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Journal Articles

Golcadomide Extends Survival of Lymphoma GEMM Mice in Combination with a CD20xCD3 T-Cell Bispecific through Increased T-Cell Activation and Infiltration

Yumi Nakayama, Ajit Dhadve, Wen Liu, Lei Wu, Neelam Kumari, Amrutha Y, Riddhita Deb, Vijayaragavan Appanasamy, Laura Armstrong, Asier Antoranz, Mark Kaplan, Sambuddho Mukherjee, Anita K. Gandhi, Patrick R. Hagner
Journal: Blood
Blood (2024) 144 (Supplement 1): 1617.
https://doi.org/10.1182/blood-2024-200370
Published: 2024
Journal Articles

Single-Cell Atlas of Diffuse Large B-Cell Lymphoma Reveals Integrated Malignant B Cell and Tumor Microenvironment Characteristics Associated with Clinical Response

Sabrina Baaklini, Alexandre Sarrabay, Adrien Mazuel, Bertrand Escaliere, Chuang Dong, Camille Barthelemy, Laurine Gil, Laila Dahbi, Noushin Mossadegh-Keller, Nathalie Van Acker, Pauline Gravelle, Jean-Marc Navarro, Caroline Huber, Romain Fenouil, Romane Trombetta, Marine Pujol, Philippe Gaulard, Benjamin Riviere, Peggy Dartigues, Francesco Llamas Gutierrez, Celine Pangault, Fabrice Jardin, François Lemonnier, Gilles Salles, Corinne Haioun, Gabriel Brisou, Matthew E. Stokes, Sahil Seth, Maria Ortiz Estevez, Camille Laurent, Lionel Spinelli, Mark Kaplan, C. Chris Huang, Anita K. Gandhi, Bertrand Nadel, Sandrine Roulland, Pierre Milpied
Journal: Blood
Blood (2024) 144 (Supplement 1): 1597.
https://doi.org/10.1182/blood-2024-209815
Published: 2024
Journal Articles

A Single Cell Atlas of Follicular Lymphoma across Clinical Stages Defines Tumor B Cell Archetypes, Immune Microenvironment Heterogeneity and Novel Cell States Associated with High-Risk FL

Alexandre Sarrabay, Sabrina Baaklini, Camille Barthelemy, Laurine Gil, Alicia Beyou, Laila Dahbi, Noushin Mossadegh-Keller, Caroline Huber, Jean-Marc Navarro, Gilles Salles, Gabriel Brisou, Maria Ortiz Estevez, Matthew E. Stokes, Sahil Seth, C. Chris Huang, Mark Kaplan, Lionel Spinelli, Anita K. Gandhi, Bertrand Nadel, Pierre Milpied, Sandrine Roulland
Journal: Blood
Blood (2024) 144 (Supplement 1): 740.
https://doi.org/10.1182/blood-2024-209642
Published: 2024
Journal Articles

Golcadomide (GOLCA) Plus R-CHOP Has High Minimal Residual Disease (MRD) Negativity across High-Risk, Untreated Aggressive B-Cell Lymphoma (a-BCL)

Arnaud Amzallag, Tara Basavanhally, Jason R. Westin, Marc Hoffmann, Theodoros P. Vassilakopoulos, Javier Munoz, Grzegorz S. Nowakowski, Floriane Boucaud, Matt Stokes, Akshay Sudhindra, Anita K. Gandhi, Mark Kaplan
Journal: Blood
Blood (2024) 144 (Supplement 1): 579.
https://doi.org/10.1182/blood-2024-203135
Published: 2024
Journal Articles

Pharmacodynamic Biomarkers and CtDNA Support the Mechanism of Action and Clinical Efficacy of Golcadomide (CC-99282) Combined with R-CHOP in Previously Untreated Aggressive B-Cell Lymphoma

Mark Kaplan, Tara Basavanhally, Yumi Nakayama, Charalampos Kyriakopoulos, Arnaud Amzallag, Argyrios Gkasiamis, Arpankumar Patel, Akshay Sudhindra, Grzegorz S. Nowakowski, Jason Westin, Anita K. Gandhi
Journal: Blood
Blood (2023) 142 (Supplement 1): 1631.
https://doi.org/10.1182/blood-2023-180231
Published: 2023
Journal Articles

Golcadomide (GOLCA; CC-99282), a Novel CELMoD Agent, Plus R-CHOP in Patients (pts) with Previously Untreated Aggressive B-Cell Lymphoma (a-BCL): Safety and Efficacy Results from Phase 1b Dose Expansion

Marc S. Hoffmann, Javier L. Munoz, Jason Westin, Theodoros Vassilakopoulos, Alejandro Martin Garcia-Sancho, Antonio Rueda Dominguez, Wojciech Jurczak, Su-Peng Yeh, Maria Bouzani, Argyrios Gkasiamis, Mark Kaplan, Arpankumar Patel, Floriane Boucaud, Ju Li, Grzegorz S. Nowakowski
Journal: Blood
Blood (2023) 142 (Supplement 1): 4459.
https://doi.org/10.1182/blood-2023-174242
Published: 2023
Journal Articles

Iberdomide (CC-220) Monotherapy or in Combination with an Anti-CD20 Monoclonal Antibody As Effective Therapy in Patients with Relapsed/Refractory Lymphoma: Early Results from a Phase 1/2 Study

Catherine Thieblemont, Javier Munoz, Alessandra Tucci, Carlo Visco, Guillaume Cartron, Paolo Corradini, Ian W. Flinn, Thomas Gastinne, Kamal Krimo Bouabdallah,, Luca Arcaini, Grzegorz S. Nowakowski, Louise Roulin, Max Topp, Shekeab Jauhari, Vladan Vucinic, Peter Martin, Argyrios Gkasiamis, James Drew, Parth Rao, Mark Kaplan, Yiming Cheng, Ju Li, Franck Morschhauser
Journal: Blood
Blood (2022) 140 (Supplement 1): 569–572.
https://doi.org/10.1182/blood-2022-162559
Published: 2022
Journal Articles

Recovery of Highly Functional Human Hematopoietic Stem and Progenitor Cells from 27-Year Old Cryopreserved Umbilical Cord Blood

Hal E. Broxmeyer, Larry L Luchsinger, Rona S Weinberg, Alexandra Jimenez, Emeline Masson Frenet, Mark Kaplan, Scott Cooper, James Ropa
Journal: Blood
Blood (2022) 140 (Supplement 1): 10437–10438.
https://doi.org/10.1182/blood-2022-170272
Published: 2022
Journal Articles

Extracellular DEK Activates NRF2 Antioxidant Targets and Drives Expansion of Functional and ROS-Low Human Hematopoietic Stem Cells

James Ropa, Sarah Gutch, Lindsay Beasley, Paola Aguilar Neuville, Scott Cooper, Di Cao, Wouter van't Hof, Maureen Legendre, Mark Kaplan, David M Markovitz, Maegan L. Capitano
Journal: Blood
Blood (2022) 140 (Supplement 1): 8576–8577.
https://doi.org/10.1182/blood-2022-170089
Published: 2022
Journal Articles

Connect ® Lymphoma Disease Registry: A US-Based, Prospective, Observational Cohort Study

Christopher R. Flowers, David Andorsky, John M. Burke, James R. Cerhan, David L. Grinblatt, Chris L. Pashos, Kathleen Toomey, Andrew D. Zelenetz, Kristen Sullivan, E. Dawn Flick, Pavel Kiselev, Mark Kaplan, Jung Ryun Ahn
Journal: Blood
Blood (2021) 138 (Supplement 1): 1460.
https://doi.org/10.1182/blood-2021-145135
Published: 2021
Journal Articles

PAK1 Regulates Eotaxin-Mediated Murine Eosinophil Migration in Vitro and In Vivo

Muithi Mwanthi, Gracie Michels, Karl Staser, PhD, Sarita Sehra, PhD, Michal Jander, Shi Chen, PhD, David S Wilkes, MD, Mark Kaplan, PhD, Su-jung Park, PhD, D. Wade Clapp, MD
Journal: Blood
Blood (2011) 118 (21): 18.
https://doi.org/10.1182/blood.V118.21.18.18
Published: 2011
Journal Articles

Lymphoid Precursors Arise Independently at Multiple Sites During Development.

Prashanth Porayette, MD, PhD, Momoko Yoshimoto, MD, PhD, Nicole Glosson, Michael Ferkowicz, William C. Shelley, Mark Kaplan, PhD, Mervin C. Yoder, MD
Journal: Blood
Blood (2009) 114 (22): 699.
https://doi.org/10.1182/blood.V114.22.699.699
Published: 2009
Journal Articles

Focal Adhesion Kinase Regulates Critical Functions in Hematopoiesis.

Sasidhar Vemula, PhD, Benjamin P. Abratigue, BS, Premchand Gandra, BS, John T. O’Malley, MD/PhD, Ayek-Nati N. Ahyi, PhD, Gretta Stritesky, PhD, Norman Yeh, PhD, Mark Kaplan, MD/PhD, Hillary Beggs, PhD, Reuben Kapur, PhD
Journal: Blood
Blood (2007) 110 (11): 1407.
https://doi.org/10.1182/blood.V110.11.1407.1407
Published: 2007
Journal Articles

ROCKI Regulates Critical Functions in Macrophages and Neutrophils.

Sasidhar Vemula, PhD, Premchand Gandra, BS, Jianjian Shi, MD/PhD, John T. O’Malley, MD/PhD, Ayek-Nati N. Ahyi, PhD, Gretta Stritesky, PhD, Norman Yeh, PhD, Mark Kaplan, MD/PhD, Lei Wei, MD/PhD, Reuben Kapur, PhD
Journal: Blood
Blood (2007) 110 (11): 2406.
https://doi.org/10.1182/blood.V110.11.2406.2406
Published: 2007