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Journal Articles

Acquired microRNA (miR)-142 Deficit Drives Immune Escape in Acute Myeloid Leukemia (AML)

Fang Chen, Dandan Zhao, Yongfang Xu, Huafeng Wang, Shawn Sharkas, Le Xuan Truong Nguyen, Lucy Y. Ghoda, Mark Boldin, Guido Marcucci, Bin Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 2944.
https://doi.org/10.1182/blood-2024-210855
Published: 2024
Journal Articles

Deficit of microRNA (miR)-142 Promotes Transformation of Clonal Myeloid Disorder into Acute Myeloid Leukemia (AML)

Yongfang Xu, Huafeng Wang, Fang Chen, Jihyun Irizarry, Shawn Sharkas, Dandan Zhao, Mark Boldin, Guido Marcucci, Bin Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 348.
https://doi.org/10.1182/blood-2024-211467
Published: 2024
Journal Articles

Acquired microRNA-142 Deficit Drives Escape Mechanisms of Anti-Leukemic Surveillance during Blast Crisis Transformation of Chronic Myeloid Leukemia (CML)

Fang Chen, Dandan Zhao, Yi Zhang, Yongfang Xu, Min-Hsuan Chen, Khyatiben V. Pathak, Yong Liang, Wei-Le Wang, Katrina Estrella, Xiwei Wu, Lucy Y. Ghoda, Ya-Huei Kuo, Haris Ali, Jianhua Yu, Michael A Caligiuri, Mark Boldin, Piotr Swiderski, Marcin Kortylewski, Patrick Pirrotte, Le Xuan Truong Nguyen, Guido Marcucci, Bin Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 3152.
https://doi.org/10.1182/blood-2023-182587
Published: 2023
Journal Articles

Microrna-142 Deficiency Promotes Chronic Myeloid Leukemia (CML) Transformation from Chronic Phase (CP) to Blast Crisis (BC)

Bin Amber Zhang, PhD, Dandan Zhao, MD, Huafeng Wang, MD, Chen Liang, MD, Le Xuan Truong Nguyen, PhD, Junjing Qiao, MD PhD, Shanshan Suo, MD, Yasmin Elhajmoussa, Lucy Ghoda, PhD, David Frankhouser, Russell Rockne, PhD, Ling Li, PhD, Ya-Huei Kuo, PhD, Mark Boldin, MD PhD, Guido Marcucci, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 4.
https://doi.org/10.1182/blood-2020-143202
Published: 2020
Journal Articles

Altered microRNA expression links IL6 and TNF-induced inflammaging with myeloid malignancy in humans and mice

Jennifer M. Grants, Joanna Wegrzyn, Tony Hui, Kieran O’Neill, Marion Shadbolt, David J. H. F. Knapp, Jeremy Parker, Yu Deng, Aparna Gopal, T. Roderick Docking, Megan Fuller, Jenny Li, Mark Boldin, Connie J. Eaves, Martin Hirst, Aly Karsan
Journal: Blood
Blood (2020) 135 (25): 2235–2251.
https://doi.org/10.1182/blood.2019003105
Published: 2020
Includes: Supplemental data
Journal Articles

Downregulation of Mir-142 Promotes Leukemia Growth in Philadelphia Chromosome-Positive (Ph+) Acute Lymphoblastic Leukemia (ALL): A Possible Novel Therapeutic Target?

Huafeng Wang, Bin Zhang, PhD, Wei-Le Wang, BS, Dandan Zhao, MD, Ling Li, PhD, Herman Wu, BS, Le Xuan Truong Nguyen, PhD, Weixu Meng, MD PhD, Tinisha McDonald, MS, Flavia Pichiorri, PhD, Ya-Huei Kuo, PhD, Jianjun Chen, PhD, Nadia Carlesso, MD PhD, Ibrahim Aldoss, MD, Vinod A. Pullarkat, MD, Monzr Al Malki, MD, Anthony S. Stein, MD, Mark Boldin, MD PhD, Jie Jin, MD PhD, Guido Marcucci
Journal: Blood
Blood (2018) 132 (Supplement 1): 1338.
https://doi.org/10.1182/blood-2018-99-119599
Published: 2018
Journal Articles

Targeted Delivery of CpG-Mir-146a Mimic Oligonucleotides As a Therapeutic Strategy to Reduce NF-Κb-Mediated Pathogenic Inflammation and Myeloid Leukemia Progression

Yu-Lin SU, PhD, Zhuoran Zhang, PhD, Mati Mann, PhD, Xiuli Wang, PhD, Le Xuan Truong Nguyen, PhD, Bin Zhang, PhD, Ling Li, PhD, Piotr Swiderski, PhD, Mark Boldin, MD PhD, Stephen J Forman, Guido Marcucci, Marcin Kortylewski, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3501.
https://doi.org/10.1182/blood-2018-99-115637
Published: 2018
Journal Articles

Single Cell-Resolution Analysis of HSC Dysfunction in Mir-146a knockout Mice

Jennifer Grants, PhD, Joanna Wegrzyn, PhD, David Knapp, PhD, Tony Hui, Kieran O'Neill, PhD, Jeremy Parker, PhD, Deborah Deng, Mark Boldin, PhD, Martin Hirst, PhD, Connie J. Eaves, PhD, Aly Karsan, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 714.
https://doi.org/10.1182/blood.V130.Suppl_1.714.714
Published: 2017
Journal Articles

Regulation of APC development, immune response, and autoimmunity by Bach1/HO-1 pathway in mice

Alex Yick-Lun So, Yvette Garcia-Flores, Aarathi Minisandram, Ayana Martin, Konstantin Taganov, Mark Boldin, David Baltimore
Journal: Blood
Blood (2012) 120 (12): 2428–2437.
https://doi.org/10.1182/blood-2012-04-426247
Published: 2012
Includes: Supplemental data
Journal Articles

MicroRNA-146a Deficiency Leads to Increased Myeloid Cell Proliferation and Activation

Jimmy L. Zhao, Dinesh S. Rao, M.D., Ph.D., Mark Boldin, Ph.D., Konstantin Taganov, Ph.D., David Baltimore, Ph.D.
Journal: Blood
Blood (2011) 118 (21): 2815.
https://doi.org/10.1182/blood.V118.21.2815.2815
Published: 2011
Journal Articles

MicroRNA-155 Promotes Myeloid Proliferation and Is Overexpressed in Acute Myeloid Leukemia.

Dinesh S. Rao, MD, Ryan M. O’Connell, Ph.D., Aadel A. Chaudhuri, Mark Boldin, Ph.D., Konstantin Taganov, Ph.D., John Nicoll, Ronald Paquette, M.D., David Baltimore, Ph.D.
Journal: Blood
Blood (2007) 110 (11): 715.
https://doi.org/10.1182/blood.V110.11.715.715
Published: 2007