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Varun Sudunagunta
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Journal Articles

STAG2 mutation preserves a stem cell phenotype in FLT3-ITD-mediated MDS to leukemia transformation

Free
Jane J Xu, Yi Chen, John Pantazi, Sebastian Fernando, Besmira Alija, Varun Sudunagunta, Robert Bowman, Aaron Viny
Journal: Blood
Blood (2025) 146 (Supplement 1): 3242.
https://doi.org/10.1182/blood-2025-3242
Published: 2025
Journal Articles

Longitudinal single-cell spatial proteomics reveals predictive immune and stem cell signatures in Relapsed/Refractory AML

Free
Varun Sudunagunta, Stefan Petkov, Rongjia Deng, Yi Chen, Sebastian Fernando, Edna Stewart, Michele Simonetti, Sunil Iyer, Monica Kasbekar, Daniel Lee, Mark Frattini, Simon Fredriksson, Joseph Jurcic, Todd Rosenblat, Aaron Viny
Journal: Blood
Blood (2025) 146 (Supplement 1): 1696.
https://doi.org/10.1182/blood-2025-1696
Published: 2025
Journal Articles

Stag2 dependent chromatin remodeling enforces the erythroid-specific Gata1 cistrome

Free
Varun Sudunagunta, Edna Stewart, Yi Chen, Hongxia Yan, Sebastian Fernando, Viviana Scoca, Jane J Xu, Mohandas Narla, Aaron Viny
Journal: Blood
Blood (2025) 146 (Supplement 1): 968.
https://doi.org/10.1182/blood-2025-968
Published: 2025
Journal Articles

Enhanced FLI1 accessibility mediates STAG2-mutant leukemogenesis

Free
Jane J Xu, Viviana Scoca, Yi Chen, Yingqian Zhang, Alexander Fischer, Eno-obong Udoh, Sebastian Fernando, Besmira Alija, John Pantazi, Varun Sudunagunta, Edna Stewart, Anabella Maria D, Michael Williams, Govind Bhagat, Claudia Gebhard, Valeria Visconte, Sarah Ondrejka, Ruud Delwel, Ming Hu, Richard Koche, Aaron Viny
Journal: Blood
Blood (2025) 146 (Supplement 1): 1467.
https://doi.org/10.1182/blood-2025-1467
Published: 2025
Journal Articles

Synergy of Stag2-Cohesin Loss Results in Expansion of Npm1c-Mutant Hematopoietic Stem and Progenitor Cells

Free
Jane J Xu, Yi Chen, John Pantazi, Sebastian Fernando, Besmira Alija, Varun Sudunagunta, Govind Bhagat, Aaron D. Viny
Journal: Blood
Blood (2023) 142 (Supplement 1): 954.
https://doi.org/10.1182/blood-2023-190627
Published: 2023
Journal Articles

Stag2-Cohesin Loss Attenuates Flt3 ITD Myeloid Blast Expansion Yet Preserves Mutant HSC

Free
Jane J Xu, Yi Chen, John Pantazi, Sebastian Fernando, Besmira Alija, Varun Sudunagunta, Govind Bhagat, Robert L. Bowman, Aaron D. Viny
Journal: Blood
Blood (2023) 142 (Supplement 1): 2756.
https://doi.org/10.1182/blood-2023-190702
Published: 2023
Journal Articles

RUNX-1 haploinsufficiency causes a marked deficiency of megakaryocyte-biased hematopoietic progenitor cells

Free
Brian Estevez, Sara Borst, Danuta Jarocha, Varun Sudunagunta, Michael Gonzalez, James Garifallou, Hakon Hakonarson, Peng Gao, Kai Tan, Paul Liu, Sumedha Bagga, Nicholas Holdreith, Wei Tong, Nancy Speck, Deborah L. French, Paul Gadue, Mortimer Poncz
Journal: Blood
Blood (2021) 137 (19): 2662–2675.
https://doi.org/10.1182/blood.2020006389
Published: 2021
Includes: Supplemental data
Journal Articles

The Inherited Platelet Disorder of RUNX1 Haploinsufficiency (Familial Platelet Disorder with Associated Myeloid Malignancy (FPDMM)) Has a Marked Deficiency of Megakaryocyte-Biased Hematopoietic Progenitor Cells: Mechanistic Studies and Drug Correction

Free
Brian Estevez, PhD, Sara Borst, BS, Danuta Jadwiga Jarocha, PhD, Varun Sudunagunta, Michael Gonzalez, PhD, Peng Gao, Kai Tan, Deborah L French, PhD, Paul Gadue, PhD, Mortimer Poncz, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 220.
https://doi.org/10.1182/blood-2019-124851
Published: 2019