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Journal Articles

Pitpβ Loss Ameliorates Jak2 V617F-Induced Myeloproliferative Neoplasms (MPN) in Mice

Nikita Vantsev, Liang Zhao, Charles S. Abrams, Wei Tong
Journal: Blood
Blood (2024) 144 (Supplement 1): 1753.
https://doi.org/10.1182/blood-2024-207836
Published: 2024
Journal Articles

CBL Loss or Mutations Reduces MHCII Expression through Downregulating ERG in Myeloid Malignancies

Rouxing Wang, Mohammed Alhusayan, Bowen Xing, Emma Hedgepeth, Yan Liu, Hamid Band, Laurence Eisenlohr, Junwei Shi, Irfan Asangani, Wei Tong
Journal: Blood
Blood (2024) 144 (Supplement 1): 2730.
https://doi.org/10.1182/blood-2024-208798
Published: 2024
Journal Articles

CBL Loss or Mutations Upregulates AXL to Promote Cytokine-Independent Growth in Myeloid Malignancies: AXL Upregulation Promotes Cytokine-Independent Growth in CBL -Mutant CMML

Rouxing Wang, Shiwei Chen, Mohammed Alhusayan, Bowen Xing, Yan Liu, Hamid Band, Irfan Asangani, Junwei Shi, Wei Tong
Journal: Blood
Blood (2024) 144 (Supplement 1): 4574.
https://doi.org/10.1182/blood-2024-209140
Published: 2024
Journal Articles

Hidden conformational codes

Kaosheng Lv, Wei Tong
Journal: Blood
Blood (2023) 142 (21): 1766–1768.
https://doi.org/10.1182/blood.2023022061
Published: 2023
Journal Articles

Lnk/Sh2b3 Deficiency Increases DNA Damage Tolerance to Promote Hematopoietic Stem Cell Fitness

Md Akram Hossain, Brijendra Singh, Jeremie Fages, Carlo Salas Salinas, Xiao Hua Liang, Wei Tong
Journal: Blood
Blood (2023) 142 (Supplement 1): 32.
https://doi.org/10.1182/blood-2023-190875
Published: 2023
Journal Articles

Reducing DNA Damage Associated with Endogenous Genotoxic Stress in Hematopoietic Stem Cells

Brijendra Singh, Carlo Salas Salinas, Md Akram Hossain, Christopher Millington, Ketan Patel, Wei Tong
Journal: Blood
Blood (2023) 142 (Supplement 1): 1361.
https://doi.org/10.1182/blood-2023-188029
Published: 2023
Journal Articles

PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371

Hongxia Chen, Yunpeng Bai, Michihiro Kobayashi, Shiyu Xiao, Wenjie Cai, Sergio Barajas, Sisi Chen, Jinmin Miao, Frederick Nguele Meke, Sasidhar Vemula, James P. Ropa, James M. Croop, H. Scott Boswell, Jun Wan, Yuzhi Jia, Huiping Liu, Loretta S. Li, Jessica K. Altman, Elizabeth A. Eklund, Peng Ji, Wei Tong, Hamid Band, Danny T. Huang, Leonidas C. Platanias, Zhong-Yin Zhang, Yan Liu
Journal: Blood
Blood (2023) 141 (3): 244–259.
https://doi.org/10.1182/blood.2022016580
Published: 2023
Includes: Supplemental data
Journal Articles

Waking up CML leukemia stem cells for the kill

Kaosheng Lv, Wei Tong
Journal: Blood
Blood (2022) 139 (5): 647–648.
https://doi.org/10.1182/blood.2021014629
Published: 2022
Journal Articles

Depalmitoylation rewires FLT3-ITD signaling and exacerbates leukemia progression

Kaosheng Lv, Jian-Gang Ren, Xu Han, Jun Gui, Chujie Gong, Wei Tong
Journal: Blood
Blood (2021) 138 (22): 2244–2255.
https://doi.org/10.1182/blood.2021011582
Published: 2021
Includes: Supplemental data
Journal Articles

RUNX-1 haploinsufficiency causes a marked deficiency of megakaryocyte-biased hematopoietic progenitor cells

Brian Estevez, Sara Borst, Danuta Jarocha, Varun Sudunagunta, Michael Gonzalez, James Garifallou, Hakon Hakonarson, Peng Gao, Kai Tan, Paul Liu, Sumedha Bagga, Nicholas Holdreith, Wei Tong, Nancy Speck, Deborah L. French, Paul Gadue, Mortimer Poncz
Journal: Blood
Blood (2021) 137 (19): 2662–2675.
https://doi.org/10.1182/blood.2020006389
Published: 2021
Includes: Supplemental data
Journal Articles

The BRISC deubiquitinating enzyme complex limits hematopoietic stem cell expansion by regulating JAK2 K63-ubiquitination

Ryan Donaghy, Xu Han, Krasimira Rozenova, Kaosheng Lv, Qinqin Jiang, Miriam Doepner, Roger A. Greenberg, Wei Tong
Journal: Blood
Blood (2019) 133 (14): 1560–1571.
https://doi.org/10.1182/blood-2018-10-877563
Published: 2019
Includes: Supplemental data
Journal Articles

Janus Kinase (Jak) 1 Inhibition Affects Both Megakaryopoiesis and Thrombopoiesis

Danuta Jadwiga Jarocha, PhD, Paul Gadue, PhD, Wei Tong, PhD, Robert C Newton, PhD, Mortimer Poncz, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2559.
https://doi.org/10.1182/blood-2018-99-115407
Published: 2018
Journal Articles

Lnk/Sh2b3 Deficiency Restores Hematopoietic Stem Cell Function and Genome Integrity in Fanconi Anemia

Wei Tong, PhD, Joanna Balcerek, PhD, Jing Jiang, PhD, Nicholas Holdreith, MS, Qinqin Jiang, Krasimira A. Rozenova, PhD, Weihua Li, Roger A Greenberg
Journal: Blood
Blood (2017) 130 (Supplement 1): 1134.
https://doi.org/10.1182/blood.V130.Suppl_1.1134.1134
Published: 2017
Journal Articles

LNK (SH2B3) Deficiency Ameliorates Hematopoietic Stem Cell Defects in Fanconi Anemi

Joanna Balcerek, Jing Jiang, PhD, Qinqin Jiang, Kaosheng Lyu, PhD, Roger Greenberg, MD PhD, Wei Tong, PhD
Journal: Blood
Blood (2016) 128 (22): 2670.
https://doi.org/10.1182/blood.V128.22.2670.2670
Published: 2016
Journal Articles

Control of JAK2 Ubiquitination and Stability By CBL Family E3 Ubiquitin Ligases in Hematopoietic Stem/Progenitor Cells and Myeloid Malignancies

Kaosheng Lyu, PhD, Jing Jiang, PhD, Wei An, PhD, Wallace Y Langdon, PhD, Hamid Band, MD PhD, Wei Tong, PhD
Journal: Blood
Blood (2016) 128 (22): 723.
https://doi.org/10.1182/blood.V128.22.723.723
Published: 2016
Journal Articles

SH2B3/LNK Loss of Function Promotes Atherosclerosis and Thrombosis

Wei Wang, MD, Yang Tang, MD, Ying Wang, MD PhD, Joanna Balcerek, PhD, Wei Tong, PhD, Ross L. Levine, MD, Carrie Welch, PhD, Alan Tall, MD, Nan Wang, PhD
Journal: Blood
Blood (2015) 126 (23): 3443.
https://doi.org/10.1182/blood.V126.23.3443.3443
Published: 2015
Journal Articles

MERIT40 deficiency expands hematopoietic stem cell pools by regulating thrombopoietin receptor signaling

Krasimira Rozenova, Jing Jiang, Ryan Donaghy, Bernadette Aressy, Roger A. Greenberg, Wei Tong
Journal: Blood
Blood (2015) 125 (11): 1730–1738.
https://doi.org/10.1182/blood-2014-07-588145
Published: 2015
Includes: Supplemental data
Journal Articles

LNK (SH2B3) Synergizes with TP53 in Suppressing B-Precursor Acute Lymphoblastic Leukemia through IL-7 Receptor Signaling

Ying Cheng, PhD, Kudakwashe Chikwava, MD, Chao Wu, MS, Anchit Bhagat, MS, John K. Choi, MD, Wei Tong, PhD
Journal: Blood
Blood (2014) 124 (21): 1074.
https://doi.org/10.1182/blood.V124.21.1074.1074
Published: 2014
Journal Articles

Investigating The Role Of ARAP3 In The Regulation Of Hematopoietic Stem and Progenitor Cells

Yiwen Song, Sonja Vermeren, PhD, Wei Tong, PhD
Journal: Blood
Blood (2013) 122 (21): 2409.
https://doi.org/10.1182/blood.V122.21.2409.2409
Published: 2013
Journal Articles

Dual Role Of MERIT40 In Hematopoietic Stem and Progenitor Cells

Krasimira Rozenova, PhD, Jing Jiang, PhD, Chao Wu, Junmin Wu, Bernadette Aressy, PhD, Roger Greenberg, MD, PhD, Wei Tong, PhD
Journal: Blood
Blood (2013) 122 (21): 797.
https://doi.org/10.1182/blood.V122.21.797.797
Published: 2013