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Jim Hughes
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Journal Articles

KLF5 Is a Key Regulator of IMiD-Induced Neutropenia

Christina Simoglou Karali, Simone G Riva, Sally-Ann Clark, E. Ravza Gür, Nicholas Denny, Roman Doll, Anastasia Kosmidou, Assunta Adamo, Shady Adnan Awad, Srinivasa Adusumalli, Jiangpeikun Song, Sean Wen, Nikolaos Sousos, Eleni Louka, Nawshad Hayder, Kim Sharp, William E. Pierceall, Anjan Thakurta, Anita K. Gandhi, Patrick R. Hagner, James Oliver Davies, Kilian Huber, Jim Hughes, Adam J Mead
Journal: Blood
Blood (2024) 144 (Supplement 1): 2527.
https://doi.org/10.1182/blood-2024-207135
Published: 2024
Journal Articles

Constructing a Computational Workflow for the Identification of Novel Cellular and Molecular Drivers of Human Granulopoiesis

Simone G Riva, Christina Simoglou Karali, E. Ravza Gür, Martin Sergeant, Edward Sanders, Sally-Ann Clark, Nicholas Denny, Roman Doll, Anastasia Kosmidou, Assunta Adamo, Shady Adnan Awad, Srinivasa Adusumalli, Jiangpeikun Song, Sean Wen, Nikolaos Sousos, Eleni Louka, Nawshad Hayder, Kim Sharp, William E. Pierceall, Anjan Thakurta, Anita K. Gandhi, Patrick R. Hagner, James Oliver Davies, Kilian Huber, Adam J Mead, Jim Hughes
Journal: Blood
Blood (2024) 144 (Supplement 1): 2525.
https://doi.org/10.1182/blood-2024-207224
Published: 2024
Journal Articles

Sustained MYB Activity Is Necessary for Oncogenic Transcription in KMT2A -Rearranged Acute Lymphoblastic Leukemia through Enhancer-Promoter Interactions and Epigenetic Modifications at Enhancers

I-Jun Lau, Joe R Harman, Nicole E Jackson, Nicholas Denny, Alastair L Smith, Paresh Vyas, James Oliver Davies, Jim Hughes, Nicholas Crump, Thomas Arthur Milne
Journal: Blood
Blood (2023) 142 (Supplement 1): 40.
https://doi.org/10.1182/blood-2023-185172
Published: 2023
Journal Articles

A Multiomic Single-Cell Atlas of Human Myelopoiesis Reveals Cellular and Molecular Drivers of Immunomodulatory Drug-Induced Neutropenia

Christina Simoglou Karali, Simone Riva, Sally-Ann Clark, Sean Wen, Nikolaos Sousos, Eleni Louka, E. Ravza Gür, Nawshad Hayder, William E. Pierceall, Anjan Thakurta, Anita K. Gandhi, Patrick R Hagner, Jim Hughes, Adam J Mead
Journal: Blood
Blood (2023) 142 (Supplement 1): 935.
https://doi.org/10.1182/blood-2023-182041
Published: 2023
Journal Articles

Tissue-specific histone modification and transcription factor binding in α globin gene expression

Marco De Gobbi, Eduardo Anguita, Jim Hughes, Jacqueline A. Sloane-Stanley, Jacqueline A. Sharpe, Christoph M. Koch, Ian Dunham, Richard J. Gibbons, William G. Wood, Douglas R. Higgs
Journal: Blood
Blood (2007) 110 (13): 4503–4510.
https://doi.org/10.1182/blood-2007-06-097964
Published: 2007
Includes: Supplemental data