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Journal Articles

The DPP4 Dependent Transcriptome Identifies Pathways to Improve Mouse Hematopoietic Cell Function

James Ropa, Scott Cooper, Maegan L Capitano, Mark H Kaplan

Blood (2023) 142 (Supplement 1): 3420.

https://doi.org/10.1182/blood-2023-191156

Published: 2023

Journal Articles

Recovery of Highly Functional Human Hematopoietic Stem and Progenitor Cells from 27-Year Old Cryopreserved Umbilical Cord Blood

Hal E. Broxmeyer, Larry L Luchsinger, Rona S Weinberg, Alexandra Jimenez, Emeline Masson Frenet, Mark Kaplan, Scott Cooper, James Ropa

Blood (2022) 140 (Supplement 1): 10437–10438.

https://doi.org/10.1182/blood-2022-170272

Published: 2022

Journal Articles

Extracellular DEK Activates NRF2 Antioxidant Targets and Drives Expansion of Functional and ROS-Low Human Hematopoietic Stem Cells

James Ropa, Sarah Gutch, Lindsay Beasley, Paola Aguilar Neuville, Scott Cooper, Di Cao, Wouter van't Hof, Maureen Legendre, Mark Kaplan, David M Markovitz, Maegan L. Capitano

Blood (2022) 140 (Supplement 1): 8576–8577.

https://doi.org/10.1182/blood-2022-170089

Published: 2022

Journal Articles

Transferrin-induced thrombosis in hypoxia

Scott Cooper

Blood (2022) 140 (19): 2006–2008.

https://doi.org/10.1182/blood.2022018181

Published: 2022

Journal Articles

Physioxia-induced downregulation of Tet2 in hematopoietic stem cells contributes to enhanced self-renewal

Arafat Aljoufi, Chi Zhang, James Ropa, Wennan Chang, Lakshmi Reddy Palam, Scott Cooper, Baskar Ramdas, Maegan L. Capitano, Hal E. Broxmeyer, Reuben Kapur

Blood (2022) 140 (11): 1263–1277.

https://doi.org/10.1182/blood.2022015499

Published: 2022

Includes: Supplemental data

Journal Articles

Preliminary Results of a Phase 1 Study in Healthy Subjects Administered Inclacumab, a Fully Human IgG4 Anti-P-Selectin Monoclonal Antibody in Development for Treatment of Sickle Cell Disease

Christina Mayer, Daniel Scott Cooper, Andrew Redfern, Xin Geng, Jianxia Shi, Mariëlle van Zutphen-van Geffen, Isabelle Kuan, Kathleen Koeck, Helen Kastrissios, Kashyap Patel, Mark Davis, Patrick Yue

Blood (2021) 138 (Supplement 1): 977.

https://doi.org/10.1182/blood-2021-153370

Published: 2021

Journal Articles

Extracellular DEK Treatment Mimics Hypoxic Blockade of Extra Physiologic Oxygen Stress in Human and Mouse Hematopoietic Cells

James Ropa, Scott Cooper, Lindsay Beasley, David M Markovitz, Hal E. Broxmeyer, Maegan L. Capitano

Blood (2021) 138 (Supplement 1): 2152.

https://doi.org/10.1182/blood-2021-151171

Published: 2021

Journal Articles

Leptin Receptor As a Marker for a Subset of Long-Term Functional Hematopoietic Stem Cells

Thao Trinh, BS, James Ropa, BS, MSc, PhD, Arafat Aljoufi, MD, Scott Cooper, MS, Edward F. Srour, PhD, Anthony Sinn, BS, Hal E. Broxmeyer, PhD

Blood (2020) 136 (Supplement 1): 31–32.

https://doi.org/10.1182/blood-2020-139595

Published: 2020

Journal Articles

Sars-Cov-2 Spike Protein Induces Cellular Changes in Primitive and Mature Hematopoietic Cells

James Ropa, BS, MSc, PhD, Scott Cooper, MS, Maegan L. Capitano, PhD, Hal E. Broxmeyer, PhD

Blood (2020) 136 (Supplement 1): 25–26.

https://doi.org/10.1182/blood-2020-142415

Published: 2020

Journal Articles

Leptin Receptor As a Functional Marker for Long-Term Repopulating Hematopoietic Stem Cells

Thao Trinh, BS, Scott Cooper, MS, Arafat Aljoufi, MD, Edward F. Srour, PhD, Hal E. Broxmeyer, PhD

Blood (2019) 134 (Supplement_1): 3712.

https://doi.org/10.1182/blood-2019-128659

Published: 2019

Journal Articles

Hematopoietic Stem and Progenitor Cells Manifest Direct Migration Towards Secreted DEK in a CXCR2- and G Protein Signaling-Dependent Manner

Maegan L. Capitano, PhD, Yasser Sammour, Maureen Legendre, Scott Cooper, MS, David Markovitz, MD, Hal E. Broxmeyer, PhD

Blood (2019) 134 (Supplement_1): 1196.

https://doi.org/10.1182/blood-2019-128738

Published: 2019

Journal Articles

Collection and Processing of Bone Marrow at 3% Oxygen Significantly Alters the Manifestation of Aged Mouse Hematopoietic Stem Cell Phenotype

Maegan L. Capitano, PhD, Scott Cooper, M.S., Bin Guo, PhD, Xinxin Huang, PhD, Carol Sampson, MS, Safa Mohamad, Edward F. Srour, PhD, Christie M. Orschell, PhD, Hal E. Broxmeyer, PhD

Blood (2019) 134 (Supplement_1): 1202.

https://doi.org/10.1182/blood-2019-128642

Published: 2019

Journal Articles

Chromatin Remodeling Subunit Brm Regulates Hematopoietic Stem Cell Self-Renewal By Limiting Intracellular Valine Levels

Samisubbu R Naidu, PhD, Maegan L. Capitano, PhD, Scott Cooper, MS, Xinxin Huang, PhD, Hal E. Broxmeyer, PhD

Blood (2019) 134 (Supplement_1): 3702.

https://doi.org/10.1182/blood-2019-128867

Published: 2019

Journal Articles

CD166 Engagement Augments Mouse and Human Hematopoietic Stem and Progenitor Function Via Activation of Stem Cell-Associated and Cell Cycle Pathways

Joydeep Ghosh, PhD, Jing Zhang, PhD, Chi Zhang, PhD, Xinxin Huang, PhD, Safa F. Mohamad, MS, Maegan L. Capitano, PhD, Andrea M. Gunawan, Scott Cooper, MS, Bin Guo, PhD, Qingchun Cai, PhD, Hal E. Broxmeyer, PhD, Edward F. Srour, PhD

Blood (2018) 132 (Supplement 1): 1282.

https://doi.org/10.1182/blood-2018-99-119251

Published: 2018

Journal Articles

Phosphatidylinositol transfer proteins regulate megakaryocyte TGF-β1 secretion and hematopoiesis in mice

Maegan Capitano, Liang Zhao, Scott Cooper, Chelsea Thorsheim, Aae Suzuki, Xinxin Huang, Alexander L. Dent, Michael S. Marks, Charles S. Abrams, Hal E. Broxmeyer

Blood (2018) 132 (10): 1027–1038.

https://doi.org/10.1182/blood-2017-09-806257

Published: 2018

Includes: Supplemental data

Journal Articles

Mitigating Detrimental Influences of Ambient Air Collection of Bone Marrow By Hypoxic Collection Results in Detection of Functionally Enhanced Aged Mouse Hematopoiesis: Reflecting Stem Cell Expression Levels of CXCR4, CCR5 and ROS

Maegan Capitano, PhD, Scott Cooper, MS, Bin Guo, PhD, Jing Zhang, PhD, Xinxin Huang, PhD, Qingchun Cai, PhD, Heather A. O'Leary, PhD, Hui Lin Chua, PhD, Artur Plett, PhD, Christie M. Orschell, PhD, Hal E. Broxmeyer, PhD

Blood (2017) 130 (Supplement 1): 2420.

https://doi.org/10.1182/blood.V130.Suppl_1.2420.2420

Published: 2017

Journal Articles

Extracellular DEK Regulates Hematopoiesis through CXCR2-Mediated Intracellular Signaling That Does Not Require Its Translocation into the Nucleus or Binding to DNA

Maegan Capitano, PhD, Nirit Mor-Vaknin, PhD, Maureen Legendre, Scott Cooper, MS, Ferdinand Kappes, PhD, David Markovitz, MD, Hal E. Broxmeyer, PhD

Blood (2017) 130 (Supplement 1): 3770.

https://doi.org/10.1182/blood.V130.Suppl_1.3770.3770

Published: 2017

Journal Articles

Re-Evaluation of Age-Related Dysregulation of Hematopoiesis Based on Oxygen Induced Changes Associated with Cell Collection/Processing in Ambient Air

Hal E. Broxmeyer, PhD, Maegan L. Capitano, PhD, Heather A. O'leary, PhD, Scott Cooper, MAS, Hui Lin Chua, PhD, Artur Plett, PhD, Christie M. Orschell, PhD

Blood (2016) 128 (22): 5051.

https://doi.org/10.1182/blood.V128.22.5051.5051

Published: 2016

Journal Articles

Human Hematopoietic Stem Cell Homing and Engraftment Promoted By Glucocorticoid Induced Chromatin Remodeling

Bin Guo, PhD, Xinxin Huang, PhD, Scott Cooper, MAS, Hal E. Broxmeyer, PhD

Blood (2016) 128 (22): 494.

https://doi.org/10.1182/blood.V128.22.494.494

Published: 2016

Journal Articles

DEK Regulates Hematopoietic Stem and Progenitor Cell Fate By Activating AKT and ERK Mediated Signaling through CXCR2/Heparan Sulfate Proteoglycans

Maegan L. Capitano, PhD, Nirit Mor-Vaknin, Maureen Legendre, Scott Cooper, MAS, David Markovitz, MD, Hal E. Broxmeyer, PhD

Blood (2016) 128 (22): 2645.

https://doi.org/10.1182/blood.V128.22.2645.2645

Published: 2016

NARROW

The DPP4 Dependent Transcriptome Identifies Pathways to Improve Mouse Hematopoietic Cell Function

Recovery of Highly Functional Human Hematopoietic Stem and Progenitor Cells from 27-Year Old Cryopreserved Umbilical Cord Blood

Extracellular DEK Activates NRF2 Antioxidant Targets and Drives Expansion of Functional and ROS-Low Human Hematopoietic Stem Cells

Transferrin-induced thrombosis in hypoxia

Physioxia-induced downregulation of Tet2 in hematopoietic stem cells contributes to enhanced self-renewal

Preliminary Results of a Phase 1 Study in Healthy Subjects Administered Inclacumab, a Fully Human IgG4 Anti-P-Selectin Monoclonal Antibody in Development for Treatment of Sickle Cell Disease

Extracellular DEK Treatment Mimics Hypoxic Blockade of Extra Physiologic Oxygen Stress in Human and Mouse Hematopoietic Cells

Leptin Receptor As a Marker for a Subset of Long-Term Functional Hematopoietic Stem Cells

Sars-Cov-2 Spike Protein Induces Cellular Changes in Primitive and Mature Hematopoietic Cells

Leptin Receptor As a Functional Marker for Long-Term Repopulating Hematopoietic Stem Cells

Hematopoietic Stem and Progenitor Cells Manifest Direct Migration Towards Secreted DEK in a CXCR2- and G Protein Signaling-Dependent Manner

Collection and Processing of Bone Marrow at 3% Oxygen Significantly Alters the Manifestation of Aged Mouse Hematopoietic Stem Cell Phenotype

Chromatin Remodeling Subunit Brm Regulates Hematopoietic Stem Cell Self-Renewal By Limiting Intracellular Valine Levels

CD166 Engagement Augments Mouse and Human Hematopoietic Stem and Progenitor Function Via Activation of Stem Cell-Associated and Cell Cycle Pathways

Phosphatidylinositol transfer proteins regulate megakaryocyte TGF-β1 secretion and hematopoiesis in mice

Mitigating Detrimental Influences of Ambient Air Collection of Bone Marrow By Hypoxic Collection Results in Detection of Functionally Enhanced Aged Mouse Hematopoiesis: Reflecting Stem Cell Expression Levels of CXCR4, CCR5 and ROS

Extracellular DEK Regulates Hematopoiesis through CXCR2-Mediated Intracellular Signaling That Does Not Require Its Translocation into the Nucleus or Binding to DNA

Re-Evaluation of Age-Related Dysregulation of Hematopoiesis Based on Oxygen Induced Changes Associated with Cell Collection/Processing in Ambient Air

Human Hematopoietic Stem Cell Homing and Engraftment Promoted By Glucocorticoid Induced Chromatin Remodeling

DEK Regulates Hematopoietic Stem and Progenitor Cell Fate By Activating AKT and ERK Mediated Signaling through CXCR2/Heparan Sulfate Proteoglycans

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American Society of Hematology

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ASH Publications

American Society of Hematology

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