https://doi.org/10.1182/blood-2023-188053
Published: 2023
Journal Articles

Clonal Expansion and Differentiation of Stem-like Memory T Cells to Tissue-Resident Memory T Cells Perpetuates Pathogenesis of Chronic Graft-Versus-Host Disease

Xiaohui Kong, Bixin Wang, Xiwei Wu, Hyejin Cho, Moqian Zheng, Yuankun Zhang, Shanshan Tang, Qinjian Li, Ubaydah Nasri, Alyssa Wu, Hanjun Qin, Raju Pillai, Ryotaro Nakamura, Paul J. Martin, Yuanzhong Chen, Defu Zeng
Journal: Blood
Blood (2023) 142 (Supplement 1): 2044.
https://doi.org/10.1182/blood-2023-174768
Published: 2023
Journal Articles

Acquired microRNA-142 Deficit Drives Escape Mechanisms of Anti-Leukemic Surveillance during Blast Crisis Transformation of Chronic Myeloid Leukemia (CML)

Fang Chen, Dandan Zhao, Yi Zhang, Yongfang Xu, Min-Hsuan Chen, Khyatiben V. Pathak, Yong Liang, Wei-Le Wang, Katrina Estrella, Xiwei Wu, Lucy Y. Ghoda, Ya-Huei Kuo, Haris Ali, Jianhua Yu, Michael A Caligiuri, Mark Boldin, Piotr Swiderski, Marcin Kortylewski, Patrick Pirrotte, Le Xuan Truong Nguyen, Guido Marcucci, Bin Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 3152.
https://doi.org/10.1182/blood-2023-182587
Published: 2023
Journal Articles

Trafficking between clonally related peripheral T-helper cells and tissue-resident T-helper cells in chronic GVHD

Xiaohui Kong, Xiwei Wu, Bixin Wang, Deye Zeng, Kaniel Cassady, Ubaydah Nasri, Moqian Zheng, Alyssa Wu, Hanjun Qin, Weimin Tsai, Amandeep Salhotra, Ryotaro Nakamura, Paul J. Martin, Defu Zeng
Journal: Blood
Blood (2022) 140 (25): 2740–2753.
https://doi.org/10.1182/blood.2022016581
Published: 2022
Includes: Supplemental data
Journal Articles

Receptor Targeted Delivery of the p38γ Inhibitor PIK-75 By Organic-Core Templated Lipid Nanoparticles in Cutaneous T Cell Lymphoma

Jonathan Scott Rink, Stephen E. Henrich, Alexandra Moxley, Xu Hannah Zhang, Xiwei Wu, SonBinh Nguyen, Christiane Querfeld, David A. Horne, Steve T. Rosen, Leo I. Gordon, Colby Shad Thaxton, Adam Yuh Lin
Journal: Blood
Blood (2022) 140 (Supplement 1): 4934–4935.
https://doi.org/10.1182/blood-2022-158864
Published: 2022
Journal Articles

Targeting PRMT9 Elicits Cgas-Mediated Anti-Leukemia Immunity

Haojie Dong, Xin He, Lei Zhang, Wei Chen, Yichun Lin, Songbai Liu, Huafeng Wang, Wenfeng Huang, Sierra Min Li, Yinghui Zhu, Dandan Zhao, Lucy Ghoda, Rui Su, Jianjun Chen, Ritin Sharma, Patrick Pirrotte, Xiwei Wu, Weidong Hu, Weidong Han, Binghui Shen, Ya-Huei Kuo, Jie Jin, Amandeep Salhotra, Jeffrey Wang, Guido Marcucci, Yun Luo, Ling Li
Journal: Blood
Blood (2022) 140 (Supplement 1): 4931–4933.
https://doi.org/10.1182/blood-2022-167366
Published: 2022
Journal Articles

Targeting Intestinal Epithelial Ceacam1 Expands Peripheral Tregs and Prevents Steroid-Refractory Acute Gut Graft-Versus-Host Disease

Qingxiao Song, Moqian Zheng, Qinjian Li, Xiwei Wu, Hanjun Qin, Tae Hyuk Kang, Yaqun Hong, Bixin Wang, Maciej Kujawski, Jack Shively, Ryotaro Nakamura, Paul J Martin, Defu Zeng
Journal: Blood
Blood (2022) 140 (Supplement 1): 10225–10226.
https://doi.org/10.1182/blood-2022-163572
Published: 2022
Journal Articles

Blockade of the Immune Checkpoint CD47 By TTI-621 Potentiates the Response to Anti-PD-L1 in Cutaneous T Cell Lymphoma

Zhen Han, Xiwei Wu, Yate-Ching Yuan, Hanjun Qin, Chingyu Su, Jasmine Zain, Oleg E Akilov, Steve T Rosen, Mingye Feng, Christiane Querfeld
Journal: Blood
Blood (2022) 140 (Supplement 1): 6376–6377.
https://doi.org/10.1182/blood-2022-167670
Published: 2022
Journal Articles

Phosphorylation Stabilized TET1 Acts As an Oncoprotein and Therapeutic Target in B-Cell Acute Lymphoblastic Leukemia

Zhenhua Chen, Keren Zhou, Jianhuang Xue, Andrew Small, Gang Xiao, Le Xuan Truong Nguyen, Zheng Zhang, Emily Prince, Hengyou Weng, Huilin Huang, Zhicong Zhao, Ying Qing, Chao Shen, Li Han, Brandon Tan, Wei Li, Rui Su, Hanjun Qin, Yangchan Li, Dong Wu, Zhaohui Gu, Vu N Ngo, Xin He, Jianfei Chao, Keith Leung, Kitty Wang, Lei Dong, Xi Qin, Zhenming Cai, Yue Sheng, Yu Chen, Xiwei Wu, Bin Zhang, Yanhong Shi, Guido Marcucci, Zhijian Qian, Mingjiang Xu, Markus Müschen, Xiaolan Deng, Jianjun Chen
Journal: Blood
Blood (2022) 140 (Supplement 1): 998–1000.
https://doi.org/10.1182/blood-2022-165469
Published: 2022
Journal Articles

Genomic Analysis of Cutaneous CD30-Positive Lymphoproliferative Disorders

Farah R Abdulla, Weiwei Zhang, Xiwei Wu, Kord Honda, Hanjun Qin, Hyejin Cho, Christiane Querfeld, Jasmine Zain, Steven T. Rosen, Wing C. Chan, Vishwas Parekh, Joo Y. Song
Journal: Blood
Blood (2021) 138 (Supplement 1): 4487.
https://doi.org/10.1182/blood-2021-152051
Published: 2021
Journal Articles

Suppressing Synthesis of the Long Isoform of the Prolactin Receptor Is a Targeted Strategy to Prevent and Treat B Cell Malignancies

Adeleh Taghi Khani, Anil Kumar, Kelly Radecki, Sung June Lee, Mary Lorenson, Xiwei Wu, Zhaohui Gu, Ameae Walker, Srividya Swaminathan
Journal: Blood
Blood (2021) 138 (Supplement 1): 1135.
https://doi.org/10.1182/blood-2021-147055
Published: 2021
Journal Articles

Tolerogenic anti–IL-2 mAb prevents graft-versus-host disease while preserving strong graft-versus-leukemia activity

Qingxiao Song, Xiaoning Wang, Xiwei Wu, Hanjun Qin, Yingfei Li, Arthur D. Riggs, Paul J. Martin, Yuan-Zhong Chen, Defu Zeng
Journal: Blood
Blood (2021) 137 (16): 2243–2255.
https://doi.org/10.1182/blood.2020006345
Published: 2021
Includes: Supplemental data
Journal Articles

Phase 1 Results of Anti-PD-Ligand 1 (Durvalumab) & Lenalidomide in Patients with Cutaneous T Cell Lymphoma and Correlation with Programmed Death Ligand 1 Expression and Gene Expression Profile

Christiane Querfeld, MDPhD, Ni-Chun Tsai, MS, Joycelynne Palmer, PhD, Xochiquetzal U. Martinez, MD, Farah Abdulla, MD, Xiwei Wu, PhD, Steven T. Rosen, MD, Jasmine Zain, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 20.
https://doi.org/10.1182/blood-2020-143354
Published: 2020
Journal Articles

Paired Single Cell RNA and TCR Sequencing Analysis Following PD-L1 Blockade in Cutaneous T-Cell Lymphoma

Christiane Querfeld, MDPhD, Xiwei Wu, PhD, Hanjun Qin, PhD, Chingyu Su, Zhen Han, Steven T. Rosen, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 21–22.
https://doi.org/10.1182/blood-2020-139992
Published: 2020
Journal Articles

The Involvement of STAT/SOCS Signaling in miRNA-Induced T Cell Exhaustion in Cutaneous T-Cell Lymphoma

Zhen Han, Chingyu Su, Renee J. Estephan, BS, Xiwei Wu, PhD, Sung Hee Kil, PhD, Steven T. Rosen, MD, Christiane Querfeld, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1.
https://doi.org/10.1182/blood-2020-139091
Published: 2020
Journal Articles

Single-Cell Transcriptomics of Human TET2 Knockout CD4 T-Cells and Their Clonal Evolution

Yuping Li, PhD, Xiaoqian Liu, MD PhD, Xuxiang Liu, PhD, Xiwei Wu, PhD, Alyssa Bouska, PhD, Waseem G. Lone, PhD, Chan-Wang J. Lio, PhD, Tyler Herek, BS,MS, Logan Lee, BS, Gehong Dong, MD PhD, Jinhui Wang, PhD, Chih-Hong Lou, PhD, Wei Qi, MD, Kunal Shetty, BS, Timothy W. McKeithan, MD PhD, Javeed Iqbal, PhD, Wing (John) C. Chan, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 22–23.
https://doi.org/10.1182/blood-2020-143113
Published: 2020
Journal Articles

Double-Hit Signature with TP53 Abnormalities Predicts Poor Survival in Patients with Germinal Center Type Diffuse Large B-Cell Lymphoma Treated with R-CHOP

Joo Y Song, MD, Anamarija M. Perry, MD, Alex F. Herrera, MD, Lu Chen, PhD, Pam Skrabek, MD, Michel Nasr, MD, Rebecca Ottesen, Janet Nikowitz, Victoria Bedell, Joyce Murata-Collins, PhD, Yuping Li, PhD, Christine McCarthy, Raju Pillai, MD, Jinhui Wang, PhD, Xiwei Wu, PhD, Jasmine M. Zain, MD, Leslie L. Popplewell, MD FACP, Larry W Kwak, MD PhD, Auayporn P. Nademanee, MDBS, Joyce Niland, PhD, David W. Scott, MBChB, PhD, Qiang Gong, PhD, Wing (John) C. Chan, MD, Dennis D. Weisenburger, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 25–26.
https://doi.org/10.1182/blood-2020-137258
Published: 2020