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Journal Articles

Knockdown of the long isoform of the prolactin receptor selectively targets pathogenic immune cells and averts lupus nephritis

Free
Kory Hamane, Zunsong Hu, Joao Rodrigues Lima-Junior, Adeleh Taghi Khani, Anil Kumar, Ashly Sanchez Ortiz, Da Hae Jung, Hanjun Qin, Shu Tao, Ignacio Sanz, Eric Meffre, Katherine Marzan, Jean Koff, Zhaohui Gu, Xiwei Wu, Ameae Walker, Srividya Swaminathan
Journal: Blood
Blood (2025) 146 (Supplement 1): 3003.
https://doi.org/10.1182/blood-2025-3003
Published: 2025
Journal Articles

Tumor-induced dendritic cell dysfunction impairs T-cell proliferation and confers poor prognosis in high-risk acute lymphoblastic leukemia

Free
Anil Kumar, Kory Hamane, Caroline Duault, Joao Rodrigues Lima-Junior, Da Hae Jung, Hanjun Qin, Sheyla Salcido, Min Huang, Xinying Guo, Adeleh Taghi Khani, Ashly Sanchez Ortiz, Lucy Ghoda, Guido Marcucci, Norman Lacayo, Kathleen Sakamoto, Christian Hurtz, Martin Carroll, Sarah Tasian, Huimin Geng, Lingyun Ji, Saro Armenian, Shai Izraeli, Holden Maecker, Xiwei Wu, Srividya Swaminathan
Journal: Blood
Blood (2025) 146 (Supplement 1): 5138.
https://doi.org/10.1182/blood-2025-5138
Published: 2025
Journal Articles

KMT2A -Rearranged ALL Requires DYRK1A for Regulation of ERK Signaling and Cell Proliferation

Free
Venkata Sesha Sai Abhinav Ayyadevara, Gerald Wertheim, John Chukinas, Joseph Loftus, Sung June Lee, Anil Kumar, Srividya Swaminathan, Rahul S Bhansali, Wayne Childers, Huimin Geng, Thomas A Milne, Xianxin Hua, Kathrin M. Bernt, Thierry Besson, Junwei Shi, John D. Crispino, Martin P Carroll, Sarah K. Tasian, Christian Hurtz
Journal: Blood
Blood (2024) 144 (Supplement 1): 1455.
https://doi.org/10.1182/blood-2024-206134
Published: 2024
Journal Articles

Pharmacologic Inhibition of DYRK1A Results in Hyperactivation and Hyperphosphorylation of MYC and ERK Rendering KMT2A-R ALL Cells Sensitive to BCL2 Inhibition

Free
V. S. S. Abhinav Ayyadevara, Gerald Wertheim, John Chukinas, Joseph Patrick Loftus, Sung June Lee, Anil Kumar, Rahul S. Bhansali, Srividya Swaminathan, Thierry Besson, Junwei Shi, John D. Crispino, Sarah K Tasian, Martin P. Carroll, Christian Hurtz
Journal: Blood
Blood (2022) 140 (Supplement 1): 3486–3488.
https://doi.org/10.1182/blood-2022-162782
Published: 2022
Journal Articles

Pharmacologic Inhibition of DYRK1A Results in Hyperactivation and Hyperphosphorylation of MYC and ERK Rendering KMT2A-R ALL Cells Sensitive to BCL2 Inhibition

Free
Christian Hurtz, Gerald Wertheim, John Chukinas, Joseph Patrick Loftus, Sung June Lee, Anil Kumar, Rahul S. Bhansali, Srividya Swaminathan, Thierry Besson, Junwei Shi, John D. Crispino, Sarah K Tasian, Martin P. Carroll
Journal: Blood
Blood (2021) 138 (Supplement 1): 506.
https://doi.org/10.1182/blood-2021-144476
Published: 2021
Journal Articles

Suppressing Synthesis of the Long Isoform of the Prolactin Receptor Is a Targeted Strategy to Prevent and Treat B Cell Malignancies

Free
Adeleh Taghi Khani, Anil Kumar, Kelly Radecki, Sung June Lee, Mary Lorenson, Xiwei Wu, Zhaohui Gu, Ameae Walker, Srividya Swaminathan
Journal: Blood
Blood (2021) 138 (Supplement 1): 1135.
https://doi.org/10.1182/blood-2021-147055
Published: 2021
Journal Articles

Activated natural killer cells predict poor clinical prognosis in high-risk B- and T-cell acute lymphoblastic leukemia

Free
Caroline Duault, Anil Kumar, Adeleh Taghi Khani, Sung June Lee, Lu Yang, Min Huang, Christian Hurtz, Bryan Manning, Lucy Ghoda, Tinisha McDonald, Norman J. Lacayo, Kathleen M. Sakamoto, Martin Carroll, Sarah K. Tasian, Guido Marcucci, Jianhua Yu, Michael A. Caligiuri, Holden T. Maecker, Srividya Swaminathan
Journal: Blood
Blood (2021) 138 (16): 1465–1480.
https://doi.org/10.1182/blood.2020009871
Published: 2021
Includes: Supplemental data
Journal Articles

DYRK1A Is Required to Alleviate Replication Stress in KMT2A -Rearranged Acute Lymphoblastic Leukemia

Free
Christian Hurtz, PhD, Martin P. Carroll, MD, Sarah K Tasian, MD, Gerald Wertheim, MD, PhD, Rahul S. Bhansali, MDPhD, Sung June Lee, BA, Anil Kumar, PhD, Anne Lehman, Joseph Patrick Loftus, BS, Grace Jeschke, PhD, John D. Crispino, PhD, Thierry Besson, PhD, Junwei Shi, PhD, Srividya Swaminathan, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 39–40.
https://doi.org/10.1182/blood-2020-141258
Published: 2020
Journal Articles

Activated Natural Killer Cells Are Associated with Poor Clinical Prognosis in High-Risk B- and T- Cell Acute Lymphoblastic Leukemia

Free
Caroline Duault, PharmD, PhD, Anil Kumar, PhD, Adeleh Taghi Khani, PhD, Sung June Lee, BA, Lu Yang, PhD, Min Huang, PhD, Christian Hurtz, PhD, Bryan Manning, BS, Lucy Ghoda, PhD, Tinisha McDonald, BS, Norman J. Lacayo, MD, Kathleen M. Sakamoto, MD PhD, Martin P. Carroll, MD, Guido Marcucci, MD, Jianhua Yu, PhD, Michael A. Caligiuri, MD, Holden T. Maecker, PhD, Srividya Swaminathan, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 39.
https://doi.org/10.1182/blood-2020-140044
Published: 2020
Journal Articles

Platelets induce apoptosis via membrane-bound FasL

Free
Rebecca I. Schleicher, Frank Reichenbach, Peter Kraft, Anil Kumar, Mario Lescan, Franziska Todt, Kerstin Göbel, Ingo Hilgendorf, Tobias Geisler, Axel Bauer, Marcus Olbrich, Martin Schaller, Sebastian Wesselborg, Lorraine O’Reilly, Sven G. Meuth, Klaus Schulze-Osthoff, Meinrad Gawaz, Xuri Li, Christoph Kleinschnitz, Frank Edlich, Harald F. Langer
Journal: Blood
Blood (2015) 126 (12): 1483–1493.
https://doi.org/10.1182/blood-2013-12-544445
Published: 2015
Includes: Supplemental data
Journal Articles

Semaphorin 6A regulates angiogenesis by modulating VEGF signaling

Free
Marta Segarra, Hidetaka Ohnuki, Dragan Maric, Ombretta Salvucci, Xu Hou, Anil Kumar, Xuri Li, Giovanna Tosato
Journal: Blood
Blood (2012) 120 (19): 4104–4115.
https://doi.org/10.1182/blood-2012-02-410076
Published: 2012
Includes: Supplemental data
Journal Articles

Post-Renal Transplant De Novo Non-Skin Malignancies in Mycophenolate Mofetil- and Calcineurin Inhibitor-Based Immunosuppression.

Free
Lohith Bachegowda, MD, MRCP, Diptesh Gupta, MD, MRCP, Ajoy Bharadwaj, MD, Karthik Ranganna, TIM Adamowicz, DO, Anil Kumar, MD
Journal: Blood
Blood (2009) 114 (22): 1683.
https://doi.org/10.1182/blood.V114.22.1683.1683
Published: 2009
Journal Articles

VWF-Cleaving Protease ADAMTS13 Reduces Brain Injury Following Ischemic Stroke in Mice: Essential Role for VWF in Stroke

Free
Bing-Qiao Zhao, Anil kumar Chauhan, PhD, Ian S. Patten, Michael Dockal, PhD, Friedrich Scheiflinger, Denisa D. Wagner, Ph.D
Journal: Blood
Blood (2008) 112 (11): 259.
https://doi.org/10.1182/blood.V112.11.259.259
Published: 2008