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Journal Articles

Disruption of cotranscriptional splicing suggests RBM39 is a therapeutic target in acute lymphoblastic leukemia

Blood (2024) 144 (23): 2417–2431.

https://doi.org/10.1182/blood.2024024281

Published: 2024

Includes: Supplemental data

Journal Articles

Modeling GATA2 Deficiency in Mice: The R396Q Mutation Disrupts Normal Hematopoiesis

Trent D Hall, Rashid Mehmood, Diana Sa da Bandeira, Anitria Cotton, Jonathon Klein, Shondra M Pruett-Miller, Shai Izraeli, Wilson K Clements, John D. Crispino

Blood (2024) 144 (Supplement 1): 196.

https://doi.org/10.1182/blood-2024-205815

Published: 2024

Journal Articles

An Essential Role for the N-Terminus of GATA1 in Metabolic Regulation during Erythropoiesis

Te Ling, Lavanya Bezavada, Rashid Mehmood, Kevin Zhang, Jeremy Chase Crawford, Yan Ju, Chun-Wei David Chen, Yichao Li, Yong Cheng, John D. Crispino

Blood (2024) 144 (Supplement 1): 940.

https://doi.org/10.1182/blood-2024-210865

Published: 2024

Journal Articles

Hematopoietic Stem Cells Supporting Fetal Erythropoiesis Are Differentially Regulated By Small and Large Ribosomal Subunits

Yuefeng Tang, Te Ling, Rashid Mehmood, Mushran Khan, Julien Papoin, James Palis, Laurie A. Steiner, Sébastien Durand, Leonard I. Zon, Senthil Velan Bhoopalan, Mitchell J Weiss, Jeffrey Michael Lipton, Naomi Taylor, Patrick G. Gallagher, Mohandas Narla, John D. Crispino, Lionel Blanc

Blood (2024) 144 (Supplement 1): 195.

https://doi.org/10.1182/blood-2024-210699

Published: 2024

Journal Articles

Targeting EBF1-ITGB8 Axis in MPN Bone Marrow Niche

Lyudmila Tsurkan, Melodie Doute, Te Ling, Nicholas Morchel, Amha Atakilit, John D. Crispino, Dean Sheppard, Marta Derecka

Blood (2024) 144 (Supplement 1): 818.

https://doi.org/10.1182/blood-2024-199245

Published: 2024

Journal Articles

Loss of Cystathionine-β-Synthase Activity Results in Increased Oxidative Phosphorylation and Cytarabine Resistance in Myeloid Leukemia Associated with Down Syndrome

Jenna Thibodeau, Jianlei Zhao, Holly Edwards, Lisa Polin, Juiwanna Kushner, Sijana H Dzinic, Kathryn H White, Maik Hüttemann, Tasnim Arroum, Lucynda Pham, Austin C. Boucher, John D. Crispino, Jeffrey W. Taub, Yubin Ge

Blood (2024) 144 (Supplement 1): 1376.

https://doi.org/10.1182/blood-2024-203961

Published: 2024

Journal Articles

A Novel GATA1 (E200K) Germline Mutation Causing Hydrops Fetalis with Spontaneous Resolution of Erythropoiesis

Harry Layton Lesmana, Te Ling, Alexandria Haseley, Marissa Coleridge, John D. Crispino

Blood (2024) 144 (Supplement 1): 1082.

https://doi.org/10.1182/blood-2024-205751

Published: 2024

Journal Articles

KMT2A -Rearranged ALL Requires DYRK1A for Regulation of ERK Signaling and Cell Proliferation

Venkata Sesha Sai Abhinav Ayyadevara, Gerald Wertheim, John Chukinas, Joseph Loftus, Sung June Lee, Anil Kumar, Srividya Swaminathan, Rahul S Bhansali, Wayne Childers, Huimin Geng, Thomas A Milne, Xianxin Hua, Kathrin M. Bernt, Thierry Besson, Junwei Shi, John D. Crispino, Martin P Carroll, Sarah K. Tasian, Christian Hurtz

Blood (2024) 144 (Supplement 1): 1455.

https://doi.org/10.1182/blood-2024-206134

Published: 2024

Journal Articles

Multi-Pronged Effects of Cohesin Mutations in the Myeloid Leukemia of Down Syndrome

Austin C. Boucher, Wojciech Rosikiewicz, Ricky Tirtakusuma, Anitria Cotton, Madeline Niederkorn, Elvin Wagenblast, Paul G. Thomas, Yubin Ge, Jeffrey W. Taub, Jan-Henning Klusmann, John D. Crispino

Blood (2024) 144 (Supplement 1): 2731.

https://doi.org/10.1182/blood-2024-210782

Published: 2024

Journal Articles

Hematopoietic Stem Cell Function and Differentiation Is Regulated By DCAF7 through Polycomb Repressive Complex 1 (PRC1) Modulation

Johanna Melo-Cardenas, Lavanya Bezavada, Te Ling, Amber Broadhurst, Anitria Cotton, Jeremy Chase Crawford, Amanda Nourse, Vishwajeeth Pagala, Qiong Zhang, Wojciech Rosikiewicz, Hongjian Jin, Dirk Loeffler, John D. Crispino

Blood (2024) 144 (Supplement 1): 1272.

https://doi.org/10.1182/blood-2024-210287

Published: 2024

Journal Articles

Malignant progression of preleukemic disorders

Trent Hall, Sandeep Gurbuxani, John D. Crispino

Blood (2024) 143 (22): 2245–2255.

https://doi.org/10.1182/blood.2023020817

Published: 2024

Journal Articles

Upregulation of Platelet Transcripts As Biomarkers of Fibrotic Progression in Myeloproliferative Neoplasms

Anitria Cotton, Ryan Collinson, Lynne Wilson, Zi Yun Ng, Hun S Chuah, Michael F. Leahy, Rebecca Howman, Carolyn Grove, Hasib Sidiqi, Malcolm Webb, Darren Boey, Olivia Ruhen, Michael Phillips, Matthew Linden, Kathy Fuller, Wendy N. Erber, Ronald Hoffman, John D. Crispino, Belinda Guo

Blood (2023) 142 (Supplement 1): 4520.

https://doi.org/10.1182/blood-2023-182140

Published: 2023

Journal Articles

Rps19 and Rpl5 Play Distinct Roles in hematopoietic Stem Cell maintenance and Erythroid Differentiation

Yuefeng Tang, Te Ling, Mushran Khan, Riaz Rao, Vincent P Schulz, Julien Papoin, Anupama Narla, Jeffrey Michael Lipton, James Palis, Laurie A. Steiner, Patrick G Gallagher, Mohandas Narla, John D. Crispino, Lionel Blanc

Blood (2023) 142 (Supplement 1): 144.

https://doi.org/10.1182/blood-2023-189146

Published: 2023

Journal Articles

Chromothripsis Orchestrates Leukemic Transformation in Blast Phase MPN through Targetable Amplification of DYRK1A

Blood (2023) 142 (Supplement 1): 993.

https://doi.org/10.1182/blood-2023-178556

Published: 2023

Journal Articles

Ubiquitin Ligase SCF-FBXO11 Controls a Network of RNA-Binding Proteins and Splicing in MDS

Madeline Niederkorn, Lavanya Bezavada, Anitria Cotton, Lance Palmer, Trent Hall, Michael Schieber, Peng Xu, Mitchell Weiss, Raajit K. Rampal, John D. Crispino

Blood (2023) 142 (Supplement 1): 712.

https://doi.org/10.1182/blood-2023-187094

Published: 2023

Journal Articles

Regulation of Alternative Splicing in B-Cell ALL By DYRK1A

Qi Jin, Ethan Harris, Jacquelyn A. Myers, Anitria Cotton, Jeremy Wen, Johanna Melo-Cardenas, Akihide Yoshimi, Omar Abdel-Wahab, Esther A. Obeng, John D. Crispino

Blood (2023) 142 (Supplement 1): 39.

https://doi.org/10.1182/blood-2023-174923

Published: 2023

Journal Articles

Introduction to a review series on hematopoietic stem cells

John D. Crispino

Blood (2023) 142 (6): 497.

https://doi.org/10.1182/blood.2023020909

Published: 2023

Journal Articles

CALR goes rogue

Johanna Melo-Cardenas, John D. Crispino

Blood (2023) 141 (8): 818–820.

https://doi.org/10.1182/blood.2022018788

Published: 2023

Journal Articles

IL-13/IL-4 signaling contributes to fibrotic progression of the myeloproliferative neoplasms

Johanna Melo-Cardenas, Lavanya Bezavada, Jeremy Chase Crawford, Sandeep Gurbuxani, Anitria Cotton, Guolian Kang, Jeffrey Gossett, Christian Marinaccio, Rona Weinberg, Ronald Hoffman, Anna Rita Migliaccio, Yan Zheng, Marta Derecka, Ciro R. Rinaldi, John D. Crispino

Blood (2022) 140 (26): 2805–2817.

https://doi.org/10.1182/blood.2022017326

Published: 2022

Includes: Supplemental data

Journal Articles

Pharmacologic Inhibition of DYRK1A Results in Hyperactivation and Hyperphosphorylation of MYC and ERK Rendering KMT2A-R ALL Cells Sensitive to BCL2 Inhibition

V. S. S. Abhinav Ayyadevara, Gerald Wertheim, John Chukinas, Joseph Patrick Loftus, Sung June Lee, Anil Kumar, Rahul S. Bhansali, Srividya Swaminathan, Thierry Besson, Junwei Shi, John D. Crispino, Sarah K Tasian, Martin P. Carroll, Christian Hurtz

Blood (2022) 140 (Supplement 1): 3486–3488.

https://doi.org/10.1182/blood-2022-162782

Published: 2022

NARROW

Disruption of cotranscriptional splicing suggests RBM39 is a therapeutic target in acute lymphoblastic leukemia

Modeling GATA2 Deficiency in Mice: The R396Q Mutation Disrupts Normal Hematopoiesis

An Essential Role for the N-Terminus of GATA1 in Metabolic Regulation during Erythropoiesis

Hematopoietic Stem Cells Supporting Fetal Erythropoiesis Are Differentially Regulated By Small and Large Ribosomal Subunits

Targeting EBF1-ITGB8 Axis in MPN Bone Marrow Niche

Loss of Cystathionine-β-Synthase Activity Results in Increased Oxidative Phosphorylation and Cytarabine Resistance in Myeloid Leukemia Associated with Down Syndrome

A Novel GATA1 (E200K) Germline Mutation Causing Hydrops Fetalis with Spontaneous Resolution of Erythropoiesis

KMT2A -Rearranged ALL Requires DYRK1A for Regulation of ERK Signaling and Cell Proliferation

Multi-Pronged Effects of Cohesin Mutations in the Myeloid Leukemia of Down Syndrome

Hematopoietic Stem Cell Function and Differentiation Is Regulated By DCAF7 through Polycomb Repressive Complex 1 (PRC1) Modulation

Malignant progression of preleukemic disorders

Upregulation of Platelet Transcripts As Biomarkers of Fibrotic Progression in Myeloproliferative Neoplasms

Rps19 and Rpl5 Play Distinct Roles in hematopoietic Stem Cell maintenance and Erythroid Differentiation

Chromothripsis Orchestrates Leukemic Transformation in Blast Phase MPN through Targetable Amplification of DYRK1A

Ubiquitin Ligase SCF-FBXO11 Controls a Network of RNA-Binding Proteins and Splicing in MDS

Regulation of Alternative Splicing in B-Cell ALL By DYRK1A

Introduction to a review series on hematopoietic stem cells

CALR goes rogue

IL-13/IL-4 signaling contributes to fibrotic progression of the myeloproliferative neoplasms

Pharmacologic Inhibition of DYRK1A Results in Hyperactivation and Hyperphosphorylation of MYC and ERK Rendering KMT2A-R ALL Cells Sensitive to BCL2 Inhibition

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American Society of Hematology

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American Society of Hematology

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