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Journal Articles

Isatuximab Plus Bortezomib, Lenalidomide, and Dexamethasone (Isa-VRd) Versus Vrd in Chinese Patients with Newly Diagnosed Multiple Myeloma Who Are Ineligible for Transplant: IMROZ Subgroup Analysis

Gang An, Zhuogang Liu, Jie Jin, Zhen Cai, Wei Li, Zhongjun Xia, Xinan Cen, Yu Hu, Jian-Qing Mi, Hongmei Jing, Rong Zhan, Xiaoyan Qu, Xin Du, Dan Gao, Liang Zhao, Lugui Qiu

Blood (2024) 144 (Supplement 1): 7055.

https://doi.org/10.1182/blood-2024-199908

Published: 2024

Journal Articles

First-in-Human Phase 1 Study of SAR442257 in Patients with Relapsed/Refractory Multiple Myeloma and Non-Hodgkin Lymphoma

Blood (2024) 144 (Supplement 1): 1992.

https://doi.org/10.1182/blood-2024-204614

Published: 2024

Journal Articles

PSAT1 Suppression Drives a Targetable Serine Dependence in AML

Ilias Sinanidis, Panagiotis Tsakiroglou, Rebecca Foertsch, Julia Gondek, Benjamin Dubner, InYoung Choi, Bogdan Paun, Liang Zhao, Everett Stone, George Georgiou, Gabriel Ghiaur, William Brian Dalton

Blood (2024) 144 (Supplement 1): 1383.

https://doi.org/10.1182/blood-2024-211885

Published: 2024

Journal Articles

Pitpβ Loss Ameliorates Jak2 V617F-Induced Myeloproliferative Neoplasms (MPN) in Mice

Nikita Vantsev, Liang Zhao, Charles S. Abrams, Wei Tong

Blood (2024) 144 (Supplement 1): 1753.

https://doi.org/10.1182/blood-2024-207836

Published: 2024

Journal Articles

Phosphatidylinositol transfer proteins regulate megakaryocyte TGF-β1 secretion and hematopoiesis in mice

Maegan Capitano, Liang Zhao, Scott Cooper, Chelsea Thorsheim, Aae Suzuki, Xinxin Huang, Alexander L. Dent, Michael S. Marks, Charles S. Abrams, Hal E. Broxmeyer

Blood (2018) 132 (10): 1027–1038.

https://doi.org/10.1182/blood-2017-09-806257

Published: 2018

Includes: Supplemental data

Journal Articles

Pleckstrin-2 Plays an Essential Role in the Pathogenesis of JAK2 V617F -Induced Myeloproliferative Neoplasms

Baobing Zhao, PhD, Yang Mei, PhD, Ronen Sumagin, PhD, Jing Yang, Chelsea Thorsheim, Liang Zhao, PhD, Timothy J. Stalker, PhD, Jeremy Q. Wen, John Crispino, PhD MBA, Charles S. Abrams, MD, Peng Ji, MD PhD

Blood (2016) 128 (22): 798.

https://doi.org/10.1182/blood.V128.22.798.798

Published: 2016

Journal Articles

Platelet Pitp-Alpha Promotes Thrombin Generation and the Dissemination of Tumor Metastasis, but Has Minimal Effect on Vascular Plug Formation

Liang Zhao, PhD, Lurong Lian, Aae Suzuki, Timothy J. Stalker, PhD, Sang H Min, MD, Sriram Krishnaswamy, PhD MD, Amy Durham, VMD, Charles S. Abrams, MD

Blood (2015) 126 (23): 418.

https://doi.org/10.1182/blood.V126.23.418.418

Published: 2015

Journal Articles

Role for Megakaryocyte Phosphatidylinositol Transfer Proteins-Alpha and -Beta in TGF Beta-Mediated Regulation of Hematopoietic Homeostasis

Hal E. Broxmeyer, PhD, Maegan L. Capitano, PhD, Liang Zhao, PhD, Scott Cooper, MAS, Charles S. Abrams, MD

Blood (2015) 126 (23): 780.

https://doi.org/10.1182/blood.V126.23.780.780

Published: 2015

Journal Articles

Platelet Pitpa Is Not Essential for Hemostasis, but Is Required for Tumor Metastasis Formation

Liang Zhao, PhD, Aae Suzuki, Timothy J. Stalker, PhD, Lurong Lian, MD, Min Sang, MD, Amy C Durham, VMD, Charles S. Abrams, MD

Blood (2014) 124 (21): 342.

https://doi.org/10.1182/blood.V124.21.342.342

Published: 2014

Journal Articles

Loss Of Phosphatidylinositol Transfer Proteins (PITPs) Causes Thrombocytopenia Due To a Defect In Thrombopoiesis

Aae Suzuki, Liang Zhao, Ph.D., Yuhuan Wang, PhD, Lurong Lian, Sang H. Min, MD, Mortimer Poncz, MD, Charles S. Abrams, MD

Blood (2013) 122 (21): 2313.

https://doi.org/10.1182/blood.V122.21.2313.2313

Published: 2013

Journal Articles

Pikfyve Deletion In Platelets Causes Aberrant Platelet Lysosomal Storage Associated With Inappropriate Inflammatory Response

Sang H Min, MD, Aae Suzuki, Timothy J. Stalker, PhD, Jessica Guzman, Liang Zhao, Ph.D., Lurong Lian, Ronghua Meng, PhD, Michael S. Marks, PhD, John K Choi, MD, PhD, Charles S. Abrams, MD

Blood (2013) 122 (21): 24.

https://doi.org/10.1182/blood.V122.21.24.24

Published: 2013

Journal Articles

Platelets lacking PIP5KIγ have normal integrin activation but impaired cytoskeletal-membrane integrity and adhesion

Yanfeng Wang, Liang Zhao, Aae Suzuki, Lurong Lian, Sang H. Min, Ziqian Wang, Rustem I. Litvinov, Timothy J. Stalker, Tadayuki Yago, Arkadiusz G. Klopocki, David W. Schmidtke, Helen Yin, John K. Choi, Rodger P. McEver, John W. Weisel, John H. Hartwig, Charles S. Abrams

Blood (2013) 121 (14): 2743–2752.

https://doi.org/10.1182/blood-2012-07-445205

Published: 2013

Includes: Supplemental data

Journal Articles

RhoA Is Essential for Maintaining Normal Megakaryocyte Ploidy Distribution and Platelet Generation

Aae Suzuki, Jae-Won Shin, Ph.D., Yuhuan Wang, PhD, Mortimer Poncz, MD, John K. Choi, MD, PhD, Dennis E Discher, Ph.D., Christopher L. Carpenter, MD, PhD, Lurong Lian, Liang Zhao, Ph.D., Yanfeng Wang, Charles S. Abrams, MD

Blood (2012) 120 (21): 385.

https://doi.org/10.1182/blood.V120.21.385.385

Published: 2012

Journal Articles

Class I Phosphatidylinositol Transfer Proteins (PITPs) Promote Platelet Activation by Functioning As Essential Cofactors for Phospholipid Kinases and Hydrolases

Liang Zhao, Ph.D., Lurong Lian, M.D., Aae Suzuki, Charles S. Abrams, MD

Blood (2012) 120 (21): 91.

https://doi.org/10.1182/blood.V120.21.91.91

Published: 2012

Journal Articles

Pikfyve-Deficient Platelets Mediate Inflammation and Thrombosis by Releasing Aberrant Granules

Sang H Min, MD, Aae Suzuki, Liang Zhao, Ph.D., Lurong Lian, Timothy J. Stalker, PhD, John K. Choi, MD, PhD, Charles S. Abrams, MD

Blood (2012) 120 (21): 262.

https://doi.org/10.1182/blood.V120.21.262.262

Published: 2012

Journal Articles

Class I Phosphatidylinositol Transfer Proteins (PITPs) Promote PIP2 Synthesis and IP3 Production in Mouse Platelets

Liang Zhao, Ph.D., Lurong Liang, M.D., Aae Suzuki, Sang Min, MD, Charles S. Abrams, MD

Blood (2011) 118 (21): 363.

https://doi.org/10.1182/blood.V118.21.363.363

Published: 2011

Journal Articles

Loss of PIKFyve Kinase Function Driven by Platelet Factor 4 Promoter Results in Platelet Lysosomal Storage Defects and Infiltration of Multiple Organs with Vacuolated Macrophages

Sang Min, MD, Aae Suzuki, Liang Zhao, Ph.D., Lurong Lian, Timothy J. Stalker, PhD, John K. Choi, MD, PhD, Charles S. Abrams, MD

Blood (2011) 118 (21): 697.

https://doi.org/10.1182/blood.V118.21.697.697

Published: 2011

Journal Articles

Mice That Lack RhoA In Their Platelets Have Normal Actin Dynamics, but Have Macrothrombocytopenia

Aae Suzuki, Lurong Lian, Liang Zhao, Sang H. Min, MD, Yuhuan Wang, Mortimer Poncz, MD, John K Choi, Christopher L. Carpenter, MD, PhD, Charles S. Abrams, MD

Blood (2010) 116 (21): 549.

https://doi.org/10.1182/blood.V116.21.549.549

Published: 2010

Journal Articles

Loss of PIKFyve In Murine Platelets Leads to Aberrant Platelet Granule Biogenesis and a Pleomorphic Phenotype with Multiorgan Failure

Sang H. Min, MD, Aae Suzuki, Liang Zhao, Lurong Lian, Sidney W. Whiteheart, PhD, Michael S. Marks, PhD, John K. Choi, MD, PhD, Charles S. Abrams, MD

Blood (2010) 116 (21): 159.

https://doi.org/10.1182/blood.V116.21.159.159

Published: 2010

Journal Articles

Hematopoietic stem cell function requires 12/15-lipoxygenase–dependent fatty acid metabolism

Michelle Kinder, Cong Wei, Suresh G. Shelat, Mondira Kundu, Liang Zhao, Ian A. Blair, Ellen Puré

Blood (2010) 115 (24): 5012–5022.

https://doi.org/10.1182/blood-2009-09-243139

Published: 2010

Includes: Supplemental data

NARROW

Isatuximab Plus Bortezomib, Lenalidomide, and Dexamethasone (Isa-VRd) Versus Vrd in Chinese Patients with Newly Diagnosed Multiple Myeloma Who Are Ineligible for Transplant: IMROZ Subgroup Analysis

First-in-Human Phase 1 Study of SAR442257 in Patients with Relapsed/Refractory Multiple Myeloma and Non-Hodgkin Lymphoma

PSAT1 Suppression Drives a Targetable Serine Dependence in AML

Pitpβ Loss Ameliorates Jak2 V617F-Induced Myeloproliferative Neoplasms (MPN) in Mice

Phosphatidylinositol transfer proteins regulate megakaryocyte TGF-β1 secretion and hematopoiesis in mice

Pleckstrin-2 Plays an Essential Role in the Pathogenesis of JAK2 V617F -Induced Myeloproliferative Neoplasms

Platelet Pitp-Alpha Promotes Thrombin Generation and the Dissemination of Tumor Metastasis, but Has Minimal Effect on Vascular Plug Formation

Role for Megakaryocyte Phosphatidylinositol Transfer Proteins-Alpha and -Beta in TGF Beta-Mediated Regulation of Hematopoietic Homeostasis

Platelet Pitpa Is Not Essential for Hemostasis, but Is Required for Tumor Metastasis Formation

Loss Of Phosphatidylinositol Transfer Proteins (PITPs) Causes Thrombocytopenia Due To a Defect In Thrombopoiesis

Pikfyve Deletion In Platelets Causes Aberrant Platelet Lysosomal Storage Associated With Inappropriate Inflammatory Response

Platelets lacking PIP5KIγ have normal integrin activation but impaired cytoskeletal-membrane integrity and adhesion

RhoA Is Essential for Maintaining Normal Megakaryocyte Ploidy Distribution and Platelet Generation

Class I Phosphatidylinositol Transfer Proteins (PITPs) Promote Platelet Activation by Functioning As Essential Cofactors for Phospholipid Kinases and Hydrolases

Pikfyve-Deficient Platelets Mediate Inflammation and Thrombosis by Releasing Aberrant Granules

Class I Phosphatidylinositol Transfer Proteins (PITPs) Promote PIP2 Synthesis and IP3 Production in Mouse Platelets

Loss of PIKFyve Kinase Function Driven by Platelet Factor 4 Promoter Results in Platelet Lysosomal Storage Defects and Infiltration of Multiple Organs with Vacuolated Macrophages

Mice That Lack RhoA In Their Platelets Have Normal Actin Dynamics, but Have Macrothrombocytopenia

Loss of PIKFyve In Murine Platelets Leads to Aberrant Platelet Granule Biogenesis and a Pleomorphic Phenotype with Multiorgan Failure

Hematopoietic stem cell function requires 12/15-lipoxygenase–dependent fatty acid metabolism

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American Society of Hematology

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