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Journal Articles

BCMA Mutational Screening Reveals Differential Cytotoxic Activity between T-Cell Engagers in Preclinical Co-Culture Models

Vinidhra Sridharan, Hsiling Chiu, Shirong Li, Chad C. Bjorklund, Anita K. Gandhi, Patrick R. Hagner

Blood (2024) 144 (Supplement 1): 4650.

https://doi.org/10.1182/blood-2024-211024

Published: 2024

Journal Articles

Golcadomide-Mediated Degradation of Aiolos/Ikaros Synergizes with BET Inhibitors through Bidirectional Restructuring of the Directly Regulated Epigenetic Environment in DLBCL

Chih-Chao Hsu, Junfei Zhao, Ann Polonskaia, Chad C. Bjorklund, Maria Ortiz Estevez, Anita K. Gandhi, Patrick R. Hagner

Blood (2024) 144 (Supplement 1): 2739.

https://doi.org/10.1182/blood-2024-200270

Published: 2024

Journal Articles

KLF5 Is a Key Regulator of IMiD-Induced Neutropenia

Blood (2024) 144 (Supplement 1): 2527.

https://doi.org/10.1182/blood-2024-207135

Published: 2024

Journal Articles

Constructing a Computational Workflow for the Identification of Novel Cellular and Molecular Drivers of Human Granulopoiesis

Blood (2024) 144 (Supplement 1): 2525.

https://doi.org/10.1182/blood-2024-207224

Published: 2024

Journal Articles

Degradation of Ikaros Induces Neutropenia through Altered Transcriptional Programming across Multiple Stages of Neutrophil Development and Maturation

Ajit Dhadve, Neelam Kumari, Swati Mahapatra, Amrutha Y, Riddhita Deb, Gobinathan Rengarasu, Vakkil Mariyappan, Ramya V, Swetha Muralidhar, Preethi Kulothungan, Gaurav Jain, Anita K. Gandhi, Patrick R. Hagner, Sambuddho Mukherjee

Blood (2024) 144 (Supplement 1): 2523.

https://doi.org/10.1182/blood-2024-207493

Published: 2024

Journal Articles

Deciphering the Mechanism of Action of the Novel Celmod, Golcadomide, during Germinal Center B Cell Immune Response and in a Preclinical Mouse Model of Follicular Lymphoma

Caroline Huber, Yumi Nakayama, Camille Soun, Noushin Mossadegh-Keller, Sophie Guia, Melanie Collin, Alexandre Sarrabay, Lionel Chasson, Lionel Spinelli, Bertrand Nadel, Anita K. Gandhi, Gabriel Brisou, Patrick R. Hagner, Sandrine Roulland

Blood (2024) 144 (Supplement 1): 955.

https://doi.org/10.1182/blood-2024-209884

Published: 2024

Journal Articles

Golcadomide Extends Survival of Lymphoma GEMM Mice in Combination with a CD20xCD3 T-Cell Bispecific through Increased T-Cell Activation and Infiltration

Yumi Nakayama, Ajit Dhadve, Wen Liu, Lei Wu, Neelam Kumari, Amrutha Y, Riddhita Deb, Vijayaragavan Appanasamy, Laura Armstrong, Asier Antoranz, Mark Kaplan, Sambuddho Mukherjee, Anita K. Gandhi, Patrick R. Hagner

Blood (2024) 144 (Supplement 1): 1617.

https://doi.org/10.1182/blood-2024-200370

Published: 2024

Journal Articles

Genomic and Single Cell Investigation of MRD Clonality in Genetically Engineered Mouse Models of Multiple Myeloma

Junfei Zhao, Marta Larrayoz, Chad C. Bjorklund, Anita K. Gandhi, Jose A. Martinez-Climent, Patrick R. Hagner, Maria Ortiz

Blood (2024) 144 (Supplement 1): 1409.

https://doi.org/10.1182/blood-2024-210958

Published: 2024

Journal Articles

Multi-Omics Integration to Elucidate the Cis-Regulatory Network Re-Wiring upon NSD2 Degradation in t(4;14) Multiple Myeloma

Bo Hu, Hardik Modi, Diana Jankeel, Jacob T. Edwards, Junfei Zhao, Chad C. Bjorklund, Gaurav Jain, Patrick R. Hagner, Maria Ortiz, Zhongying Mo, Celia Fontanillo, Christoph W. Zapf, Antonia Lopez-Girona, Neil Bence, Kai Wang, Anita K. Gandhi, Mark Rolfe, Deborah S. Mortensen, Lynda Groocock

Blood (2024) 144 (Supplement 1): 1881.

https://doi.org/10.1182/blood-2024-203621

Published: 2024

Journal Articles

Differential Chromatin Organization between t(4;14) and Non-t(4;14) Multiple Myeloma Driven By the Histone Methyltransferase NSD2

Chad C. Bjorklund, Junfei Zhao, Gaurav Jain, Natasha Shtraizent, Maria Ortiz, Sambuddo Mukherjee, Patrick R Hagner, Anita K. Gandhi

Blood (2023) 142 (Supplement 1): 3295.

https://doi.org/10.1182/blood-2023-190137

Published: 2023

Journal Articles

Mezigdomide Reverses T-Cell Exhaustion through Degradation of Aiolos/Ikaros and Reinvigoration of Cytokine Production Pathways

Hsiling Chiu, Junfei Zhao, Maria Ortiz Estevez, Patrick R Hagner, Anita K. Gandhi

Blood (2023) 142 (Supplement 1): 335.

https://doi.org/10.1182/blood-2023-189445

Published: 2023

Journal Articles

Celmod Induced Disruption of Granulopoiesis Continuum Identified Using Humanized Cereblon Mice

Ajit Dhadve, Neelam Kumari, Amrutha Y, Riddhita Deb, Gobinathan Rengarasu, Ramya V, Swetha Muralidhar, Shwetank Verma, Patrick R Hagner, Sambuddo Mukherjee, Anita K. Gandhi

Blood (2023) 142 (Supplement 1): 5586.

https://doi.org/10.1182/blood-2023-189539

Published: 2023

Journal Articles

Investigation of the Synergistic Combination of a Novel Celmod (CC-99282) and BET Inhibitors in Preclinical DLBCL

Chih-Chao Hsu, Hsiling Chiu, Chad C. Bjorklund, Patrick R Hagner, Anita K. Gandhi

Blood (2023) 142 (Supplement 1): 5719.

https://doi.org/10.1182/blood-2023-189191

Published: 2023

Journal Articles

Emergence of Highly-Plastic B Cell States Cooperates with Early Immune Microenvironment Remodeling to Drive Follicular Lymphomagenesis

Blood (2023) 142 (Supplement 1): 717.

https://doi.org/10.1182/blood-2023-185829

Published: 2023

Journal Articles

Iberdomide Enhances Dara Mediated Cytotoxicity through Upregulation of CDC Activity and Elevated NK Cell Mediated ADCC

Peilin Ma, Vinidhra Sridharan, Krista Wollerman, Debjani Dutta, Ram Kumar Singh, Sambuddo Mukherjee, Chad C. Bjorklund, Patrick R Hagner, Michael Amatangelo, Anita K. Gandhi

Blood (2023) 142 (Supplement 1): 3289.

https://doi.org/10.1182/blood-2023-189423

Published: 2023

Journal Articles

Fedratinib Overcomes Ruxolitinib Resistance through Inhibition of the Interferon Signaling Pathway

Danny Jeyaraju, Ann Polonskaia, Chih-Chao Hsu, Patrick R Hagner, Anita K. Gandhi

Blood (2023) 142 (Supplement 1): 1434.

https://doi.org/10.1182/blood-2023-181898

Published: 2023

Journal Articles

A Multiomic Single-Cell Atlas of Human Myelopoiesis Reveals Cellular and Molecular Drivers of Immunomodulatory Drug-Induced Neutropenia

Christina Simoglou Karali, Simone Riva, Sally-Ann Clark, Sean Wen, Nikolaos Sousos, Eleni Louka, E. Ravza Gür, Nawshad Hayder, William E. Pierceall, Anjan Thakurta, Anita K. Gandhi, Patrick R Hagner, Jim Hughes, Adam J Mead

Blood (2023) 142 (Supplement 1): 935.

https://doi.org/10.1182/blood-2023-182041

Published: 2023

Journal Articles

Overcoming IMiD resistance in T-cell lymphomas through potent degradation of ZFP91 and IKZF1

Blood (2022) 139 (13): 2024–2037.

https://doi.org/10.1182/blood.2021014701

Published: 2022

Includes: Supplemental data

Journal Articles

Triggering interferon signaling in T cells with avadomide sensitizes CLL to anti-PD-L1/PD-1 immunotherapy

Blood (2021) 137 (2): 216–231.

https://doi.org/10.1182/blood.2020006073

Published: 2021

Includes: Supplemental data

Journal Articles

Leveraging gene expression subgroups to classify DLBCL patients and select for clinical benefit from a novel agent

Alberto Risueño, Patrick R. Hagner, Fadi Towfic, Celia Fontanillo, Amira Djebbari, Joel S. Parker, Clifton P. Drew, Grzegorz S. Nowakowski, Matthew J. Maurer, James R. Cerhan, Xin Wei, Yan Ren, Chung-Wein Lee, Suzana Couto, Maria Wang, Michael Pourdehnad, Anita K. Gandhi, Matthew W. B. Trotter

Blood (2020) 135 (13): 1008–1018.

https://doi.org/10.1182/blood.2019002414

Published: 2020

Includes: Supplemental data

NARROW

BCMA Mutational Screening Reveals Differential Cytotoxic Activity between T-Cell Engagers in Preclinical Co-Culture Models

Golcadomide-Mediated Degradation of Aiolos/Ikaros Synergizes with BET Inhibitors through Bidirectional Restructuring of the Directly Regulated Epigenetic Environment in DLBCL

KLF5 Is a Key Regulator of IMiD-Induced Neutropenia

Constructing a Computational Workflow for the Identification of Novel Cellular and Molecular Drivers of Human Granulopoiesis

Degradation of Ikaros Induces Neutropenia through Altered Transcriptional Programming across Multiple Stages of Neutrophil Development and Maturation

Deciphering the Mechanism of Action of the Novel Celmod, Golcadomide, during Germinal Center B Cell Immune Response and in a Preclinical Mouse Model of Follicular Lymphoma

Golcadomide Extends Survival of Lymphoma GEMM Mice in Combination with a CD20xCD3 T-Cell Bispecific through Increased T-Cell Activation and Infiltration

Genomic and Single Cell Investigation of MRD Clonality in Genetically Engineered Mouse Models of Multiple Myeloma

Multi-Omics Integration to Elucidate the Cis-Regulatory Network Re-Wiring upon NSD2 Degradation in t(4;14) Multiple Myeloma

Differential Chromatin Organization between t(4;14) and Non-t(4;14) Multiple Myeloma Driven By the Histone Methyltransferase NSD2

Mezigdomide Reverses T-Cell Exhaustion through Degradation of Aiolos/Ikaros and Reinvigoration of Cytokine Production Pathways

Celmod Induced Disruption of Granulopoiesis Continuum Identified Using Humanized Cereblon Mice

Investigation of the Synergistic Combination of a Novel Celmod (CC-99282) and BET Inhibitors in Preclinical DLBCL

Emergence of Highly-Plastic B Cell States Cooperates with Early Immune Microenvironment Remodeling to Drive Follicular Lymphomagenesis

Iberdomide Enhances Dara Mediated Cytotoxicity through Upregulation of CDC Activity and Elevated NK Cell Mediated ADCC

Fedratinib Overcomes Ruxolitinib Resistance through Inhibition of the Interferon Signaling Pathway

A Multiomic Single-Cell Atlas of Human Myelopoiesis Reveals Cellular and Molecular Drivers of Immunomodulatory Drug-Induced Neutropenia

Overcoming IMiD resistance in T-cell lymphomas through potent degradation of ZFP91 and IKZF1

Triggering interferon signaling in T cells with avadomide sensitizes CLL to anti-PD-L1/PD-1 immunotherapy

Leveraging gene expression subgroups to classify DLBCL patients and select for clinical benefit from a novel agent

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American Society of Hematology

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ASH Publications

American Society of Hematology

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