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Journal Articles

Spatial Transcriptomics Identifies Aberrant Communication between Dendritic Cells and Leukemia Stem Cells As a Therapeutically Targetable Axis in Juvenile Myelomonocytic Leukemia

Blood (2024) 144 (Supplement 1): 822.

https://doi.org/10.1182/blood-2024-208902

Published: 2024

Journal Articles

RUX-AZA Response in AP/BP-MPN Is Driven By Release of the Differentiation Block in Mutant HSPCs: A Single-Cell Multi-Omic Analysis of Responders on the Phase Ib Phazar Study

Blood (2024) 144 (Supplement 1): 3146.

https://doi.org/10.1182/blood-2024-204818

Published: 2024

Journal Articles

Tolerance of Whole Genome Duplication in Megakaryocytes, and Consequences for Their Genome Integrity

Antonio Rodriguez-Romera, Rong Li, Nah-Young Shin, Sally-Ann Clark, Assunta Adamo, Affaf Aliouat, Abdullah Khan, Aude-Anais Olijnik, Jill Brown, Lucia Sommerova, Natalie Jooss, Akiko Shimamura, Xin Lu, Guanlin Wang, Stefan N. Constantinescu, Ketan Patel, Adam J Mead, Alan B. Cantor, Bethan Psaila

Blood (2024) 144 (Supplement 1): 421.

https://doi.org/10.1182/blood-2024-203123

Published: 2024

Journal Articles

KLF5 Is a Key Regulator of IMiD-Induced Neutropenia

Blood (2024) 144 (Supplement 1): 2527.

https://doi.org/10.1182/blood-2024-207135

Published: 2024

Journal Articles

Constructing a Computational Workflow for the Identification of Novel Cellular and Molecular Drivers of Human Granulopoiesis

Blood (2024) 144 (Supplement 1): 2525.

https://doi.org/10.1182/blood-2024-207224

Published: 2024

Journal Articles

Platelets Sequester Extracellular DNA, Capturing Tumour-Derived and Free Fetal DNA

Blood (2023) 142 (Supplement 1): 277.

https://doi.org/10.1182/blood-2023-182697

Published: 2023

Journal Articles

Platelet-Restricted Clonal Hematopoiesis

Nikolaos Sousos, Lauren Murphy, Sean Wen, Angela Hamblin, Sally-Ann Clark, Christina Simoglou Karali, Jessica Whittle, Zemin Ren, Haseeb Rahman, Nawshad Hayder, Akriti Rastogi, Michael Jacobs, Susan Shapiro, Bethan Psaila, Adam J Mead

Blood (2023) 142 (Supplement 1): 814.

https://doi.org/10.1182/blood-2023-188000

Published: 2023

Journal Articles

Chromothripsis Orchestrates Leukemic Transformation in Blast Phase MPN through Targetable Amplification of DYRK1A

Blood (2023) 142 (Supplement 1): 993.

https://doi.org/10.1182/blood-2023-178556

Published: 2023

Journal Articles

A Multiomic Single-Cell Atlas of Human Myelopoiesis Reveals Cellular and Molecular Drivers of Immunomodulatory Drug-Induced Neutropenia

Christina Simoglou Karali, Simone Riva, Sally-Ann Clark, Sean Wen, Nikolaos Sousos, Eleni Louka, E. Ravza Gür, Nawshad Hayder, William E. Pierceall, Anjan Thakurta, Anita K. Gandhi, Patrick R Hagner, Jim Hughes, Adam J Mead

Blood (2023) 142 (Supplement 1): 935.

https://doi.org/10.1182/blood-2023-182041

Published: 2023

Journal Articles

Cooperation between SF3B1 and JAK2 V617F Mutations Accelerates Fibrotic Progression in Myeloproliferative Neoplasms By Enhancing STAT1 Signaling

Jennifer O Sullivan, Sean Wen, Affaf Aliouat, Alba Rodriguez-Meira, Sally-Ann Clark, Neil Ashley, Amy Wood, Ramy Slama, Guanlin Wang, Angela Hamblin, Lauren Murphy, Christina Simoglou Karali, Charlotte K Brierley, Adam P Cribbs, Aimee Paterson, Claire N Harrison, Bethan Psaila, Adam J Mead

Blood (2023) 142 (Supplement 1): 861.

https://doi.org/10.1182/blood-2023-185118

Published: 2023

Journal Articles

Single-Cell Transcriptome Analysis Reveals Pathways That Drive Dyserythropoiesis in Myelodysplastic Syndromes, Which Are Targeted By Luspatercept

Onima Chowdhury, Douglas RA Silveira, Sophie Reed, Jennifer O'Sullivan, Sally-Ann Clark, Neil Ashley, Bethan Psaila, Supat Thongjuea, Adam J Mead, Lynn Quek

Blood (2022) 140 (Supplement 1): 9753–9754.

https://doi.org/10.1182/blood-2022-165865

Published: 2022

Journal Articles

Cross-Talk between Hematopoietic Cells and Fibroblast Subsets Drives Inflammation and Remodelling of the Bone Marrow Microenvironment in Myeloproliferative Neoplasms

Blood (2022) 140 (Supplement 1): 1091–1092.

https://doi.org/10.1182/blood-2022-165493

Published: 2022

Journal Articles

Canonical Notch signaling is dispensable for adult steady-state and stress myelo-erythropoiesis

Blood (2018) 131 (15): 1712–1719.

https://doi.org/10.1182/blood-2017-06-788505

Published: 2018

Includes: Supplemental data

Journal Articles

Single Cell Whole Transcriptome Analysis Reveals Distinct Molecular Signatures of Therapy-Resistant Chronic Myeloid Leukemia Stem Cells

Alice Giustacchini, Supat Thongjuea, Petter S. Woll, PhD, Paul Sopp, Ana Duenas Perez, Nikolaos Barkas, Christopher Booth, Ruggiero Norfo, Sally-Ann Clark, Lauren Jamieson, Sten Eirik Jacobsen, Adam Mead

Blood (2015) 126 (23): 13.

https://doi.org/10.1182/blood.V126.23.13.13

Published: 2015

Journal Articles

Characterisation of the Stem and Progenitor Cell Hierarchy in Patients with CMML

Onima Chowdhury, MD PhD, Petter S Woll, PhD, Una Kjällquist, PhD, Helen Doolittle, MD, Rikard Erlandsson, PhD, Kristina Anderson, MD PhD, Ingunn Dybedal, MD PhD, Adam Mead, MDPhD, Sally-Ann Clark, PhD, Mette S. Holm, MD PhD, Peter Hokland, MD DMSc, Lars Nilsson, MD PhD, Sten Linnarsson, PhD, Eva Hellstrom-Lindberg, MD PhD, Sten Eirik W Jacobsen, MD PhD

Blood (2014) 124 (21): 1896.

https://doi.org/10.1182/blood.V124.21.1896.1896

Published: 2014

Journal Articles

Diverse Genetic Lesions In Myelodysplastic Syndromes Originate Exclusively In Rare MDS Stem Cells

Blood (2013) 122 (21): 4195.

https://doi.org/10.1182/blood.V122.21.4195.4195

Published: 2013

NARROW

Spatial Transcriptomics Identifies Aberrant Communication between Dendritic Cells and Leukemia Stem Cells As a Therapeutically Targetable Axis in Juvenile Myelomonocytic Leukemia

RUX-AZA Response in AP/BP-MPN Is Driven By Release of the Differentiation Block in Mutant HSPCs: A Single-Cell Multi-Omic Analysis of Responders on the Phase Ib Phazar Study

Tolerance of Whole Genome Duplication in Megakaryocytes, and Consequences for Their Genome Integrity

KLF5 Is a Key Regulator of IMiD-Induced Neutropenia

Constructing a Computational Workflow for the Identification of Novel Cellular and Molecular Drivers of Human Granulopoiesis

Platelets Sequester Extracellular DNA, Capturing Tumour-Derived and Free Fetal DNA

Platelet-Restricted Clonal Hematopoiesis

Chromothripsis Orchestrates Leukemic Transformation in Blast Phase MPN through Targetable Amplification of DYRK1A

A Multiomic Single-Cell Atlas of Human Myelopoiesis Reveals Cellular and Molecular Drivers of Immunomodulatory Drug-Induced Neutropenia

Cooperation between SF3B1 and JAK2 V617F Mutations Accelerates Fibrotic Progression in Myeloproliferative Neoplasms By Enhancing STAT1 Signaling

Single-Cell Transcriptome Analysis Reveals Pathways That Drive Dyserythropoiesis in Myelodysplastic Syndromes, Which Are Targeted By Luspatercept

Cross-Talk between Hematopoietic Cells and Fibroblast Subsets Drives Inflammation and Remodelling of the Bone Marrow Microenvironment in Myeloproliferative Neoplasms

Canonical Notch signaling is dispensable for adult steady-state and stress myelo-erythropoiesis

Single Cell Whole Transcriptome Analysis Reveals Distinct Molecular Signatures of Therapy-Resistant Chronic Myeloid Leukemia Stem Cells

Characterisation of the Stem and Progenitor Cell Hierarchy in Patients with CMML

Diverse Genetic Lesions In Myelodysplastic Syndromes Originate Exclusively In Rare MDS Stem Cells

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American Society of Hematology

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ASH Publications

American Society of Hematology

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