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Journal Articles

Differential diagnosis of bone marrow failure syndromes guided by machine learning

Blood (2023) 141 (17): 2100–2113.

https://doi.org/10.1182/blood.2022017518

Published: 2023

Includes: Supplemental data

Journal Articles

A RUNX1 -FPDMM rhesus macaque model reproduces the human phenotype and predicts challenges to curative gene therapies

Byung-Chul Lee, Yifan Zhou, Erica Bresciani, Neval Ozkaya, Alina Dulau-Florea, Blake Carrington, Tae-Hoon Shin, Valentina Baena, Zulfeqhar A. Syed, So Gun Hong, Tao Zhen, Katherine R. Calvo, Paul Liu, Cynthia E. Dunbar

Blood (2023) 141 (3): 231–237.

https://doi.org/10.1182/blood.2022018193

Published: 2023

Includes: Supplemental data

Journal Articles

RUNX-1 haploinsufficiency causes a marked deficiency of megakaryocyte-biased hematopoietic progenitor cells

Brian Estevez, Sara Borst, Danuta Jarocha, Varun Sudunagunta, Michael Gonzalez, James Garifallou, Hakon Hakonarson, Peng Gao, Kai Tan, Paul Liu, Sumedha Bagga, Nicholas Holdreith, Wei Tong, Nancy Speck, Deborah L. French, Paul Gadue, Mortimer Poncz

Blood (2021) 137 (19): 2662–2675.

https://doi.org/10.1182/blood.2020006389

Published: 2021

Includes: Supplemental data

Journal Articles

RUNX1 and CBFβ-SMMHC transactivate target genes together in abnormal myeloid progenitors for leukemia development

Tao Zhen, Yaqiang Cao, Gang Ren, Ling Zhao, R. Katherine Hyde, Guadalupe Lopez, Dechun Feng, Lemlem Alemu, Keji Zhao, P. Paul Liu

Blood (2020) 136 (21): 2373–2385.

https://doi.org/10.1182/blood.2020007747

Published: 2020

Includes: Supplemental data

Journal Articles

Chd7 deficiency delays leukemogenesis in mice induced by Cbfb-MYH11

Tao Zhen, Erika M. Kwon, Ling Zhao, Jingmei Hsu, R. Katherine Hyde, Ying Lu, Lemlem Alemu, Nancy A. Speck, P. Paul Liu

Blood (2017) 130 (22): 2431–2442.

https://doi.org/10.1182/blood-2017-04-780106

Published: 2017

Includes: Supplemental data

Journal Articles

Role of RUNX1 in hematological malignancies

Raman Sood, Yasuhiko Kamikubo, Paul Liu

Blood (2017) 129 (15): 2070–2082.

https://doi.org/10.1182/blood-2016-10-687830

Published: 2017

Journal Articles

Runx1 Deficiency and MDS-Associated U2af1 Mutation Cooperate for Leukemia Development in a New Mouse Model

Tao Zhen, PhD, Dennis Liang Fei, PhD, Ling Zhao, MD PhD, Guadalupe Lopez, Harold Varmus, MD, Pu Paul Liu, MD PhD

Blood (2016) 128 (22): 964.

https://doi.org/10.1182/blood.V128.22.964.964

Published: 2016

Journal Articles

RUNX1 and CBFB-MYH11 Are Required for the Maintenance of Inv(16) AML

Yiqian Wang, Kira Hannon, Lisa Richter, Michelle Becker, Lisa Garett, Cecilia Rivas, Lemlem Alemu, Ling Zhao, MD PhD, Pu Paul Liu, MD PhD, R. Katherine Hyde, PhD

Blood (2016) 128 (22): 2715.

https://doi.org/10.1182/blood.V128.22.2715.2715

Published: 2016

Journal Articles

Runx1 Is Strictly Required for Cbfb-MYH11 Induced Leukemia Development

Tao Zhen, PhD, Erika Mijin Kwon, PhD, R. Katherine Hyde, PhD, Ling Zhao, MD PhD, Guadalupe Lopez, Lemlem Alemu, Pu Paul Liu, MD PhD

Blood (2016) 128 (22): 2722.

https://doi.org/10.1182/blood.V128.22.2722.2722

Published: 2016

Journal Articles

The Roles of RUNX1 in Human Hematopoiesis and Megakaryopoiesis Revealed By Genome-Targeted Human iPSCs and an Improved Hematopoietic Differentiation Model

Bin-Kuan Chou, PhD, Hao Bai, PhD, Yongxing Gao, Ying Wang, Zhaohui Ye, PhD, Erika Mijin Kwon, PhD, Pu Paul Liu, MD PhD, Alan D. Friedman, MD, Zack Z. Wang, PhD, Linzhao Cheng, PhD

Blood (2015) 126 (23): 1167.

https://doi.org/10.1182/blood.V126.23.1167.1167

Published: 2015

Journal Articles

CHD7 Deficiency Inhibits CBFB-MYH11 -Induced Leukemogenesis

Tao Zhen, PhD, Ling Zhao, MD PhD, R. Katherine Hyde, PhD, Lemlem Alemu, Pu Paul Liu, MD PhD

Blood (2015) 126 (23): 3662.

https://doi.org/10.1182/blood.V126.23.3662.3662

Published: 2015

Journal Articles

The Multimerization Domain of Cbfß-SMMHC Is Required for Leukemogenesis

Ling Zhao, MD PhD, Lemlem Alemu, Jun Cheng, Tao Zhen, PhD, Alan D. Friedman, MD, Pu Paul Liu, MD PhD

Blood (2015) 126 (23): 3666.

https://doi.org/10.1182/blood.V126.23.3666.3666

Published: 2015

Journal Articles

Functional Dissection of the C Terminus of CBFβ-SMMHC Indicates a Critical Role of the Multimerization Domain during Hematopoiesis and Leukemogenesis

Ling Zhao, MD PhD, Lemlem Alemu, Jun Cheng, Tao Zhen, PhD, Alan D. Friedman, MD, Pu Paul Liu, MD PhD

Blood (2014) 124 (21): 2218.

https://doi.org/10.1182/blood.V124.21.2218.2218

Published: 2014

Journal Articles

Somatic Mutational Landscape of AML with Inv(16) and t(8;21) Identifies Two Distinct Patterns in Relapse Tumors

Raman B. Sood, PhD, Nancy F Hansen, Frank X Donovan, Blake Carrington, Baishali Maskeri, Alice Young, Donna Bucci, Settara Chandrasekharaappa, James C Mullikin, Clara D. Bloomfield, MD, Guido Marcucci, MD, Paul Liu

Blood (2014) 124 (21): 2362.

https://doi.org/10.1182/blood.V124.21.2362.2362

Published: 2014

Journal Articles

Targeted correction of RUNX1 mutation in FPD patient-specific induced pluripotent stem cells rescues megakaryopoietic defects

Jon P. Connelly, Erika M. Kwon, Yongxing Gao, Niraj S. Trivedi, Abdel G. Elkahloun, Marshall S. Horwitz, Linzhao Cheng, P. Paul Liu

Blood (2014) 124 (12): 1926–1930.

https://doi.org/10.1182/blood-2014-01-550525

Published: 2014

Includes: Supplemental data

Journal Articles

CBFβ and RUNX1 are required at 2 different steps during the development of hematopoietic stem cells in zebrafish

Erica Bresciani, Blake Carrington, Stephen Wincovitch, MaryPat Jones, Aniket V. Gore, Brant M. Weinstein, Raman Sood, P. Paul Liu

Blood (2014) 124 (1): 70–78.

https://doi.org/10.1182/blood-2013-10-531988

Published: 2014

Includes: Multimedia, Supplemental data

Journal Articles

Zebrafish Cbfb Is Required For The Mobilization, But Not The Emergence, Of Hematopoietic Stem Cells In Embryos

Erica Bresciani, PhD, Blake Carrington, Stephen Wincovitch, Aniket Gore, Brant M. Weinstein, PhD, Raman B. Sood, PhD, Paul Liu

Blood (2013) 122 (21): 464.

https://doi.org/10.1182/blood.V122.21.464.464

Published: 2013

Journal Articles

Targeted correction Of RUNX1 Mutation In The FPD Patient-Specific Induced Pluripotent Stem Cells Restores Megakaryocytic Differentiation

Erika Mijin Kwon, PhD, Jon P Connelly, PhD, Yongxing Gao, BS, Marshall Horwitz, MD, PhD, Linzhao Cheng, PhD, Pu Paul Liu, MD, PhD

Blood (2013) 122 (21): 738.

https://doi.org/10.1182/blood.V122.21.738.738

Published: 2013

Journal Articles

The C-terminus of CBFβ-SMMHC is required to induce embryonic hematopoietic defects and leukemogenesis

Yasuhiko Kamikubo, R. Katherine Hyde, Ling Zhao, Lemlem Alemu, Cecilia Rivas, Lisa J. Garrett, P. Paul Liu

Blood (2013) 121 (4): 638–642.

https://doi.org/10.1182/blood-2012-06-434688

Published: 2013

Includes: Supplemental data

Journal Articles

The HOXA/PBX3 Pathway Is an Attractive Therapeutic Target in MLL -Rearranged Acute Leukemia

Blood (2012) 120 (21): 3522.

https://doi.org/10.1182/blood.V120.21.3522.3522

Published: 2012

NARROW

Differential diagnosis of bone marrow failure syndromes guided by machine learning

A RUNX1 -FPDMM rhesus macaque model reproduces the human phenotype and predicts challenges to curative gene therapies

RUNX-1 haploinsufficiency causes a marked deficiency of megakaryocyte-biased hematopoietic progenitor cells

RUNX1 and CBFβ-SMMHC transactivate target genes together in abnormal myeloid progenitors for leukemia development

Chd7 deficiency delays leukemogenesis in mice induced by Cbfb-MYH11

Role of RUNX1 in hematological malignancies

Runx1 Deficiency and MDS-Associated U2af1 Mutation Cooperate for Leukemia Development in a New Mouse Model

RUNX1 and CBFB-MYH11 Are Required for the Maintenance of Inv(16) AML

Runx1 Is Strictly Required for Cbfb-MYH11 Induced Leukemia Development

The Roles of RUNX1 in Human Hematopoiesis and Megakaryopoiesis Revealed By Genome-Targeted Human iPSCs and an Improved Hematopoietic Differentiation Model

CHD7 Deficiency Inhibits CBFB-MYH11 -Induced Leukemogenesis

The Multimerization Domain of Cbfß-SMMHC Is Required for Leukemogenesis

Functional Dissection of the C Terminus of CBFβ-SMMHC Indicates a Critical Role of the Multimerization Domain during Hematopoiesis and Leukemogenesis

Somatic Mutational Landscape of AML with Inv(16) and t(8;21) Identifies Two Distinct Patterns in Relapse Tumors

Targeted correction of RUNX1 mutation in FPD patient-specific induced pluripotent stem cells rescues megakaryopoietic defects

CBFβ and RUNX1 are required at 2 different steps during the development of hematopoietic stem cells in zebrafish

Zebrafish Cbfb Is Required For The Mobilization, But Not The Emergence, Of Hematopoietic Stem Cells In Embryos

Targeted correction Of RUNX1 Mutation In The FPD Patient-Specific Induced Pluripotent Stem Cells Restores Megakaryocytic Differentiation

The C-terminus of CBFβ-SMMHC is required to induce embryonic hematopoietic defects and leukemogenesis

The HOXA/PBX3 Pathway Is an Attractive Therapeutic Target in MLL -Rearranged Acute Leukemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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