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Brian Estevez
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Journal Articles

RUNX1-deficient human megakaryocytes demonstrate thrombopoietic and platelet half-life and functional defects

Kiwon Lee, Hyun Sook Ahn, Brian Estevez, Mortimer Poncz
Journal: Blood
Blood (2023) 141 (3): 260–270.
https://doi.org/10.1182/blood.2022017561
Published: 2023
Includes: Supplemental data
Journal Articles

RUNX-1 haploinsufficiency causes a marked deficiency of megakaryocyte-biased hematopoietic progenitor cells

Brian Estevez, Sara Borst, Danuta Jarocha, Varun Sudunagunta, Michael Gonzalez, James Garifallou, Hakon Hakonarson, Peng Gao, Kai Tan, Paul Liu, Sumedha Bagga, Nicholas Holdreith, Wei Tong, Nancy Speck, Deborah L. French, Paul Gadue, Mortimer Poncz
Journal: Blood
Blood (2021) 137 (19): 2662–2675.
https://doi.org/10.1182/blood.2020006389
Published: 2021
Includes: Supplemental data
Journal Articles

RGS10 and RGS18 differentially limit platelet activation, promote platelet production, and prolong platelet survival

Daniel DeHelian, Shuchi Gupta, Jie Wu, Chelsea Thorsheim, Brian Estevez, Matthew Cooper, Kelly Litts, Melissa M. Lee-Sundlov, Karin M. Hoffmeister, Mortimer Poncz, Peisong Ma, Lawrence F. Brass
Journal: Blood
Blood (2020) 136 (15): 1773–1782.
https://doi.org/10.1182/blood.2019003251
Published: 2020
Includes: Multimedia, Supplemental data
Journal Articles

The Inherited Platelet Disorder of RUNX1 Haploinsufficiency (Familial Platelet Disorder with Associated Myeloid Malignancy (FPDMM)) Has a Marked Deficiency of Megakaryocyte-Biased Hematopoietic Progenitor Cells: Mechanistic Studies and Drug Correction

Brian Estevez, PhD, Sara Borst, BS, Danuta Jadwiga Jarocha, PhD, Varun Sudunagunta, Michael Gonzalez, PhD, Peng Gao, Kai Tan, Deborah L French, PhD, Paul Gadue, PhD, Mortimer Poncz, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 220.
https://doi.org/10.1182/blood-2019-124851
Published: 2019
Journal Articles

Signaling-mediated cooperativity between glycoprotein Ib-IX and protease-activated receptors in thrombin-induced platelet activation

Brian Estevez, Kyungho Kim, M. Keegan Delaney, Aleksandra Stojanovic-Terpo, Bo Shen, Changgeng Ruan, Jaehyung Cho, Zaverio M. Ruggeri, Xiaoping Du
Journal: Blood
Blood (2016) 127 (5): 626–636.
https://doi.org/10.1182/blood-2015-04-638387
Published: 2016
Includes: Multimedia, Supplemental data
Journal Articles

A Signaling Mechanism By Which Platelet Glycoprotein Ib-IX Promotes Thrombin-Induced Platelet Activation

Brian Estevez, BA, Michael Keegan Delaney, BS, Aleksandra Stojanovic-Terpo, MS, Xiaoping Du, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2759.
https://doi.org/10.1182/blood.V124.21.2759.2759
Published: 2014
Journal Articles

LIM kinase-1 selectively promotes glycoprotein Ib-IX–mediated TXA 2 synthesis, platelet activation, and thrombosis

Brian Estevez, Aleksandra Stojanovic-Terpo, M. Keegan Delaney, Kelly A. O’Brien, Michael C. Berndt, Changgeng Ruan, Xiaoping Du
Journal: Blood
Blood (2013) 121 (22): 4586–4594.
https://doi.org/10.1182/blood-2012-12-470765
Published: 2013