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Journal Articles

Identification of Multivariable microRNA and Clinical Biomarkers Panels to Predict Imatinib Response in Chronic Myeloid Leukemia at Diagnosis

Andrew Wu, Ryan Yen, Sarah Grasedieck, Hanyang Lin, Helen Nakamoto, Donna L. Forrest, Connie J. Eaves, Xiaoyan Jiang

Blood (2023) 142 (Supplement 1): 4547.

https://doi.org/10.1182/blood-2023-180252

Published: 2023

Journal Articles

Single-Cell Revelation of Extensive Heterogeneity in the Human Lymphocyte and Neutrophil/Monocyte Lineage Restriction Process Despite Highly Co-Regulated Changes in Cell Cycle Control

Fangwu Wang, Laura Gonzalez, Martin Hirst, Benjamin D. Simons, Connie J. Eaves

Blood (2023) 142 (Supplement 1): 5581.

https://doi.org/10.1182/blood-2023-190863

Published: 2023

Journal Articles

FLT3-Ligand Alone Enables the Identification and Maintenance in Vitro of Viable Quiescent Human Fetal Liver Hematopoietic Stem Cells with Maintenance of Their Function

Margarita E Macaldaz, Keheng Wang, Jeremy Shu, Paul Miller, Connie J. Eaves

Blood (2023) 142 (Supplement 1): 4046.

https://doi.org/10.1182/blood-2023-190888

Published: 2023

Journal Articles

Aging alters the cell cycle control and mitogenic signaling responses of human hematopoietic stem cells

Colin A. Hammond, Si Wei Wu, Fangwu Wang, Margarita E. MacAldaz, Connie J. Eaves

Blood (2023) 141 (16): 1990–2002.

https://doi.org/10.1182/blood.2022017174

Published: 2023

Includes: Supplemental data

Journal Articles

Identification of Key microRNAs As Predictive Biomarkers of Nilotinib Response in Chronic Myeloid Leukemia: A Sub-Analysis of the Enestxtnd Clinical Trial

Andrew Wu, Ryan Yen, Sarah Grasedieck, Hanyang Lin, Jiechuang Su, Katharina Rothe, Helen Nakamoto, Donna L. Forrest, Connie J. Eaves, Xiaoyan Jiang

Blood (2022) 140 (Supplement 1): 12169–12170.

https://doi.org/10.1182/blood-2022-168534

Published: 2022

Journal Articles

Differential Activation of V γ 4V δ 1 and V γ 9V δ 2 Cord Blood Derived Gamma Delta T Cells upon Exposure to EBV-Lcl and K562 Cells

Jeremy Wee Kiat Ng, Joey Lai, Tony Kiat Hon Lim, William YK Hwang, Shang Li, Connie J. Eaves, Yeow Tee Goh, Alice Cheung

Blood (2021) 138 (Supplement 1): 2790.

https://doi.org/10.1182/blood-2021-152151

Published: 2021

Journal Articles

Single-Cell Analysis of Human B Lymphoid and Neutrophil/Monocyte Lineage Restriction

Fangwu Wang, Colin Hammond, Connie J. Eaves

Blood (2021) 138 (Supplement 1): 4291.

https://doi.org/10.1182/blood-2021-148935

Published: 2021

Journal Articles

MYC-induced human acute myeloid leukemia requires a continuing IL-3/GM-CSF costimulus

Elizabeth Bulaeva, Davide Pellacani, Naoto Nakamichi, Colin A. Hammond, Philip A. Beer, Alireza Lorzadeh, Michelle Moksa, Annaïck Carles, Misha Bilenky, Sylvain Lefort, Jeremy Shu, Brian T. Wilhelm, Andrew P. Weng, Martin Hirst, Connie J. Eaves

Blood (2020) 136 (24): 2764–2773.

https://doi.org/10.1182/blood.2020006374

Published: 2020

Includes: Supplemental data

Journal Articles

Single Cell Immune Profiling Reveals Distinct T Cell Clones and Functional States in in-Vitro Expanded Cord Blood Derived Gamma Delta T Cells

Kar Wai Tan, PhD, Zhihui Li, Joey Lai, Dianyan Guo, Yeh Ching Linn, MBBS, MRCP, William YK Hwang, MBBS, Shang Li, MD PhD, Connie J. Eaves, PhD, Yeow Tee Goh, MBBS, Alice Cheung, PhD

Blood (2020) 136 (Supplement 1): 35–36.

https://doi.org/10.1182/blood-2020-140667

Published: 2020

Journal Articles

The miR-185/PAK6 axis predicts therapy response and regulates survival of drug-resistant leukemic stem cells in CML

Blood (2020) 136 (5): 596–609.

https://doi.org/10.1182/blood.2019003636

Published: 2020

Includes: Supplemental data

Journal Articles

Altered microRNA expression links IL6 and TNF-induced inflammaging with myeloid malignancy in humans and mice

Jennifer M. Grants, Joanna Wegrzyn, Tony Hui, Kieran O’Neill, Marion Shadbolt, David J. H. F. Knapp, Jeremy Parker, Yu Deng, Aparna Gopal, T. Roderick Docking, Megan Fuller, Jenny Li, Mark Boldin, Connie J. Eaves, Martin Hirst, Aly Karsan

Blood (2020) 135 (25): 2235–2251.

https://doi.org/10.1182/blood.2019003105

Published: 2020

Includes: Supplemental data

Journal Articles

NUP98-HOXA9 -Initiates Molecular and Biologic Features of Disease Progression in a Humanized Model of CML

Ivan Sloma, PharmD, PhD, Philip Beer, PhD FRCPath, MRCP, Christophe Desterke, PhD, Elizabeth Bulaeva, Misha Bilenky, Michelle Moksa, Kamini Raghuram, Cedric Brimacombe, Karen Lambie, Ali G Turhan, MD PhD, Orianne Wagner-Ballon, MD PhD, Philippe Gaulard, MD PhD, R. Keith Humphries, MD PhD, Martin Hirst, PhD BS, Connie J. Eaves, PhD

Blood (2019) 134 (Supplement_1): 4139.

https://doi.org/10.1182/blood-2019-127839

Published: 2019

Journal Articles

Growth Factor-Dependent Activation of a MYC-Induced Latent AML Program in Human Hematopoietic Cells

Elizabeth Bulaeva, Davide Pellacani, PhD, Naoto Nakamichi, MD PhD, Philip Beer, MD PhD, Colin Hammond, Alireza Lorzadeh, Michelle Moksa, Annaick Carles, Misha Bilenky, Sylvain Lefort, PhD, Jeremy Shu, Brian T. Wilhelm, PhDBSc, Andrew P. Weng, MD PhD, Martin Hirst, PhD, Connie J. Eaves, PhD

Blood (2019) 134 (Supplement_1): 2533.

https://doi.org/10.1182/blood-2019-122768

Published: 2019

Journal Articles

A topological view of human CD34 + cell state trajectories from integrated single-cell output and proteomic data

David J. H. F. Knapp, Colin A. Hammond, Fangwu Wang, Nima Aghaeepour, Paul H. Miller, Philip A. Beer, Davide Pellacani, Michael VanInsberghe, Carl Hansen, Sean C. Bendall, Garry P. Nolan, Connie J. Eaves

Blood (2019) 133 (9): 927–939.

https://doi.org/10.1182/blood-2018-10-878025

Published: 2019

Includes: Supplemental data

Journal Articles

Global Transcriptome Profiling Identifies a Key Mir-185-PAK6 Axis That Promotes Survival of Leukemic Stem Cells and Drug-Insensitive Blasts in BCR-ABL + Human Leukemia

Andrew Wu, BSc, Lin Hanyang, PhD, Katharina Rothe, PhD, Min Chen, MD PhD, Jens Ruschmann, PhD, Oleh Petriv, PhD, Kieran O'Neill, PhD, Tobias Maetzig, MD, David Knapp, PhD, Naoto Nakamichi, MD PhD, Ryan Brinkman, PhD, Inanc Birol, PhD, Donna L Forrest, MD, Carl Hansen, PhD, R. Keith Humphries, MD PhD, Connie J. Eaves, PhD, Xiaoyan Jiang, MD PhD

Blood (2018) 132 (Supplement 1): 931.

https://doi.org/10.1182/blood-2018-99-113559

Published: 2018

Journal Articles

Synthetic De Novo Modeling of Human T-Cell Acute Lymphoblastic Leukemia Reveals HOXB Genes Drive Expansion of Leukemia Cells-of-Origin and Established Tumor Clones

Blood (2018) 132 (Supplement 1): 1322.

https://doi.org/10.1182/blood-2018-99-120120

Published: 2018

Journal Articles

Genotypic Representation of Myelodysplastic/Myeloproliferative Neoplasms in Nrg, Nrg-3GS and Srg-W41 Mice with Transgenic Expression of Human Cytokines

Hein Than, MD FRCPath, MRCP, Naoto Nakamichi, MD PhD, Anthony D. Pomicter, MS, John O'Shea, PhD, Orlando Antelope, Thomas O'Hare, PhD, Connie J. Eaves, PhD, Michael W. Deininger, MD PhD

Blood (2018) 132 (Supplement 1): 2038.

https://doi.org/10.1182/blood-2018-99-111728

Published: 2018

Journal Articles

Plerixafor effectively mobilizes CD56 bright NK cells in blood, providing an allograft predicted to protect against GVHD

Peggy P. C. Wong, Amina Kariminia, David Jones, Connie J. Eaves, Ronan Foley, Sabine Ivison, Stephen Couban, Kirk R. Schultz

Blood (2018) 131 (25): 2863–2866.

https://doi.org/10.1182/blood-2018-03-836700

Published: 2018

Journal Articles

Single Cell-Resolution Analysis of HSC Dysfunction in Mir-146a knockout Mice

Jennifer Grants, PhD, Joanna Wegrzyn, PhD, David Knapp, PhD, Tony Hui, Kieran O'Neill, PhD, Jeremy Parker, PhD, Deborah Deng, Mark Boldin, PhD, Martin Hirst, PhD, Connie J. Eaves, PhD, Aly Karsan, MD

Blood (2017) 130 (Supplement 1): 714.

https://doi.org/10.1182/blood.V130.Suppl_1.714.714

Published: 2017

Journal Articles

Distinct signaling programs control human hematopoietic stem cell survival and proliferation

David J. H. F. Knapp, Colin A. Hammond, Nima Aghaeepour, Paul H. Miller, Davide Pellacani, Philip A. Beer, Karen Sachs, Wenlian Qiao, WeiJia Wang, R. Keith Humphries, Guy Sauvageau, Peter W. Zandstra, Sean C. Bendall, Garry P. Nolan, Carl Hansen, Connie J. Eaves

Blood (2017) 129 (3): 307–318.

https://doi.org/10.1182/blood-2016-09-740654

Published: 2017

Includes: Supplemental data

NARROW

Identification of Multivariable microRNA and Clinical Biomarkers Panels to Predict Imatinib Response in Chronic Myeloid Leukemia at Diagnosis

Single-Cell Revelation of Extensive Heterogeneity in the Human Lymphocyte and Neutrophil/Monocyte Lineage Restriction Process Despite Highly Co-Regulated Changes in Cell Cycle Control

FLT3-Ligand Alone Enables the Identification and Maintenance in Vitro of Viable Quiescent Human Fetal Liver Hematopoietic Stem Cells with Maintenance of Their Function

Aging alters the cell cycle control and mitogenic signaling responses of human hematopoietic stem cells

Identification of Key microRNAs As Predictive Biomarkers of Nilotinib Response in Chronic Myeloid Leukemia: A Sub-Analysis of the Enestxtnd Clinical Trial

Differential Activation of V γ 4V δ 1 and V γ 9V δ 2 Cord Blood Derived Gamma Delta T Cells upon Exposure to EBV-Lcl and K562 Cells

Single-Cell Analysis of Human B Lymphoid and Neutrophil/Monocyte Lineage Restriction

MYC-induced human acute myeloid leukemia requires a continuing IL-3/GM-CSF costimulus

Single Cell Immune Profiling Reveals Distinct T Cell Clones and Functional States in in-Vitro Expanded Cord Blood Derived Gamma Delta T Cells

The miR-185/PAK6 axis predicts therapy response and regulates survival of drug-resistant leukemic stem cells in CML

Altered microRNA expression links IL6 and TNF-induced inflammaging with myeloid malignancy in humans and mice

NUP98-HOXA9 -Initiates Molecular and Biologic Features of Disease Progression in a Humanized Model of CML

Growth Factor-Dependent Activation of a MYC-Induced Latent AML Program in Human Hematopoietic Cells

A topological view of human CD34 + cell state trajectories from integrated single-cell output and proteomic data

Global Transcriptome Profiling Identifies a Key Mir-185-PAK6 Axis That Promotes Survival of Leukemic Stem Cells and Drug-Insensitive Blasts in BCR-ABL + Human Leukemia

Synthetic De Novo Modeling of Human T-Cell Acute Lymphoblastic Leukemia Reveals HOXB Genes Drive Expansion of Leukemia Cells-of-Origin and Established Tumor Clones

Genotypic Representation of Myelodysplastic/Myeloproliferative Neoplasms in Nrg, Nrg-3GS and Srg-W41 Mice with Transgenic Expression of Human Cytokines

Plerixafor effectively mobilizes CD56 bright NK cells in blood, providing an allograft predicted to protect against GVHD

Single Cell-Resolution Analysis of HSC Dysfunction in Mir-146a knockout Mice

Distinct signaling programs control human hematopoietic stem cell survival and proliferation

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American Society of Hematology

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ASH Publications

American Society of Hematology

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